A POWERPOINT PRESENTATION ON OBSESSIVE-COMPULSIVE DISORDER (OCD) OBJECTIVE Medical/ Nursing Management Pathophy siology Types signs and symptoms Definition of OCD ■ OCD is a mental health disorder, characterized by distressing unpleasant thoughts or images (obsessions ) and by repetitive unwanted actions (compulsions ). Though obsessions increase anxiety, they are not simple real-life worries. The consequent compulsion may serve to decrease or increase the individual’s anxiety ( Gargano et al.,2023). WHAT IS OCD? Types of obsessive-compulsive Disorder 1) Contamination- occurs due to severe fear of contracting diseases causing the sufferer to wash oneself and their environment to a harmful degree excessively. 4)Intrusive thoughts; Sufferers are affected by disturbing thoughts and can be concerned with any topic. 5) Ruminations; the individual is involved in a sustained chain of thoughts on an unproductive topic. 2)Aggressive and somatic obsessions with checking compulsion; common with people riddled with anxiety They engaged in checking compulsion for hours at a time. 3) Hoarding obsession with collecting compulsion; homes are littered with unwanted old and countless items om, 2024). (Theanxiety.c SYMPTOMS OF OCD OBSESSIVE THOUGHTS Fear of being contaminated by germs Excessive worries with tidiness and symmetry Excessive concerns about religious issues, illness, or morality Disturbing intrusive thoughts ■ COMPULSIVE BEHAVIORS ■ Obsessive washing and cleaning. ■ Placement of objects in patterns using rigid rules ■ Extreme double-checking of appliances, locks, and safety measures. ■ tapping, word repetitions, and counting ■ (Gargano et al.,2023) PATHOPHYSIOLOGY OF OCD BIOLOGICAL DIAMENTION ■ Hereditary is associated with OCD Multipath Model Of OCD ■ Significant risk found in firstdegree relatives ■ OCD can manifest due to poor development of the fetal brain. associated with environmentally based biological factors such as; smoking in pregnancy. (Sue et al.,2022). • Several cortical and subcortical regions such as the orbitofrontal cortex Parts of the brain affected in OCD • Dorsolateral prefrontal cortex • Amygdala • Head of the caudate nucleus • Thalamus Serotonin (neurotransmitter) (Gargano et al., 2023) This Photo by Unknown Author is licensed under CC BY-SA IRREGULARITY IN THE BRAIN AND OCD ■OCD acts on the cognitive functions of the brain linked with executive functioning 1) Impaired planning and decision making 2) difficulty shifting attention away from intrusive thoughts/ compulsive behaviors DYSFUNCTION IN THE PREFRONTAL CORTEX Orbitofrontal Cortex (OFC): The OFC involves decision-making, emotional processing, and reward evaluation. Dysfunction within the OFC may result in difficulties in assessing the significance of stimuli and lead to repetitive, compulsive behaviors aimed at decreasing perceived threats. Anterior Cingulate Cortex (ACC): The ACC plays a role in error detection, conflict monitoring, and emotional regulation. Hyperactivity in the ACC can amplify feelings of uncertainty and distress, reinforcing obsessive thought patterns and compulsive rituals. Impact of Prefrontal Cortex Dysfunction on Cognitive Processes and Obsession Generation Decision-Making: Hyperactivity in the prefrontal cortex can impair decision-making processes, leading individuals with OCD to interpret neutral stimuli as threatening and prioritize avoidance behaviors. Emotional Regulation: Dysregulation within the prefrontal cortex affects emotional processing, resulting in heightened anxiety and an inability to effectively regulate emotional responses to intrusive thoughts. Abnormalities in Basal Ganglia(caudate nucleus and putamen) Dysfunctional Basal ganglia Normal Basal Ganglia →Regulate motor function I. Difficulty inhibiting unwanted motor actions/perceived behaviours Habit formation II. Disrupt the balance of neurotransmitters and neural Procedural learning signaling within the basal ganglia circuits Stores automatic behaviors like washing and grooming III. contributing to the manifestation of OCD symptoms. Disfunction in the Basal Ganglia Contd. Hyperactivity in the basal ganglia may contribute to the reinforcement of repetitive actions and rituals characteristic of OCD. Additionally, it can disrupt the inhibitory control mechanisms that normally suppress compulsive behaviors, leading to their persistence despite efforts to resist them. Understanding the role of basal ganglia abnormalities in OCD