Cycle Design CONSTRUCTION BUILDING EFFECTIVE CYCLES This content is for entertainment and educational purposes only, and I do not make any warranties to its accuracy, applicability, or completeness. The content is not intended to be a substitute for professional medical advice. Always seek the advice of a qualified health provider. Never disregard professional medical advice or delay in seeking it because of any information presented here. I disclaim all liability to any party for direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from its use. DHT Doesn’t Aromatise Strong Binding Affinity It doesn’t Convert via 5AR Weak Anabolic due to interaction with 3-alpha hydroxysteroid dehydrogenase 19-Nortestosterone Lower Androgenic sides Weak 5AR interaction Aromatizes lower rates than testosterone Strong Anabolic Effect Testosterone Parent Male Hormone Cycle Design ALL STEROIDS DERIVED FROM TESTERONE STEROID SCIENCE STEROID FAMILY TREE LENGTH: 16-20 Weeks GOAL: Add Lean Body Mass DOSING: Start with minimum effective dose & taper up as needed. NUTRITION: Adjusted Calorie Surplus EXPECTATIONS: 5-10lbs LMB CUTTING PHASE LENGTH: 16 Weeks GOAL: Reduce Body Fat, Preserve LBM DOSING: Start with offseason cycle. Add cutting agents at 4-6 weeks in. Taper up as needed. Add orals last 4-6 weeks. NUTRITION: 500-1,000 Calorie Deficit EXPECTATIONS: 1-2 lbs fat loss per week REBOUND PHASE LENGTH: 6-8 Weeks GOAL: Rapid size gain DOSING: Drop all fat burners, orals, and tren & lower AT NUTRITION: Escalating Calorie Surplus EXPECTATIONS: Reach previous offseason weight at lower body fat % CRUISE PHASE LENGTH: 8-12 Weeks GOAL: Recover health to baseline DOSING: TRT @ 250mg per week + 2-4 units of HGH (optional) NUTRITION: Slight Deficit or Maintenance EXPECTATIONS: Some loss of hardness, fullness, and strength. Cycle Design BULKING PHASE CONSTRUCTION CYCLE PHASES 16 weeks CUTTING PHASE 16 weeks REBOUND PHASE 8 weeks CRUISE PHASE 12 weeks Cycle Design BULKING PHASE CONSTRUCTION EXAMPLE YEAR Testosterone should be the base of every bulking cycle. A.I. s are u used as needed. Primary Anabolic Equipoise or primobolan seem to be the best choice for most people Run at 70-80% of your test dose HGH Performance ennhancing effects seem to occur at 5 units or more per day. Optional Items 2nd Anabolic If tolerated, nadrolone can be run at 20-30% of the test dose as a second anabolic. Insulin For advanced users & high level competitors only, insulin can be used for improved nutrient uptake. Oral Steroids Oral steroids should be limited in use. Anadrol or Anavar pre-workout for 4-6 week durations maximum. Cycle Design Test Base CONSTRUCTION BULKING CYCLE Testosterone should be the base. Switch to test prop at the last half to allow for dosing flexibility. . Primary Anabolic Masteron or Primobolan seem to be the popular choice for most people Doses increase as test goes down. HGH Performance ennhancing effects seem to occur at 5 units or more per day. Tren If tolerated, Tren can be added to the cycle for additional body comp and fat-burning effect the last 8 weeks. Fat Burners Clenbuterol is the most common and most effective fat burner used. Oral Steroids Winstrol or Anavar are often added the last 4-6 weeks to give an additional hardening effect. Anti-Estrogens Estrogen will need to be suppressed toward the end of the cut to achieve that hard & grainy look. Arimidex is the most common choice. Cycle Design Test Base CONSTRUCTION CUTTING CYCLE Testosterone should be the base. Doses are typically lower than bulking. AIs are used as needed. Primary Anabolic Masteron or Primobolan seem to be the best choice for most people Run at 70-80% of your test dose. HGH Performance enhancing effects seem to