Methods for costing NCD prevention and control Workshop on Country Perspectives on Decision Making for control of chronic diseases Institute of Medicine of the National Academies July 19-21, 2011 Karin Stenberg, Department of Health Systems Financing 1| Acknowledgements The analysis was led by Dr Dan Chisholm, Dr Dele Abegunde and Dr Shanthi Mendis of World Health Organization, with contributions from many WHO experts. The support and contribution of the American Cancer Society to this work is gratefully acknowledged. For tobacco costing, the contributions of Dr Ioana Popovici of Nova Southeastern University and Professor Michael French of the University of Miami were funded by Bloomberg Philanthropies and the World Lung Foundation, while the time and contributions of Judith Watt was funded by the Framework Convention Alliance. 2| Economic evidence for NCD prevention & control – a story with 3 parts – 1. Economic burden (the size of the problem): Micro-economic impact (at level of households and firms) Macro-economic impact (at aggregate level of society) 2. Priorities for investment (potential solutions): Synthesis of available cost-effectiveness evidence Identification of 'best buys' for low- and middle-income countries 3. Costs of scaled up action (financial 'price tag'): Resource needs associated with enhanced coverage / implementation Budgetary gaps and implications 3| Cost of scaling-up for NCDs: immediate and future steps 1. Global 'price tag' for all Low and Middle Income Countries (LAMIC) (for input into NCD summit; Sept 2011) – a financial planning tool for scaled-up delivery of a defined set of population-wide and individual health care interventions. 2. Country-level use / contextualization (for national planning; 2011-2012) 3. Incorporation into OneHealth (for integrated health system planning; 2012) 4. Modelling of health gains / return on investment (impact analysis; 2012 ?) 4| What to scale up? 1. Scope (WHO NCD action plan): Risk factors: tobacco & (harmful) alcohol use; unhealthy diet & physical inactivity Diseases: CVD and diabetes; cancers; respiratory disorders (asthma, COPD) 2. 'Best buys': Interventions that are very cost-effective but also feasible, low-cost and appropriate to implement within the constraints of the local health system 'Very cost-effective' = one year of healthy life is obtained for less than average annual income per person [GDP per capita] Interventions that do not meet all of these criteria - but which still offer good value for money and have other attributes that recommend their use – can be considered as 'good buys' (we also cost this expanded intervention set) 5| Summary of 'best buys' Condition Interventions Tobacco use (4) Tax increases; smoke-free indoor workplaces & public places; health information / warnings; advertising/promotion bans Alcohol use (3) Tax increases; restrict retail access; advertising bans Unhealthy diet & Reduced salt intake; replacement of trans fat with polyunsaturated physical inactivity fat; public awareness about diet & physical activity (3) CVD & diabetes (2) Cancer (2) 6| Counselling & multi-drug therapy (including glycaemic control for diabetes) for people with >30% CVD risk (including those with CVD); treatment of heart attacks with aspirin Hepatitis B immunization to prevent liver cancer; screening & treatment of pre-cancerous lesions to prevent cervical cancer 2008-2013 Action Plan for the WHO Global Strategy for the Prevention and Control of Noncommunicable Diseases Addressing population risk factors Primary care Estimating the cost of scale up: information needed Parameter Definition Data source(s) Population Total population of country UN population division statistics Prevalence % of population with disease / risk factor exposure (by age & sex) Global burden of disease estimates: Comparative Risk Assessment study NCD surveillance (e.g. Infobase) Coverage % of population in need in receipt of intervention Current coverage: Survey data Target coverage: expert consensus Resource use Resources needed to implement intervention Treatment protocols, costing studies Unit cost / price Cost per unit/item of resource use Drug prices from MSH; WHO costing data base (CHOICE) – e.g., salaries, media costs, per diems, etc. 7| Estimating the global cost of scale up: 2011 study produces a more extensive estimate Parameter 2007 2011 (Lancet chronic disease series) (forthcoming WHO report) Countries 23 (80% of LAMIC burden) 42 (90% of LAMIC burden) Scale-up period (price year) 2006-2015 (in 2005 prices) 2011-2025 (in 2008 prices) NCDs / risk factors Tobacco use; high BP; CVD All elements of NCD action plan (4 risk factors, 4 diseases) Tobacco control measures (4); salt reduction (1); multi-drug therapy for those at high risk (1) Core set: all 'best buys' (14) Expanded set: range of 'good buys' Interventions 8| Different implementation time in different contexts, depending on existing health system and policy environment Scale up of patient interventions Scale up of activities for population interventions (policy implementation): Based on available assessment of current enforcement or 'performance' of countries with respect to e.g., tobacco control policy, alcohol control policy. 