June 17, 2014 Learning from Market Research Programme (ME Brand) Period: 9th to 14th June’14 Areas covered: Karawal Nagar, Bhajan Pura, Yamuna Vihar, Seelampur No. of Chemists covered: 27 =================================================================== Learning pertaining to Direct Competition: Nurokind Plus /Mahagaba-M (Mankind) are the major moving brands in the region. Meganeruon-OD Plus (Aristo), Pregeb-M (Torrent) & Neugaba-M (Sun) are the other top brands. The sales of major Mecobalamin (1500 mcg comb.) brands vary from 3-20 strips/week & that of Mecobalamin (750) +Pregabalin (75) combination is 3-15 strips/week in the region. In plain Mecobalamin injections, Methycobal (Wockhardt) & Nurokind (Mankind) are the other major brands. (in the range of 5-70 Amp./Week) Scheme of 4+1 is available in Nurokind Inj (Mankind) though no scheme is available on Methycobal inj (Wockhardt). However, there are some brands in ME-PR (Mecobalamin 750 mcg + Pregabalin 75 mg) market i.e. Pregamal (Austro Labs-Delhi) & Pregabel-M (Knoll Pharma-Mumbai) are offering scheme (5+1). The leading chemists maintain higher inventory compared to other chemists. The observation regarding Nurokind Plus (Mankind) /Pregeb-M (Torrent) /Methycobal inj (Wockhardt) being the major brands in the region, coincides with the Pharmatrac report (Feb’14) as well according to which above mentioned brands are the no. 1 unit wise selling in Delhi in their respective categories. Learning pertaining to Indirect Competition/Other Combinations: Plain Gabapentin is also prescribed in Neuropathic pain (300mg) & sometimes Mecobalamin + Pregabalin combination are also preferred in Neuropathic conditions associated with pain & Average prescription duration remains OD/BD dosage for 1-3 Mths. Major brands: Gabapin (Intas) / Gabata Plus (Alkem) Brand Company Compostion MRP/Tab/Cap Gabapin Intas Gabapentin 300 mg Capsules 12.40 Gabata Plus Alkem Gabapentin 300 mg+ Methylcobalamin 500 mcg Tablets 12.00 Learning pertaining to the Brand/Molecules: As per the chemists’ feedbacks, the prescription% of Mecobalamin combinations is more than the Pregabalin combination; however the difference is not much. Neuropathic conditions & associated pain are the major indications that contribute majorly to the prescriptions of Mecobalamin & its combinations. The dosage/Rx duration of Mecobalamin (plus comb), Mecobalamin + Pregabalin (MEPR comb) & Mecobalamin inj respectively are as follow: Mecobalamin comb: OD 2-4 week in Neuropathy (may go upto 6 mths as shared by Chemist) Mecobalamin + Pregabalin (ME-PR comb): OD/BD 1-4 week (may go upto 3 mths) in Neuropathic Pain. Mecobalamin 500 mcg inj.: OD Alternate Day (3-5 Amp. week up to 3 weeks) in Neuropathy. 1500 mcg Inj. Once Weekly for 2-3 Weeks. As per Chemist, in some prescriptions Dermat prescribe plain Pregabalin combinations for OD/BD for up to 2-6 Weeks in Post Herpetic Neuralgia cases, though the prevalence of such prescriptions is less in the region. Majorly co-prescribed drugs involve Analgesics (Diclofenac, Aceclofenac, Etoricoxib), Anti-ulcers (PPIs, PPIs + Domperidone, H2 Blockers), Anti Diabetics (e.g., Glimipiride, Metformin etc.) & Anti Hypertensives (Amlodipine, Temisartan, Losartan etc.) Majority of the prescriptions are coming from GPs/Cons Physicians, however Orthos also contribute majorly to the prescriptions. 10’s pack is prevalent in majority of the oral formulation, only Pregalin-M (Torrent) is having 15’s pack. In Injections, the major selling brands ie., Methycobal & Nurokind are available in 4 amp. Pack, however the inj. Like Meganeuron, Rejunex, Nervup are having single amp in monocarton. Besides, local Nursing homes the major share of the prescriptions are cominf from floating prescriptions.(from Govt./Pvt Hospitals eg., GB Pant, LNJP, GTB, AIIMS, Aruna Asaf Ali, Hindu Rao, St. Stephen’s etc.) Learning pertaining to ME-PXL formulation: The combination of ME-PXL is not moving well in the region. However, one or two doctors started writing the combination as shared by one of the chemist. (e.g, ME-PXL by Dr. Sandeep Sharma (Phy)-Roopali Nursing Home) The sales are low for this combination in the range of 3-5 strips/week only at selected leading counters for selected brands. The dosage for the combination is 1 – 3 mths OD. Major prescriptions are from Physicians. Pregastar M OD (Lupin) & Pregeb M OD 75 (Torrent) are the only moving brands The Prescriptions of ME-PXL is coming at one/two leading chemists. (2-3/Week) Learning pertaining to Prescribers: The prescriptions for Meganeuron-OD Plus (Aristo), Nervup OD (Abbott), Matilda Forte (Lupin), Pregeb-M (Torrent) are majorly contributed by Consulting Physicians however the same of Nurokind Plus (Mankind), Mecobal Plus (Rapross), Mahagaba-M (Mankind) are coming from General Physicians.