Superior Performance of FN® Coatings (photocatalytic multifunctional nano coatings) MEDICAL APPLICATIONS FN® Coatings Apply in … And say „no more“ to … • Living rooms, bedrooms, kids rooms • Kitchens and bathrooms • Hotels, spas, restaurants and cafeterias • Schools and nurseries • Hospitals and clinics • Offices and public areas • Headaches, lethargy, fatigue, and poor concentration • Respiratory illnesses and asthmas • Allergies and skin irritations • Virus and bacteria dispersion • Unpleasant odors, molds and dirt on walls WHY FN® COATINGS IN HOSPITALS AND MEDICAL FACILITIES? PATIENT AND PERSONNEL NOSOCOMIAL INFECTIONSPROTECTION MRSA SANITARY AND CLEAN ENVIRONMENT INFECTIONS OUTBREAKS OUTBREAK CONTROL OVEREXPOSURE FAST REMOVAL OF TO EXCESS OF DISINFECTIONS DISINFECTION AND AND CHEMICALS CHEMICALS INFECTION OUTBREAK FN® COATING INFECTION OUTBREAK CONTROL SOFT UVA ACTIVATION LIGHTS ON!!! THE AIR IS CLEAN IN ABOUT 1-2 HOURS • VIRUS CONCENTRATION STABILIZED UNDER THE INFECTION CRITICAL LEVEL • INFECTION LOCALIZED FN2 Non active 15 min FN2 Non active 30 min FN® ANTIMICROBIAL FUNCTION WAS PROVEN BY SEVERAL ACCREDITED LABS AND IN MANY PRACTICAL APPLICATIONS PUBLIC HEALTH PROTECTION VERY EFFICIENT NON-CHEMICAL SANITARY FUNCTION Microorganism UV UV Exposure Intensity time (min) mW/cm2 Bakteriofag E.Coli ΦX 174 60 min (MODEL VIRUS) 60 min 6 hours 6 hours 6 hours 6 hours 60 min Candida albicans Candida albicans 120 min 120 min Pseudomonas aeruginosa 120 min Pseudomonas aeruginosa 120 min START Reference sample END END concentration concentration (CFU) (CFU) BACTERIA REDUCTION ON FN2 SURFACE (%) 1.00E+06 1.00E+06 1.00E+08 1.00E+05 1.00E+08 1.00E+05 1.00E+06 99.9940% 99.9970% 99.9999% 100% 99.9996% 99.9850% 0% 1.00E+06 1.00E+06 100% 100% 100% 100% 99.99949% • HOSPITALS concentration • MEDICAL(CFU) CENTERS 0.2 ml •0.05-0.1 BIOLABS 1.00E+06 60 1.00E+06 30 •0.05-0.1 OFFICES 0.05-0.1 1.00E+08 88 1.00E+05 0 •0.05-0.1 SCHOOLS 1.00E+08 400 •0.05-0.1 KINDERGARTENS 0.05-0.1 1.00E+05 15 1.00E+06 •0-darkBANKS1.00E+06 0.2 ml •0.05-0.1 PUBLIC1.00E+06 BUILDINGS0 1.00E+06 STATIONS 0 •0.05-0.1 TRAIN/BUS 0.2 ml •0.05-0.1 AIRPORTS 1.00E+06 0 0.05-0.1 1.00E+06 0 1.00E+06 1.00E+06 1.50E+08 767 not countable 0.3 ml Enterococcus faecalis 4224 120 min 0.1-0.3 Candida albicans Pseudomonas aeruginosa Enterococcus faecalis E. faecalis can cause life-threatening infections in humans, especially in the nosocomial(hospital) environment, where the naturally high levels of antibiotic resistance found in E. faecalis contribute to its pathogenicity.[1] E. faecalis has been frequently found in root canal-treated teeth. Image courtesy of http://www.chuv.ch/ UV UV Exposure Intensity time (min) mW/cm2 Reference sample END END concentration concentration (CFU) (CFU) BACTERIA REDUCTION ON FN2 SURFACE (%) START Microorganism concentration (CFU) Yeast fungi: Candida albicans can cause serious Pseudomonas aeruginosa has become an important cause of 0.2 ml and potentially life-threatening infections in the infection, especially in patients with compromised host defense Bakteriofag E.Coli ΦX 174 60 min 0.05-0.1 1.00E+06 60 1.00E+06 99.9940% mouth, blood and other tissues of people who mechanisms. It is the most common pathogen isolated from (MODEL VIRUS) 60 min 0.05-0.1 1.00E+06 30 1.00E+06 99.9970% are undergoing cancer chemotherapy or patients who have been hospitalized longer than 1 week. It is a 6 hours 0.05-0.1 1.00E+08 88 1.00E+08 99.9999% radiation treatments, or who have developed frequent cause of nosocomial infections such as pneumonia, 6 hours 1.00E+05 0 1.00E+05 AIDS or other diseases that damage 0.05-0.1 the urinary tract infections (UTIs), and bacteremia. Pseudomonal100% 6 hours 0.05-0.1 1.00E+08are complicated 400 and can be 1.00E+08 immunity of the individual. infections life threatening. 