How to write an Award-Winning Paper Bessie Ann Young, NMRI Meeting April 19, 2013 Associate Professor University of Washington Outline of Talk • Why are papers important in academia? • Why should you write up your results • What constitutes the basic outline for a great paper? • Abstract • Introduction • Methods • Results • Discussion • Conclusions Why are papers important in academia? • Manuscripts are the “Coin of the Realm” • It allows people to see how you think and how you write • Publishing is necessary to stay in academics • Papers are necessary for promotion o If you don’t want to be promoted, don’t write any papers! • Number of papers needed varies depending on your track o Clinician educators may not need as many and can do more reviews o Physician scientists need as many as possible and they need to be in good journals with high impact factors. Why should you write up your results • If you don’t write up your results, either your mentor or someone else in your group will o or your competitor • It is a sign of productivity and accomplishment. • If your results are not written up and published, it is as if the study was never done. • It is important for your own sense of accomplishment to write up your results. • Publishing is important for grants, getting an academic position, and promotion. What constitutes the basic outline for a great paper? • IMRaD: Introduction, Methods, Results and Discussion • • • • • • • Or AIMRad Abstract Introduction Methods Results Discussion Conclusion Abstract • Sometimes the easiest to write, but sometimes the most difficult piece of the paper • Abstracts are written early for submission to meetings • Usually very structured • Can write the initial abstract but should always review after you have written the paper • Results and conclusions in the abstract should be exactly the same as those presented in the results and conclusions sections. o This is important because it may be the only part of the paper editors read prior to make a decision regarding reviewing your paper! Abstract • Background/Rationale o Why you are writing this paper and how does it contribute to the literature • Methods/materials o Clinical research-study design, populations, statistical methods used o Basic research- study design, animal vs cell culture vs other • Results o Concise and most important results o What should readers take away from this paper? • Summary o May or may not need to include in the abstract • Conclusion o Tell your audience why this piece of work is important! Common Mistakes • Abstract is too long it should be approximately 250 words • Using a meeting abstract for the manuscript o Revise the manuscript abstract accordingly • Abstract is unnecessarily complicated • Remember: The abstract is a general summary of your manuscript! • Browner, Publishing and Presenting Clinical Research Introduction: Why • Usually 3 paragraphs o Background and holes in the literature2 paragraphs o One paragraph to describe why you did your study and tentatively what you found • Briefly describe the problem and gap in the literature o Don’t describe all of the background literature here • Hypothesis, aim or goal: clearly describe what your hypothesis is and how this adds to the literature • Describe what you did and what question you answered with your study. Checklist for the Introduction • Are the four major elements present o o o o Background Existing research Problems with that research Your improvements • After reading your abstract, could someone not familiar with the field be able to describe why your study was done and how your study will improve on existing knowledge? • Use an objective tone when criticizing prior work? o They may be your reviewers! • Does your study describe how it addresses previous gaps in the literature? • W.Browner Methods: Who, What, Where and How Clinical Epidemiology or Health Services Paper • Population/subjects: describe who was in your study • Describe what type of study you conducted o o Prospective, randomized controlled trial, cohort study, cross over study Cross sectional, longitudinal study o Exposure of interest, age, sex, race o Age, sex, race, other o o o o o o Chi-squared for categorical variables Student-t test for means of continuous variables Logistic regression for a binary dichotomous outcome Linear regression for continuous outcomes Time to Event, survival or Cox models for survival Randomized controlled trial, other studies • What are your primary predictors • What are your adjustment covariates? • What is your primary outcome variable(s) • Statistical Analysis • IRB: include information on humans subject study approval Materials and Methods: Basic Research • M/M include a descriptive summary of all materials used and the methods for each experiment. • Sections should be labeled or have sub-headings possibly based on experiments • May divide into experimental design and data collection. • One section should include animal guideline compliance. • All materials should have references to place of origin. • Experiments should be written such that someone could reproduce your results if they wanted to. Results: what you found • The results section should contain results! o No interpretations, no references to other work! • Describe what you found and do not present conclusions here. • For clinical research: o Table 1 should be your demographics of your study or characteristics of study participants o Additional tables may describe additional characteristics by exposure variables or by the outcome o Last paragraphs should describe all results from multivariable or other statistical analyses. o Add figures to clarify results Results: what you found • The results section should contain results! o No interpretations, no references to