HPV and Cervical Cancer What is cervical cancer ? Cervical cancer occurs in the cervix (the entrance to the womb) In England, about 750 women die from cervical cancer every year Human papillomavirus (HPV) • HPV stands for human papillomavirus, which is a type of virus infection • these viruses are mainly spread by intimate skin-to-skin contact during sexual activity • they enter the surface of the genital skin, vagina and cervix through tiny areas of damage that cannot be seen • boys can also catch HPV and they are mainly responsible for transmitting it to girls How HPV causes cancer • most women will be infected with HPV at some point in their lives without even being aware of it • normally it goes away completely when the immune system clears the virus from the cervix • in some women the infection can stay in the cervix for many years, causing cell damage which if left untreated can develop into cancer 1. infectious virus particles enter the cervix through tiny abrasions 3. the cell damage can be seen by cervical screening 2. the virus mixes with the cells’ DNA and spreads by invading other cells Screening also prevents cancer HPV vaccination in Year 8 • HPV vaccine contains tiny particles that pretend to be like the HPV virus, which helps the body to protect itself by making antibodies • girls who are vaccinated at age 12 or 13 develop antibody levels that are much higher than those who are vaccinated at older ages • because of this, girls in Year 8 will develop protection that will last for at least twenty years without needing another injection What happens next ? • before getting the vaccine, you will get a leaflet and consent form to take home to read and discuss with your parent or carer • your parent is asked to sign the consent form • it is important that you return the consent form to school so that we can immunise you • you will need three injections in your upper arm over a period of six months • the injections are given at school by a nurse • you may feel stinging as the injection is given • other side effects (in about 1 in 10 girls) include headache or tiredness, or some soreness and redness in your arm - which will soon go away HPV vaccine is safe and highly effective It will give protection for at least twenty years without needing another injection Having the vaccine reduces the risk of getting cervical cancer by 90%