Parasitology Continue Helminthology Platyhelminthes (Flat worms) Trematoda (Flukes) Ceastoda (Tape worms) Nematohelminthes (Round worms) Nematoda Class Cestoda (Tape Worms) General Characters Ribbon or tape shaped. Adult worm composed of:a. Rounded scolex with appendages for attachment (e.g. Suckers or hooked rostella). b. Neck (region of growth). c. Strobillum (composed of 3- 4000 segments [proglottide]). Length varies between 3mm-10m. Continue All cestodes are hermaphrodite (Each segment contains male & female reproductive system). No body cavity. No digestive tract. No vascular system. Continue Continue Continue Habitat: a. Adult worms live in small intestine of their definitive hosts. b. Larval stage found in intermediate hosts tissues. Eggs are diagnostic stage (Spherical, with shell embryonic membranes for embryo protection; the embryo [onchosphere] carries 6 elongated hooks [hexacanth]) Replication is either by self-fertilization or by cross fertilization. Usually the presence of adult worms in the host intestine does not produce serious symptoms, but severe and sometimes fatal symptoms may occur due to presence of the larval stage in the host tissues (e.g. Tainea solium & Echinoccus granulosus). Trematoda 2nd I.H I.S. Animal Cercaria 1st I.H (R) D.H D.S Cestoda I.S. D.H I.H. D.S In this course we study: Taenia solium & Taenia saginata Hymenolepis nana & Hymenolepis diminuta Echinococcus granulosus. Taenia solium & Taenia saginata Taenia solium Taenia saginata Definition:- Pork tape worm Beef tape worm Distribution: World wide World wide Name: • Depends on the • Depends on the access of pigs to access of cattle to human feces and to human feces. consumption of raw & undercooked pork . • More endemic in Asia, South Africa and East Europe. Taenia solium Taenia saginata Disease: Habitat: Definitive host: Intermediate host: Taenia solium Diagnostic stage: Infective stage: Mode of infection: Treatment: Prevention: Taenia saginata Taeniasis Presence of the adult worm in small intestine of human, symptoms are not significant and thought to be psychic due to vision of active proglottides in stool, these symptoms may be abdominal discomfort and intestinal irritation. Cysticercosis larvae development occurs in 2 months to give a fluid filled bladder with armed scolex [a cysticercus]. T. solium eggs ingested by human hatch in the intestine, penetrate mucosa & enter blood circulation resident in liver, skeletal muscles, brain or eye. Usually no immune response as the larvae are alive but when they die, the larvae are classified after an inflammatory response and symptoms begin to appear. • In muscles: Fever, swelling, atrophy & fibrosis. • In brain: Symptoms resembling brain tumors, epilepsy, ataxic gait or mental confusion (Neurocysticerosis). • In eye orbit: In anterior or posterior chambers affect eye position, decrease visual acuity, retinal edema and haemorrhage. • Subcutaneous: Palpated tumors. Adult worm This slide shows the gravid segment ; contains male & female reproductive system). [1] Gravid segment [2] Mature segment Differences between T. solium &T. saginata Scolex: Taenia solium Taenia saginata Hooked with a rostellum of double hooked crown Hooked scolex is absent Proglottides: In T. solium are shorter than those of T. saginata Uterine branches of gravid segments: Are lower in number in T. solium than that of T.saginata Hooked scolex Sucker [1] [2] [1] [2] T. solium has 7 to 13 branches. T. saginata has 15 to 20 branches. ? Diagnostic Stage • Taenia egg Taenia saginata & Taenia solium. * Appears in stool. * Egg contains oncosphere embryo with 6 hooklets (hexacanth embryo).