4 stages of policy implementation: • Planning stage (year 1) • Policy development (year 2) • Partial implementation (year 3-5) • Full implementation (year 6 onwards) 9| Resource needs matrix for NCD policy instruments Stage of policy development Human resources Training Meetings Planning (year 1) Program management; administration Strategy / policy analysis Stakeholders Development (year 2) Advocacy; law Legislation Intersectoral collaboration Awareness campaigns Partial implementation (years 3-5) Inspection Regulation Monitoring Counteradvertising Full implementation (year 6 onwards) Enforcement 10 | Evaluation Mass media Supplies & equipment Other Office equipment Baseline survey Opinion poll Vehicles, fuel Follow-up survey Cost of scaling up : Illustrative example A 20% rate of prevalence of smoking in a total population of 1 million persons would give a population in need of 200,000 individuals. All these individuals could benefit each year from a brief intervention in primary care that, say, costs $1 per case to deliver. • Cost of current coverage: If coverage of the brief intervention was currently only 10%, the total annual cost would be $20,000 (200,000 * 10% * $1). • Cost of target coverage: If scaled up to a higher desired level of coverage (such as 50%), the total cost in that future year will jump five-fold to $100,000. • Incremental cost: Difference between the current and target level of coverage ($80,000). • Cost per capita: Division of total or incremental costs by total number of people in the population (annual cost per person would rise from $0.02 to $0.10, an increment of $0.08). 11 | Costing population interventions (example) 12 | Costing primary care services Ingredient-based costing, specific by level 13 | Costing primary care services (contd.) 14 | Modeled costs indicate variability of resource needs for scaling up NCD interventions Median annual cost per capita of tobacco control, 2011-2025 $0.50 $0.45 Cost per capita (I$) $0.40 $0.35 Lower IQR Min Median Max Upper IQR $0.30 $0.25 $0.20 $0.15 $0.10 $0.05 $- 15 | Low-income countries (N=14) Lower middle-income countries (N=13) Upper middle-income countries (N=15) Cost of scaling up NCD prevention: population-based tobacco and salt reduction strategies (Source: Asaria et al, Lancet 2007) Over 10 years (2006–2015), 13·8 million deaths could be averted 16 | Strengths and limitations STRENGTHS Comprehensive assessment of 'best buys' and 'good buys' Standard methodology used by WHO to derive global 'price tags' and country costing spreadsheets (similar to TB, malaria, child health, etc). Ingredients based (Quantity x Price ) – easy for countries to review and validate Assessment of current policies and health system as starting point LIMITATIONS Lacks assessment of health gains; does not model changes in epidemiology over time as preventive interventions are scaled up. May need to be expanded to cover a broader intervention set for country planning. Does not model health system investment needs. Financial sustainability assessment needs to be done separately. 17 | Next steps Report on global price tag launched before UNGASS Sept summit NCD cost templates available for countries to validate and use Integration of NCD module into OneHealth tool will need to consider broader package, including other renal and liver diseases, gastrointestinal diseases, and mental disorders Develop model for analysis of health impact 18 | Additional slides 19 | 20 | Estimating the cost of NCD scale up (2011) - 42 countries (each > 20m popn; together, account for 90% NCD LAMIC burden) Low-income countries (14) Afghanistan; Bangladesh; Côte d'Ivoire; DPR Korea; DR Congo; Ethiopia; Ghana; Kenya; Myanmar; Nepal; Nigeria; Sudan; Uganda; Tanzania Lower-middle China; Egypt; India; Indonesia; Iraq; Morocco; Pakistan; income countries Philippines; Sri Lanka; Ukraine; Uzbekistan; Viet Nam; (13) Yemen Upper-middle Algeria; Argentina; Brazil; Colombia; Iran; Kazakhstan; income countries Malaysia; Mexico; Peru; Romania; Russian Federation; (15) South Africa; Thailand; Turkey; Venezuela 21 |