99.9996% 6 hours 0.05-0.1 1.00E+05 15 1.00E+05 99.9850% 60 min 0-dark 1.00E+06 1.00E+06 1.00E+06 0% 0.2 ml Candida albicans 120 min 0.05-0.1 1.00E+06 0 1.00E+06 100% Candida albicans 120 min 0.05-0.1 1.00E+06 0 1.00E+06 100% 0.2 ml Pseudomonas aeruginosa 120 min 0.05-0.1 1.00E+06 0 1.00E+06 100% Pseudomonas aeruginosa 120 min 0.05-0.1 1.00E+06 0 1.00E+06 100% 0.3 ml Enterococcus faecalis 4224 120 min 0.1-0.3 1.50E+08 767 not countable 99.99949% FN®: •PROVIDES HELPFUL PROTECTION TO CHILDREN AND OTHER PATIENTS ON CHEMOTHERAPY •PREVENTION OF INFFECTION OUTBREAKS Microorganism (FN2 Protocol #) Stapthylococcus aureus CCM 3953 1734/2010 H4 1474/2010 P4 1470/2010 P3 1473/2010 H4 1472/2010 H3 FN2 A FN2 B FN2 C Stapthylococcus aureus ATCC 33591 FN2-P1 FN2-P2 Staphylococcus aureus CCM 3953 prints on agar Stapthylococus aureus PP-FN2 tab 67 FN2 tab 61 FN2 DARK tab 42 START END Exposure UV UV Intensity concentration concentration time (min) mW/cm2 (CFU) (CFU) 0.2 ml 60 0.05-0.1 1.20E+08 100 60 0.05-0.1 1.20E+08 150 60 0.05-0.1 1.20E+08 100 60 0.05-0.1 1.20E+08 100 60 0.05-0.1 1.30E+08 100 60 0.05-0.1 3.45E+07 250 60 0.05-0.1 3.45E+07 250 ® 60 0.05-0.1 3.45E+07 250 Reference sample END concentration (CFU) Bacteria reduction on FN2 surface (%) 7.50E+05 7.50E+05 7.50E+05 7.50E+05 7.50E+05 1.10E+06 1.10E+06 1.10E+06 99.9999% 99.9999% 99.9999% 99.9999% 99.9999% 99.9993% 99.9993% 99.9993% NA NA 100% 100% LEGISLATION INnotEU) 34 countable 99.99998% FN : 0.35 ml • BIOCIDIDE EFFICACY 80 NA 1.00E+05 0 •80 NO CHEMISTRY-PHYSICAL EFFECT NA 1.00E+05 0 (2011 120 120 300 120 REMOVED 0.1-0.3 0.05-0.1 0.05-0.1 dark 0.3 ml FROM BIOCIDE 1.80E+08 0.1 ml 1.65E+09 1.00E+06 1.00E+06 34 250 1.00E+06 1.00E+04 1.00E+06 1.00E+06 99.999998% 99.975000% 0% MRSA is a serious hospital acquired infection, which is a form of the Staphylococcus bacterium resistant to the commonly used antibiotic methicillin. http://www.direct-healthcare.com/mrsa.htm FN Coatings are an excellent prevention of MRSA. No release of chemicals into the environment!!! Proportionally, 50% reduction of MRSA in the USA means: Saving life to 12,500 people Saving post operation problems to 250,000 people Reduction of economical losses ~ $ 4bn Hospital Acquired Infections cost the NHS around £1bn per annum, affect some 100,000 patients a year and is responsible for the deaths of around 5,000 patients annually in the UK. ……. alarming rate with some hospitals reporting secondary infection rates as high as 20%. FN® COATINGS – NO CHEMISTRY INVOLVED FN® COATINGS ARE EXTREMELY EFFICIENT IN “BURNING” MICROORGANISMS ON THEIR HIGHLY OXIDATIVE SURFACE THE PHOTOCATALYTIC ACTION IS AS STRONG AS USING POISONOUS CHEMICALS, WHILE IT IS PROVIDED SOLELY BY THE TiO2 PHYSICAL EFFECT OF PHOTOCATALYSIS, WHITH NO CHEMISTRY INVOLVED TiO2 IS COMPLETELY INERT, SAFE AND UNREGULATED COMPOUND WALLS AND CEILING PAINTED BY FN® COATINGS ARE A GREAT MICROBIAL PREVENTION AND A WAY, HOW TO CREATE CLEAN AND SANITARY ENVIRONMENT WITHOUT ANY CHEMICALS INVOLVED FN® COATINGS ARE INERT AND PERFECTLY COMPACTIBLE WITH ALL CHEMICALS AND DISINFECTING AGENTS. PRACTICAL INSTALLATION DIFFERS ONLY SLIGHTLY FROM REGULAR PAINTING GIC result CEILINGS – FN3® COATING UVA ACTIVATION LIGHT WALLS– FN2® COATING DAYLIGHT – MAIN SOURCE OF THE ACTIVATION ENERGY Internal Medicine Hospital SOFT UVA ACTIVATION LAMPS INSTALLED FOR DARK DAYS, NIGHT AND CRITICAL SITUATIONS SUCH AS INFECTION OUTBREAKS, ODOR PROBLEMS, ETC,… PHARMACY STORES USEFUL UNIVERSALLY Warehouses Fitness centers Dental clinique CHILDREN’S ONCOLOGY WAITING ROOMS Eye Clinique BREATH SAFE AIR YESTERDAY UNKNOWN TODAY AN OPTION TOMORROW A STANDARD