Roseola Infantum ● Caused by human herpes 6 and 7 ● Herpesviridae (dsDNA viruses with enveloped icosahedral capsids) ● Children under 3 ● Spread via respiratory fluids or direct contact ● Presents with high fever that lasts 3-5 days look for respiratory symptoms ● Rash is blanching macular or maculopapular rash that persists for 1-2 days after the infection has subsided ○ Starts at neck and trunk and spreads to extremities and face Warts ● ● ● ● ● Caused by infection with papillomaviruses icosahedral dsDNA non enveloped viruses STI HPV 1 and 4: plantar warts HPV 2, 3, 10 cause warts on knees and fingers Appearance ○ Filiform with finger like projections ○ Flat topped ○ Cauliflower like protuberance ○ Dysplasia on the cervix Measles ● Presents with koplik’s spots seen as white dots on the inflamed buccal mucosa and a maculopapular rash on the face and the trunk Varicella Zoster ● Causes chicken pox ● Highly contagious: nasopharyngeal secretions ● Herpesviridae: dsDNA, icosahedral enveloped capsid ● Begins as macules that rapidly become papules: itchy rash ● Rash appears as successive crops that progress in a specific pattern Shingles ● Herpes virus is forever, VSV is a herpesvirus ● VSV goes latent in sensory nerve ending in the skin ● Rash begins as painful erythematous papules along a single or several contiguous, dermatomes, within several days grouped vesicles develop ● Intensely painful