Mountain West Research Consortium Clinical Translational - CTR-IN

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Mountain West Research Consortium

Clinical Translational Research –

Infrastructure Network

The Mountain West CTR-IN

Robert D. Langer, MD, MPH

Principal Investigator

Research Professor of Allied Health Sciences, UNLV

Associate Dean for Clinical and Translational Research and Professor of Family Medicine-Las Vegas, UNSOM

NIGMS Award: 1U54GM104944-01A1

What is it?

 $20 million 5 year NIH Grant under the IDeA Program

 Involving 13 universities across the 7 IDeA states in the Mountain

West Research Consortium

What are the 7 Mountain West states?

Alaska

Hawaii

Idaho

Montana

Nevada

New Mexico

Wyoming

Support: to foster Clinical and Translational Research

(CTR) according to NIH Definitions for Core Resources to facilitate the development of researchers moving into CTR

BOOTSTRAP CTR ACROSS THE

MOUNTAIN WEST

We will sink or swim based on the increase in “R-level” translational and clinical research that we achieve across the region over the next 4 years

“a rising tide that …

… lifts all ships.”

Who is in it?

 UNLV [host]

 UNR/UNSOM

 U. Alaska – Anchorage

 U. Alaska – Fairbanks

 U. Hawaii – Manoa

 Boise State U.

 Idaho State U.

 U. Idaho

 Montana State U.

 U. Montana

 New Mexico State U.

 U. New Mexico

 U. Wyoming

What will it do?

 Provide pilot grants of $40,000-$75,000/yr

 Support Mini-Sabbatical and Visiting

Scholar awards to build collaborations

 Provide infrastructure and services through Key Component Activities

Funding preference

 Promising Early Career or New

Investigators developing clinical or translational research programs

 Established Investigators moving from bench to translational or clinical

 Projects focused on health issues relevant to the region, including those in rural and vulnerable populations

What will it do?

 Use an NIH-style approach to applications and funding

 Model the processes that clinical and translational investigators need to master to compete successfully for

NIH support

Key Component Activities (KCAs)

 Education, Mentoring & Career

Development KCA

 Study Design & Biostatistics KCA

 Pilot Grant KCA

 Administrative KCA, including editorial support, award management, Annual

Meeting

 Education

 Mentoring

 Study Design

 Biostat

 Annual Meeting

ALL AVAILABLE regardless of whether you’ve received a competitive award from the CTR-IN

What will it do?

Hold an Annual Meeting to share science, motivate, build collaborations, & conduct study business that will:

 rotate across the 13 partner institutions

 feature an annual research theme relevant to health in the region

 bring together supported investigators, interested researchers from the region, key administrators from partners, external scientists, the regional biostat team, and senior project staff

First Annual Meeting at UNLV June 23 – 25, 2014 free registration, hotel rate ~ $100/night

What’s the current status?

 Round 1 Pilot Grants:

 24 applications, 6 awarded

 Round 1A Pilot Grants:

 63 applications, 14 awarded

Year 1 Pilot Grants

Boise State

Idaho State

Montana State

New Mexico State

U Alaska - Anchorage

U Alaska - Fairbanks

U Idaho

U Montana

U Nevada Las Vegas

U Nevada Reno

U Wyoming

Round 1 Round 1A Total

0 3 3

0

2

1

1

1

3

0

0

0

0

1

1

1

1

1

1

1

1

2

1

1

0

6

1

14

0

3

1

1

20

2

4

2

What’s the current status?

 Round 2 Pilot Grant RFA for 7/1/14 – 6/30/15:

 Letters of Intent with Abstacts were due 3/7/14

 122 LOIs with Abstracts received

 Invitations to submit 3/14/14

 Applications due 4/25/14

 Awards announced at Annual Meeting 6/25/14

 Earliest start date 7/1/14

 All information at: ctrin.unlv.edu

Letters of Intent for Year 2 Pilot Grants

U. Alaska Anchorage

U. Alaska Fairbanks

Boise State U.

Idaho State U.

U. Idaho

Montana State U.

U. Montana

New Mexico State U.

UNR

UNLV

U. Wyoming

5

9

8

7

3

14

8

5

23

30

10

Total 122

Visiting Scholars

 Call still open

 Funds must be expended by 06/30/14

 4 applications to-date, all awarded

 U Montana – to PG Awardee

 UNLV – to PG Awardee

 U Hawaii

 UNLV

PEOPLE!

Your First Call …

Your Local Concierge

http://ctrin.unlv.edu/?page_id=447

Senior Leadership

Administrative Core

Bob Langer, UNLV, PI

Jim Kenyon, UNR, Proj Coord.

Carl Reiber, UNLV, Assoc. Dir.

John Foreyt, UNSOM, Eval. Dir.

Education & Mentoring

Jillian Inouye, UNLV, Directorer

Bruce Shiramizu, UH, Mentoring

Pope Moseley, UNM, Mentoring

Merle Kataoki-Yahiro, UH, Educ

Craig Molgaard, UMT, Educ

Pilot Grants

Curtis Noonan, UMT, Director

Bill Shuttleworth, UNM, Assoc. Dir.

Design, Epidemiology, Biostat

Pope Moseley, Director

UNM CTSA: Richard Larson

website

ctrin.unlv.edu

NIGMS Award: 1U54GM104944-01A1

Mountain West CTR-IN Organizational Structure

Governance and Membership

Steering Committee

Robert Langer, MD, MPH, Principal Investigator

Jim Kenyon, PhD, Project Coordinator, Partners

John Foreyt, PhD, Project Coordinator, T&E

Rafael Gorospe, MD, PhD, Project Officer

Maria Canto, DDS, MS, MPH, Project Scientist

AFFILIATION COLOR

CODE

UNLV

UNSOM

U. New Mexico

U. Montana

NIH

Other Institutions

Internal Advisory Committee

Carolyn Yucha, PhD, Co-Chair

Thomas Schwenk, MD, Co-Chair

VPRs of all 13 Partner Universities

Robert Langer, MD, MPH, PI, ex oficio

Jim Kenyon, PhD, Project Coordinator, ex oficio

Principal Investigator

Robert Langer, MD, MPH

External Advisory Committee

6 to 10 External Scientists from outside the 7 state region

Admin KCA

Robert Langer, MD, MPH, KCA Director

Carl Reiber, PhD, Assoc. Director

Jim Kenyon, PhD, Project Coordinator

Track & Eval Unit

John Foreyt, PhD,

Project Coordinator

Concierges

Jill Zimbelman,

Lead Concierge

Regional Network

Pilot Grant KCA

Curtis Noonan, PhD, KCA Director

Executive Committee

PI

2 Project Coordinators

3 [4 with PI] KCA Directors

Assoc. Director, Admin KCA

Lead Liaison

CTSC Coordinator

Educ & Mentoring KCA

Jillian Inouye, PhD, KCA Director

Mentoring Unit Education Unit

UNM CTSC

Richard Larson, MD, Coord.

CRDEB KCA

Pope Moseley, MD, KCA Director

Regional Biostatistician Network

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