Bulimia nervosa is a serious mental health disorder characterized by recurrent episodes of binge eating followed by compensatory behaviors, such as self-induced vomiting, excessive exercise, or misuse of laxatives. It affects individuals of all ages, with onset typically occurring during adolescence or young adulthood. Understanding the complexities of bulimia nervosa is crucial for early detection, intervention, and improved outcomes for affected individuals. Epidemiology and Classification Bulimia nervosa is one of the most common eating disorders, with a lifetime prevalence estimated to be around 1-2% in the general population. It is classified under the category of eating disorders in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), which distinguishes between two subtypes: purging and non-purging bulimia nervosa. Etiology and Risk Factors The etiology of bulimia nervosa is multifactorial, involving genetic, biological, psychological, and environmental factors. Genetic studies have identified several genes associated with eating disorders, highlighting the hereditary component of bulimia nervosa. Psychological factors, such as body image dissatisfaction, low self-esteem, and perfectionism, also play a significant role in its development. Environmental factors, including societal pressures, dieting culture, and trauma, contribute to the onset and maintenance of the disorder. Pathophysiology The pathophysiology of bulimia nervosa involves dysregulation of appetite and satiety mechanisms, as well as alterations in brain neurotransmitter systems, such as serotonin and dopamine. Binge eating episodes are driven by intense cravings for high-calorie foods, followed by feelings of guilt, shame, and loss of control. Compensatory behaviors are employed to alleviate distress and mitigate weight gain. Clinical Presentation and Diagnosis Clinical presentation of bulimia nervosa includes recurrent episodes of binge eating, typically accompanied by a sense of lack of control and distress. Compensatory behaviors, such as selfinduced vomiting, excessive exercise, or laxative misuse, are used to counteract the caloric intake from binge eating. Diagnosis is based on criteria outlined in the DSM-5, which include the frequency and severity of binge eating and compensatory behaviors, as well as associated psychological and physical symptoms. Treatment Modalities Treatment of bulimia nervosa involves a multidisciplinary approach, including nutritional counseling, psychotherapy, medication management, and support groups. Cognitive-behavioral therapy (CBT) has been shown to be effective in addressing maladaptive thoughts and behaviors associated with bulimia nervosa. Antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs), may also be prescribed to manage comorbid depression and anxiety. Complications and Prognosis Complications of bulimia nervosa include electrolyte imbalances, dehydration, gastrointestinal problems, dental erosion, and cardiovascular complications. Chronic purging behaviors can lead to serious medical complications, including electrolyte disturbances and cardiac arrhythmias. Prognosis varies depending on the severity of the disorder, early intervention, and adherence to treatment recommendations. Conclusion Bulimia nervosa is a complex eating disorder with significant medical and psychological consequences. Early detection, intervention, and ongoing support are essential for successful recovery and long-term management of the disorder. Continued research efforts are needed to further elucidate its underlying mechanisms and develop more effective treatment strategies.