SIDE EFFECTS Short-term side effects of sedatives include: Sleepiness. Dizziness. Difficulty focusing or thinking. Blurred vision. Impaired depth perception. Slowed reaction times and reflexes. Not feeling pain the way you usually do. CONTRAINDICATION Allergy to barbiturates. Prevent severe hypersensitivity reactions. History of addiction to sedative-hypnotic drugs: barbiturates are more addicting than most other anxiolytics Latent or manifest euphoria. May be exacerbated by drug effects Marked hepatic impairment or nephritis. May alter the metabolism and excretion of drugs Respiratory distress and dysfunction. Exacerbated by CNS depression caused by drugs. Pregnancy. Associated with congenital abnormalities Lactation. Has potential for adverse effects on the infant. Acute or chronic pain. Can cause paradoxical excitement which can mask other symptoms Seizure disorder. Abrupt withdrawal of barbiturates can precipitate status epilepticus Chronic hepatic, cardiac, and respiratory diseases. Can be exacerbated by the depressive effects of these drugs. DRUGS AVAILABLE IN THE MARKET Benzodiazepine (as Anxiolytic-Hypnotics) o alprazolam (Xanax) o chlordiazepoxide (Librium) o clonazepam (Klonopin) o diazepam (Valium) o lorazepam (Ativan) o oxazepam (Serax) o triazolam (Halcion) Barbiturates (as Anxiolytic-Hypnotics) amobarbital (Amytal sodium) butabarbital (Butisol) pentobarbital (Nembutal) phenobarbital (Luminal) Other Anxiolytic-Hypnotic Drugs buspirone diphenhydramine (Benadryl) meprobamate (Miltown) promethazine (Phenergan) zolpidem (Ambien)