New Harvard Peristaltic Pumps R. Pelletier, September 2012 What is a Peristaltic Pump • Positive displacement pump • Fluid is contained within a flexible tube fitted inside a circular pump casing • A rotor with a number of "rollers", attached to the external circumference compresses the flexible tube. • As the rotor turns, the part of tube under compression is pinched closed forcing the fluid to be pumped to move through the tube. • Flow Rate depends on tubing I.D., length of tubing, and motor rpm. Peristaltic vs. Syringe Pumps Parameter Syringe Pump Peristaltic Pump Accuracy High (<0.25%) Low (>1%) Precision High Variable Reliability High High Needs Refill Yes (unless using valves) No Pressure High (>1,000 psi) Low (<50 psi) Flow Type Pulseless Pulsatile Multichannel Yes Yes Market Size <$50 M/year >$200 M/year Year Developed 1950's 1880's Peristaltic Markets Fluid Transfer & Volume/Time Dispensing in: • Academic Life Science • Pharmaceutical & Biotech • Food & Flavors • Chemical Industry • Semiconductor Near Term HA targets are Life Science and Pharmaceutical Sectors Application Areas • Large Volume Infusion • Sample Preparation • Recirculating Baths • Organ/Tissue Perfusion • Dosing/Filling • Dispensing Cell Culture Media • Large Volume Dispensing The Harvard Peristaltic Pump • Unique Architecture – Remote configuration • Interchangeable motor/heads – Versatility and wide range of flow rates • Digital Control - accuracy • Space Saving – use in incubators and hoods Flow Rate Ranges - 1 • P-70 Motor/Head – Low Flow perfusion and small volume dispensing • 5 Fluid Channels • 8 Rollers (smooth flow) • Flow from 0.001 to 70 mL/min per channel • Uses 3 collar tubing (0.13-2.79 mm ID) Flow Rate Ranges - 2 • P-230/Head – Organ/Tissue/Cellular Perfusion • 4 Fluid Channels • 8 Rollers (smooth flow) • Flow from 0.001 to 230 mL/min per channel • Uses 2 collar tubing (0.13-3.17 mm ID) Flow Rate Ranges - 3 • P-1500/Head – Bulk Fluid Transfer/Dispensing • 1 Fluid Channel • 4 Rollers • Flow from 0.01 to 1,500 mL/min • Uses straight tubing (0.8-8.0 mm ID) Controller Features • HA Touch Pad User Interface • Ease of Use • Tubing Library • Calibration • Timed or Volume Dispense/Delivery • Flow Ramps • Method Storage • Combine channels function for setting total flow • Constant Pressure Mode Quick Start Menu Pump Settings Settings allow for interchangeable drives/heads on one control unit Tubing Selection Icon indicates combined number of channels for flow rate. For example, P70 with 2 channels selected will have maximum flow of 140 mL/min Built in library allows for the selection of HA supplied tubing or tubing of the customer’s choice Timed or Volume Dispense Set Dispense by time or Volume Method Profiles Methods may be linked as well as stored Advanced Options allow for methods to be tied to I/O events and time delays Calibration Pump calibration may be for single channel, or combined flow from multiple channels Run Screen Method Preview Method when running showing status Advanced Options & I/O Capabilities Allow for timed start/stop Remote start Signal in or out at start/during/end of run I/O Ports – Back Panel Competition - 2 General Types of Peristaltic Pumps • Type 1 - Analog (similar to HA MP-II) • Sell for $500 - $1,200 • Older design electronics • Flow rates are approximate • No modern features • Difficult to calibrate • Limited I/O capability Competition • Type 2 • Digital – Sell for $1,500 to $4,000 • Advanced electronics • Allow for calibration and direct setting of flow Competition • Main Competitors – Digital • Cole Parmer • Ismatec/Reglo • Watson Marlow • Wheaton Scientific Competition • Cole Parmer mainly 1-2 channel systems • Ismatec/Reglo multichannel systems, but low level electronics. Sold through distributors. • Watson Marlow mainly OEM supplier of pump heads. Wheaton uses WM heads. Competition • Compete on capabilities and application – • Start with number of channels and flow rates • Digital capabilities • Product Configuration options Know the competitive product and be sure you are making a valid comparison. Competition • HA Pricing is competitive • For P-70, HA ILP=$2,990, Competitive range is $2,900- $3,200. • For P-230, HA ILP=$3,162, Competitive range is $3,000- $3,300 • For P-1500, HA ILP=$2,474, Competitive Range is $2,200-$2600 Not Direct Competition - low capability and low price HA MP-II Ismatec Ecoline Reglo Analog Masterflex CL Series Masterflex IP Series Competition - Direct Masterflex Digital Drive Ismatec Digital Drive Masterflex LS Series Ismatec Compact Digital Wheaton Omispense/Unispense Accessories • Optimized tubing sets available for all HA Models • Customers can use their own tubing • Tubing sales can be a repeat business opportunity HA Marketing Activities • Shipments to begin in November • Brochure and web site promotion/eBlast in October • New Pump Catalog with Peristaltics in October • Exhibit at Neuroscience meeting in October • Demo pricing of 50% from ILP for distributors Distributor Activities • Prepare web site content • Identify local beta users • Plan promotional activities New HA Peristaltics PN Description ILP 70-7000 Complete with P-70 Head $ 2,990 70-7001 Complete with P-230 Head $ 3,162 70-7002 Complete with P-1500 Head $ 2,472 70-7003 P-70 Head/Motor Only $ 2,070 70-7004 P-230 Head/Motor Only $ 2,185 70-7005 P-1500 Head/Motor Only $ 1,725 70-7006 Controller only $ 1,092