KDIGO Overview
www.kdigo.org
KDIGO
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Mission
Governance
Clinical Practice Guidelines
Controversies Conferences
Guideline Coordination
Guideline Implementation
Website
Kidney Disease: Improving Global Outcomes
www.kdigo.org
KDIGO Mission
Kidney Disease: Improving Global Outcomes
www.kdigo.org
KDIGO
An independently incorporated nonprofit
foundation, governed by an international board,
with the stated mission to:
‘Improve the care and outcomes of kidney
disease patients worldwide through promoting
coordination, collaboration, and integration of
initiatives to develop and implement clinical
practice guidelines.’
Kidney Disease: Improving Global Outcomes
www.kdigo.org
KDIGO Governance
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Organizational Structure
Nominating
committee
Board of Councelors
(retired BOD members)
Board
Management:
National Kidney
Foundation
Executive Committee
Evidence review:
Evidence Review
Team
Tufts NEMC
KDIGO Workgroups
- CPG Workgroups
- Liaison Task Force
- Implementation Task Force
Kidney Disease: Improving Global Outcomes
Foundation under Belgium law
www.kdigo.org
KDIGO Board of Directors
Co-Chairs: Kai-Uwe Eckardt, MD GERMANY
Bertram Kasiske, MD USA
Omar I. Abboud, MD, SUDAN
Sharon Adler, MD, USA
Rajiv Agarwal, USA
Sharon P. Andreoli, MD, USA
Robert Atkins, MD, AUSTRALIA
Gavin Becker, MD, AUSTRALIA
Fred Brown, MBA, USA
Daniel Cattran, MD, CANADA
Allan Collins, MD, USA
Josef Coresh, MD, USA
Ricardo Correa-Rotter, MD, MEXICO
Adrian Covic, MD, ROMANIA
Jonathon Craig, MD, AUSTRALIA
Angel de Francisco, MD, SPAIN
Paul de Jong, MD, NETHERLANDS
Tilman Drüeke, MD, FRANCE
Ana Figueiredo, RN, BRAZIL
Mohammed Benghanem Gharbi, MD,
MORROCO
Gordon Guyatt, MD, CANADA
Philip Halloran, MD, CANADA
David Harris, MD, AUSTRALIA
Enyu Imai, MD, JAPAN
Kidney Disease: Improving Global Outcomes
www.kdigo.org
KDIGO Board of Directors
Michel Jadoul, MD, BELGIUM
Simon Jenkins, Patient, UK
Bernardo Rodriguez-Iturbe, MD,
VENEZUELA
Vivekanand Jha, MD, INDIA
Robert Schrier, MD USA
Suhnggwon Kim, MD, KOREA
Hooi Lai Seong, MD, MALAYSIA
Justin Silver, MD, ISRAEL
Lesley Stevens, MD, USA
Marcello Tonelli, CANADA
Yusuke Tsukamoto, MD, JAPAN
Martin Kuhlmann, MD, GERMANY
Nathan Levin, MD, USA
Phillip K.T. Li, MD, HONG KONG
Zhi-Hong Liu, MD, CHINA
Pablo Massari, MD, ARGENTINA
Peter McCullough, MD, USA
Rafique Moosa, MD, SOUTH AFRICA
Theodor Vogels, MSW, NETHERLANDS
David Wheeler, MD, UK
Elena Zakharova, MD, RUSSIA
Miguel C. Riella, MD, BRAZIL
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Executive Committee
Co-chairs:
Kai-Uwe Eckardt
Bertram Kasiske
Germany
United States
Past co-chairs:Norbert Lameire
Garabed Eknoyan
Belgium
United States
Members:
United States
Australia
Spain
Belgium
United States
Brazil
United States
Japan
United Kingdom
Josef Coresh
Jonathon Craig
Angel de Francisco
Michel Jadoul
Nathan Levin
Miguel Riella
Robert Schrier
Yusuke Tsukamoto
David Wheeler
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Clinical Practice Guidelines
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Guiding Principles for KDIGO
Guideline Development
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Scientific and methodological rigor
Interdisciplinary approach
Independence of work groups
Transparency of the guideline development
process
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Grading: The Quality of the Evidence and
the Strength of the Recommendation
• 2 components of final grade:  granularity and transparency
• Although quality of evidence influences strength of recommendation,
no direct link
• “Neutral“ alphanumeric code instead of terms that may be interpreted differently
Quality
of
evidence
High
A
Moderate
B
Low
C
Very low
D
Strength of
recommendation
1
Corresponds to
“strong“ in GRADE
2
Corresponds to
“weak“ in GRADE
e.g. (Grade 1C) or (Grade 2D) ……(8 options)
Plus option to include statements that are not graded
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Published Clinical Practice
Guidelines
• Prevention, Diagnosis, Evaluation, and
Treatment of Hepatitis C in CKD
– Published in Kidney International in April, 2008
• Diagnosis, Evaluation, Prevention, and
Treatment of CKD-MBD
– Published in Kidney International in July, 2009
• Care of Kidney Transplant Recipients
– Published in the American Journal of Transplantation
in October, 2009; Executive Summary published in
Kidney International in December, 2009
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Guidelines in Development
• Acute Kidney Injury
– Chairs: John Kellum & Norbert Lameire
– Anticipated Publication: June, 2011
• Glomerulonephritis
– Chairs: John Feehally & Dan Cattran