occur at 5 units or more per day. ITEMS TO DROP ORALS: Drop all orals FAT BURNERS: Taper down fat Burners by 50% for two weeks post-cut. ANTI-ESTROGENS: Should be reduced to allow estradiol level to return to the top end of the reference range. INSULIN: Shouldn’t be needed in this phase insulin sensitivity will be high post cut. Cycle Design Test Base CONSTRUCTION REBOUND CYCLE Testosterone should be run at the high end of a replacement dose. 250-300mg per week is typical. HGH 2-4 Units per day seems to be what most bodybuilders run on a health & maintenance phase. CONSIDERATIONS GOAL: To allow your body to return to baseline and recover health. It’s Not a Cruise if: You don’t drop all other PEDs. BEFORE NEXT CYCLE: Blood panels and diagnostic testing should be at baseline health. DURATION: It typically takes 1216 weeks for health markers to return to baseline. PCT or CRUISE? Unless you are coming off for six months or more, TRT is likely more beneficial than coming off completely and crashing your hormones. Cycle Design TRT CONSTRUCTION CRUISE CYCLE HYPERTROPHY Nandrolone (mildly neuro and cardiotoxic, mental health) Primobolan (safest) Boldenone (Elavated RBC & BP) Masteron (safe) Anavar (liver and lipids) HGH (dose-dependent) DBOL (Liver, BP, Estrogen) BONE, JOINT, CONNECTIVE TISSUE HGH (dose-dependent) Nandrolone (mildly neuro and cardiotoxic, mental health) STRENGTH Anadrol (Liver and Lipids) Halotestin (Liver, Mental Health, and Lipids) Trenbolone (Kidney, Lipids, Neuro, Cardio, Mental Health) BODY COMPOSITION Trenbolone (Lipids, Neuro, Cardio, Mental Health) Masteron (Lipids) Anavar (liver and lipids) Winstrol (liver and lipids) Halotestin (Liver, Mental Health, and Lipids) Proviron (safe) HGH (dose-dependent) Cycle Design BASE HORMONE Testosterone (as high as tolerated) CONSTRUCTION COMPOUND CHOICE FAT LOSS Clenbuterol (heart & blood pressure) T3 (thyroid) Caffeine (B.P.) Yohimbine (heart) Ephedrine (heart, Anxiety & BP) Trenbolone (Lipids, Neuro, Cardio, Mental Health) DNP - NO GO - Death GLUCOCORTICOID SUPPRESSION Trenbolone (Kidney, Lipids, Neuro, Cardio, Mental Health) ESTROGEN CONTROL Anastrozole (lipids, joint, and bone) Letrozole (lipids, joint, and bone) Exemestane (lipids, joint, and bone) Nolvadex (clotting & bone) BLOOD PRESSURE CONTROL ACE inhibitors (cough) ARBs (hyperkalemia & water retention) Calcium Channel Blockers (affect muscle contractions) Beta Blockers (limits fat loss) SOFT TISSUE REPAIR BPC 157 TB-500 Cycle Design NUTRIENT UPTAKE Berberine Metformin (gastric distress, low glucose) Insulin (Hypoglycemia, DEATH.) CONSTRUCTION COMPOUND CHOICE LOW ESTROGEN SYMPTOMS Decreased libido Fatigue and low energy levels Mood swings and irritability Hot flashes or night sweats Memory and cognitive issues Joint pain or stiffness NORMAL ESTRADIOL LEVELS IN MEN 10 to 40 picograms per milliliter (pg/mL) Treating High Estrogen: When side effects present themselves Adjust Test to DHT ratios Add Aromatase inhibitor at a minimum effective dose AROMATASE INHIBITOR: A medication that blocks the action of the aromatase enzyme, lowering the conversion of testosterone to estrogen. Anastrozole (Arimidex) = 1 mg dose Letrozole (Femara) = 2.5 mg dose Exemestane (Aromasin) = 25 mg dose Suicide Inhibitor (inactivates aromatase enzyme) Selective Estrogen Receptor Modulator (SERM): Either blocks or activates estrogen receptors in different tissues. SERMs are unique because they have the ability to act as estrogen receptor agonists (activators) in some tissues while acting as antagonists (blockers) in others. Tamoxifen: It acts as an estrogen receptor antagonist in breast tissue but can have agonist effects in other tissues. Raloxifene (Evista): It acts as an agonist in