Europass
Curriculum Vitae
Personal information
First name(s) / Surname(s)
Address(es)
Francesca Romana Patacchioli
Department of Physiology & Pharmacology “V. Erspamer”
Sapienza – University of Rome –
Piazza Aldo Moro 5
00185 Roma
Telephone(s)
Int.+ 39 0649912506
Mobile:
Int.+ 39 3383358038
Fax(es)
E-mail
Nationality
Date of birth
Francesca.patacchioli@uniroma1.it
Italian
December 29th, 1950
Gender
Female
Occupational field
BIO 14
Work experience
Past positions held in the University
Present position held in the University
Main research activities and
responsibilities
Page 1/5 - Curriculum vitae of
Prof Francesca Romana Patacchioli
• 1980-2004: Assistant Professor Researcher Department of Physiology & Pharmacology, Sapienza
University School of Medicine, Rome
Associate Professor of Pharmacology
Since 1976, Prof. PATACCHIOLI is involved in the study of the hypothalamus-pituitary-adrenal (HPA)
activity in rodents and humans. In the last 10 years she set up and validated a new methodology for
measuring stress-related hormones in saliva, which avoid the stressful event of venipuncture. She
studies the HPA activity in different physiopathological conditions: aging, menopause, irritable bowel
syndrome, amiotrophic lateral sclerosis, acute and chronic stress, focusing on the question whether
steroid hormones (exogenous and/or endogenous) induced neurodegeneration and/or
neuroprotection.
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Present didactic activity
Teaching Pharmacology in the Faculty of Medicine “S Andrea Hospital” (2 CFU; Coordinator 3rd
Year; Active Member and Supply President of Examining Board
Teaching Pharmacology in the Health Profession Courses of:
Faculty of Nurses “S Andrea Hospital” (2 CFU; Coordinator of the Course; President of Examining
Board); Faculty of Physioterapy “S Andrea Hospital” (0.5 CFU; Coordinator of the Course; President
of Examining Board;
Faculty of Podology “S Andrea Hospital” (1 CFU; Coordinator of the Course; President of Examining
Board);
Faculty of Obstetrics “S Andrea Hospital” (1 CFU; Coordinator of the Course; President of
Examining Board);
Faculty of Laboratory Tecniques “S Andrea Hospital” (1 CFU; Coordinator of the Course; President
of Examining Board);
Faculty of Environmental and working place prevention Tecniques “S Andrea Hospital” (1.5 CFU;
Coordinator of the Course; President of Examining Board);
Faculty of Orthopedic Tecniques “S Andrea Hospital” (2 CFU; Coordinator of the Course; President
of Examining Board).
Education and training MD and Biologist
Personal skills and
competences
Mother tongue(s)
Other language(s)
Self-assessment
Italian
English and French
Understanding
Speaking
Spoken interaction
Writing
European level (*)
Listening
Reading
Spoken production
English
French
C1
C1
C1
C1
C1
C1
C1
B2
C1
B2
(*) Common European Framework of Reference for Languages
Additional information
Receiving (students)
Page 2/5 - Curriculum vitae of
Prof Francesca Romana Patacchioli
Tuesday and Thursday: 8:00-10:00 and 15:00-17:00; Monday and Wedsneday: 1012
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© European Union, 2004-2010 24082010
30 Peer reviewed publications (a selection of last 15 years)
1
Ghiciuc C.M., Dima-Cozma C.L., Pasquali V., Renzi P., Lupusoru C.E. and Patacchioli F.R. (2011)
Awakening responses and diurnal fluctuations of salivary cortisol, DHEA-S and alpha-amylase in healthy male subjects.
Neuroendocrinol Lett, 32(4):475-480. IF 1.621
2
Simeoni S., Biselli R., D’Amelio R., Rocca B., Lattanzio S., Mucci L., Davì G. and Patacchioli F.R. (2011)
Stress-induced salivary cortisol secretion during hypobaric-hypoxia challenge and in vivo urinary thromboxane
production in healthy male subjects. Stress, 14:282-289.
IF 3.205
3
Simeoni S., Colantuono M., Suma V., Perrone G. and Patacchioli F.R. (2009)
Performance during mental stress in menopausal women: salivary cortisol in the Stroop Color Word Test (CWT). Behav
Pharmacol, Vol. 20: Special Issue 1, S68.
IF 2.530
4
Martelletti P., Farinelli I., Coloprisco G. and Patacchioli F.R. (2007)
Role of NSAIDs in acute treatment of headache. Drug Dev Res, 68:276-281.
IF 1.109
5
Piane M, Lulli P, Farinelli I, Simeoni S, De Filippis S, Patacchioli F.R. and Martelletti P. (2007)
Genetics of migraine and pharmacogenomics: Some considerations. J Headache Pain, 8(6):334-339.
