The 2nd generation of Fractional Tx. ® With CIS-F1 Understanding What is LASER ? www.sellas.kr www.sellaslaser.com L : Light A S E R : Amplification : by Stimulated : Emission : of Radiation 2 Diagram of a laser www.sellas.kr www.sellaslaser.com Diagram of a laser www.sellas.kr www.sellaslaser.com What makes laser different from other light Sources? www.sellas.kr www.sellaslaser.com ■ ■ ■ Monochromaticity Coherence : the waves are in phase in time and space. Collimation Laser and Tissue Interaction: Laser targets chromophore www.sellas.kr www.sellaslaser.com For effective use of laser, practitioners must understand ‘Laser tissue interaction ’ Laser and Tissue Interaction: Laser targets chromophore www.sellas.kr www.sellaslaser.com Typical chromophores (chromophores’ absorbing laser in tissue): - Water (Chromophore of CIS-F1) - Hemoglobin and Oxy-hemoglobin - Melanin (including Hair) Laser and Tissue Interaction www.sellas.kr www.sellaslaser.com Laser interacts with tissue by absorption, scatter and/or transmission. X Transmission V Without incident angle “Laser light must be perpendicular with skin surface to minimize refraction” Reflection : 4-7% on skin surface Absorption Refraction Scatter Grothus Draper Law : Laser application of tissue is based on the absorption. “No Absorption No Effect” Laser Tissue Absorption Spectrum www.sellas.kr www.sellaslaser.com 585 nm (Pulsed Dye) 20000 2940 nm (Er:YAG) 532 nm (KTP) 1550 nm (Er:Glass) 10,600 nm (CO2) Hb 1000 100 HbO2 10 1 0.1 200 1000 5000 3 Skin Layers www.sellas.kr www.sellaslaser.com Laser and Tissue Interaction www.sellas.kr www.sellaslaser.com Ablative Laser (CIS-F1) LASER Vaporization (>100 ºC) Necrosis & Coagulation (58-85 ºC) Protein Denaturation (> 60 ºC) Benefit Injury Photobiomodulation (< 40 ºC) Laser and Tissue Interaction www.sellas.kr www.sellaslaser.com Fractional irradiation Fractional Tx. delivers multiful micro-beams, which hits the surface of skin in a fractionated manner and allows for fast healing by intact surrounding healthy Tissues. Benefit Laser and Tissue Interaction www.sellas.kr www.sellaslaser.com Cytokine GF Skin Tissue Interaction(CIS-F1) www.sellas.kr www.sellaslaser.com 10mJ, Moving mode (50mm tip) Depth: 230㎛ Width: 80 ㎛ ** Slides of porcine skin 250mJ, Stamp mode (50mm tip) Depth: 1800㎛ Width: 150 ㎛ 200mJ, Stamp mode (100mm tip) Depth: 1350㎛ Width: 200 ㎛ Selective Photothermolysis www.sellas.kr www.sellaslaser.com Laser Light Absorbed Target Non absorbed target *Temperature in the absorbed target will rise. Termal Relaxation Time(TRT) www.sellas.kr www.sellaslaser.com Small Blood Vessels are Typically <450 us Melanosome is Typically <10ns to 100 ns Comparison www.sellas.kr www.sellaslaser.com CIS-F1 (10600㎛ fractional) Sellas-evo (1550㎛ fractional) Ablative approach Non-ablative approach Excellent in skin resurfacing Excellent in skin rejuvenation More effective on single Tx. Minimal downtime Require less than 3 Tx. Require less than 5 Tx. Combination enhancement Combination enhancement Prone to surface of skin Tx. (face lift effect) Prone to dermis Tx. (face volume up effect) -Termal peeling. -How it works. www.sellas.kr www.sellaslaser.com –Structural change in Keratinized outer layer (enhance absorption of topicals) –Biomodulation < 40˚C (Activity of cytokine ) –Stimulation of functional cells (Cytokine,GF…) CIS-F1 www.sellas.kr www.sellaslaser.com ▪ Specification Laser source RF CO2 Laser Wavelength 10600nm Operation mode Stamping / Moving (Scanning) Pulse energy Stamp: 1-250mJ (Depth: 0.2~1.5mm) Moving: 1-50mJ Pattern size Handpiece diameter 30mm tip (microbeam dia. 150㎛) Interface Touch Screen Weight 30kg Dimension 40(W)x55(D)*90(H)cm CIS-F1 www.sellas.kr Tip length (Focal length) Microbeam Size Power Application 50mm 100mm 80㎛ 120㎛ Higher than 100mm tip applied Lower than 50mm tip applied Deep penetration (Deep scar) Skin resurfacing Surgical tip Incision, Cutting, Nevus removal CIS-F1 www.sellas.kr CIS-F1 www.sellas.kr User mode - easy to pick up the preset protocol Tailoring the treatment zone www.sellas.kr www.sellaslaser.com ▪ Tailoring the treatment zone by drawing on canvas (X-Y scanner). ▪ Customized design is allowed for intensive treatment without excessive damage to surrounding tissues. Tailoring the spot pattern Regular forms www.sellas.kr www.sellaslaser.com [ 16 standard regular forms] [ Max. 250mJ per micro dot] www.sellas.kr www.sellaslaser.com Cooling and topical anesthesia before “ high energy” procedures 30% lidocaine gel is applied on face; occlude for 30-40 mins with BioMask Terminology of Laser www.sellas.kr www.sellaslaser.com Dr. Gabriel Serrano, Spain Immediate redness after Sellas laser Terminology of Laser www.sellas.kr www.sellaslaser.com Stamping mode Dr. Gabriel Serrano, Spain Terminology of Laser www.sellas.kr www.sellaslaser.com Moving mode Dr. Gabriel Serrano, Spain Post-Care Treatment www.sellas.kr www.sellaslaser.com Factors: Moisturizing / Anti-inflammatory / Revitalization / Sunscreen • Sunscreen above SPF 50 • Vitamin C • Retinol at night • EGF, bFGF, Amino acid, Mineral, Co-enzymes, Necleonic acid • Copper peptide, Glyco-protein 1. Fast recovery against PIH after laser treatment (Whitening) 2. Improving skin tone and firmness (tightening). 3. Anti-aging restructuring of skin tissue 4. Post-trauma skin repair Post-Care Treatment www.sellas.kr www.sellaslaser.com Post CIS-F1 treatment: Immediate care & First week after treatment 1. C- Vit serum / Lotion + Factor G Lotion + Moisturizing pack 2. Sun screen 3. Away from excessive heat stimulus such as sauna, hot spa Post-Care Treatment www.sellas.kr www.sellaslaser.com [Medical examination and treatment after 1 week Restart skin care at home Skin Healing or tighten mask as for cosmetic care (propymask, Biomask) [Post CIS-F1 treatment]: Second week after treatment 1. Return to regular skin care: C-Vit Lotion + Factor G lotion (scars) RetiseS / Fillderma System (aging), C-Vit DaeSeS (DMAE) for flaccidity Kojic acid / Alfa lipoic / arbutin (bleaching) JuveSeS Teens / SaliSeS(acne) [Medical examination and treatment after 2 weeks]: Combine treatments Start aesthetic treatment with chemical peel, IPL, RF, Microdermabrasion, electroporation for complementary approach (Antiaging, Whitening, Tightening) [Second visit for CIS-F1 treatment after 4 weeks] Contraindication for Sellas www.sellas.kr www.sellaslaser.com 1. Renal failure 2. Herpes simplex 3. Acute infection 4.Post thermal injury Advantages www.sellas.kr www.sellaslaser.com •Fast high density delivery • Able to tailor stamping shape according to lesional shape • Thermal peeling Only Sellas can represent “True” 2nd generation fractional laser! Terminology of Laser www.sellas.kr www.sellaslaser.com PHOTOS (BEFORE/AFTER) Skin Photo Gallery www.sellas.kr www.sellaslaser.com Patient age: 28 (Skin type: IV) After 3 Tx Skin Photo Gallery www.sellas.kr www.sellaslaser.com Patient age: 27 (Skin type: IV) After 3 Tx Skin Photo Gallery www.sellas.kr www.sellaslaser.com Patient age: 27 (Skin type: IV) After 3 Tx Skin Photo Gallery www.sellas.kr www.sellaslaser.com Patient age: 29 (Skin type: IV) After 5 Tx Skin Photo Gallery www.sellas.kr www.sellaslaser.com Patient age: 32 (Skin type: IV) After 3 Tx Skin Photo Gallery www.sellas.kr www.sellaslaser.com Patient age: 32 (Skin type: IV) After 3 Tx Patient age: 46 (Skin type: IV) After 3 Tx Skin Photo Gallery www.sellas.kr www.sellaslaser.com Patient age: 25 (Skin type: IV) After 3 Tx www.sellas.kr www.sellaslaser.com The 2nd Generation of Fractional ® Ablative Tx. With CIS-F1 Thank you.