bone tissue but as an antagonist in breast tissue. Clomiphene (Clomid): It acts as an antagonist in the hypothalamus. Cycle Design HIGH ESTROGEN SYMPTOMS Erectile Dysfunction Bloating & Water Retention High Blood Pressure Unexplained Fat Accumulation Depression & Anxiety Acne Flareups Gyno Prostate Inflammation SIDE EFFECTS ESTROGEN MANAGEMENT Cycle Design WATER RETENTION High Estrogen Androgen Stimulation of RAAS HGH ERECTILE DYSFUNCTION High Estrogen Tren Deca & NPP LOW SEX DRIVE Low Estrogen ACHY JOINTS Low Estrogen Overuse of AIs HIGH BLOOD PRESSURE Water retention Overuse of Stims Excessively Elevated RBC, Hemoglobin Hematocrit PROSTATE INFLAMMATION High Estrogen High DHT Stimulant Abuse ACNE High Estrogen High DHT Ratio of DHT/Estrogen INSOMNIA Tren Overuse of Stimulants & Fat Burners ACID REFLUX Overuse of Orals Tren LOW HDL Overuse of Orals Low Estrogen Overuse of AIs NUMB HANDS Overuse of HGH POOR MOOD (Anxiety, Anger, Depression) High Estrogen Tren & NPP EXCESSIVELY ELEVATED RBC, HEMOGLOBIN & HEMATOCRIT Overuse of EQ EPO Overuse of Anadrol SIDE EFFECTS PED SIDE EFFECT CAUSES What It Is & How It Works: Peptide hormone is produced by pancreatic beta cells. It consists of 51 amino acids and was the first peptide hormone discovered. Regulates glucose, fat, and amino acid metabolism, signaling their absorption into the liver, muscle cells, and fat stores. HGH and Insulin Counter-Regulatory Nature: Insulin optimizes anabolic effects of HGH and inhibits its fat-mobilizing properties. Combined GH and insulin increase net protein balance more than insulin alone. Bodybuilders use insulin for anabolism to promote protein synthesis and glycogen storage. Cycle Design INSULIN FACTS Monitoring blood sugar levels is essential for safety and health. Measure your glucose levels periodically to ensure proper glucose levels. HYPOGLYCEMIA SYMPTOMS Shakiness Fast pulse Hunger Sweating Nervousness Cycle Design BLOOD SUGAR MONITORING Insulin Aspart (Novolog) Onset: 0.2-0.3 hours Peak Glycemic Effect: 30-90 min Duration: 3-5 hours Insulin Glulisine (Apidra) Onset: 0.2-0.5 hours Peak Glycemic Effect: 30-90 min Duration: 3-4 hours Insulin (oral inhalation - Afrezza) Onset: 0.25 hours Peak Glycemic Effect: 1 hour Duration: 2.5-3 hours Cycle Design Insulin Lispro (Humalog) Onset: 0.25-0.5 hours Peak Glycemic Effect: 30-90 min Duration: ≤ 5 hours PROFILES RAPID INSULINS Insulin regular (Humulin R, Novolin R) Onset: 0.5-1 hours Peak Glycemic Effect: 2.5-5 hours (U-500 → 4-8) Duration: 5-8 hours (U-500 → 1324) Cycle Design (REGULAR) PROFILES SHORT INSULINS Insulin Degludec (Tresiba) Onset: 30-90 min Peak Glycemic Effect: none Duration: 42 hours Insulin Detemir (Levemir) Onset: 1-2 hours Peak Glycemic Effect: 6-8 hours Duration: 24 hours Insulin Glargine (Basaglar, Lantus) Onset: 3-6 hours Peak Glycemic Effect: None Duration: 20-26 hours Cycle Design (BASAL) PROFILES LONG INSULINS Insulin Aspart protamine suspension + Insulin Aspart (Novolog Mix 70/30) Onset: 0.17-0.33 hours Peak Glycemic Effect: 1-4 hours Duration: 18-24 hours Insulin Lispro protamine + Insulin Lispro (Humalog Mix 75/25) Onset: 0.25-0.5 hours Peak Glycemic Effect: 1-6.5 hours Duration: 14-24 hours Insulin NPH + Insulin Regular (Novolin 70/30) Onset: 0.5 hours Peak Glycemic Effect: 2-12 hours Duration: 18-24 hours Cycle Design Insulin Aspart + Insulin Degludec (Ryzodeg 70/30) Onset: 0.23 hours Peak Glycemic Effect: 2.3 hours Duration: > 24 hours PROFILES COMBO INSULINS Properties: Testosterone converts to Estrogen (20% avg, via aromatase) and DHT (10% avg, via 5AR), and this conversion is influenced by genetics and body fat. Androgenic: Masculinization (body hair, voice deepening, sex organ development, aggression, libido). Anabolic: Increased protein synthesis, improved body composition, bone remodeling, muscle anabolism (Anabolic and Androgenic rating 100). Mechanism: Lock & Key System: Free Testosterone in the bloodstream binds to cellular receptors in muscle, skin, scalp, kidney, bone, prostate, CNS, activating genetic responses. Performance Benefits: Increased protein synthesis, recovery, body composition, anti-catabolic effects, and redblood cell count. Side Effects: Shutdown of natural testosterone, testicular atrophy, gynecomastia (due to high estrogen), high blood pressure (caused by estrogen, diet, or androgens), bloating, worsened lipid profile, acne, BPH, prostate cancer, baldness (due to high DHT). Doses & Cycles: TRT: 100-200 mg/week, perpetual. First-Time Growth Cycle: 300-500 mg/week, 1012 weeks, AI if necessary. Typical Gym Bro Cycle: 500-1,000 mg/week, stacked with one anabolic, AI/SARM if needed. Competitor Offseason Cycle: 1,000+ mg/week, stacked with multiple anabolics, AI/SERM. Cycle Design TESTOSTERONE PROFILES STEROID PROFILE Injectable Form: Dosage: The common dosage range for BPC157 when used in an injectable form is between 200 mcg to 500 mcg per day. Frequency: It is typically administered once or twice daily, depending on the severity of the condition being treated and the individual’s response. Duration: The duration of use can vary, but a typical course might last between 2 to 4 weeks. Some protocols suggest continuing until the injury or issue has significantly improved Administration: Subcutaneous Injection: BPC 157 is commonly administered through subcutaneous injections (under the skin), which is thought to be more effective for systemic or localized healing, particularly for muscle or tendon injuries. Intramuscular Injection: This method involves injecting BPC 157 directly into the muscle near the site of injury. It's believed to provide more direct healing effects on the specific area. Oral Form: Dosage: For oral administration, doses are generally higher due to reduced bioavailability. A common dosage range is 500 mcg to 1,000 mcg per day. Frequency: This is often taken once daily. Duration: Similar to the injectable form, the duration may range from 2 to 4 Cycle Design BPC157: PROFILES HEALING PEPTIDES TB500: Loading Phase: Dosage: During the initial phase, a common dosing protocol involves 4 mg to 8 mg per week. Frequency: This dosage is typically divided into two injections per week (e.g., 2 mg to 4 mg per injection). Duration: The loading phase usually lasts 4 to 6 weeks, depending on the severity of the condition being treated and the individual’s response. Maintenance Phase: Dosage: After the loading phase, the dosage is often reduced to 2 mg to 4 mg per week. Frequency: This can be administered in a single weekly injection or divided into two injections, depending on preference and response. Duration: The maintenance phase can continue for several weeks to months, depending on the ongoing needs for injury prevention and recovery support. Administration of TB-500: Injection Site: TB500 is typically administered via subcutaneous or intramuscular injection. Some users may choose to inject near the site of injury, although systemic administration is also effective. Cycle Design TB500: PROFILES HEALING PEPTIDES Properties: Structurally Altered Testosterone Double bond at Carbons 1 and 2 reduces androgenic effects Weaker androgen receptor binding, strong anabolic Methyl group at 17th carbon allows oral administration (liver toxic) Strong estrogenic effects (converts to methyl estradiol) Promotes lean tissue gain, mild androgenic effects Effects: Increased protein synthesis and nitrogen retention Fast size gain (mostly water) Side Effects: