Welcome
Education, Science
and Medical
Relationships
October 21, 2013
Meeting Topics
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Introductions
Itinerary for the Day
CWRU School of Medicine Background and Vision
Science Without Borders Program
Goals for CAPES MOU and education discussion
Discussion and Q&A
Overview of CWRU
School of Medicine
Christopher D. Masotti,
CPA, MBA
Vice Dean for
Finance and Administration
School of Medicine Quick Facts
Full-Time Faculty
MD Students
PhD Students
Master Students
Employees
Revenue as % of CWRU Total
2,400
850
360
350
1,960
46%
Sources of Funds
FY14
FY11
11%
FY19 (anticipated)
12%
5%
5%
6%
11%
14%
11%
18%
74%
68%
65%
Total Revenue: $464M
Tuition Revenue: $52M
Total Revenue: $460M
Tuition Revenue: $65M
Total Revenue: $515M
Tuition Revenue: $95M
FY13 Sources of Research Funding
Federal
9%
91%
State/local govt,
foundations,
industry
School of Medicine Affiliations
•University Hospitals Case Medical Center Primary affiliate; full-time
faculty; clinical FTE employed University Hospitals Medical Group,
research SOM
•MetroHealth Medical Center Major affiliate; full-time faculty employed
by MetroHealth
•Cleveland Clinic Foundation—Cleveland Clinic Lerner College of
Medicine Full-time faculty employed by Cleveland Clinic Foundation
•Louis Stokes Veterans Affairs Medical Center Full-time faculty employed
by Veterans Affairs Medical Center
Cleveland as Healthcare Destination
• Ranked in U.S. News & World Report Honor Roll
• 1 of only 5 cities with more than one hospital on the Honor Roll
• A top healthcare destination
• Only three universities in the country with multiple affiliated
hospitals in the top rankings
• Case Western Reserve University
• Harvard University
• University of California—Los Angeles
Overarching Goals of SOM
1. Leadership in medical and graduate
education
2. Innovative and strategic research
environment
3. Meaningful community engagement and
partnerships
4. Enhanced institutional climate
http://casemed.case.edu/ora/strategicplan.cfm
From Discoveries to Cures
Medical Education
Overview
Clint W. Snyder, PhD
Interim Vice Dean for Education and
Academic Affairs
Attracting and
training the best
students
We enroll some of the nation’s
top students
Medical College Admission Test
(MCAT)
Ranked 12th in the country in MCATS
in 2012; ranked 8th in 2011
And they become even
better while they’re here
National Medical Licensing
Examination
U.S. Avg: 221
Case Western Reserve: 231
School of Medicine Education
• Primary educational program is at CWRU
School of Medicine (WR2 Curriculum)
– 165 students per year
• CWRU Cleveland Clinic Lerner College has a
separate track (CCLCM)
– 32 students per year
Foundations of
Medicine and Health
Advanced Clinical Experiences and
Residency Preparation
Basic Sciences
and
Early Clinical
Training
Core Clerkships
Acting Internships
Basic Science
Integration
Transition to
Residency
Electives and
Board Study
Advanced
Electives
USMLE Step 1
USMLE Step 2
(CK/CS)
Researchand
and Scholarship
Scholarship 
Research
MD
MDThesis
Thesis
1st Year
2nd Year
3rd Year
4th Year
Match Day 2013
Of our school’s 191 matches,
20 percent matched to top-ten hospitals
as ranked by U.S. News & World Report
• Cleveland Clinic
• Duke
• Johns Hopkins
• Massachusetts General
• UCLA
39 will stay in Cleveland:
• University Hospitals Case
Medical Center
• Cleveland Clinic
• MetroHealth Medical Center
Medical Education Opportunities
Clinical Electives:
•Sydney Medical School (Australia)
•Nanjing U Hospital Internal Medicine (China)
•Zhejiang U (China)
•FEDEPO Santa Domingo (Dominican Republic)
•Pop-Wu Medical Clinic (Guatemala)
•New OB/GYN residency (Guyana)
•Internal medicine Al-Gandhi Hospital; Hyderabad (India)
•Saitama Medical U at Saitama Medical Center (Japan)
•U of Tokyo (Japan)
•Maseno U School of Medicine (Kenya)
•Instituto Nacional de Enfermedades Respiratorias
(Mexico)
•Lamay (Peru)
•Jagellonian U (Poland)
•U of Puerto Rico (Puerto Rico)
•Baragwanath Hospital; Johannesburg (South Africa) Fogarty-Global Health mentored experience (red stars) in
•Khon Khaen U (Thailand)
Papua New Guinea/Dominican Republic/Uganda/Brazil
•St. Mary’s Hospital (Uganda)
Bioethics
•The Netherlands
•Costa Rica
•France
•Spain
•India
Inside the New Medical Education Building
• Expanded medical
education programs
• New joint programs
• Expanded Community
Health initiatives
• Separate identities and
curricula, but will share
sim center, anatomy lab,
food service, etc.