IF 2.015
6
Silvestrini G., Ballanti P., Leopizzi M., Gualtieri N., Sardella D, Monnazzi P., Simeoni S., Sebastiani M., Bonucci
E., and Patacchioli F.R. (2007)
Effects of the administration of corticosterone, parathyroid hormone, or both, and of their withdrawal, on rat bone and
cartilage histomorphometric parameters, and on osteoprotegerin and RANKL mRNA expression and proteins. J Mol
Histol, 38(3): 215-226.
IF 1.202
7
Patacchioli F.R., Simeoni S. and Martelletti P. (2007)
HPA axis derangement in chronic migraine. Effect of botulinum toxin type A. J Headache Pain, 8: S15.
IF 2.015
8
Patacchioli F.R. e P. Martelletti (2006)
Neuroendocrine derangement in chronic migraine: fact or fiction? Headache, 46(8): 1309-1310.
IF 2.642
9
Patacchioli F.R. Monnazzi P., Simeoni S., De Filippis S., Salvatori E., Coloprisco G. and P. Martelletti (2006)
Salivary cortisol, dehydroepiandrosterone-sulphate (DHEA-S) and testosterone in women with chronic migraine. J
Headache Pain, 7(2): 90-4.
IF 2.015
10
Patacchioli F.R., Simeoni S., Monnazzi P., Pace M., Capri O., Perrone G. (2006)
Menopause, mild psychological stress and salivary cortisol: influence of long-term hormone-replacement-theraphy
(HRT). Maturitas, 55(2): 150-155.
IF 2.286
11
Silvestrini G., Ballanti P., Patacchioli F.R., Leopizzi M., Gualtieri N., Monnazzi P., Tremante E., Sardella D.,
Bonucci E. (2005)
Detection of osteoprotegerin (OPG) and its ligand (RANKL) mRNA and protein in femur and tibia of rat.
J Mol Histol, 36: 59-67.
IF 1.202
12
Buttarelli F.R., Patacchioli F.R., G.Palladini, E. Brunetti, F.E. Pontieri (2004)
Neuropharmacology of cannabinoid system: from basic science to clinical applications.
Curr Neuropharmacol, 2: 1-7.
IF 2.783
13
Patacchioli F.R., Monnazzi P., Scontrini A., Tremante E., Caridi I., Brunetti E. , Buttarelli F.R., Pontieri F.E., (2003)
Page 3/5 - Curriculum vitae of
Prof Francesca Romana Patacchioli
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© European Union, 2004-2010 24082010
Adrenal dysregulation in amyotrophic lateral sclerosis. J Endocrinol Invest, 26:23-25.
IF 1.476
14
Monnazzi P., Leri O., Guizzardi L., Mattioli D., Patacchioli F.R (2002)
Anti-stress effect of yoga-type breathing: modification of salivary cortisol, heart rate and blood pressure following a stepclimbing exercise. Stress & Health, 18:195-200.
IF 0.789
15
Giubilei F., Patacchioli F.R. , Antonini G., Sepe Monti M., Tisei P., Bastianello S., Monnazzi P., Angelucci L (2001)
Altered circadian cortisol secretion in Alzheimer's disease. Clinical and neuroradiological aspects.
J Neurosci Res, 66: 262-265.
IF 2.958
16
Mocetti P., Silvestrini G., Ballanti P., Patacchioli F.R., Di Grezia R., Angelucci L. and Bonucci E. (2001)
Bcl-2 and Bax expression in cartilage and bone cells after high dose corticosterone treatment in rats
Tissue Cell, 33(1):1-7.
IF 1.698
17
Patacchioli F.R., Angelucci L., Dell'Erba G., Monnazzi P. and Leri O. (2001)
Actual stress, Psychopathology and Salivary Cortisol Levels in the Irritable Bowel Syndrome (IBS)
J Endocrinol Invest, 24:173-177.
IF 1.476
18
Pontieri E.F., Monnazzi P., Scontrini A., Buttarelli F.R. and Patacchioli F.R. (2001)
Behavioral sensitization to WIN55212.2 in rats pretreated with heroin. Brain Res, 13;898(1):178-80.
IF 2.623
19
Pontieri E.F., Monnazzi P., Scontrini A., Buttarelli F.R. and Patacchioli F.R. (2001)
Behavioral sensitization to heroin by cannabinoid pretreatment in the rat. Eur J Pharmacol, 15;421(3):1-3. IF 2.737
20
Catalani A., Casolini P., Scaccianoce S., Patacchioli F.R., Spinozzi P., and Angelucci L. (2000)
Maternal Corticosterone during lactation permanently affects brain corticosteroid receptors, stress response and
behaviour in rat progeny. Neuroscience, 100: 313-325. IF 3.215
21
Silvestrini G., Ballanti P., Mocetti P., Di Grezia R., Wedard B.M., Patacchioli F.R., Angelucci L. and Bonucci E.