highlights the importance of targeting this brain region in the development of effective therapeutic interventions. (Stein et al., 2015) SEROTONIN THEORY A range of studies points to the role of the serotonin system in mediating OCD. Serotonin is a naturally occurring neurotransmitter that carries signals between nerve cells and around the body. It plays important roles such as learning, memory, happiness, sleep as well as mood and emotions. Low serotonin levels in the brain trigger someone with OCD to become nervous and more alert to stimuli than normal in their behaviors causing compulsive behaviors such as extreme hand washing, counting, or organizing. Serotonin imbalance is a significant factor in the pathophysiology of Obsessive-Compulsive Disorder (OCD), with disturbances in serotonin neurotransmission contributing to the development and maintenance of symptoms. As with any mental disorder there are a multitude of treatments that can be beneficial to the patient Treatments of OCD These treatments are typically divided into two main areas Pharmacological Non-pharmacological ■ The main differences between these two treatment options are that the pharmacological treatment model focuses upon medications as the primary source of treatment Treatments of OCD ■ Whereas there are a variety of psychotherapies that the patient can be treated with ■ It should be noted that both methods of treatment have their merits and their place in the treatment journey of an individual suffering from OCD Pharmacological treatments Fluvoxamine maleate Sertraline Fluoxetine Escitalopram Clozapine Paroxetine Clomipramine hydrochloride Fluvoxamine maleate ■ Class – Selective Serotonin Re-uptake Inhibitors (SSRI) ■ Dose – 50mg daily (initially), up to 300mg daily Source BNF 2024 Sertraline ■ Class – Selective Serotonin Re-uptake Inhibitors (SSRI) ■ Dose – 50mg daily, up to 200mg daily Source BNF 2024 Escitalopram ■ Class – Selective Serotonin Reuptake Inhibitors (SSRI) ■ Dose – 5mg daily, up to 10mg daily Source BNF 2024 Paroxetine ■ Class – Selective Serotonin Re-uptake Inhibitors (SSRI) ■ Dose – 20mg daily (initially), up to 60mg daily Source BNF 2024 Fluoxetine ■ Class – Selective Serotonin Re-uptake Inhibitors (SSRI) ■ Dose – 20mg daily (initially), up to 60mg daily Source BNF 2024 Clozapine ■ Class – Antipsychotics (second generation) ■ Dose – 12.5mg daily (initially), up to 300mg daily Source BNF 2024 Clomipramine hydrochloride ■ Class – Tricyclic antidepressant ■ Dose – 25mg daily (initially), up to 250mg daily Source BNF 2024 Pharmacological treatments SSRIs, these medications inhibit the reuptake of serotonin neurotransmitters. Antipsychotic (Clozapine), inhibits several neurotransmitters receptors dopamine type 4, serotonin type 2, norepinephrine, acetylcholine, and histamine receptors Tricyclic antidepressant, this medication inhibits the reuptake of serotonin and norepinephrine neurotransmitters Non-pharmacological treatments Cognitive behavioural therapy Neurosurgical Deep-brain stimulation Non-pharmacological treatments Cognitive behavioural therapy Due to the proven efficacy of SSRI’s and CBT they are often used together in clinical settings (Cottraux, et al., 2005) CBT is the most effective evidenced-based psychotherapy for OCD at present. It can also be argued as the most effective treatment for OCD, including pharmacotherapy 36-40. It can be utilised in group, individual, and online settings Non-pharmacological treatments A cognitive reappraisal or restructuring component and behavioural interventions CBT has two components These can be used jointly or independently Exposure-response prevention is a highly utilised form of CBT for OCD. Exposure-response prevention is a structured psychotherapy that exposes the patient to provoking stimuli (Hirschtritt, et al., 2017). Neurosurgical In cases where CBT and SSRI treatment has been unsuccessful in significantly reducing OCD symptoms neurosurgical options are sometimes utilised These include anterior cingulotomy, ventral capsulotomy, subcaudate tractotomy, and limbic leucotomy (Nuttin, et al., 2014) Nonpharmacologic al treatments Non-pharmacological treatments Anterior cingulotomy, creates small lesions on the anterior cingulate gyrus (Kim, et al., 2003) Ventral capsulotomy, creates lesions on the anterior limb of the internal capsule/ventral striatum (Barrios-Anderson, et al., 2022) Subcaudate tractotomy, creates lesions in the substantia innominata (Doshi, 2009) Limbic leucotomy, is a combination of ventral capsulotomy and subcaudate tractotomy (Mashour, et al., 2005) Non-pharmacological treatments ■ Deep-brain stimulation ■ This therapy is another neurosurgical procedure but involves implanting electrodes in specific brain regions to stimulate these regions. ■ In relation to OCD the brain region typically targeted is the anterior limb of the internal nucleus accumbens or the thalamus/subthalamic nucleus (Alonso, et al., 2015) Approaches to SelfManaging OCD ■ Taking medication regularly as prescribed ■ Self-regulating the symptoms ■ Engaging in peer support groups ■ Self-help resources How Does medication Allow People SelfManage OCD and Support Their Mental Wellbeing ■ About 7 out of 10 people with OCD will benefit from medication. For the people who benefit from medication, they usually see their OCD symptoms reduced by 40-60%. For medications to work, they must be taken regularly and as directed by their doctor (Sabetnejad et al., 2016) ■ Some people with OCD that regularly take SSRIs to manage their symptoms can feel less tense and anxious resulting in a positive effect on their lives. Others may not experience symptom relief from taking their medication however despite it not improving symptoms it can prevent them from becoming more severe ■ Medication can also play a crucial role in allowing people that suffer from OCD to have a professional career as if OCD is left untreated severe symptoms can affect work, study and social relationships (Soomro et al., 2008) The Benefits of Self Regulating the Symptoms of OCD ■ Learning and becoming knowledgeable about anxiety has been found to reduce levels of anxiety in people with OCD however, if the information is negative or confusing it can cause increased levels of anxiety ■ Becoming aware of the symptoms of OCD can allow for some people to self-regulate as some people may experience lower levels of stress and anxiety when symptoms occur if they know why they are experiencing these feelings ■ Designing a strategy that will help deal with obsessions will allow people to have a higher probability of self-managing their OCD and increasing their overall mental wellbeing ■ Strategies for OCD typically aim to reduce stress through engaging in a healthy lifestyle. This can include eating a healthy diet, getting enough exercise and improving sleep (Adams et al., 2018) (Charpentier et al., 2022) How Does Engaging in Peer Support Groups Help People Manage the Symptoms of OCD? ■ Peer support groups can improve the mental wellbeing of people suffering from OCD as meeting others with the same experiences can make people feel less lonely and isolated as well as understood ■ Common struggles that people that suffer from OCD have can become normalised making people feel included and providing reassurance that they are not suffering on their own. If a support group is run effectively, it can provide those involved with a sense of community ■ A peer support group can be a non-judgemental which can make it easier for people to open up about their struggles living with OCD ■ Success stories from others can help inspire and motivate people with severe symptoms of OCD and can provide reassurance ■ It has been found that most people do not find success in managing their OCD on their own and peer support groups have been shown to allow people to manage their symptoms better than self-help resources How Does Self Help Resources Have a Positive Effect on the Mental Wellbeing of People Suffering From OCD? ■ Some healthcare professionals such as general practitioners can recommend self-help books to their patients that they can get for free from local libraries ■ Knowledge really is power when it comes to tackling OCD and selfhelp books can provide people with education on OCD which increases their chances of improving their mental wellbeing ■ These resources can also allow people with OCD to build and develop coping strategies when symptoms such as anxiety are present ■ Even if self-help resources do not improve the mental wellbeing of people suffering from OCD, they can definitely provide the foundation and knowledge before trying other approaches ■ Self-help resources can never replace or be as powerful as seeking help through a health care professional however, having general knowledge of OCD before going to therapy can speed up the recovery process THE ROLE OF THE NURSE ➢Mental health nurses have an important