A2 PRACTICAL 20
Thin layer chromatography (Technician)
You need to carry out a risk assessment before doing this practical
Apparatus
For the class
Each student needs:
• balances (0.01 g minimum resolution)
• 1 cm plastic syringes
• small sample bottle with lid to make solution
up in (5 ish cm3 volume)
• uv lamp(s)
• pestle and mortar
• capillary tubes (a few for each of the 5
tablets)
• spatula
3
• TLC plate (silica on plastic, 3 x 6 cm ish)
• chromatography tank with lid (jam jars work
well)
• gloves
Chemicals
• tablets (1 tablet per students with a similar number of each of the five types of tablet):
•
•
•
•
•
aspirin,
caffeine,
ibuprofen
paracetamol
Anadin Extra
• dichloromethane (up to 1 cm3 per student)
• ethyl ethanoate (10 cm3 per student)
Notes
• students prepare a solution of one tablet each, and then share solutions with others to provide
samples of each tablet
• the Anadin Extra box should not be visible as it shows the contents (aspirin, caffeine and
paracetamol)
• students must use capillary tubes in an exclusive way for each tablet
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23-December-2020
Chemsheets A2 1112