Strong estrogenic: Bloating, Gyno, High blood pressure Mild androgenic: Body hair growth, Baldness, BPH, Acne, Masculinization in women Suppresses HDL, raises LDL Suppresses HTPA at doses as low as 10 mg/day Mild suppression of natural testosterone Liver toxic at higher doses (>15 mg/day) Applications: Quick strength and size increases Boosts explosive activity Half-Life: 3-5 hours Cycles & Doses: Beginner: 10-15 mg/day Intermediate: 15-50 mg/day Advanced: 50+ mg/day Personal Experience: Side effects at 50 mg: Gyno, high blood pressure, severe pumps, appetite suppression, ankle swelling Explosive strength gains, but mostly water and lost after stopping Pre-workout use: Small doses (10-15 mg) for pumps, not suitable for deadlifts/squats Prefer other options like Anavar 90% respond poorly, 10% respond well Cycle Design DBOL (Methandrostenolone) PROFILES STEROID PROFILE Properties: Structurally altered form of testosterone Double bond between Carbons 1 and 2 reduces estrogenic activity (50% of testosterone rate) Same anabolic properties as testosterone Lower androgenic properties than testosterone No progestogenic activity Reduces to DHB (potent androgen), not DHT Effects: Increased protein synthesis and nitrogen retention Increased IGF-1 production Increased red blood cell count Inhibition of glucocorticoids (stress hormones) Increased appetite Side Effects: Elevated RBC/hematocrit (varies by individual) Androgenic side effects (Body hair growth, Baldness, BPH, Acne) Suppresses testosterone production Possibly kidney toxic Applications: Bulking Increased appetite, strength gains, size gains Undecylenate Ester: 14-day half-life Detectable up to a year after use Cycles & Doses: Beginner: 300-500 mg per week Intermediate: 500-800 mg per week Advanced: 900+ mg per week My Experience: Low side effects, a feeling of overall wellness Can lower estrogen Strength and size increases, but not as much as nandrolone Elevated hematocrit Used for hypertrophy cycles, not fat loss phases (though some do) Cycle Design Equipoise (Boldenone Undecylenate) PROFILES STEROID PROFILE Properties of Halo: Structurally altered testosterone Added fluoro group at carbon 9 and 3 and beta-hydroxyl group at carbon 11 Non-aromatizing, strong androgenic action Moderate anabolic action Methyl group at 17th carbon allows oral administration More potent androgen than testosterone Effects of Halo: Increased protein synthesis, nitrogen retention, bone density, healing Reduces glucocorticoids Increased strength, definition, & modest size increases Reduces breast tissue Side Effects of Halo: Liver toxic Strong negative effect on lipids Elevated RBC/hematocrit (varies by individual) Androgenic side effects: Suppresses testosterone production Applications for Halo: Peaking for bodybuilding shows: (hardness & fullness) Peaking for powerlifting: (aggression & strength) Half-Life: 9-hour half-life, take twice per day Cycles & Doses: Beginner: 10 mg/day Intermediate: 20 mg/day Advanced: 20+ mg/day Cycle Length: Serious liver effects if used more than 2 weeks, 6 weeks max My Thoughts: Excellent for peaking for a show Avoid if prone to temper issues (can cause extreme aggression) Personally experiences euphoria, not anger Recommended only for peaking (2-3 weeks) Cycle Design Halotestin (Fluoxymesterone) PROFILES STEROID PROFILE Properties of Nandrolone (Deca / NPP): 19-nortestosterone (19-nor) anabolic steroid Lacks carbon atom at the 19th position Strong anabolic properties Weak androgenic properties Effects of Nandrolone: Increased protein synthesis, nitrogen retention, IGF-1 production Increased red blood cell count Inhibition of glucocorticoids (stress hormones) Increased bone mineral content and collagen