NUMW1220 Midwifery Therapeutics Aisling Vaughan – Midwifery Lecturer Winter 2024 Class 1 Introduction 3 Agenda Course Outline 10 Assessments 11 Homeostasis 14 Summary 32 Meet your Educators AISLING VAUGHAN ERIN DEAN Midwifery Lecturer Clinical Instructor Office: 20.2.71 Office: 20.2.74C Office hours: Tuesday 10.30am to 12.00pm and Wednesday 10.30am to 12.00pm Office hours: Tuesday 12:30pm – 2pm / Wednesday 1:30pm – 3pm aisling.vaughan@udst.edu.qa Erin.dean@udst.edu.qa Email request for appointments are encouraged – please use your UDST account! Winter 2024 NUMW 1220 Introduction & Homeostasis 3 Hello! Education • BSc in General Nursing (with Honours) - University College Cork, Ireland (2012) • PG-Dip in Midwifery (with Honours) - City University London, England (2015) • MSc in Midwifery (Distinction) - City University London, England (2018) • MBA (Distinction) - University of London (2022) Work Experience • Staff Nurse, Cork University Hospital, Cork, Ireland - Sep 2012-Mar 2013 • Staff Nurse, Whipps Cross University Hospital, London, UK - Feb 2013- Sep 2013 • Midwife (Band 6), Homerton University Hospital, London, UK - May 2015-Feb 2018 • Clinical Midwife (Obstetric Triage), Sidra Medicine, Doha, Qatar - Apr 2018-Aug 2023 Winter2024 NUMW 1220 Introduction & Homeostasis 4 Fun fact about me I gave birth to twins in October 2022 at Al Wakra Hospital – a boy and a girl. Classroom Guidelines MISSED LECTURE If you miss a lecture, you can only attend that week's lab if you make up the assigned activities prior to the lab. PHONES Should be on silent and can only be used for classroom activities. ***PUNCTUALITY*** Be on time! If you are more than 10 minutes late, you may be denied entry to the class and/or marked as absent for the class. ABSENCE RESPECT Kindly offer respect to all peers and instructors. Please email me/your clinical instructor as early as possible if you will be absent for a class. Missed Assessments o If a student misses an exam, they must follow school policy to ensure student services amends their attendance record to mark them as excused. Winter2024 o The student may redo the assessment in the same or different format as the original assessment. o The instructor may choose to grade the student assessment based on the grade received on the final exam assessment. NUMW1220 Introduction & Homeostasis o Instructors reserve the right to conduct interviews (additional verbal assessments) with any student to clarify the details or authenticity of submitted student's work. 7 Attendance ➢ If you miss more than 15%, you are at risk for an attendance FAILURE. ➢ If you are late for class, this will count towards absenteeism. ➢ More than 24hrs sick leave should be sent to the attendance office and copy me. ➢ If you are more than 10 minutes late, you will be prevented from participating in the class and will be marked as absent. If you are late when there is planned group learning, you may not be permitted to enter after the class has started as this may interrupt the learning. Winter 2024 NUMW 1220 Introduction & Homeostasis 8 MIDWIFERY THERAPEUTICS Students are introduced to the theoretical bases and application of midwifery therapeutics that underpin midwifery practice. The focus is understanding foundational midwifery biophysical and psychosocial concepts, homeostatic adaptive responses, and the application of women- and person-centred approaches and midwifery therapeutics that balance, support, and sustain the health of mothers and newborns. Winter2024 NUMW 1220 Introduction & Homeostasis 9 Student Syllabus NUMW1220 Student Syllabus.docx ▪ Available on D2L ▪ Please read it carefully! ▪ Follow topic planner week by week Assessments Type of Assessment Assessment Weight D2L Quiz (2 quizzes x 5% each) 10% Midterm Laboratory Exam 20% Midterm Theory Exam 20% Due Date Week 4: January 29th 2024 at 9.30am Week 11: March 18th 2024 at 9.30am Week 6: Week commencing February 11th 2024 Week 7: Week commencing February 18th 2024 Final Laboratory Exam 20% Week 13: Week commencing March 31st 2024 Final Theory Exam 30% Week 16: Week commencing April 21st 2024 Winter2024 NUMW 1220 Introduction & Homeostasis 11 Texts CORE POTTER, P., PERRY, A. G., STOCKERT, P., HALL, A., ASTLE, B. J., & DUGGLEBY, W. (2019). CANADIAN FUNDAMENTALS OF NURSING (6TH ED.). MOSBY. GIDDENS, J.F. (2021). CONCEPTS FOR NURSING PRACTICE (3RD ED.). ELSEVIER. BOWEN, R. & TAYLOR, W. (2021). SKILLS FOR MIDWIFERY PRACTICE (5TH ED.). ELSEVIER. RECOMMENDED CORE BOWEN, R. & TAYLOR, W. (2021). SKILLS FOR MIDWIFERY PRACTICE (5TH ED.). ELSEVIER. MACDONALD, S., & JOHNSON, G. (2023). MAYES’ MIDWIFERY (16TH ED.). ELSEVIER. Homeostasis Learning Outcomes 1 Define the terms “internal environment” and “homeostasis”. 