INDEX I 1. WHAT IS CANCER? 2. COMMON TYPES OF CANCER 3. SIGNS AND SYMPTOMS 4. DIFFERENCE BETWEEN NORMAL CELLS AND CANCER CELLS 5. HOW DOES CANCER CELLS GET ACTIVATE? 6. PREVENTION STEPS 7. DEVELOPMENT OF CANCER 8. MAIN CAUSES OF CANCER 9. TREATMENT OF CANCER 10.CASE STUDY 11.BIBLIOGRAPHY STUDY OF CANCER 1. WHAT IS CANCER? Cancer is a disease in which some of the body’s cells grow uncontrollably and spread to other parts of the body. Cancer can start almost anywhere in the human body, which is made up of trillions of cells. Normally, human cells grow and multiply (through a process called cell division) to form new cells as the body needs them. When cells grow old or become damaged, they die, and new cells take their place. Sometimes this orderly process breaks down, and abnormal or damaged cells grow and multiply when they shouldn’t. These cells may form tumors, which are lumps of tissue. Tumors can be cancerous or not cancerous (benign). Cancerous tumors spread into, or invade, nearby tissues and can travel to distant places in the body to form new tumors (a process called metastasis). Cancerous tumors may also be called malignant tumors. 2.COMMON TYPES OF CANCER • Bladder Cancer • Breast Cancer • Colorectal cancer • Kidney Cancer • Lung Cancer • Melanoma • Oral and Oropharyngeal Cancer • Pancreatic Cancer • Prostate Cancer • Thyroid Cancer • Uterine Cancer • Brain Cancer 3. SIGNS AND SYMPTOMS •Fatigue or extreme tiredness that doesn’t get better with rest. •Weight loss or gain of 10 pounds or more for no known reason •Eating problems such as not feeling hungry, trouble swallowing, belly pain, or nausea and vomiting •Swelling or lumps anywhere in the body •Thickening or lump in the breast or other part of the body •Pain, especially new or with no known reason, that doesn’t go away or gets worse •Skin changes such as a lump that bleeds or turns scaly, a new mole or a change in a mole, a sore that does not heal, or a yellowish color to the skin or eyes (jaundice). •Cough or hoarseness that does not go away •Unusual bleeding or bruising for no known reason •Change in bowel habits, such as constipation or diarrhea, that doesn’t go away or a change in how your stools look •Bladder changes such as pain when passing urine, blood in the urine or needing to pass urine more or less often •Fever or nights sweats •Headaches 4. DIFFERENCE BETWEEN NORMAL CELLS AND CANCER CELLS • Normal cells divide only when they receive a set of appropriate signals whereas cancer cells divide themselves despite the absence of those signals, and they are resistant to the signals telling them to self-destruct, known as apoptosis or programmed cell death. • Cancer cells fuel their growth with different nutrients than normal cells and some utilize different pathway to transform those nutrients into energy, allowing them to proliferate faster than normal cells. For instance, tumor can induce new blood vessels formation (Angiogenesis), bringing in more nutrients supply. • Normal cells stop dividing when touching other cells. They usually do not migrate to other areas. Cancer cells, on the contrary, invade into surrounding tissues and spread to other organs. • Cancer cells can evade our immune system elements which normally eliminate abnormal or invading cells. They can co-opt our immune system to help them proliferate. For instance, cancer cells can disguise as normal cells via antigen expression on the cell membrane. 5. HOW DOES CANCER CELLS GET ACTIVATED A Gene mutations in cancer cells interfere with the normal instructions in a cell and can cause it to grow out of control or not die when it should. A cancer can continue to grow because cancer cells act differently than normal cells. Cancer cells are different from normal cells because they: • divide out of control • are immature and don’t develop into mature cells with specific jobs • avoid the immune system • ignore signals that tell them to stop dividing or to die when they should • don’t stick together very well and can spread to other parts of the body through the blood or lymphatic system • grow into and damage tissues and organs As cancer cells divide, a tumor will develop. 6. PREVENTION STEPS 7. DEVELOPMENT OF CANCER 8. MAIN CAUSES OF CANCER Smoking, drinking more than one drink a day for women and up to two drinks a day for men, excessive exposure to the sun or frequent blistering sunburns, being obese, and having unsafe sex can contribute to cancer. 9. TREATMENT OF CANCER SURGERY CHEMOTHERAPY RADIATION 10. CASE STUDY 1. Personal Details • Name:- Rekha Barethia • Age:- 56 Years • Background:- Homemaker, residing with her husband, son, daughter-inlaw, and one grandchild. 2. Medical and Disease History • Rekha began experiencing extreme fatigue and noticed unusual breast lumps. • Following a medical consultation, tests revealed she had stage II breast cancer. • She had no prior history of significant illness or surgeries. 3. Doctor`s First Consultation • During her initial appointments, the doctor examined her breasts and inquired about her general health. • A biopsy was recommended, confirming the breast cancer diagnosis. • The doctor discussed treatment options which included surgery, medications and radiation therapy. 4. Medications and Treatments • Rekha`s treatment plan involved surgical removal of tumor followed by a sequence of chemotherapies and prescribed medications to prevent cancer recurrence. • Dietary recommendations were provided to support her overall well-being. 5. Present Condition • Rekha has undergone surgery and reports feeling better, although she experiences increased fatigue. • Her doctor has confirmed no cancer recurrence, bringin g relief and happiness. And suggested follow up after every 6 months. Her medications include immuno boosters. • She expresses gratitude for the unwavering support of her family and friends during this challenging period. BIBLIOGRAPHY • • • • • www.google.com www.cancer.net www.quora.com www.healthtap.com NCERT TEXTBOOK BIOLOGY