Medical Education Building
Curriculum Goals
• Future approaches to medical education
• Practical sharing between CCLCM and the University
Program
• Encouraging inter-professional education
• Multiple educational resources
• Pathways: Urban Health, World Medicine, Medical
Humanities, Business of Medicine
Campaign: Impact the
Care and Health of the
Community
•
$25 million to establish the
Weatherhead Institute for Family
Medicine and Community Health
•
Vision: to promote health and
integrate care for the whole
person and community through
research, education, leadership
and advocacy.
Vision Topic – World Medicine
The World is Shrinking
Diseases arise abroad and sweep the U.S.
AIDS
Drug resistant TB
SARS
Conversely, our scourges are exported
Metabolic syndrome
Some cancers
Vision Topic – World Medicine
– Approaches to health care differ abroad
– Strategies for delivering care in underresourced countries might inform urban
and rural health here
– Developed countries public health and
health care may inform new models for
the U.S.
– Our students may benefit from wealth of
clinical experience abroad
Graduate
Education
Overview
Paul MacDonald, PhD
Associate Dean for Graduate Education
SOM Graduate Education Office
Paul MacDonald
Martin Snyder
Robert Petersen
Monica Montano
George Dubyak
Diana Ramirez-Bergeron
Joseph Williams
Deborah Noureddine
Malana Bey
Dan Korgan
Seeds of Discovery
The Ph.D. White Lab Coat Ceremony
76 students entering 11 different programs
57 % female, 43 % male
11 different countries (33 %)
36 % from Ohio, 11 % from CWRU
Guiding Principles for Graduate Education
preparing students for success as future leaders in the rapidly
changing biomedical research environment of the 21st century.
• Interdisciplinary and collaborative
• Concept-driven and self-directed study
• Professionalism and life-long learning
• Faculty and students as colleagues
Ph.D. Graduate Programs at CWRU
Biochemistry
Tracks: RNA Biology
Structural Biology & Biophysics
Bioethics
Biomedical Engineering
Cell Biology
Epidemiology and Biostatistics
Neurosciences
Tracks: Developmental Biology
Nutrition
Pathology
Tracks: Cancer Biology
Exp. Pathology
Immunology
Mol. Cell. Basis of Disease
Molecular Medicine
Pharmacology
Tracks: Cancer Therapeutics,
Molecular Pharmacology,
Membrane Structural Biology,
Translational Therapeutics
Molecular Virology
Physiology and Biophysics
Genetics
Tracks: Developmental Biology
Molecular Biology and Microbiology
Systems Biology & Bioinformatics
SOM Ph.D. Entry Routes
1.
Biomedical Sciences Training Program – BSTP
2.
Medical Scientist Training Program – MSTP
Dual-degree – M.D./Ph.D.
3.