synthesis Side Effects of Nandrolone: Up-regulates aromatase expression Potential Sexual dysfunction Strong binding affinity with the progesterone receptor (potential gyno in prone individuals) Worse effects when combined with highly aromatizing steroids Affects dopamine response causing potential mood issues Applications for Nandrolone: Increases size Alleviates joint pain Improves strength Common Esters: Nandrolone Decanoate (Deca): Half-life: 16-12 days Nandrolone Phenylpropionate (NPP): Half-life: 4.5 days Cycles & Doses: Beginner Dose: 200-300 mg per week Intermediate Dose: 300-600 mg per week Advanced Dose: 600+ mg per week My Experience: Increases strength and size Joints feel great Side Effects Experienced: Erectile dysfunction at higher dosesAnxiety, gyno issues, water retention, increased blood pressure Cycle Design Nandrolone (Deca / NPP) PROFILES STEROID PROFILE Properties of Tren Is a 19-nortestosterone (19-nor) anabolic steroid Double Bonds at the Carbons 9 & 11 Inhibits aromatization, Increases androgen receptor binding affinity, and slows its metabolism Effects of Tren Increased protein synthesis & nitrogen retention Increased IGF-1 production Inhibition of Glucocorticoids (stress hormones) Strong Anti-Catabolic Increased Feed Efficiency (Eat less and Maintain Muscle) Side Effects of Tren Strong binding affinity with the progesterone receptor This can lead to gyno in prone individuals Strong Androgenic Side Effects (Aggression, Hair Loss, Body Hair Growth, Prostate Enlargement) CNS stimulation (Insomnia, acid reflux) Applications for Tren Great for dieting Eat less while maintaining muscle mass Prevents muscle loss from while dieting Promotes a dry & hard look In Some specific situations can be used for busting bulking plateaus Common Esters Tren Enanthate - Half Life = 6-10 Days Tren Acetate - Half Life = 3 Day Ten Hex (Parabolan) Half-Life = 8-10 days Cycles & Doses Beginner Dose 100-150 mg per week Intermediate Dose 150-300 mg per week Advanced Dose 300 mg+ per week My Experience Nasty Side Effects Doses north of 300mg per week have crazy side effects. I feel like shit. Hair Loss BPH Terrible Insomnia Anxiety & Apathy Cycle Design Trenbolone PROFILES STEROID PROFILE Properties of Masteron Is a structurally altered form of DHT Changed by the addition of a methyl group at the carbon 2 position Protects it from metabolic breakdown by the 3hydroxysteroid dehydrogenase enzyme, which is found in the skeletal muscle like DHT Strong binding affinity No measurable estrogenic effects Moderate androgenic effects Moderate anabolic effects Released in 1969 as a breast cancer treatment Effects of Masteron Moderate increase protein synthesis & nitrogen retention Moderate suppression of estrogen Hardening effect Side Effects of Masteron Moderate to Low Risk of Androgenic Side Effects Impacts lipids negatively Suppresses natural testosterone production Half-Life Propionate Ester has 2 days Enanthate Ester has 7-9 days Applications for Masteron Great for Fat Loss Phases No progesterone-like or estrogenic sides It seems to have a direct effect on improved body composition Less Than Optimal in Hypertrophy Phases Cycles & Doses Masteron is weaker than other steroids and might require higher doses for similar effects Beginner Dose 200-300 mg per week Intermediate Dose 300-700 mg per week Advanced Dose 700 mg+ per week My Experience No Notable Side Effects Hardens me up Improved Sex Drive Reduced my gyno (tightened up my chest fat) Seems to help get rid of estrogenic fat Didn’t find that it contributes much to offseason size Cycle Design Masteron (Drostanolone Propionate) PROFILES STEROID PROFILE Properties of Primobolan: Structurally altered form of DHT Double bond between