other work! • Describe what you found and do not present conclusions here. • For Basic research: o Report all results. o Include tables or graphs if it makes the data clearer o Present original data gels, blots, histology Discussion: interpretation of the results Clinical Epi or Health Services • Describe briefly what you found in the first paragraph (1 paragraph). • Compare your results to what is out there in the literature (2-4 paragraphs). o Do not present a complete literature review, but keep your comments focused. o Include relevant studies • Mechanisms why do you think you found your specific results? • Limitations: list up front what the limitations of your study are or else reviewers will do it for you. o o o o Power Limited number of variables Cross-sectional data, not a randomized trial May include strengths as well Discussion: interpretation of the results Basic Research • First paragraph should interpret findings and state whether the hypothesis has been proven or rejected. • Further interpretation of results compared to the existing literature o Not a literature review • Outline conclusions o Can be a separate section of conclusions • Outline where you as the researcher intend to go next with your studies Conclusions • Outline all of your conclusions • Briefly confirm what your study found • How does your study compare to other studies in the literature • Where should the field go next? • What studies do you plan next o But don’t give too much away! Acknowledgements • Include people who helped you with the paper, but may not have contributed enough to be an author. • Make sure to include people on the paper who should be included • Each journal has criteria for authorship o JAMA has detailed criteria for authorship • Anyone acknowledged should be told Title • • • • • Start with a draft title. May want to finalize after the paper is written Needs to be interesting but not too journalistic There are several types of titles: The Description o How to write an award-winning Scientific Paper • The Topic/Description o Scientific Paper: How to write an award-winning one • The Statement o Writing an award-winning scientific paper is easy if you know how • The Question o How do you write an award-winning scientific paper? References • Use an reference library to do your literature review and add references to your paper • Examples are o Reference manager (? Is it still around) o Endnote-now with a web version you can use anywhere • They come out with new versions every couple of years that require you to learn how to use it again. • Look at the journal you are going to submit your paper to and change the references accordingly. o Follow directions. Bessie’s Rules • Give yourself time to write the paper o Block out time on your schedule • Start with an outline of your sections and fill in the blanks o IMRaD: Introduction, Methods, Results and Discussion • Start with topic sentences for your outline and you have already written a large section of the paper • “Write the paper before you start the experiment” o Write the introduction, methods, and parts of the discussion before you start the experiment • Write the paper as you do your experiments • Write a little each day if possible • Give your manuscript to your colleagues for feedback and editing • Give your mentor enough time to read the paper and respond Other Comments • Writing well does not come easy to most people • Read what you have written and revise before you give it to other people to read. • Make your sentences clear • Shorter is better (most always) • Use linking words: o However, indeed, rather, moreover, on the other hand, by contrast, in comparison, surprisingly, and consistent with… • Use the correct verb tense in each manuscript section o Introduction present tense o Methods and results past tense o Discussion past tense for your results you just presented Overcoming Writer’s Block • WB Inability to put thoughts about a project into words o Browner Many people have writer’s block. Approach systematically Make a list of what needs to be accomplished Assemble materials in a single folder or computer file • Set aside time every day to write (30minutes) • Set a goal for each day Give yourself a deadline • Write the easy sections first methods or results • • • • Summary • Manuscripts (and grants) are the academic currency; we live and die by them. • Scientific paper writing should follow a format/structure that allows for ease of writing. • Develop a strategy to allow yourself time for writing. o Give yourself deadlines for portions of the paper o Write sections of the paper Give yourself adequate time to write the paper Refer to references for style Write up your results in a timely fashion. If English is not your first language or you have difficulty with grammar, get editorial help from native speakers • Develop a thick skin • • • • Books and Style Guides Strunk and White, The Elements of Style Day R, How to write and publish a scientific paper Iverson, AMA Manuel of Style Huth, Writing and Publishing in Medicine The Economist, Style Guide Sheen, Breathing Life Into Medical Writing: a Handbook • Browner W, Publishing and Presenting Clinical Research • • • • • • References • Van Way, C. Writing a Scientific Paper. Nutrition in Clinical Practice, 2007, 22:636-640. • Alexandrov, A. How to Write a Research Paper. Cerebrovasc Disease, 2004; 18:135-38. • Pololi, Lz. Facilitating Scholarly Writing in Academic Medicine, J Gen In Medicine, 2004;19:64-68. Grammar… • “I had to re-write your paper so that I could read it!” o W. Couser • Edward Good, A Grammar Book for You and I (Oops, Me): All the Grammar You Need to Succeed in Life • “Procrastination behaviors can be attributed to a fear that the manuscript will be rejected.” • Browner