Enzymes for CIP
I & I Applications
4/13/2015
2009-08012-01
2
4/13/2015
NOVOZYMES PRESENTATION
CIP/Membrane cleaning
 Process industry Cleaning in Place = CIP
 Organic deposit found in pipes, tanks and industrial equipment
are efficiently removed by enzymes
 CIPzyme for dairy membrane cleaning
 Celluclean for Brewing membrane cleaning
 Lipex, Flavourzyme, Pectinex Ultra SP-L for Food processing lines
3
4/13/2015
NOVOZYMES PRESENTATION
Benefits of enzymes in Food & Beverage CIP
 Improved cleaning targeting specific organic problem soils with
the right enzyme
 Extended lifetime of equipment (e.g. membranes, pipes, tanks)
by cleaning under mild conditions
 Higher productivity
 Reduced downtime
 Increased filtration flowrates





Less chemicals and process aids (e.g. kieselgühr)
Lower temperatures and energy consumption
Reduction of water consumption
More environmental friendly cleaning procedure
Less risk of accidents to people
4
4/13/2015
NOVOZYMES PRESENTATION
CIP/Membrane cleaning
 Removal of washing solution and residual enzymes is
critical
 Novozymes offer a rapid test kit for lipase detection
 Inactivation and validation procedure to be developed
by Detergent formulator or end-user
 Novozymes assume no liability for problems with
residual enzyme activity in process equipment
 No use of enzymes on open hard surfaces without
case by case safety approval
5
4/13/2015
NOVOZYMES PRESENTATION
NZ positioning in I&I
– Dairy membrane cleaning and CIP
Novozymes
preferred
products
CIPzyme
Selling points
Synergistic effect of
Lipase and Protease
for Dairy membrane
cleaning
Competitor
product
Caustic and acid
NZ product
discriminator
Superior removal of
problematic lipidprotein fouling and
residues in a.o.
heatexchangers
6
4/13/2015
NOVOZYMES PRESENTATION
NZ positioning in I&I
– Brewing membrane filtration, Food processing cleaning
Novozymes
preferred
products
Celluclean
Flavourzyme
Pectinex Ultra SP-L
Lipex
Selling points
Competitor
product
NZ product
discriminator
Betaglucan removal
Eliminates health risk
under mild conditions Traditional filtration
of kieselgühr
gives superior
with Kieselgühr?
Targeted cleaning
Brewing membrane
Equipment lifetime
filtration
Higher degree of
protein hydrolysis
under mildly acidic
conditions
CIP food industry
(marmelade, juice
production, cider)
Fat degradation and
in-depth removal
Acid wash
Unique solution in
selected case
Detergents
Lifetime of expensive
equipment
7
4/13/2015
NOVOZYMES PRESENTATION
Hydrolytic activity
CIPzyme offers far superior cleaning than
single enzymes
Minutes
HYDROLYSES ON HOMOGENIZED MILK (S=0.4% DRY MATTER)
ENZYMES USED ARE PROTEASES, LIPASES AND CIPZYME
TEST METHOD: PH-STAT AT 50ºC, PH=8
CIPZYME IS A
COMBINED
PRODUCT,
CONTAINING
PROTEASE
AND LIPASE,
WHICH
CREATE A
SYNERGISTIC
EFFECT ON
THE
HYDROLYTIC
EFFECTS
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4/13/2015
NOVOZYMES PRESENTATION
Benefits of CIPzyme
CIPzyme is a product optimized for the use
in dairies and an enzyme preparation with
proteolytic and lipolytic activities
Benefits of CIPzyme:
 Maximizing equipment utilization
 Improved and targeted cleaning
 Extended equipment lifetime
 Lower consumption of chemicals
 Lower temperatures and lower energy
consumption
 Reduction of the water consumption
 More environmental friendly cleaning
procedure
 Less risk of people related accidents