Life processes The processes which are required for maintaining the complex, well organised structure of living organisms are called life processes. 1. 2. 3. 4. Nutrition Respiration Transportation Excretion Nutrition The process of utilization of food by living organisms to obtain energy is called nutrition Carbon sources: complex – carbohydrates, sugar Simple – glucose lactose (organic carbon source) Plants consume CO2 (inorganic carbon source) Autotrophs : the organisms that can synthesize their own food Example: green plants, some bacteria Heterotrophs : the organisms that cannot synthesize their own food Example: animals, some fungi Nutrition in plants Plants are also called as producers. Mode of nutrition: autotrophic, heterotrophic Autotrophic nutrition Plants prepare their own food by using raw materials such as water, carbon dioxide and minerals in presence of sunlight. This is called photosynthesis. Photosynthesis takes place in leaves bearing chlorophyll. Since they prepare their own food they are called autotrophs. Auto- self; trophs- nourishment All green plants are autotrophs. Plants absorb water and carbondioxide in the presence of sunlight and release oxygen. Raw materials for photosynthesis CO2: It is obtained from the atmosphere through stomata. H2O: Roots absorb water along with minerals from soil and transport them to leaves. Sunlight: Intensity, duration and quality affects the rate of photosynthesis Chlorophyll: It is the green pigment present in leaves in structures called chloroplasts. It is responsible for the absorption of sunlight. End product of photosynthesis 6CO2 + 12H20 C6H12O6+ 6O2 + 6H2O Reactions that take place during photosynthesis 1. 2. 3. 4. Absorption of light energy by chlorophyll. Conversion of light energy into chemical energy. Splitting of water molecule into hydrogen and oxygen. Reduction of CO2 to carbohydrates. Photosynthesis in dessert plants Desert plants take up carbon dioxide at night and prepare an intermediate which is acted upon by the energy absorbed by the chlorophyll during the day. Chlorophyll is necessary for photosynthesis 1. Take a potted plant like croton whose leaves are partly green and partly white 2. Place this plant in dark for three days 3. Take out the plant from the dark place and keep it in sunlight for 3 to 4 days 4. Pluck the leaf and boil it in water for a few minutes 5. Then boil it in alcohol so as to remove the green colour 6. Pour iodine solution on the colourless leaf and observe the change in colour of the leaf Observation The white parts colourless leaf doesn’t change blue black indicating there is no formation of starch. Whereas in the green parts of leaf changes indicating the presence of starch. This shows that chlorophyll is necessary for photosynthesis to make starch. Light is necessary for photosynthesis 1. Take a potted plant and place it in a dark room for 3 days. 2. Wrap the centre of one of its leaves with aluminium foil to prevent sunlight from reaching there 3. Place this plant in sunshine for 3 to 4 days. 4. Pluck the leaf covered with aluminium foil and remove its aluminium foil 5. Immerse this leaf in boiling water 6. Boil the leaf in alcohol to remove chlorophyll 7. Pour iodine on the leaf and observe the change in colour Observation The colour of the leaf in the corners change blue black indicating the presence of starch where as the colour of leaf at the centre doesn’t change. Hence light is necessary for photosynthesis. Heterotrophic nutrition (hetero-other) i. ii. iii. iv. Saprophytic Symbiotic Parasitic Holozoic –ingestion, digestion, absorption, assimilation, egestion Heterotrophic mode of nutrition in unicellular organisms. Amoeba: It is filled with a jelly like substance called cytoplasm. Finger like projections in amoeba called pseudopodia help in locomotion. It also helps amoeba engulf the food. Amoeba extends the pseudopodia around the food. The extensions fuse and form food vacuoles. These food vacuoles are structures that store food. The food is digested in the food vacuole and then travels outside into the cytoplasm. The remaining undigested food is thrown out of the cytoplasm. Paramoecium: cilia, definite shape. Digestive system Digestive system consists of a canal called alimentary canal 1) Moutha. Teeth: Teeth helps in chewing the food. We chew food so that the complex bigger molecules become softer and broken down into softer substances. b. Tongue: Tongue helps in moving the food inside our mouth and swallow the food c. Saliva: it is secreted by salivary gland. It consists of salivary amylase. It helps in moistening the food and break down carbohydrates. Enzymes; enzymes are biological catalysts that break down complex food substances into simpler molecules for absorption 2) Oesophagus – the oesophagus moves the food to the stomach. It performs peristaltic movement. The rhythmic contraction and relaxation of alimentary canal propelling the food forward from oesophagus to the stomach is called peristalsis. Presence of epiglottis here prevents the entry of food into the wind pipe. 3) Stomach- it is an extendable organ and j shaped organ. There are various secretion in the stomach a) HCL –It is secreted by the walls of the stomach. It is highly acidic. It is used to activate an enzyme called pepsin. It also kills harmful pathogens in our food when it reaches the stomach. b) Pepsin –It is used to break down proteins c) Mucus- HCL will damage or corrode the walls of the stomach. Inorder to prevent this there is a layer in the walls of the stomach which is called mucus. Mucus prevents HCl from corroding the walls of the stomach. d) Spincter muscle: it guides the entry of food from the stomach to the small intestine. ACIDITY: when we don’t have food for a long time the acid (HCL) in the stomach gets accumulated causing acidity in the stomach. 