Carbons 1 and 2, additional 1methyl-group Protects against hepatic metabolism No measurable estrogenic effects, very mild androgenic effects Considered the safest anabolic Has a 7-9 day half-life Effects of Primo: Increase in protein synthesis, nitrogen retention, IGF-1 production, and red blood cell count Side Effects of Primo: Reputation as the safest steroid Very slight risk of androgenic side effects: Body hair growth, baldness, BPH, acne Mildly suppresses natural testosterone production Increased RBC and hematocrit Mild increase in liver enzymes Applications for Primo: Mass Phases: Increased nitrogen retention, no estrogenic sides Lowers estrogen conversion of testosterone (enhances testosterone effectiveness) Improves body composition directly Cutting Phases: Lowers estrogen, and keeps you full Cycles & Doses: Beginner: 300-500 mg per week Intermediate: 500-800 mg per week Advanced: 1 gram+ per week My Experience: No side effects, the feeling of overall wellness Strong impact on lowering estradiol, perfect BP, slightly elevated hematocrit Best blood results on test and primo Expensive but safe and worth it if health is a priority High doses are required for noticeable results Can be faked; new favorite offseason primary anabolic Cycle Design Primobolan (Methenolone Enanthate) PROFILES STEROID PROFILE Properties of Anavar: Structurally altered form of DHT Added oxygen atom replacing carbon-2 in the A-ring Strong anabolic due to this modification Methyl group at 17th carbon allows oral administration (C17-aa, liver toxic) No measurable estrogenic or progestin-like effects Effects of Anavar: Increased protein synthesis, nitrogen retention, decreased SHBG, increased IGF-1 production, increased red blood cell count Reduces thyroid binding globulin Anecdotal belief it may increase fat-burning Inhibition of glucocorticoids (stress hormones) Strong anabolic action Side Effects of Anavar: Mild compared to other steroids Can elevate RBC/hematocrit (varies by individual) Low risk of androgenic side effects Suppresses HDL Mild suppression of natural testosterone production C17-alpha alkylated (liver toxic at higher doses/durations) Less liver toxic than other C17-AA steroids Studies showed that: No liver toxicity at 20 mg/day 40 mg/day: 30-40% increase in liver enzymes 80 mg/day: 80% increase in liver enzymes Applications for Anavar: Fat Loss Phases: Increased nitrogen retention, no estrogenic sides, suppresses cortisol Anecdotal evidence of indirect effect on lipolysis Promotes muscle retention in a caloric deficit Hypertrophy Phases: High anabolic properties, can be stacked for increased effect Promotes strength increases Anavar Half-Life: 9-13 hours Cycles & Doses: Beginner: 20-30 mg/day Intermediate: 40-50 mg/day Advanced: 50+ mg/day My Experience: Moderate side effects at 50 mg/day (elevated liver enzymes, suppressed appetite) No notable androgenic side effects Hardens and makes veins more visible, increases strength Usage: Last 6-8 weeks of prep Occasional pre-workout in the offseason for strength Cycle Design Anavar (Oxandrolone) PROFILES STEROID PROFILE Properties of Winstrol Is a structurally altered form of DHT Introduction of an attached pyrazol group at the A-ring of the hormone replacing the 3-keto group. Modification makes it a very strong anabolic while reducing androgenic effects. Modification at the 17th carbon position by the addition of a methyl group allows oral administration. No measurable estrogenic effects Very mild androgenic effects Both oral and injectable are C17-aa Effects of Winstrol Increased protein synthesis and nitrogen retention Decreased SHBG (50% reduction) Moderate Increase in Red Blood Cell Count indirectly affects glucocorticoids