– Anticipated Publication: August, 2011
• Blood Pressure in CKD
– Chairs: Gavin Becker & David Wheeler
– Anticipated Publication: October, 2011
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Guidelines in Development
• Anemia in CKD
– Chairs: John McMurray and Patrick Parfrey
– Anticipated Publication: November, 2011
• CKD Classification and Treatment
– Chairs: Adeera Levin and Paul Stevens
– Anticipated Publication: July, 2012
• Lipids in CKD
– Chairs: Marcello Tonelli and Christoph Wanner
– Anticipated Publication: August, 2013
• Peritoneal Dialysis
– Chairs: Philip Li and
– Anticipated Publication: 2013
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Controversies Conferences
Kidney Disease: Improving Global Outcomes
www.kdigo.org
2010 KDIGO Controversies
Conferences
• Drug Prescribing in Kidney Disease:
Initiative for Improved Dosing (May 2010)
Co-chairs: George Aronoff and Patrick Murray
• Cardiovascular Disease in CKD: What is it
and what can we do about it? (October 2010)
Co-chairs: Eberhard Ritz and Charles Herzog
Kidney Disease: Improving Global Outcomes
www.kdigo.org
2011 Planned KDIGO
Controversies Conferences
• Novel Dialysis Techniques (October
2011)
Co-Chairs: Christopher Chan, Nathan Levin and
Francesco Locatelli
• Diabetes in CKD (March 2012)
Co-Chairs: Mark Molitch and Carl Mogensen
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Guideline Coordination
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Collaborating Guideline Groups
• Canadian Society of Nephrology (CSN) Guidelines
• Caring for Australians with Renal Impairment (CARI)
Guidelines - ANZSN
• United Kingdom Renal Association Guidelines
• European Renal Best Practice (ERBP) –
ERA/EDTA
• Kidney Disease Outcomes Quality Initiative (KDOQI)
Guidelines – NKF
• ISN Guideline Committee
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Guideline Coordination
• Liaison Task Force
• Global Guideline Coordination Group
• ISN/KDIGO Collaboration Group
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Guideline Implementation
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Guideline Implementation
• Publish Guidelines in multiple languages on
KDIGO website and in regional journals
• Commentaries from ISN, KDOQI, ERBP, UKRA, CARI, and CSN
• Develop professional education tools based on
KDIGO Guidelines
• KDIGO Implementation Task Force
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Implementation Task Force
The KDIGO Implementation Task Force is
charged with promoting awareness,
dissemination, adoption and clinical
integration of KDIGO Clinical Practice
Guidelines locally, around the world.
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Implementation Task Force
• Task Force divided into 6 regions
• Each Task Force Leader has designated
Regional Representatives from the
countries within their region
• There will be different approaches to
guideline dissemination depending on the
region and on the country
Kidney Disease: Improving Global Outcomes
Type the Presentation Title here – Type the Presentation Subtitle here
www.kdigo.org
KDIGO Implementation Task
Force
LEADER
REGION
Yusuke Tsukamoto (Chair) Asia Pacific
Michelle Josephson
North America
Miguel Riella
Latin America
Michel Jadoul
Western Europe
Andrzej Więcek
Eastern Europe
Mona Al Rukhaimi
Middle East/Africa
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Implementation Task Force
Activities:
• Facilitate and increase the number of
presentations on KDIGO guidelines at local,
national, and regional meetings.
• Translate and submit guideline translations and
executive summaries to regional journals for
publication.
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Implementation Task Force
Activities:
• Promote integration and adoption of
guidelines into residency training programs.
• Assist in developing commentaries / editorials
on KDIGO Guidelines for publication in
regional journals.
• Communicate with regional healthcare
administrators to promote adoption of practice
guidelines.
Kidney Disease: Improving Global Outcomes
www.kdigo.org
KDIGO Website
www.kdigo.org
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Website Resources
• KDIGO Guidelines:
– All published guidelines available
– Recommendations translated into multiple
languages
– Slide presentations
• Reports from Controversies Conferences
– Published position statements
– Conference presentations
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Website Resources
• Global Nephrology Guideline
Database:
– Guideline Overviews by Organization
– Guideline Summaries by Clinical Topic
Kidney Disease: Improving Global Outcomes
www.kdigo.org
Thank you
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