Epidemiology in the Hospital Setting Benjamin A. Rybicki, PhD Senior Scientist, Henry Ford Hospital Henry Ford Health System Females Age # Males % of pop # Total % of pop # % of pop 0-17 10529 7.6% 10814 7.8% 21343 15.4% 18-29 8887 6.4% 7667 5.5% 16554 11.9% 30-39 6543 4.7% 4775 3.4% 11318 8.1% 40-49 10761 7.7% 8362 Age 6.0% Females 19123 Males 13.8% 50-59 14400 10.4% 11498 0 - 178.3% 63458 25898 66583 18.6% 130041 60-69 11186 8.0% 7846 5.6% 42306 21002 38462 13899 39189 15.1% 32150 10.0% 81495 70-79 9816 18 - 29 7.1% 6053 30 - 39 4.4% 80+ 5855 4.2% 3976 40 - 49 2.9% 50-59 62961 45.3% 60-69 51924 9831 52733 138968 31578 46138 7.1% 47000 100.0% 29638 98062 13773 11710 25483 9943 6764 16707 304177 279172 583349 Total 76007 54.7% 70-79 80+ Total Total 70612 99733 61216 Respiratory Research Cardiovascular Epidemiology Epidemiology Epidemiologists Population Database Interviewers Molecular Biology Human PopulationsAbstractors Molecular Bio Laboratory Laboratory Prog/Data Mgrs. Data Entry Cancer Mol Biologists Statistics Statistics Biostatisticians Neuro Biostatistics & Research Epidemiology www.henryford.com/body.cfm?id=39207 BRE Organizational Structure Biostatisticians 13 Epidemiologists 16 Data Management & Programming 10 Data Entry 2 Project Support 10 Molecular Epid Research Lab 6 Abstracting, Interviewing, RN/LPNs, MAs 36 Computer Facility 4 Grants Managers 2 Total Staff 103 Secretarial 3 Administrative Manager 1 A Nested Case-Control Study using a Pathology-based Cohort Benign Cohort 1990 – 2006 N=8,117* PSA test +/- 1 year of benign specimen (N=7,122) Yes Prostate cancer diagnosis on or before 12/31/2010 Cases N=1,441 Controls N=5,681 ≥ 1 year between benign specimen and cancer diagnosis N=1,136 Aim 1 & Aim 2 Aim 3 Benign tissue available for study N=931 Tumor tissue available for study N=698 No ≥ 1 year of follow-up after benign biopsy N=4,431 Case-Control Matching: Age, race, and follow-up duration 800 case-control pairs 650 case-control pairs Benign tissue available for study N=3,633 Summary •At Henry Ford, epidemiologists lead and co-lead research in step with the mission of the health system. Biostatisticians are often co-investigators on epidemiologist-lead research, but focus most on statistical issues across multiple projects. • Epidemiologists tend to favor observational studies, but often employ methodologies developed by basic science researchers and team with clinical researchers doing intervention studies. • Investigators who want to use population data to address a research question can benefit from interactions with an epidemiologist.