2 Compare and contrast negative and positive feedback control mechanisms. 3 Outline the potential consequences of homeostatic imbalance. Winter2024 NUMW Introduction & Homeostasis 14 Homeostasis The body’s ability to maintain a stable internal environment in response to various internal and external challenges. Herlihy, B. (2022). The human body in health and illness (7th ed.). Elsevier. Homeostasis: Staying (stasis) the Same (homeo) “The term refers to the body’s ability to maintain a stable internal environment in response to a changing environment.” o For example, in a healthy person, body temperature stays at approximately 37°C, even when room temperature increases to 40°C or decreases to 5°C. o The amount of water in your cells stays the same whether you drink 2, 3, or 4 L of water per day. o Your blood sugar remains within normal limits whether you have just eaten a biryani or have fasted for 6 hours. o Mechanisms that help to maintain homeostasis are called homeostatic mechanisms. o Homeostatic imbalance results in disease or dysfunction. Herlihy, B. (2022). The human body in health and illness (7th ed.). Elsevier. Winter2024 NUMW 1220 Introduction & Homeostasis 16 External vs Internal Environment THE EXTERNAL ENVIRONMENT ❖ The external environment is the collection of physical, chemical and biological conditions external to a living organism. THE INTERNAL ENVIRONMENT ❖ The internal environment is the water-based medium in which body cells exist. ❖ Cells are bathed in fluid called interstitial or tissue ❖ It is the source of oxygen and nutrients required by all cells, but it is constantly fluid, from which they absorb oxygen and nutrients and into which they excrete their wastes. changing and is often hostile to the body. ❖ The composition of the interstitial fluid is largely determined by the circulating blood, which supplies oxygen and nutrients and absorbs and carries away Waugh, A., & Grant, A. (2023). Ross & Wilson Anatomy and Physiology in Health and Illness (14th ed.). Elsevier. Winter2024 wastes. NUMW 1220 Introduction & Homeostasis 17 Homeostasis ❖ The composition of the internal environment is tightly controlled, and this fairly constant state is called homeostasis. ❖ Literally, this term means ‘unchanging’, but in practice it describes a dynamic, ever-changing situation where a multitude of physiological mechanisms and measurements are constantly adjusted to keep them within narrow limits. ❖ When this balance is threatened or lost, there is a serious risk to the well-being of the individual. Waugh, A., & Grant, A. (2023). Ross & Wilson Anatomy and Physiology in Health and Illness (14th ed.). Elsevier. Winter2024 NUMW 1220 Introduction & Homeostasis 18 Homeostasis Box 2.1 lists some important physiological variables maintained within narrow limits by homeostatic control mechanisms: Waugh, A., & Grant, A. (2023). Ross & Wilson Anatomy and Physiology in Health and Illness (14th ed.). Elsevier. Winter2024 NUMW 1220 Introduction & Homeostasis 19 Control Systems * Homeostasis is maintained by control systems that detect and respond to changes in the internal environment. * A control system has three basic components: sensor (detector), control centre and effector. * The control centre determines the limits within which the variable factor should be maintained. * It receives and integrates information from the sensor. * When the incoming information indicates that an adjustment is needed, the control centre responds and changes its output to the effector, which actually makes the change. * This dynamic process allows constant, flexible readjustment of many physiological variables. Winter 2024 NUMW Introduction & Homeostasis 20 Negative Feedback Mechanisms o Negative feedback (Fig. 2.12) means that any movement of a control system away from its normal set point is negated (reversed). o If a variable rises, negative feedback brings it down again, and if it falls, negative feedback brings it back up to its normal level. o The response to a change therefore reverses the change, keeping the system in a steady state and maintaining homeostasis. Winter 2024 NUMW 1220 Introduction & Homeostasis 21 Negative Feedback Mechanisms Body temperature is one example of a physiological