MSTP Fellowship and Career Development Support Alison Hall, Ph.D. Office of Graduate Education Career Development Why a fellowship Mentor’s advice Letters of recommendation Pilot data Goal setting What budget can be used for Write a Compelling story Peer advice De-Mystifying the Process 1.Support as an MSTP student 1. Fellowship—NIH F30/31 2. Non-federal funding 2. Next funding steps after graduation 1. Career Development—NIH K08 2. Independence—NIH K02/R01 3. Components of an effective proposal • National Research Service Awards (NRSA) – F30, 31 Predoctoral Fellowships – F32 Postdoctoral Fellowships • Career Development Awards – K01 Mentored Research Scientist Development Awd – K08 Mentored Clinical Scientist Development Awd – K23 Mentored Patient-Oriented Research – K99/00Pathway to Independence Award Who has NIH support? NIH Reporter http://projectreporter.nih.gov/reporter.cfm Examples… Graduate Education Office.. The NIH NRSA Ruth L Kirschstein Stipend FY 2011 Predoctoral Postdoctoral $21,600 Years of Experience: 0 $38,496 1 $40,548 Tuition Training Related Expenses Predoctoral Trainees: $4,200 Postdoctoral Trainees: $7,850 F award http://grants.nih.gov/training/f_files_nrsa.htm F KIOSK Up to 3 years funding Tips and samples http://grants.nih.gov/grants/grant_tips.htm_process.htm Deadlines 3 times per year usu Apr 8, Aug 8, Dec 8 electronic submissions! F30 / 31 funding for MSTP students F31 Diversity PA-11-112 for URM students supports PhD phase, includes most institutes F31 NIH PA-11-111* supports PhD phase F30 Parent MD-PhD NIH PA-11-110* supports MD and PhD phases *NCI, NIA, NIAAA, NIDCD, NIDCR, NIDA, NIMH, NINDS, NCCAM NRSA predoctoral proposal components: Specific Aims (1 page) 3 aims Research Strategy (6 pages) Sponsor/co-sponsor info Respective Contribution (1 page) Responsible Conduct of Research (1 page) Goals for fellowship training and career (1 page) Activities planned under this award (1 page) Dissertation and other research experience (2 pages) Three letters of reference Biosketch including courses and grades More than research--incorporate training goals Reviewer Criterion Scores Applicant Sponsors, collaborators Research Training Plan Training Potential Institutional environment, commitment to training new techniques new collaborators present at meetings, go to courses timeline including publication plan advisory committee meet six mos for feedback Non-Federal (Foundations, Corporations, etc) Grantsnet Advanced search “Research Funding” , Individual “early doctoral student” “PhD dissertation student” Research area (optional, choose many) Often single deadline per year …Plan to apply to Feds and Foundations Example American Society Of Microbiology Robert D. Watkins Minority Graduate Fellowshiphttp://www.asm.org/Education/index.asp? bid=6278 3 years graduate coursework completed by activation date mentored by an ASM member May 1 deadline annually Example American Heart Association (Great Rivers affiliate) Cardiovascular and stroke research $22,000 plus $1K fringe 1-2 years, option 3 Jan deadline, starts July Inform Cliff before preparing the application MSTP specific instructions maximum allowable period, 6 yr max on an NIH training mechanism Choose best funding for MD-PhD training incl covering the MD phase if possible Project max. training period, max. tuition— anything left over will revert back to the NIH 2. Next funding steps after graduation Career Development Awards K01 Mentored Research Scientist Development Awd K08 Mentored Clinical Scientist Development Awd K23 Mentored Patient-Oriented Research K99/00 Pathway to Independence Award Provides protected time for mentored research Get pilot data during residency/fellowship K08 Mentored Clinical Scientist Development Award K Kiosk http://grants.nih.gov/training/careerdevelopmentawards.htm For clinically trained persons to pursue research careers in basic or clinical sciences Must apply within 3 years of clinical training partial salary (up to $100K) some research costs (30-50K) up to five years Not uniform salary—see Institute!! (this is NCI) 75% effort (50% surgery) The K08 Three letters of reference Specific aims 1 page All in 12 pages: Candidates background Career goals and objectives Career development plan/ training activities Training in RCR Research Strategy The K08 AGAIN Career Development Plan (very important) • learn new techniques, new area, fundable • present at meetings, review grants, courses • Update didactics • Timeline including publication plan • advisory committee familiar with research, career goals, meet six mos for feedback MD-PhDs are few, but successful! First-Time Applicants for R01 Grants by Degree (1964-2004) and Percentage Awarded (1964-2003) # physician investigators applying for first R01s little change for 3 decades Those proposing clinical work less successful Dickler, H. B. et al. JAMA 2007;297:2496-2501. Copyright restrictions may apply. 3. Components of an effective proposal Most applications electronic Assigned to Scientific Review Group Study section review NIH Scores 1 (great)- 9 (poor) Summary sheet http://grants.nih.gov/grants/partners/NexusImages/September06/submit.jpg Write for the Reviewers • Reviewers are: – – – – Smart Accomplished Dedicated Fair Phyllis McBride, Ph.D. p-mcbride@tamu.edu Write for the Reviewers • Reviewers are also: – Busy – Overworked – Skeptical – May not be as knowledgeable about the details Phyllis McBride, Ph.D. p-mcbride@tamu.edu A strong research idea passes the “so what” test What is the benefit of answering your question? Who will it help and how? Make a definitive statement on purpose of your research why it should be funded Specific Aims (1 p max) Propose 2 or 3 aims Provide a rationale—where did hypothesis come from? why is this a strong idea? Provide a hypothesis to be tested with a specific aim Have objectives that are measurable and focused Research Strategy (6 p max) background and significance no more than a page not a wikipedia on the subject!! lead to remaining question each paragraph Pilot data--perhaps a year of work? Plan to submit right after qualifier Research Strategy, continued How test hypothesis, what approach? Propose to learn two techniques within plan Describe who will teach you and how Include collaborators, letters as needed Cite, but do not expect reviewer to read papers Provide general scope of experiment Include “Anticipated outcome and Alternative interpretations” for each aim Sponsor/co-sponsor info research expertise training experience and success may need to choose add’l senior person describe when meet Responsible Conduct of Research IBMS 500 + advanced ethics Goals for fellowship training and career thesis committee composition, mtgs coursework CSH, other instns publications, national meetings Professional skills Plan to submit the research training proposal to several agencies; you can submit to many, but accept only one You will get a summary statement, and may have to resubmit—address questions in Introduction Every MSTP student is fundable—