Homeostasis The conditions inside our body must be very carefully controlled if the body is to function effectively. Homeostasis is the maintenance of a constant internal environment. The nervous system and hormones are responsible for this. One example of homeostasis is the concentration of carbon dioxide in the blood being carefully controlled. Here are some of the other internal conditions that are regulated: Body temperature This is controlled to maintain the temperature at which the body’s enzymes work best, which is usually 37°C. Blood sugar level This is controlled to provide cells with a constant supply of glucose for respiration. It is controlled by the release and storage of glucose, which is in turn controlled by insulin. Water content This is controlled to protect cells by stopping too much water from entering or leaving them. Water content is controlled by water loss from: the lungs - when we exhale the skin - by sweating the body - in urine produced by the kidneys Negative feedback Homeostatic control is achieved using negative feedback mechanisms: if the level of something rises, control systems reduce it again if the level of something falls, control systems raise it again Negative feedback flowchart Regulating body temperature The human body is designed to function most efficiently at 37ºC. If you become too hot or too cold, there are ways in which your body temperature can be controlled. Too hot When we get too hot: Sweat glands in the skin release more sweat. The sweat evaporates, removing heat energy from the skin. Blood vessels leading to the skin capillaries become wider - they dilate - allowing more blood to flow through the skin, and more heat to be lost. Too cold When we get too cold: Muscles contract rapidly - we shiver. These contractions need energy from respiration, and some of this is released as heat. Blood vessels leading to the skin capillaries become narrower - they constrict - letting less blood flow through the skin and conserving heat in the body. The skin The hairs on the skin also help to control body temperature. They lie flat when we are warm, and rise when we are cold. The hairs trap a layer of air above the skin, which helps to insulate the skin against heat loss. The hypothalamus is the part of the brain which monitors the body's temperature. It receives information from temperature-sensitive receptors in the skin and circulatory system. The hypothalamus responds to this information by sending nerve impulses to effectors to maintain body temperature. For example, if we become too cold, the hair erector muscles contract. This raises the skin hairs and traps a layer of air next to the skin. Skin hairs lie flat when we are hot and stand upright when we are cold Negative feedback mechanisms control body temperature. They include the amount of: shivering (rapid muscle contractions release heat) sweating (evaporation of water in sweat causes cooling) blood flowing in the skin capillaries Negative feedback in temperature regulation Vasoconstriction and vasodilation These diagrams show the processes that take place when vasoconstriction and vasodilation occur. The amount of blood flowing through the skin capillaries is altered by vasoconstriction and vasodilation Regulating blood glucose Glucose is needed by cells for respiration. It is important that the concentration of glucose in the blood is maintained at a constant level. Insulin is a hormone - produced by the pancreas - that regulates glucose levels in the blood.