Nuclear Medicine division status

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Nuclear Medicine division status

Jean-Michel Poutissou

7 th April 2011

Response to last year’s report

• Formal screening of new projects

• MHESA project status

• CCM status

• Expansion of wet laboratory space

• New recruitment

• Graduate students

• Solid target

• New imaging detectors

• MDS Nordion collaboration

November 29

th

retreat

• 15 months NRCan NISP grant for cyclotron production of 99m Tc received : Tight delivery deadlines. (March 2012)

• NSERC/CIHR grant ongoing (LS96) linked to the above.

• MHESA new radiochemistry laboratory ( Joint project with Nordion) finally on track to be done soon ( TRIUMF`s share in the NRC budget to be expended by March 2011)

• GMP lab to be operational in December

• Radiochemistry research projects

NUMED FY 2011-12 Goals

• 1) deliver on the NRCan project milestones

• 2) Deliver Tracers to our best partners like

PPRC,PET centre, BCCA, UBC faculties

,Nordion, GE,..

We need:

• MHESA laboratory completion and operation

• GMP lab Operation

Other goals

• Centre Comparative Medicine

– New MicroPet /Spec scanner (CFI-Vesna)

– Design of new pipeline connection to CCM

• Detector development:

– New MicroPet/MRI scanner F.Retiere

CFI proposal ( U.Manitoba/UBC/TRIUMF)

– New “low” cost PET scanner development (

TRIUMF/BCCA) by Fabrice Retiere

Other projects under consideration

• Second CDR grant with Nordion

• Grant application with Genome BC

• Canadian Molecular Imaging Network centre of excellence proposal to be submit by August

JMP

Major Tasks

Milestones

Detailled design

Tender & award contract

Construction

Hot cells delivery

Install

Commissioning

GMP lab 005

GMP lab 005 operation

GMP lab 007 upgrade ??

Funding approved

Team organized

Target development and testing

Report to NRCan

Cyclotron proposal

.New building/TR19 relocation

NU-MED Plan (2010-2015)

November 29, 2010

2010

A J O J

2011

A J O J

2012

A J O J

2013

A J O

2014

J A J O J

2015

A

)

NRU restart ommissioningl

Legend:

Research

Infrastructure construction

Science

• CFI proposal ( MPET/SPEct/ct

• Icfi PROPOSAL (MULTI MODAL FACILITY)

• piPELINE

NSERC/CIHR

Target Chemist

Deputy Division Head

Core Programs

M. Adam

Principal Investigator

Project Manager

NRCan

Nuclear Medicine

J.M. Poutissou

Special Advisor

T. Ruth

Deputy Division Head

New Programs

P.Schaffer

NRCan Partners

SeniorTarget

Scientist

New Infrastructure

(P&S)

Targets/Medical

Isotope Production –

Lead Scientist (BAE)

Cyclotron-Ops

Target Chemist

SeniorTarget

Scientist

Target

Engineer

New Tracers Radiochemistry – Lead

Scientist (BAE)

Electromechanical

Engineer

Electromechanical

Engineer

Target

Engineer

NRCan NISP project

New infrastructure

GMP laboratory RCA005 upgrade:

– 3 new hot cells ( Comecer)

– 3 new chemistry boxes

– New ventilation strategy

– Clean room environment

GMP lab/personnel

MHESA laboratory

Centre for Comparative Medicine

• Construction on going

• Occupancy ( early 2012)

• CFI proposal for a Spect/Pet micro scanner by V.Sossi and P.Schaffer.

Major concern with PETA activist group

New policy on disclosure of our LSPEC proposals and reports

Hiring plan

• One extra Scientist ( radiochemist)

• One professional ( MHESA lab manager)

• Mike Adam will be replaced when he retires.

• Several additions to the target group will be absorbed when the NRCan project terminates

( new soft funding or NRC bridge funding)

Students/ Postdocs

• NRCan NISP project:

• TOM MORLEY, PDF

• PPRC/UBC PET Centre collaboration and the Good Manufacturing Practice Laboratory (GMP) upgrade:

• G. TOPPING, PHD STUDENT (LS 94)

• 1 MSc STUDENT (VESNA)

• 3 PHD STUDENTS ( VESNA)

• NORDION/TRIUMF collaboration:

• ESTER BOROS, PHD STUDENT

• ERIC PRICE, PHD STUDENT

• CATERINA RAMOGIDA, PHD STUDENT

• JAQUELINE CAWTHRAY, PDF

• LISA MURPHY, PDF

Students/Postdocs

• BCCA-TRIUMF collaboration:

• NONE AT THIS TIME

• GE Healthcare Collaboration:

• HUA YANG, PDF

• CIHR/GENOME BC proposal (OLIGONUCLEOTIDES, MICRO-FLUIDICS):

• JAMES INKSTER, PHD STUDENT

• KATE LIU, CO-OP STUDENT

• SAMAR HAROUN, PHD STUDENT

• ZARA SANAI, PHD STUDENT

• YING LI, PHD STUDENT

• M. POURSHIASIAN, PHD STUDENT

• Collaboration with UBC’s Centre for Comparative Medicine (CCM):

• TBA

• MINet collaboration:

• TBA

Policy for the SAP-EEC,MMS-EEC and LSPEC

• In order to align TRIUMF policies on openness with other laboratories around the world, this document outlines in broad terms our new policies. Below EEC refers to all three committees.

• 1) All proposals submitted to TRIUMF will be available for view on the TRIUMF internal WEB in their entirety after review and if approved by the EEC.

– a. Only the title, author list, status, and short abstract (< 300 words) will be displayed on the public web pages.

– b. The EEC reports (and comments) are internal TRIUMF documents and will only be displayed on the internal TRIUMF web site. The full EEC report will be made available to the appropriate external funding committees.

– c. Proposals with private sector partners should follow Non Disclosure Agreements.(NDA)

• 2) Presentations to the EECs are open to everyone. Slides are available to the committee only.

• 3) Review committee members will treat the content of proposals as confidential.

• 4) Requests for information on proposals from outside the TRIUMF community will be granted only by the authors in consultation with TRIUMF communications.

• 5) Within 60 days of receiving beam time the spokesperson will provide to the Science Division for posting, on the public WEB pages, a short summary (< 300 words) of the experiment results. The summary of results will be used in the annual report. Details are disclosed at the discretion of the spokesperson.

• 6) The interpretation and application of this policy is the responsibility of the respective Division

Head.

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