Diocesan Schools of Urdaneta SAINT ANTHONY ABBOT ACADEMY Villasis, Pangasinan General Biology 2 Modular Activity #1 Pedigree Analysis Lesson 2.4: Pedigree Analysis A pedigree shows the presence or absence of a trait according to the relationships between parents, siblings, and offspring. It can be used for any species, not just humans. The information gained from pedigree analysis makes it possible to determine the nature of genes and alleles associated with inherited human traits. You can determine if an allele for a trait is dominant or recessive, autosomal or sex-linked. Sex-linked traits are traits that are linked with sex chromosomes. It can be X-linked or Y-linked traits. An X-linked trait can NEVER be passed from father to son on the other hand, Y-linked traits will NEVER affect females. The following are the mode of inheritance: 1. X-Linked Recessive Traits Both males and females can be affected, but the trait is much more common in males. Affected males transmit the allele to ALL of their daughters and NONE of their sons Daughters of affected males are always carriers (not affected) unless mother also has the allele Affected female will have affected sons. 2. X-Linked Dominant Traits If the trait is dominant, it will be expected to occur more often in females. ALL daughters of an affected male will be affected (NO carriers) It cannot be passed on from father to son. 3. Y-Linked Traits No affected females ALL sons of affected males are also affected. Diocesan Schools of Urdaneta SAINT ANTHONY ABBOT ACADEMY Villasis, Pangasinan Pedigree Analysis Activity #1 Name:____________________________ Date:___________________ Grade level & Section:______________ Directions: Read the paragraph and answer the questions. Write your answer on a separate paper (1 whole pad paper). Situation: Hemophilia is an example of a sex-linked disorder. Two genes carried on the X chromosome help control blood clotting. A recessive allele in either of these two genes may produce hemophilia. The pedigree shows the transmission of hemophilia through three generations of a family. 1. Whose mothers are definite carriers of the gene? 2. Why did the sons of Person 3 not able to inherit the trait? 3. How could Person 12 have hemophilia if both parents are not affected? Diocesan Schools of Urdaneta SAINT ANTHONY ABBOT ACADEMY Villasis, Pangasinan Performance Activity #2 Pedigree Analysis Pedigree Diagram analysis of your family from first to second generation. (Individual performance task) Make your own pedigree analysis starting from both your parents and to their offsprings (including you). Observe what common trait your family share the most then plot it in your own pedigree analysis Example of traits (for reference): Colorblind mother or sibling, attached earlobe or free earlobe among you. Important instructions to follow Print your own Pedigree Analysis on a LONG COUPON BOND PAPER Landscape Page Orientation Font: Times new roman Font Size: any size but make sure it is neatly placed inside a diagram. Place your full name on the left side then grade level & section below it. Deadline: March 15, 2024 The following below are the activities you need to pass on or before March 15, 2024: 1. Activity 1: Checklist of your family Traits 2. Modular Activity 1: Pedigree Analysis (hemophilia) 3. PETA #2 PEDIGREE ANALYSIS OF YOUR FAMILY Pedigree Analysis Rubric Criteria Pedigree Analysis’ content 0-10 POINTS The student failed to complete two generations of his/her family’s pedigree. Criteria Accuracy on choosing appropriate pedigree diagrams 0-10 POINTS The student failed to properly choose a pedigree diagram on his/her pedigree analysis. Criteria Creativity and Neatness 0-3 POINTS The student did not place any creativity design and the pedigree diagram is not properly aligned. Overall points: 50 POINTS Prepared by: Jennifer C. Orogo 11-15 POINTS The student was able to trace some traits of his/her family’s pedigree but only one generation. 11-15 POINTS The student was able to choose a pedigree diagram but only few on his/her family members. 4-7 POINTS The student was able to design his/her pedigree diagram and neatly aligned. 16-20 POINTS The student was able to excellently trace traits from first to second pedigree generation 16-20 POINTS The student was able to excellently choose appropriate pedigree diagrams from first to second generation. 8-10 POINTS The student displayed high creativity design to his/her pedigree diagram and it is properly aligned.