variable controlled by negative feedback (Fig. 2.13). A fall in body temperature below the preset level (close to 37°C) is detected by specialised temperature-sensitive nerve endings, mainly in the skin. They relay this information to the body’s temperature control centre, found in the hypothalamus of the brain. The hypothalamus then activates mechanisms that raise body temperature (effectors). Winter 2024 NUMW 1220 Introduction & Homeostasis 22 Homeostasis and Negative/Positive Feedback Homeostasis and Negative/Positive Feedback – YouTube 6.23 minutes Winter 2024 NUMW 1220 Introduction & Homeostasis 23 Activity: High-Low-Haha Instructions: 1. High: Think of a positive experience or something good that happened to you recently. 2. Low: Reflect on a challenging situation or something you found difficult recently. 3. Haha: Recall a funny moment or something that made you laugh recently. Winter2024 NUMW 1220 Introduction & Homeostasis 24 Positive Feedback Mechanisms There are only a few of these cascade or amplifier systems in the body. In positive feedback mechanisms, the stimulus progressively increases the response, so that as long as the stimulus is continued, the response is progressively amplified. Examples include blood clotting and uterine contractions during labour. Winter2024 NUMW 1220 Introduction & Homeostasis 25 Positive Feedback Mechanisms o During childbirth, the posterior pituitary releases increasing amounts of oxytocin into the bloodstream in response to increasing stimulation of sensory stretch receptors in the uterine cervix as the baby’s head progressively dilates it. o Sensory impulses are generated and transmitted to the hypothalamus, stimulating the posterior pituitary to release more oxytocin. In turn, this stimulates more forceful uterine contractions and greater stretching of the uterine cervix as the baby’s head is forced further downwards. o This is an example of a positive feedback mechanism, which stops soon after the baby is delivered and cervical stretching stops (Fig. 9.5). Winter 2024 NUMW 1220 Introduction & Homeostasis 26 Positive Feedback Mechanisms o Ejection of milk also involves a positive feedback mechanism. Suckling generates sensory impulses that are transmitted from the breast to the hypothalamus, triggering release of oxytocin from the posterior pituitary. o On reaching the lactating breast, oxytocin stimulates contraction of the milk ducts and myoepithelial cells around the glandular cells, ejecting milk. o Suckling also inhibits the release of prolactin inhibiting hormone (PIH), prolonging prolactin secretion and lactation. Winter2024 NUMW1220 Introduction & Homeostasis 27 Homeostatic Imbalance o The body’s homeostatic mechanisms are sophisticated and highly efficient, but their capacity to adapt to stress is limited. o If the change in a system is excessive, especially if it happens rapidly, they may not be able to adapt and the system may shift outside the normal physiological range. o This can lead to disruption or disease if it is not corrected. Winter 2024 NUMW1220 Introduction & Homeostasis 28 Quiz Time Let’s see what you remember. Microsoft Forms (office.com) Summary Negative Feedback Mechanisms Positive Feedback Mechanisms Homeostatic Imbalance o Negative feedback works like a thermostat. o If our body temperature gets too cold, mechanisms such as shivering help warm us up. o On the other hand, if we become too hot, our body sweats to help us cool down, bringing us back to a comfortable temperature. o Positive feedback builds on itself until a goal is reached. o During childbirth, for example, contractions become stronger and more frequent until the baby is born. o Similarly, when a baby feeds, the mother produces more milk in response to the baby's suckling. o If our body's natural balance mechanisms are overwhelmed and can't adapt quickly enough, it can lead to illnesses or other health issues. o It's like a seesaw that can't find its balance. Winter2024 NUMW1220 Introduction & Homeostasis 30 Reference List o Herlihy, B. (2022). Chapter 1: Introduction to the human body. In B. Herlihy, The human body in health and illness (7th ed., pp. 6-7). Elsevier. o Waugh, A., & Grant, A. (2023). Chapter 2: Physiological chemistry and processes. In A. Waugh & A. Grant, Ross & Wilson anatomy and physiology in health and illness (14th ed., pp. 36-37). Elsevier. Winter 2024 NUMW1220 Introduction & Homeostasis 31 Thank You Have a great week! Don’t forget to do your reading!