A COMBINE EVALUATION OF DIFFERENT ANTIBODIES AND THEIR RESISTANCE A project report Submitted in fulfillment of the requirements for the award of the degree Of BACHELOR OF PHARMACY NISHANT YADAV (MAU20BPH059) Under the Supervision of Mr. Pankaj Kalia Assistant Professor (subject) Maharaja Agrasen School of Pharmacy Maharaja Agrasen School of Pharmacy MAHARAJA AGRASEN UNIVERSITY ATAL SHIKSHA KUNJ, KALUJHANDA BAROTIWALA (SOLAN) – 174103 (H.P.), INDIA DECEMBER, 2023 DECLARATION It is certified that the project entitled, “A combine evaluation of different antibodies and their resistance” is a bonafide work carried out by Nishant Yadav at Maharaja Agrasen School of Pharmacy, Maharaja Agrasen University under the supervision of Mr. Pankaj Kalia. The matter embodied in the project has not been submitted for the award of any other degree. I declare that I have faithfully acknowledged and given credits to the research workers wherever their works have been cited in my work in this project work. I further declare that I have not wilfully copied any other’s work, paragraphs, text, data, results etc. reported in journals, books, magazines, dissertation, thesis etc. or available at website and have not included them in this project work and not cited as my own work. Date: Place: Nishant Yadav i Maharaja Agrasen School of Pharmacy MAHARAJA AGRASEN UNIVERSITY BADDI, SOLAN (H.P.) - 174103 CERTIFICATE It is certified that the present work contained in the project titled “A combine evaluation of different antibodies and their resistance” has been carried out by Nishant Yadav under my direct supervision and guidance, the finding of which have been incorporated in this dissertation. He has carried out his studies very sincerely, meticulously and methodically. It gives me immense pleasure and satisfaction in forwarding his thesis for the award of Bachelor of Pharmacy. Supervisor Mr. Pankaj Kalia ii Maharaja Agrasen School of Pharmacy MAHARAJA AGRASEN UNIVERSITY BADDI, SOLAN (H.P.) - 174103 Ref. No. Date: CERTIFICATE It is certified that Nishant Yadav has worked for his project work on the titled “A combine evaluation of different antibodies and their resistance” under the supervision of Mr. Pankaj Kalia. This is an original work and all the help taken during the course of the study has been duly acknowledged. I find it worthy of submission his project work for the award of Bachelor of Pharmacy. Director iii ACKNOWLEDGEMENT I convey my gratitude to my esteemed supervisor, Mr. Pankaj Kalia, Assistant Professor (Pharmacognosy) Maharaja Agrasen School of Pharmacy, Maharaja Agrasen University, Baddi, India. This work could have almost not viable without his consistent guidance, supports and regular encouragement. I gratefully thank Director, HODs, all the supporting teaching and non-teaching staff members, Maharaja Agrasen School of Pharmacy, Maharaja Agrasen University, Baddi, India, for providing healthy research environment to carry out my project work, in this pioneer institution. My sincere thanks go to my dear seniors and friends for their unconditional support and encouragement. And above all, special thanks to my family members for their divine blessings, affection, patience and confidence in me, which helped me to complete the present work successfully. This Project work would not have been possible without guidance and help of several individuals, who, in several possible ways contributed and extended their valuable support for this study. Nishant Yadav iv Contents Sr. No. Topic Page No. 1. Introduction 1-2 2. Review of Literature 3-17 3. Aim and Objective 18 4. Reference 19 v List of Tables Sr. No. 1. Table No. Table-1 Description Classes of antibiotics and their properties vi Page No. 4 List of Figures Sr. No. Figure No. Description 1. 1 Penicillin 3 2. 2 Structure of penicillin 4 3. 3 Sir Alexander Fleming 4 vii Page No.