1 BREATHING This is the inhalation (taking in) and exhalation (giving out) of air. The proportions of gases in inhaled and exhaled air are different as shown by the table below. Gas Nitrogen Oxygen Noble gases Carbon dioxide Water vapour Inhaled air (%) 78 21 1 0.03 0/ variable Exhaled air (%) 78 16 1 4 1/saturated The body of a mammal is differentiated into two parts, an upper thorax and a lower abdomen. The thorax and abdomen are separated by a dome-shaped muscular wall known as the diaphragm. The thorax is supported by a bony frame-work and consists of the thoracic cavity. It is made up of the breast bone (sterum) infront, the backbone (vertebral column) at the back and twelve pairs of ribs at the sides. The ribs are attached to the back bone and the breast bone, hence forming a bony cage. They are connected to one another by muscles known as the intercostal muscles. The respiraroty system The inside of the thoracic cavity is lined with a thin membrane known as the outer pleural membrane. This membrane folds over so that part of it covers the lungs. This part is known as the inner pleural membrane. The space between the two membranes is known as the pleural cavity and is filled with a fluid which allows the lungs to move smoothly and prevent them from sticking to the chest wall. Oxygen is used by the body cells and carbon dioxide is produced. Oxygen and carbon dioxide are exchanged between the inhaled air and the blood across the inner surface of the lungs in structures called alveoli (air sacs). Beyond the pharynx, in the region of the throat lies the larynx (voice box). This structure leads into a long tube called the trachea (windpipe). At its base, it branches into two bronchi. Each one enters a lung and in turn branches into several bronchioles. These bronchioles and their smaller branches terminate into groups of tiny air sacs called alveoli. There are two lungs (left and right). Each lung is a soft, pink, spongy structure. It consists of many lobes, each lobe is made up of several millions of alveoli. 2 The membrane which lines the upper respiratory tract (trachea, bronchus and bronchiole) is well supplied with blood, which warms the air to body temperature. Hairs in the nasal passage filter out large particles of dust. A sheet of mucus lines the respiratory tract and traps bacteria, viruses and dust particles. The mucus comes from cells in the membrane lining called goblet cells. Cilia, rows of fine hairs, sway to and fro and sweep the mucus with the trapped substances into the pharynx, where it is either swallowed, sneezed out or coughed up. The air which then passes to the lungs is cleaned and freed from germs. Roles of the ribs, intercostals muscles and diaphragm in breathing 1. Inhalation (breathing in) a. b. c. d. e. f. g. h. External intercostals muscles contract Internal intercostals muscles relax Ribcage moves upwards and outwards Diaphragm muscles contract Diaphragm flattens Volume of thoracic cavity increases (lungs expand) Pressure in the lungs decreases Air rushes into the lungs ` 3 2. Exhalation (breathing out) a. b. c. d. e. f. g. h. External intercostals muscles relax Internal intercostals muscles contract Ribcage moves downwards and inwards Diaphragm muscles relax Diaphragm assumes a dome-shape Volume of thoracic cavity decreases (lung volume decreases) Pressure in the lungs increase Air is forced out of the lungs Exchange of gases at the alveoli In inhaled air, there is higher concentration of oxygen in the alveoli than in the blood. This allows oxygen to diffuse from the alveolus into the blood. There is more carbon dioxide in the blood coming towards the alveolus than in the inhaled air in the alveolus, therefore carbon dioxide diffuses from the blood into the alveolus. 4 Features of the alveoli which allow gaseous exchange. 1. An alveolus is one cell thick which allows gases diffuse across its walls 2. It has film of moisture which dissolves gases to allow rapid diffusion from the alveolus into the blood 3. Close to a network of blood capillaries which allows gases to travel shorter distances between it and the blood 4. Numerous in number which increases surface area for exchange of gases. Effects of tobacco smoke and its major components on health Major components of tobacco smoke i.tar ii. nicotine iii. carbon monoxide EFFECTS OF TOBACCO SMOKE 1. Lung cancer Tar contains chemical substances called carcinogens which trigger the abnormal multiplication of cells in the lungs leading to cancer of the lungs. 2. Bronchitis Some chemicals in tar lead to overproduction of mucus and also stop cilia from beating/moving. This result in the mucus and trapped substances eg. Bacteria being clogged in the air passages, leading to infection. Infection result in the inflammation of the air passages and difficulty in breathing leading to a condition called bronchitis. 3. Emphysema Some chemicals in tobacco smoke weaken the alveoli and as a smoker coughs due to irritant substances in tobacco smoke, the weakened alveoli break. This reduces the surface area for gaseous exchange which may result in a person experiencing breathing problems. This condition is called emphysema. The person may become breathless and exhausted. 5 4. Heart problem The carbon monoxide increases the rate at which fatty material is deposited in the arteries. The nicotine and carbon monoxide from tobacco smoke promote formation of blot clots in the blood vessels which may lead to heart attack. Effect on pregnant woman Carbon monoxide in tobacco smoke diffuses into the blood preventing supply of oxygen to the foetus . This may result in miscarriages, still births or babies born underweight.