DRUG STUDY
Source:
Name of Drug
Classification
Mechanism of Action
Indication
Contraindication
Mefenamic acid
Mefenamic acid is Mefenamic acid should
primarily works by
prescribed to relieve not be used under
Mefenamic Acid NSAIDs
inhibiting the enzymes pain and
certain circumstances,
cyclooxygenase-l (COX- inflammation in
such as:
I) and cyclooxygenase-2 various conditions, -hypersensitivity
(COX-2). These
including:
-active peptic ulcers
enzymes are responsible - menstrual cramps
for the production of
- pain and
Trade Name:
prostaglandins, which inflammation
Ponstel
play a role in
inflammation, pain, and
Functional
fever. By inhibiting
Classification
COX-1 and COX-2 COX-I and COX-2,
mefenamic acid reduces
the production of
prostaglandins, leading
to decreased pain,
inflammation, and fever.
Generic Name:
General
Classification
Patient’s Dose:
Patient’s Indication:
-treat for mild to
moderate pain
Maximum Dose:
Minimum Dose:
Adverse Reactions
Nursing Responsibilities
CNS: headache, dizziness,
Before
insomnia
-Check doctor's order
DERMATOLOGIC: rash,
-Assess pain score
pruritus, sweating
Gl: nausea, Gl pain, diarrhea -Assess for history of allergic to NSAID
-Educate patients regarding desired adverse
constipation
GU: dysuria, renal, impairment effect
HEMATOLOGIC: bleeding, -Educate patient that prolonged use of drug
platelet inhibition with higher can damage the liver
dose neutropenia
RESPIRATORY: dyspnea,
During
hemoptysis, pharyngitis
-Do not increase or double the dose follow
the exactly the prescribe and indicated
-Administer the drugs with full glass of
water
-Do not break, chew or crush capsule or
tablet
-Do not administer with anticoagulants and
other drug that causes GI upset
After
-Document accordingly Monitor for adverse
effects
-Instruct discontinuation of medication if
adverse effect occurs
-Assess for occurrence of GI ulcers after
taking