HELEN KNAGGS, PH.D VICE PRESIDENT, GLOBAL RESEARCH AND DEVELOPMENT, NUSKIN DALE KERN SENIOR SCIENTIST, GLOBAL RESEARCH AND DEVELOPMENT, NUSKIN WORLD CLASS SCIENTISTS WITH AN ARRAY OF EXPERTISE WORLD CLASS SCIENTIFIC ADVISORY BOARD A. Kimball Harvard Dermatologist C. Djerassi Stanford Father of oral contraceptives L. Packer Father of antioxidants D. Bearrs Huntsman Cancer Center Pioneer in Cancer genetics M. Kuro-o Discoverer of Klotho aging gene G. Halperin Pioneer in Immunology M. Wanner Harvard Dermatologist H. Wagner Pioneer in Phytomedicine P. Cox Pioneer in Ethnobotany K. Nakanishi Father of Ginko R. Weindruch Pioneer in Aging Research L. Bohlin Pioneer in Natural Products T. Prolla Pioneer in Aging Research L. Mitscher Pioneer in Green Tea Z. Draelos Duke Dermatologist COMPETITIVE ADVANTAGE TARGETING THE SOURCES OF AGING GENE CHIP TECHNOLOGY DNA Microarray Gene Map Over 20000 Genes Small set of robust biomarkers for rapid screening of nutrients and phytochemicals GENE CHIP TECHNOLOGY ITS ALL ABOUT BALANCE Factors influencing signs of aging Anti-Aging Science Factors influencing signs of youth Antiaging science IDENTICAL TWINS AGE AT DIFFERENT RATES Add Reference Guyuron B, Rowe DJ, Weinfeld AB, Eshraghi Y, Fathi A, Iamphongsai S. Factors contributing to the facial aging of identical twins. Plast Reconstr Surg. 2009 Apr;123(4):1321-31. CHARACTERISTIC FEATURES OF SKIN AGING BREAKDOWN OF PROTEINS Skin Proteins FIRMING FOCUSED YGC* ANTI-AGING SCIENCE Skin Structure Improves Sagging Firming Contours Defines *A subset of the Skin Structure YGC NU SKIN EXCLUSIVE ACQUISITION NOX TECHNOLOGIES ACQUISITION • Patented anti-aging technology • Incorporated in ageLOC Transformation and Spa Gels • Anticipated acquisition Q4 2012 PATENTS PROTECT OUR INNOVATIONS Anti-Aging Science Antiaging science PUBLICATIONS Anti-Aging Science Antiaging science EXCLUSIVE & PROTECTED • • • • • 18 8 14 26 3 Patents filed or pending Articles published Oral presentations Scientific posters Prestigious awards AGELOC IS A PROVEN BRAND OVER $1 BILLION IN AGELOC SALES SINCE Q4 2009 YOUTHFUL SKIN “SNAP BACK” QUALITY • • •• • •• • •• • ALL THE SAME GREAT BENEFITS PLUS… Contains Ethocyn®, clinically proven to improve the key component of firmofskin Targets the sources aging Study participants 166% increase in elastin Contains ageLOCaveraged Proprietary Blend with a twice-daily application of Ethocyn* More firming ingredients Helps contourimprovement and firm the in skin for askin morefirmness youthful Continuous overall appearance Consumer feedback: it feels better on the skin Defines skin neck, and jawline Majority of around people the saweyes, results in chin, one week** Helps protect the skin from oxidizing free radicals CLINICAL STUDY improvement over baseline 70% 66% 60% 55% 53% 50% 44% 41% 40% 30% 30% 20% 18% 21% 10% 0% Overall Skin Firmness Firmness Around Eyes Week 1 Week 4 Week 8 Week 12 CLINICAL RESULTS Percent of Subjects 90% 80% 80% 80% These results represent the highest response to a Tru Face Essence product that Nu Skin has ever seen in these time frames! 70% 60% 55% 55% 50% 40% 30% 20% 10% Week 1 0% Overall Skin Firmness Firmness Around Eyes Week 12 CLINICAL RESULTS 6 years 0% 7 years 3% 5 Years 12% 4 Years 9% 1 Year 53% 3 Years 9% 2 Years 14% Number of years younger subjects reported for skin appearance at week one Leave undefined skin in the past and enjoy firmer, younger looking skin today and in the future, with ageLOC Tru Face Essence Ultra.