CHAPTER I: INTRODUCTION TO THE HUMAN BODY ____________________ ____ ANATOMY - From the greek word ANA = “up, above or top” and TOME = cutting - Study of body structures of organism and their parts detailed images of organs and tissues. (Diagnose a variety of conditions, from torn ligaments to tumors) (Computed Tomography) CT Scan – combines a series of x-ray images in different angles and creates cross-sectional images (slices) of the bones, blood vessels and soft tissue.(e.g. complex bone fractures, internal injuries and bleeding) X-ray – a photographic or digital image of the internal composition. Mainly used to look at the bones and joints but sometimes used to detect problems affecting soft tissue, such as internal organs. (e.g. bone fractures and breaks) ________________________ AREAS Human Anatomy – study of the structures in the human body. Zootomy (Zoology) – animals PHYSIOLOGY - Ancient greek; PHYSIS - nature or origin and LOGIA – study - Study of the functions of different body parts Phytotomy – plants WAYS Gross or Macroscopic – large; can be seen with the naked eye Microscopic – uses microscope Histology – microscopic structure of tissues Dissection – cutting up; cutting open Endoscopy - tube will be inserted with a camera Angiography – x-ray imaging to examine blood vessels; uses dye injection (soft tissue: black, bones: white) MRI (Magnetic Resonance Imaging) – medical imaging technique that uses a magnetic field and computer-generated radio waves that create PERSONALITIES AND HISTORY Hippocrates (420 BC) - “Father of Medicine” - Theory of four humors - Bile, phlegm, blood, yellow bile - Any imbalance in their ratios will cause ill health Claudius Galenus (Galen) - Modified Hippocrates’ theory - Founder of experimental physiology - First to use experimentation Jean Fernel - Coined the term “physiology” - Described spinal canal - Fernelius - moon crater William Harvey - systemic circulation Matthias Schleiden and Theodor Schwann - body was made up of tiny cells - Schleiden: plants; use of cork - Schwann: animals 3. Evolutionary Physiology - parts of system, have adapted and change over multiple generations 4. Defense Physiology - changes to potential threat 5. Exercise Physiology - physiology of physical exercise ANATOMICAL POSITION - subject stand erect facing forward, upper limbs at the side with palms facing forward and the lower limbs are parallel with the feet flat on the floor. BASIC REFERENCE SYSTEMS Body Planes - imaginary flat surfaces that pass through body parts and divide into sections Joseph Lister - coagulation and antiseptics Ivan Pavlov - conditioned physiological responses in dogs August Krogh - blood flow in capilliaries Andrew Huxley and Alan Hodgkin - mechanism by which nerve impulses are transmitted Andrew Huxley and Hugh Haxley - sliding filaments in skeletal muscle ________________________ DISCIPLINES OF PHYSIOLOGY 1. Cell Physiology - way cells work and interact 2. Systems Physiology - describes individual converge to respond as whole · Frontal (Coronal) Plane - divides body into front (anterior) and back (posterior) parts. · Midsagittal Plane - vertical plane that passes through the midline; divides the body into equal left and right parts. · Parasagittal Plane - divides the body into unequal left and right sides. · Transverse Plane (Horizontal Plane) divides the body into upper (superior) and lower (inferior) portions. Medial Closer to midline Lateral farther/away from the midline of the body · Oblique Plane - passes through the body at an oblique angle. Superficial Closer to the surface of the body Supine Position - lying horizontally with the face and torso facing up Deep Structures farther away from the surface of the body Prone Position - as opposed to the prone, which is face down Cranial Towards the head ______________________ Caudal Towards the tail Directional Terms - describes the position of one body part relative to another. ________________________ Body Cavities - spaces that enclose internal organs Anterior/Ventral Front Posterior/ Dorsal Back Superior Above Inferior Below Proximal Closer to the point of origin Distal farther/away from point of origin A. Dorsal Cavity Cranial Cavity - contains brain Vertebral Canal (Spinal Cavity) - formed by vertebral column and contains spinal cord B. Ventral Cavity 1. Thoracic Cavity - chest cavity Pericardial Cavity - surrounds the heart Pleural Cavity - surrounds the lungs Mediastinum - central portion of the thoracic cavity; partition containing the heart, thymus, trachea and esophagus 2. Abdominopelvic Cavity Abdominopelvic Regions - divides the abdominopelvic cavity into nine regions Quadrants - divides the abdominopelvic cavity into 4 quadrants Abdominal Cavity - contains stomach, spleen, liver, gallbladder, small intestine and most of the large intestine. Pelvic Cavity - contains urinary bladder, portions of large intestine and the reproductive system. Viscera - tissue that covers, lines, partitions or connect structures. · Serous Membrane - double layer membrane that lines internal body cavities and organs such as the heart, lungs and abdominal cavity. Parts of a Serous Membrane: A. Parietal Layer - thin epithelium that lines the walls of the cavities B. Visceral Layer - covers and lines the outer surface of organs · · · Pleura - surrounds the lungs Pericardium - serous membrane of the pericardial cavity Peritoneum - serous membrane of the abdominal cavity _______________________ ________________________ LEVELS OF STRUCTURAL ORGANIZATION 1. Chemical level - includes atoms and molecules; how atoms interact to combine into molecules. 6. Reproduction - formation of new cells/organism HOMEOSTASIS - maintains balance 2. Cellular level - molecules combine to form cells, basic structural and functional units of life. 3. Tissue level - group of cells that work together to perform specific functions -Maintenance of the body’s internal environment Body fluids Intracellular Fluid /ICF- inside the cell 4. Organ level - composed of two or more tissue types Extracellular Fluid /ECF- outside the cell 5. Organ System level - system that consists of related organs with common functions -plasma, lymph, CSF, synovial. Aqueous and vitreous humor 6. Organismal level - any living individual; all parts of the human body functioning together constitute the total organism Interstitial fluid- between the cell ________________________ Characteristics of Life (MRMGDR) 1. Metabolism - ability to use energy to function · Catabolism - breaking down of complex chemical substances to simpler components. · Anabolism - building up of complex chemical substances from smaller components. 2. Responsiveness - ability to sense and respond to changes in the environment. 3. Movement - motion of the whole body, organs, and cells. 4. Growth - increase in size 5. Differentiation - developmental changes from an unspecialized to specialized state. -body’s internal environment Feedback Mechanism Negative feedback- if the body is in normal state already, it will stop Positive feedback- mostly seen during delivery and it reinforce controlled condition