and mineralocorticoids Strong Anabolic Action Side Effects of Winstrol Can Elevate RBC/ Hematocrit Risk of Androgenic Side Effects (known for hair loss) Skewed Lipids Study showed a 6mg daily dose for 6 weeks caused: 33% decrease in HDL 29% increase in LDL Suppresses Natural Test Production Joint Pain C17 - alpha alkylated and can be liver toxic at higher doses/durations Decreases telomerase activity causing liver aging Applications for Winstrol Contest Prep - great for drying out Winstrol Half-Life 8 hour half-life Cycles & Doses Beginner Dose 25 mg per day Intermediate Dose 50 mg per day Advanced Dose 100+ mg per day My Experience Blew up my liver enzymes as much as Anadrol Hardens me & dries me out instantly on as little as 25mg Terrible Joint Pain & cramps Crushed my appetite Only consider it for the end of prep Cycle Design Winstrol (Stanozolol) PROFILES STEROID PROFILE Properties of Anadrol Is a structurally altered form of DHT A 2-hydroxymethylene group is attached to a carbon in the first cycloalkane ring The modification makes it a very strong anabolic, whereas DHT is not Modification at the 17th carbon position by the addition of a methyl group allows oral administration Very potent anabolic Moderate androgenic effects Effects of Anadrol Increased protein synthesis & nitrogen retention Increased IGF-1 production Strong Increase in Red Blood Cell Count Strong Anabolic Action Strong non-genomic effects (CNS Drive) Side Effects of Anadrol Worst at Elevating in RBC/ Hematocrit Strong estrogenic side effects while it doesn’t reduce to estrogen Strong Appetite reduction Moderate Androgenic Side Effects Crushes Lipids - 50mg dose in study lowered HDL by 23pts in 12 weeks Bloating & Water Retention Increased Blood Pressure Mild suppression of natural testosterone production Very liver toxic Limited evidence that it can cause liver cancer Applications for Anadrol Great for Quick Strength & Size Gains Powerlifters looking to peak Situations where quick size is needed in explosive sports Can be used in Hypertrophy phases Can be used on show day for fullness Anadrol Half-Life 16 hour half life Cycles & Doses Beginner Dose 50 mg per day Intermediate Dose 50-100 mg per day Advanced Dose 100+ mg per day My Experience Strong Side Effects. It it me hard Loss of appetite Flared up my gyno badly Blood pressure went through the roof Made me big and strong I blew up 20lbs in a few weeks and got strong and big I love it but would limit its use. Not worth it for non-competitors Cycle Design Anadrol (Oxymetholone) PROFILES STEROID PROFILE Properties Stimulates growth, cell reproduction, and cell regeneration Increases protein synthesis Enhances muscle growth Promotes fat metabolism Effects Increases muscle mass Reduces body fat Improves exercise performance Enhances bone density Accelerates tissue repair Side Effects Joint and muscle pain Edema (swelling) Carpal tunnel syndrome Insulin resistance Increased risk of diabetes Potential contribution to cancer growth Bodybuilding Uses Promotes muscle hypertrophy Accelerates recovery from intense workouts Enhances fat loss Improves overall body composition Half-Life Approximately 2-3 hours (active biological effect can last longer) Doses Varies based on goals: therapeutic vs. performance enhancement Replacement Dose: 2-4 IUs per day Typical bodybuilding dose: 5-18 IU per day Personal Experience (Hypothetical Example) Increased muscle mass and strength Faster recovery times Tiredness and hands numb at higher doses Cycle Design HGH (Human Growth Hormone) Profile Full Name: Somatropin Type: Peptide hormone Produced by: Pituitary gland Structure: 191 amino acids PROFILES HGH PROFILE
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