MCQs on stroke and TBI John O’Donovan MCQs 1-10 PTA GCS scores and TBI • Length of PTA is strongly associated with outcome from mild traumatic brain injury. • PTA ends when anterograde amnesia ends. • PTA in excess of 2 hours suggests a severe injury • PTA includes retrograde amnesia from event • PTA can be measured in PVS via CSF clusterin and S100 beta • GCS of 13 should make a good recovery • GCS of 8 at 3 hours with PTA of 13 days suggests a severe head injury. • Accurate GCS in ICU is frequently impossible. • GCS of 3 is equivalent to being dead. • GCS whilst intoxicated may be falsely elevated. MCQs 10-20 In SAH • 50% of patients die. • Hydrocephalus may be a complication in 10% • Psychiatric complications from an PICA aneurysm may include a Wernicke-Korsakoff state. • Depression is commoner post event then in lacunar stroke • AVMs may be associated with psychosis Depression post stroke • Has a prevalence of up to 79% at 3/12 • Responds best to serotinergic medication • Is reduced by anosagnosia • Is strongly associated with lesion location • Can be prevented by prophylactic treatment with SSRIs MCQS 20-30 RISK FACTORS FOR TBI • A 21 woman has a risk approximately half that of a 21 man • Low IQ is associated with TBI • Prior head injury is the most significant known risk factor . • High levels of testosteronne • Platelet MAO levels are associated with risks for TBI Mania post stroke • Is more common then psychosis. • Is associated with non dominant lesions. • Jung might have considered this as a manic defence. • Responds well to lithium • Can arise from symptomatic seizures from cortical infarcts. MCQs 30-40 In diffuse TBi The catastrophic reaction is • A grade 1 axon lesion is associated with PTA of 6 days. • A grade 4 axonal lesion will always die. • It’s the rapid stopping that causes the problem. • CSF is not always helpful as a cushion. • Petechial haemorrhages are common and visible on CT 74% of the time. • Associated with cheating on one’s spouse. • Minor frustration being unable to perform complex and difficult tasks. • Associated with bilateral frontal damage. • May be helped by SSRIs • Generally something which always improves over time and acceptance of disability MCQs 40-50 Match them up • CADASIL • Moya Moya • PTA of 15 days • Head of caudate lesion • Leucoaraiosis/multiple lacunar strokes Match them up • Rising sun • DTI • Saying and doing very little • Photophobia and flashing lights • Vascular depression MCQs 40-50 Match them up • PVS • Dominant MCA stroke • Anterograde amnesia • Blind on a cardiology ward • CO poisoning • falling over in McDonalds and banging your head Match them up • Wearing wigs • Catalytic converters • “it’s curtains for you” • Zolpidem • Psychic gaze apraxia