Stereoisomers:
Optical Isomers
PART 2
CH21 Problem Solving Class
Sample Problem
Sample Problem
S
R
enantiomers
same
S
same
R
R
S
S
S
same
Review Problem
Review Problem
Diastereomers
Diastereomers
Sample Problem
Epimers: Special Diastereomers,
different with ONE chiral center
Sample Problem:
Meso Compounds
Meso Compounds
Meso Compounds
Meso Compounds
Sample Problem
Sample Problem
Racemic Mixtures & Resolving
Racemic Mixtures & Resolving
Review of Isomerism
Stereochem of Reactions
Stereochem of Reactions
Sample Problem
Sample Problem
Sample Problem
• Equal chance to attack both carbons from the top, vs. both
carbons from the bottom, which means you’ll have 2
racemic pairs (50:50)
• BUT THEN THESE RACEMIC MIXTURES aren’t 50:50 because
of the methyl group in the ‘up’ position… meaning it won’t
be a 25:25:25:25 mixture of all for, but a A:A:B:B ratio
Prochirality
Prochirality
• Using our RIGHT HAND RULE, try to see if you can get
a 1-2-3 with your right hand. The face where your
thumb points to is the Re face!
• Then with your left land, find 1-2-3, and you’ll
find the Si face.
Prochirality
• Using our RIGHT HAND RULE, try to see if you can get
a 1-2-3 with your right hand. The face where your
thumb points to is the Re face!
• Then with your left land, find 1-2-3, and you’ll
find the Si face.
Sample Problem
Sample Problem
Sample Problem
Sample Problem
Prochirality
Sample Problem
Sample Problem
Sample Problem
Sample Problem