Nutrition in Dyslipidemia Yenni Zuhairini Nutrition Department Lipid metabolism disorders marked by an increase or decrease in plasma lipid fractions DYSLIPIDEMIA Risk for CHD incidence Blood lipid profile – High total cholesterol – High LDL cholesterol – High triglyceride – With or without low HDL CHOLESTEROL Principles of nutritional therapy for lowering cholesterol • Reduce consumption of dietary cholesterol • Inhibit the production of cholesterol in the body • Inhibits absorption and increase excretion of cholesterol by the intestine Reduce consumption of dietary cholesterol • By avoiding high cholesterol foods, such as: – Brain, marrow, organ meats – Egg yolk (wheat) – Cheese, butter (wheat) – Animal skin (kikil, krecek) – Shrimp (shrimp paste, terasi) The Content of Cholesterol per 100 g of Food Food stuff Brain Egg yolk Egg Kidney Liver Pancreas Tripe, animal stomach Cholesterol (mg) 2200 1600 548 370 300 250 150 The Content of Cholesterol per 100 g of Food Food stuff Cholesterol (mg) Lobster 150 Shrimp 150 Lard 95 Cheese 79 Butter 219 Whole milk 14 Vegetable cooking oil 0 Reduce Consumption Of Dietary Cholesterol • Cholesterol intake <300 mg / day can be achieved with the menu without high cholesterol foods • Cholesterol intake <200 mg / day can be achieved with the menu without animal foods, except lean meat or fish weighing 200 g / day Exogenous Pathway Food particles Bile Acids Liver Intestines Chylomicrons Chylomicro n Remnants Bloodstream Breakdown of Triglyceride Free Fatty Acids Endogenous Pathway LDL HDL Liver Body Tissues Bloodstream VLDL Breakdown of Triglyceride Free Fatty Acids IDL Inhibit the manufacture of cholesterol in the body Avoid excess of energy in body Lose weight for people with excess body fat Classification of weight status according to BMI in Asian Adults Classification BMI (kg/m2) Comorbidities Underweight < 18.5 Normal range 18.5 – 22.9 Low (but risk of other clinical problems increased) Average Overweight At Risk > 23.0 23.0 – 24.9 Increased Obese class I 25.0 – 29.9 Obese class II > 30.0 Moderate Severe Source: WHO/IASO/IOTF (2000) BMI=(Body weight in kg) /(Body height in cm)2 Increase the consumption of fiber, especially water-soluble (pectin, guar gum, gum) which are abundant in : Increase excretion and inhibiting the absorption of cholesterol – Apple, orange, guava, pear – Passion fruit, papaya, dll – Red bean, soy, tofu, tempe, etc. Food Menu for lowering LDL cholesterol level • Low cholesterol <200 mg / day • Low fat (+ 30% of calories) • lipid composition – SFA <7% of total calories – PUFA to 10% of total calories – MUFA and 20% of total calories – Avoid trans fat Raising HDL cholesterol Research shows that: • Weight loss in obese people • Stop smoking in smokers • More active in the less active will lower LDL levels and increase plasma HDL levels Normal HDL cholesterol Regular exercise or eat enough fiber TRIGLYCERIDE Terapi nutrisi untuk menurunkan trigliserida • Mengurangi konsumsi trigliserida (lemak) • Mengurangi pembuatan trigliserida oleh tubuh • Menambah pengunaan trigliserida oleh tubuh Reduce consumption of triglyceride • Avoid fatty meats: satay, gule, oxtail soup, stew legs, pig, etc. • Fried thin shape food, such as dendeng, crackers, chips, etc. Reducing triglyceride synthesis by the body • By creating energy deficit, that are: – Reduce consumption of foods – Raising energy use – Reduce consumption of foods for only the excessive food If excess carbohydrates, reduce simple carbohydrates (starch and sugar) so that fiber is not reduced When excess fat, reduce animal fats so that the ratio of polyunsaturated / saturated fatty acid increases and dietary cholesterol intake decreases Increasing use of triglycerides • Changing inactivity becomes more active • Doing aerobic exercise of moderate intensity and long duration such as walking TERIMA KASIH