84 % 66 % 77 % Publication bias assesses its influence, describing the methods that have been most recently advanced. Other major topics of discussion in this chapter were sub-group and moderator analysis, including metaregression, to explore variations in ESs due to methodological features and PICO (populations, interventions, comparisons, and outcomes) variables in the primary studies. Sensitivity analysis has been used to discover the extent to which results of meta-analysis are robust for outliers and for decisions and assumptions made during the analysis. Finally, statistical power analysis is an important tool for planning and evaluating meta-analyses 1.How does bias in meta-analysis affect the reliability of the overall results? 2.How can readers determine the quality and credibility of a metaanalysis? 1. 2. 3. How can students evaluate the quality of meta-analyses and Systematic Reviews by considering bias and variation? Why is it important to critically assess the of bias and variation in research synthesis? How can critical thinking skills help students become discerning consumers of meta-analyses and Systematic Reviews? 1)Assignment Overview: Students will conduct a research on a meta-analysis or Systematic Review related to their field of interest. They should critically evaluate the quality of the research synthesis by considering bias and variation. The teacher should provide guidance on the evaluation criteria. 2)Assignment Question: Choose a meta-analysis or Systematic Review article and identify potential sources of bias and variation. Explain how these biases and variations can affect the reliability of the overall results. Provide recommendations on how to minimize bias and variation in future research synthesis.