(2000)
Evaluation of apoptosis and glucocorticoid receptor in cartilage growth plate and metaphyseal bone cells of rats after
short-term, high dose administration of corticosterone and after recovery. Bone, 26:33-62.
IF 4.601
22
Patacchioli F.R., Angelucci L., Casolini P., Bottone A., Borboni P., Lauro R. and Marlier N.J.L. (1998)
Corticosterone treatment differentially affects adrenocorticoid receptors expression and binding in the hippocampus and
spinal cord of the rat. J Mol Neurosci, 11:95-103.
IF 2.922
23
Patacchioli F.R., Pontieri F., Orzi F., Di Grezia R. and Angelucci L. (1998)
Increased motor response to cocaine administration following recovery from chronic corticosterone treatment in the rat.
Eur Neuropsychopharm, 8:43-46. IF 4.201
24
Marlier L.NJL., Patacchioli F.R., Porzio O., Chiusaroli R., Borboni P., Lauro R. and Angelucci L. (1997)
Distribution od adrenocorticoid receptors in the rat CNS measured by competitive PCR and cytosolic binding. J Mol
Neurosci, 9:1-12. IF 2.922
25
Patacchioli F.R., Pontieri F.E., Di Grezia R., Colangelo V., Angelucci L. and Orzi F. (1997)
Increased functional response to cocaine challenge following recovery from chronic corticosterone in the rat. Eur J
Pharmacol, 336:159-162. IF 2.737
26
Sancesario G., Pietroiusti A., Cestaro B., Fusco F..R., Magrini A., Patacchioli F.R., Franceschelli L. and Galante
A. (1997)
Page 4/5 - Curriculum vitae of
Prof Francesca Romana Patacchioli
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© European Union, 2004-2010 24082010
Mild brain ischemia increases cerebral lipid peroxidation and activates leukocytes in the paripheral blood rats. Funct
Neurol, XII (5):283-291.
IF 1.481
27
Cabib S., Castellano C., Patacchioli F.R., Cigliana G., Angelucci L. and Puglisi-Allegra S. (1996)
Opposite strain-dependent effects of post-training corticosterone on memory storage in mice: role of dopamine. Brain
Res, 729: 110-118.
IF 2.623
28
Figà-Talamanca I., Cini C., Varricchio G.C., Dondero F., Gandini L., Lenzi A., Lombardo F., Angelucci L., Di
Grezia R. and Patacchioli F.R. (1996)
Effects of prolonged autovehicle driving on male reproductive function: a study among taxi drivers.
Am J Ind Med, 30:750-758.
IF 1.750
29
Marlier L. NJL., Patacchioli F.R., Porzio O., Bottone A., Di Grezia R., Borboni P., Lauro R. and Angelucci L. (1996)
Differential regulation of adrenocorticoid receptors in the hippocampus and spinal cord of adrenalectomized rats. J
Neurosci Res, 43:526-534.
IF 2.958
30
Patacchioli F.R., Di Grezia R. and Angelucci L. (1996)
Arginine-Aspartate and Haloperidol-induced neurobehavioral effects in the rat. Eur J Pharmacol, 299:29-32. IF 2.737
BOOK CHAPTERS
Badria F.A., Abou-seif M., Ossama M., Ahmed A.F., Simeoni S. and Patacchioli F.R. (2009): Hypoglycemic effect and
mechanism of action of Balanites Aegyptiaca on streptozotocin-induced diabetic rats.
In: Adverse effects of pharmacologic active substances: from bench to bedside. Editors Lupusoru C.E., Tartau L., Printed
in Junimea (Romania) 17-30.
ISBN: 978-973-37-1351-7
2.
Badria F.A., Houssen M.A., Mesbah A., Ragab A., Othman G., El-Samanoudy A.Z., Fathy A., Lupusoru C.E., Simeoni S.
and Patacchioli F.R. (2009): Complementary theraphy for bronchial asthma: natural anti-inflammatory and leukotriene
inhibitor.
In: New pathophysiological challenges and pharmacological approaches. Editors Lupusoru C.E., Ghiciuc C.M., Tartau L.,
Printed in Junimea (Romania), 1-13.
ISBN: 978-973-37-1428-6
3.
Dima-Cozma C., Pandele G.I., Simeoni S., and Patacchioli F.R. (2009): Hormone replacement therapy: between benefits
and side effects.
In: New pathophysiological challenges and pharmacological approaches. Editors Lupusoru C.E., Ghiciuc C.M., Tartau L.,
Printed in Junimea (Romania), 87-94.
ISBN: 978-973-37-1428-6
Page 5/5 - Curriculum vitae of
Prof Francesca Romana Patacchioli
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© European Union, 2004-2010 24082010