Progress on SIAs and MCV2 introduction in India Dr. Pradeep Haldar Deputy Commissioner (Immunization) Ministry of Health & Family Welfare Government of India Washington DC 18-19 Sep 12 Measles Vaccination in India • Measles vaccination was introduced under the National Universal Immunization Programme (UIP) in 1985 given to children at 9-12 months age • Line listing of measles outbreak cases started in 2005 in selected states. • In 2010, Government of India introduce 2nd dose of Measles under UIP through a two prong strategy. 2nd dose of Measles vaccine: State specific delivery strategies National Technical Advisory Group on Immunization recommended second dose of measles vaccine for all states through state specific delivery strategies. • 14 states with MCV1 <80%: Measles SIA (9 month to <10 years) followed 6 month later by MCV2 under RI • 21 states with MCV1 > 80%: MCV2 under RI at 16 to 24 months of age MCV2: Coverage of Measles containing vaccine 2nd dose per DLHS-3; CES-06 for Nagaland Measles second opportunity – India 3 MCUP: Basic considerations All children in target age-group (9 mo-<10 years) to be vaccinated – Irrespective of previous doses of measles vaccine received – Irrespective of prior history of measles disease In general, this age group constitutes around 18-25% of the total population – Target: ~135 million children – Expected coverage: More than 90% (evaluated coverage) Massive public health undertaking with an injectable vaccine Both safety and high coverage are critical MOH&FW decided to take a phased approach Measles second opportunity – India 4 MCUP: Basic operational strategy All immunizations from static posts (no HTH immunization) Regular routine immunization sessions will be conducted without interruption – – Two regular routine immunization clinics per week Measles catch-up campaign in remaining four days Average Campaign duration: 3 weeks = 12 working days – 1st week: School based campaign (for 5-10 year children) – 2nd & 3rd weeks: Community based campaign for non-school going children or children missed during school week Training – – – Only trained persons (ANMs) will work as vaccinators All ASHA/ AWW will be trained for beneficiary listing and Inter-personal communication Doctors (including clinicians in pvt. sector) have been trained in managing rare adverse events, if any Measles second opportunity – India 5 MCUP: session sites and teams Types of session sites – Session sites at Educational Institutes. – Outreach site (regular RI sites and additional sites in village/urban mohalla) – Mobile/Special team – Facility based session site Team composition – – – – 1-2 Auxiliary Nurse Midwife (ANMs) ASHA (Accredited Social Health Activist) AWW (Anganwadi Worker) Volunteer Measles second opportunity – India 6 Measles second opportunity – India 7 Overview of Measles SIA JAMM U & KAS HM IR HI MAC H AL PR AD ES H PU NJA B CH AN D IGA RH UT T AR AK HA N D HA RY AN A DE LH I AR UN AC H AL PR . SIKK IM UT T AR P RA DE SH RA JAST H AN ASSA M Target population: ~ 135 million children 9 months – 10 years of age 365 districts in 14 states NA GAL AN D BIH AR MEG HA LAY A MAN IP UR JHA RK HA N D GUJ AR AT MAD H YA PR AD ESH Phase 1, 45 districts covered (~ 13 million) TR IP UR A W EST B EN GAL MIZ OR AM Phase 2, 152 districts covered (~ 40 million CH H AT T ISG AR H ORI SSA DA MAN & D IU D& N HA VEL I Phase 3, 167 districts planned (~ 81 million) MAH AR A SH TR A AN DH R A P RA D ESH KAR N AT AKA PON D IC HE RR Y GOA A&N IS LAN D S LAK SH AD W EEP TA MIL N AD U KER AL A Phase 1 in 2010 -11; Phase 2 in 2011-12; Phase 3 in 2012-13 Starting Sep 12 Measles second opportunity – India 8 Measles catch-up campaign (MCUP) Measles second opportunity – India 9 Measles second opportunity – India 10 Measles SIA phasing plan, India Total number of Districts Districts covered in Phase 1 Districts covered in Phase 2 ARUNACHAL PR. 16 1 15 ASSAM 26 1 25 BIHAR 38 5 15 CHHATTISGARH 18 9 9 GUJARAT 32 5 5 HARYANA 21 5 16 JHARKHAND 24 5 19 MADHYA PRADESH 50 5 13 MANIPUR 9 1 8 MEGHALAYA 7 1 6 NAGALAND 11 1 10 RAJASTHAN 33 5 5 4 1 3 State TRIPURA UTTAR PRADESH 75 Number of Districts for Phase 3 18 22 32 23 3 72 Total 364 45 152 167 Target Population ~134,000,000 13,845,686 40,167,580 ~81,000,000 12,076,836 (87.2%) 36,102,564 (89.9%) Coverage (% Achieved) Measles second opportunity – India 11 Coverage achieved: Administrative and RCA monitoring (MCUP Phase 1 & 2) 48,179,400 of 54,013,266 vaccinated (89.2%) 98 of 197 districts with >= 90% coverage Number of Children monitored 2465 22438 287758 31462 49174 132343 140880 181299 Measles second opportunity – India 12 160 3308 2175 41846 3280 27867 Campaign awareness & source of information (in %) 100 94.9 90 83.7 80 70 60 Vast majority of those monitored were aware of the campaign Session sites with visible IEC material – 82.6% Sites where social mobilization was being done by house