Study of all elements and their compounds except CARBON and its compounds. Non living matter and minerals found on earth The distinction between the organic and inorganic are not absolute ,but there is much overlap. It has many applications in every aspect of pharmacy including catalysis in drug synthesis, pigments, surfactants and agriculture BRANCHES COORDINATION CHEMISTRY BIOINORGANIC ORGANOMETALLIC COMPOUNDS SYNTHETIC INORGANIC CHEMISTRY. INORGANIC COMPOUNDS Berzelius, the 19th century chemist , described inorganic compounds are inanimate. The first important synthetic inorganic compound was ammonium nitrate for soil fertilization. These are synthesized for use as drugs such as cisplatin, magnesium hydroxide etc. Some of the compounds are used as catalysts and reagents in organic chemistry. Ex: lithium aluminium hydride. Sources of inorganic compounds : Derived from either organic or inorganic sources . Many drugs are from plant and synthetic sources. Definition : Study of pharmaceutical applications of the inorganic compounds led to the establishment of a new avenue called pharmaceutical inorganic chemistry. It deals with the study of preparation, standards of purity, limit test for determining quality ,purity and storage conditions of all inorganic compounds. Importance of inorganic pharmaceuticals : Inorganic pharmaceuticals are useful in the following ways : Useful medicinally for their therapeutic purpose . Ex: Astringents and antimicrobials etc. Pharmaceutical aids. Ex: Bentonite , talc etc. Replenishing the normal content of body fluids. ExSodium, potassium, calcium, chloride etc. Used in pharmaceutical analysis . Ex – Titrants such as potassium permanganate etc. Applications in pharmacy as follows : Abrasives – Dibasic calcium phosphate . Absorbents – Calcium carbonate . Acidifiers – dil. Hydrochloric acid . Adsorbents – Bismuth subnitrate . Alkalizers - Sodium citrate . Anaesthetics – Nitrous oxide . Analgesic – Nitrous oxide . Antacids – Caco3 . Anthelmintics – Ammoniated mercury.
