Getting Started in Research Kathryn Adcock Wellcome Trust University of Birmingham 27 September 2011 Outline • Wellcome Trust • who we are • what we fund • Applying for funding • the written application • the interview Wellcome Trust •We were established in 1936 •We are funded from a private endowment •We spend approximately £600 million on grants per year •Our interests range from science to the history of medicine to public engagement Our vision and mission Our vision is to achieve extraordinary improvements in human and animal health Our mission is to support the brightest minds in biomedical research and the medical humanities Five major challenges 1) Maximising the health benefits of genetics and genomics 2) Understanding the brain 3) Combating infectious diseases 4) Investigating development, ageing and chronic disease 5) Connecting environment, nutrition and health Medical research: Extraordinary opportunities • Phenotyping people • Physiology • Pathology • Medical imaging • Informatics • Genetics • Measuring the environment • unpicking complex disease • understanding complex processes • new diagnostics, therapeutics and vaccines Wellcome Trust funding schemes Support for individual researchers Principal Research Fellowships BASIC Senior Research Fellowships Sir Henry Dale Fellowships NIH-WT PhD Programmes WT-MIT Postdoctoral Fellowships Four-year PhD Studentship Programmes Sir Henry Wellcome Postdoctoral Fellowships CLINICAL Senior Investigator Awards Clinical PhD Programmes New Investigator Awards Research Training Fellowships Early Postdoctoral Training Fellowships PhD PUBLIC HEALTH & TROPICAL MEDICINE Postdoctoral Training MB/PHD Fellowships Intermediate Clinical Fellowships Senior Research Fellowships Training Fellowships in Public Health & Tropical Medicine Masters Fellowships Principal Research Fellowships Intermediate Fellowships in Public Health & Tropical Medicine Senior Fellowships in Public Health & Tropical Medicine EARLY INTERMEDIATE SENIOR Wellcome Trust Clinical Fellowships Research Training Fellowship Intermediate Clinical Fellowship Postdoc Training Fellowship for MB/PhD graduates Schemes administered by the Trust Early Postdoctoral Training Fellowship for Clinician Scientists Trust schemes administered by host institutions Clinical PhD Programmes Training Programmes for Clinicians in Translational Medicine & Therapeutics Senior Research Fellowship in Clinical Science Principal Research Fellowship New Investigator Award Senior Investigator Award Trust-administered schemes Research Training Fellowships • Who? • for medical, dental, veterinary and clinical psychology graduates • little or no research training to date • Why? • to develop a career in academic medicine • MD or PhD Research Training Fellowships • What? • high-quality, hypothesisdriven research project • up to 3-years • clinical salary • research expenses Research Training Fellowships • Considered three times a year • Interviews in: • November/December • April • June/July • No preliminary application required • Trust staff happy to discuss plans Next deadline for full applications: 17 September & 8 February 2013 Imperial-administered schemes PhD Programmes for Clinicians • Programme is tailored to the unique needs of clinicianscientists • Programmes provide: • a structured, well-mentored environments • access to high-quality research environments Apply to institution directly. Look out for adverts in BMJ, Imperial & Trust websites – coming soon! Interdisciplinary Training Programmes for Clinicians in Translational Medicine and Therapeutics • to provide clinicians with the expertise to design and conduct studies that aim to develop and evaluate novel therapies in humans • Partnerships • academic institution (Imperial) • industrial partner (GSK) Interdisciplinary Training Programmes for Clinicians in Translational Medicine and Therapeutics • Programmes at: • Imperial College London • University of Edinburgh/Scotland • University of Cambridge • Newcastle University Trust-administered schemes Postdoctoral opportunities and beyond… • Postdoctoral Training Fellowship for MB/PhD Graduates •Early Postdoctoral Training Fellowship for Clinician Scientists • Starter Grants for Clinical Lecturers (run by AMS) • Intermediate Clinical Fellowship • Senior Clinical Fellowship Applying for funding The Process Good idea Choose a funding agency & scheme Preliminary application stage? Write application University admin office Submit application External review Short-listing Committee Interview Committee Reject Fund Fellowships • How do we assess applications? • Person • Project • Place Tips on writing a good application Before starting your application…. • Read the application form and guidance notes carefully • Check deadlines to avoid rushed applications • Think about who you may need to contact for information/signatures • Is your boss going on holiday, to a conference etc? • Allow time for the application to be processed by the admin office • Warn people that your application is coming • Queries? Contact the funder’s office staff A ‘good’ application • A strong and original central hypothesis/research vision • Easy to understand and read • Consider all readers • avoid jargon • avoid abbreviations • check grammar and spelling • Requests for resources should be justified • Animal use and studies using human subjects should be carefully justified and power calculations provided, where appropriate A ‘good’ application • Not over- or under-ambitious • Takes into account the current literature (including conflicting opinions) • Clear research plan. • approach is feasible • realistic timescale • potential pitfalls and fall-back plans • Appropriate expertise • sponsors, collaborators and research team A ‘good’ application • Get someone with a critical eye to read your application before you submit it • Very senior people may not have the time • Try someone outside your area The Interview Beforehand Practice, practice, practice!!! There is no substitute for mock interviews Own the project Be familiar with recent advances in the field Find out who is on the panel & know what they do Afterwards • Don’t call us, we’ll call you • Yes – celebrate and get to work! • No – ask for feedback, many funders will give detailed advice • Will a re-submission be considered if so what must change? Questions? www.wellcome.ac.uk