visits – 88.3% 50 40 30 16.4 20 7.7 10 0 Awarness for the campaign Health worker/ ASHA/AWW Teachers Family members/ Community Measles second opportunity – India N= 638,660 children monitored 13 5.3 Newspaper/ Poster/ Banner 1.4 TV/Radio/Miking Reasons for missing vaccination during Measles catch-up campaigns-India (RCA) Social mobilisation Operational 52% 44% Others Social mobilisation includes •Parents didn’t know of campaigns, •Didn’t know about Place/Date, •Didn't give Importance •Fear of Injection & AEFI 4% (N – 87,197) Operational • No vaccine/logistics • No vaccinator •Site too far, long queue Others •Family travelling, sick child, •Gone to School etc Measles second opportunity – India N - Total No of Unvaccinated children verified by RCA – (87,197) 14 Measles second opportunity – India 15 Measles SIA timeline (3rd phase) MADHYA PRADESH Period of campaign Sep-12 Oct-12 Nov-12 Dec-12 Jan-13 GUJARAT RAJASTHAN BIHAR UTTAR PRADESH No. of Districts 12 (17 Sep) 22 (13 Sep) 9 (17 Sep) 7 8 5 8 6 18 22 16 11 23 Feb -13 Mar -13 Apr-13 Measles second opportunity – India 16 Partner support in measles 2nd dose Key partners : WHO and UNICEF Areas of Support: Support to steering committee and operational groups at national, state and district level. Development of strategic guidelines, tools and IEC prototypes Program implementation support to states incl. capacity building and supportive supervision Media sensitization at national, state and district levels Surveillance in 11 states Strengthening cold chain through assessment, supply and capacity building Micro-planning, training, and social mobilization using polio resources (SMOs and SMNet) Campaign monitoring Data analysis and dissemination incl. quarterly newsletter Measles second opportunity – India 17 Summary of measles 2nd dose Measles 2nd dose under RI at 16-24 months introduced in 21 States/UTs in 2010 Measles SIA completed in 197 districts in 14 states with coverage of 90% in two phases. In 9 states out of 14 completed measles SIA in all districts. 2nd dose of measles under RI started 6 month after measles SIA Remaining 167 districts in 5 states planned/ on going measles SIA during 2012-13 with target of 81 million children (UP, MP, BI, RAJ, GUJ) Case based surveillance, expansion of laboratory network, Rubella vaccination refer to sub committee of NTAGI on strategy ie vaccinate children or adolescent group or both. MEASLES 2ND DOSE WILL BE UNIVERASLIZED IN THE ENTIRE COUNTRY BY 2014 Measles second opportunity – India 18 Impact on measles transmission [Data as on August 2012] Measles second opportunity – India 19 SIA and RI Plans Line listing of measles surveillance States with MCV2 through MCUP Surveillance initiated 2006 States with MCV2 in RI 2007 2009 2010 2011 2012* MCUP: Measles catch-up campaign * State workshops conducted in Haryana, March 2012 MCV2: Measles containing vaccine, 2nd dose Measles second opportunity – India 20 Measles cases and outbreaks in districts completed catch-up campaigns and lab supported measles surveillance before and after start of MCUP Pre-MCUP Surveillance data from MCUP districts* State MCUP Phase & (No. of districts covered) Reference period (From) MM-YYYY 1 (1) Assam 2 (26) Bihar 1 (5) 07-2011 Total number confirmed measles outbreaks Total number of confirmed measles cases NA NA 7 MCUP activity completed by Post-MCUP Surveillance data from MCUP districts # MM-YYYY Total number of confirmed measles outbreaks Total number of confirmed measles cases 12-2010 12-2011 0 0 353 06-2012 08-2012 0 0 NA NA 01-2011 01-2012 0 0 MM-YYYY Reference period (until) 2 (15) 06-2011 2 82 02-2012 08-2012 0 0 1 (5) 07-2010 14 546 07-2011 07-2012 0 0 2 (5) 03-2011 1 15 03-2012 08-2012 0 0 NA NA 03-2011 03-2012 0 0 Gujarat Jharkhand Madhya Pradesh 1 (5) 2 (19) 07-2011 7 238 03-2012 08-2012 0 0 1 (5) 07-2010 5 354 01-2011 01-2012 0 0 2 (13) 01-2011 8 492 01-2012 08-2012 0 0 1 (5) 12-2009 4 211 12-2010 12-2011 2 54 2 (5) 03-2011 3 60 03-2012 08-2012 0 0 1 ( 26) 23 1111 2 54 2 (83) 28 1240 0 0 Rajasthan Grand Total Measles second opportunity – India 21 Data as on 13/08/2012 Summary Of 14 states implementing measles SIA, 6 states (Assam, Bihar, Gujarat, Jharkhand, MP & Rajasthan) have lab supported measles surveillance data to make before-after comparisons – The ‘post-’ window for phase-2 activity is <1 year (Range: 1-7 months) for all states – Surveillance sensitivity is variable across states and should be taken into account while interpreting results – Quality of MCUP activities have also varied among states Overall, in phase 1 & 2 districts SIA Upto 1 yr before SIA Upto 1 yr after SIA Outbreaks Measles cases 51 2351 2 54 Overall the MCUP strategy has been effective in reducing measles transmission In measles 2nd dose states the size and frequency of measles outbreak reduced Measles second opportunity – India 22 Thank-You Measles second opportunity – India 23