Commas! English Commas Rule #1 Use a comma to set off a n oun of direct address (a person spoken to). Justin Bieber, come here, please! Have you gone, Michael? I want to go, Ronnie, with your peeps! Rule # 2 Use a comma to set off introductory words. No, I haven’t seen it. Well, I’ve changed my mind. Yes, the chimes are new. Rule #3 Use a comma to set off interrupters in a sentence. The answer, I think, is fifty-four. This calendar, in fact, is an old one. However, not all is lost. Rule # 4 Use a comma after the greeting of a friendly letter. Dear Brad Pitt, Yes…I will go out to dinner with you. Rule # 5 Use a comma after the closing of any letter. Sincerely yours, Maria Love, Brad Rule #6 Use a comma to set off words or phrases in a series. Furniture, linens, toys, and dishes were sold there. We ran a mile, swam a half mile, and biked a mile. Rule # 7 Use a comma to clarify a sentence. In the night time was extremely important. Compare to: In the night, time was extremely important. Rule #8 Use a comma between two or more descriptive adjectives. Bright, sparkling stars twinkled in the dark night. END