Direct Admission to programs
PhD: Biomedical Sciences Training Program
Students enter together,
then earn a PhD in one program
First semester: cell & molecular
biology
Lab rotations with prospective
advisors
PhD: Biomedical Sciences Training Program
Over 200 faculty
advisors
Smaller labs with
individual attention
CWRU MSTP
NIH funded Medical Scientist Training Program, 1956
2 years medical school + 4 years PhD + 2 years clerkships
Accept about a dozen students/year
90 current students and 194 graduates
AMCAS Application opens in June
Time to Degree (TTD) and Publications
2002-2007
Average TTD (years)
Average number of publications/program
Number of publications/grad
Average primary publications/program
Primary publications/grad
2008-2013
5.7
5.5
103.1
109.4
3.8
3.1
47.9
54.7
1.7
1.5
Diversification
Educational Programs
Expanded Programs
• Masters of Science in
Anesthesiology
• Masters of Science in
Medical Physiology
• Masters in Biostatistics
Upcoming Programs
• Physician Assistant (2016)
• Masters in Informatics
• Masters of Science in
Medical Education
Research Overview
and Strategy
Christopher D. Masotti,
CPA, MBA
Vice Dean for
Finance and Administration
Translating Research
from Discoveries to
Cures
•
School and its affiliated hospitals
attract $569 million in research
funds annually
•
No. 17 in the nation in NIH
research grants awarded to
medical schools
•
No. 1 in Ohio—more in NIH grants
to CWRU SOM than any other
medical school in Ohio
Research Abroad - Institutions
•Imperial College (UK)
•Institute Pasteur (France & Madagascar)
•Medical Microbiology & Parasitology,
University Hospital (Germany)
•Max Planck Institute
•Walter and Eliza Hall Institute, U Queensland,
(Australia)
•James Cook U, ICGEB (Delhi, India)
•Washington U (St. Louis)
•Notre Dame U (South Bend)
•Zhabei Health District (Shanghai)
From Discoveries to Cures
Research Areas
Malaria
Filariasis
Vector Ecology
HIV
TB
Schistosomiasis
Lymphatic Filariasis
Rift Valley Fever
Onchocerciasis
Dengue Fever
Genetics
Bioethics
Community Assessment
Collaboration . . .
is the order of the day
• Research centers and cores
– CTSC, Cancer, AIDS, Proteomics, Imaging,
Regenerative Medicine
• Institute for Computational Biology
– Case Western Reserve University
– University Hospitals Case Medical Center
– Cleveland Clinic Foundation
Economic Engine for Ohio
CWRU to receive nearly $2 million from
state to lead the Ohio Clinical Trials
Collaborative
Statewide clinical-trials platform
• Patients: quicker access to innovative treatments
• Ohio: gain edge in attracting clinical studies
Collaboration among:
• Case Western Reserve University (lead)
• Ohio State University
• University of Cincinnati
Commercialization
Drug Discovery Activities
CAHH
HTS
CTSC
TTO
5 programs
funded
25 programs
funded
6 programs
funded
4 research
incentive awards
Consulting with over 50 faculty
investigators
Marketing
Push Program
30+ programs
marketed at regular
bi-annual meetings
Translation
Gary Landreth
Kevin Cooper
Mark Chance
Hyoung-Gon Lee
Clark Distelhorst
Jerry Silver
Susann Brady-Kalnay
David Katz
Totaling over $4M
in new
investments
Key Focus Areas Driving Key Clinical Programs
SOM Investment Blueprint
• Invest in areas of interdisciplinary strength: Cancer,
Infection/Inflammation, Imaging/Structural Biology,
Visual Sciences, Cardiovascular
• Invest in emerging areas: Informatics, Translational
Neuroscience, Population and Community Health,
Genome Sciences
• Invest in high risk/high return areas: Therapeutics,
Commercialization, Metabolic Sciences
Science Without Borders Program
Professor Jorge Almeida Guimarães
President of CAPES
Goals for CAPES MOU
and
Education Discussion