role whilst supporting an individual with Obsessive Compulsive Disorder (OCD), by providing psychoeducation, psychotherapy and medications, whilst adapting a holistic approach. ➢By doing so, nurses can tailor each individual patients treatment plan, ensuring all factors such as; spiritual and cultural aspects are considered. ➢This creates the best person-centred care plan for each patient with OCD. ➢By implementing the biopsychosocial model to their practice, nurses can reduce morbidity and mortality, as well as improving the patients cognitive functioning (Gellatly & Molloy, 2014). (Agorastos et al., 2014) THE ROLE OF THE NURSE Assessment ■ A clinical assessment should be carried out by the nurse that includes • History of present illness • Symptoms • Past psychiatric history & family psychiatric history • Social and developmental history • Medical and substance history • Mental status examination. ■ Followed by a risk assessment of self-harm and harm to others. (Pampaloni et al., 2022) THE ROLE OF THE NURSE Supporting Children and Adolescents ■ Previously considered to be rare among children and adolescents, OCD is a more common psychiatric issue within this population, with prevalence rates ranging from 1%-4%. ■ Early detection of OCD is of paramount importance to access effective treatment for children and adolescents. ■ OCD, when left untreated typically persists and it can have a profound negative impact on a young person’s social, educational, and emotional development (Krebs & Heyman, 2013) ■ When the nurse is assessing a child or adolescent with suspected OCD, it is recommended that they meet with both the child/teen and the caregiver. As they can minimize the impact of OCD on their lives due to guilt or shame. ■ OCD symptoms can be hidden from family members, particularly those related to ‘bad thoughts. ■ Younger children tend to have their parents in the room to help with providing a history, while adolescents usually prefer to be seen alone. ■ Therefore, it is important for the nurse to also obtain a separate parent history to provide multiple perspectives (Ramos-Marcuse & Kverno, 2023). THE ROLE OF THE NURSE Supporting Adults ■ The nurse will help patients identify the onset of their OCD symptoms understand the connection between their thoughts, feelings, and ritualistic behaviours, and help them understand how stress and anxiety play into their obsessions ■ Educate patients on the meaning and purpose of their compulsions (such as rituals or routines) (Rapp et al., 2016) ■ Never attempt to interrupt a ritual as this can lead to a rise in anxiety. Instead, patients will be helped to reduce these behaviours, such as repetitive hand washing/checking. ■ This can be done by setting a time limit for routines, slowing decreasing allocated time. ■ Teaching patients how to effectively cope with stressful situations without resorting to obsessive thoughts and /or compulsive behaviours ■ Providing a safe supportive environment. ■ Encouraging compliance with THE ROLE OF THE NURSE Supporting the family ■ The nurse will ;develop a trusting professional relationship with the patient and the family. ■ Listen to the families concerns, whilst educating them on how to best support their loved one. ■ Inform the family on how to recognise when the loved ones mental state would decline. ■ Providing emotional support and reassurance. ■ Educate family in regards to patients medication if being administered (Belschner et al., 2020) References; ■ Agorastos, A., Huber, C.G. and Demiralay, C. (2014) ‘Influence of religious aspects and personal beliefs on psychological behavior: Focus on Anxiety Disorders’, Psychology Research and Behavior Management, p. 93. doi:10.2147/prbm.s43666. ■ Belschner, L. et al. (2020) ‘Mindfulness-based Skills Training Group for parents of obsessive-compulsive disorder-affected children: A caregiver-focused intervention’, Complementary Therapies in Clinical Practice, 39, p. 101098. doi:10.1016/j.ctcp.2020.101098. ■ Gellatly, J. and Molloy, C. (2014) ‘Psychological interventions in obsessive compulsive disorder’, Nursing Standard, 28(51), pp. 51–59. doi:10.7748/ns.28.51.51.e8909. ■ Krebs, G. and Heyman, I. (2013) ‘Treatment‐resistant obsessive‐compulsive disorder in young people: Assessment and treatment strategies’, Child and Adolescent Mental Health, 15(1), pp. 2–11. doi:10.1111/j.1475-3588.2009.00548.x. ■ Pampaloni, I. et al. 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