4). Small intestine –it is the longest section of the whole alimentary canal and is very highly coiled. This coiling is essential so that the food digested in the stomach stays in the intestine for a longer period of time and can be absorbed. It is differentiated into three regions – duodenum, jejunum, ileum. There are certain enzymes or juices secreted here. These are intestinal juice from the walls of the intestine, pancreatic juice from pancreas and bile juice from liver. a) Bile juice: It breaks down large fat globules into smaller globules and makes the food alkaline for pancreatic enzymes to act. b) Pancreatic juice: the pancreatic juice contains enzymes such as trypsin for digesting proteins and lipase for digesting emulsified fats. c) Intestinal juice: It converts proteins into amino acids, fats into fatty acids and glycerol and carbohydrates into glucose. d) Villi: the small intestine has small finger like projections called villi. They increase the surface area for absorption. The major portion of food is digested and absorbed in the small intestine. Herbivores have longer intestine than human beings because they eat grass which contains cellulose. So food should stay in the small intestine for a long time and get absorbed 5) Large intestine –water absorption takes place in the large intestine. The undigested food is passed out to the anus in the large intestine. Here there is a spincter muscle that regulates the exit of waste materials from the body out as faeces. Digestive glands. 1. Salivary glands –it secretes the 1st digestive juice. There are three pairs namely parotids, sub maxillary and sub lingual 2. Gastric glands –they are branched tubular glands which lie in the mucus membrane of stomach. They secrete gastric juices such as HCL, enzymes and mucus 3. Liver –it is the largest gland that lie below the diaphragm. Liver has right and left lobes. The cells of the liver are called hepatic cells and produce bile juice which flow out of liver through hepatic dust and opens into small intestine 4. Pancreas –it is a soft lobulated gland present between the lobes of duodenum. Name of secretion Site of the action gland Mouth Salivary Saliva gland Stomac h Enzymes Food acted End produce upon product d Salivary Starch Maltose amylase Gastric gland HCl, mucus Pepsin Liver Bile juice Small intestine fats Pancrea s Pancreati c juice Emulsifie d fats, proteins Small Trypsin, intestine lipase Proteins Peptons, polypeptide s Glycerol, fatty acids Dental caries –or tooth decay It causes gradual softening of enamel and dentine. I t begins when bacteria acting on the sugars produce acids causing to demineralise the enamel. Masses of bacterial cells together with food particles stick to the teeth to form dental plaque (sticky deposit). Saliva cannot reach the tooth surface to neutralise the acid because the tooth will be covered with plaque. Brushing the teeth after eating removes the plaque. If untreated, microorganisms may invade the pulp causing inflammation and infection. Respiration The process in which oxidation of organic compound occurs in cells and the energy is released Respiration is a chemical reaction whereas breathing is a physical reaction. Exchange of O2 and CO2 is called breathing. Breathing differs in different organisms. Various organisms have various organs to breathe. ORGANS Sponges, coelenterates, flatworms Earthworm Insects: spider, scorpion Cockroach Fishes, aquatic arthropods Amphibians Reptileas, birds, mammals Mallusca terrestrial forms ORGANISM Body surface Moist skin Tracheal tubes: book lungs Spiracles Gills Moist skin Lungs Lungs Stages of respiration There are three stages in respiration 1. External respiration; Gaseous exchange between environment and lungs. 2. Internal respiration: a) gaseous exchange between lungs and blood b) gaseous exchange between blood and tissues 3. Cellular respiration: oxidation of organic compounds in cell in which energy is released. C6H12O2 + 6O2 6CO2 + 6H2O + ATP Types of respiration Aerobic respiration Oxygen is used for the breakdown of glucose. In cellular respiration glucose combines with oxygen to give carbon dioxide, water and energy. This is called aerobic respiration. The respiration that takes place in the presence of oxygen is called aerobic respiration Anaerobic respiration Some organisms like yeast can respire in the absence of oxygen. Yeasts are unicellular organisms. Glucose doesn’t get oxygen and breaks down into ethanol, carbon dioxide and low amount of energy. The respiration that takes place in the absence of oxygen is called anaerobic respiration. “Yeasts are used in manufacturing of wine and beer as they produce alcohol during anaerobic respiration.” Respiration in muscles Muscles can respire anaerobically for a short period of time. This happens when there is lack of oxygen. Some activities like running, playing or doing heavy exercises require high energy. But oxygen is limited to produce large amount of energy. The glucose in the muscles produces lactic acid, carbon dioxide and less energy in this case. Cramps occur when muscles respire in the lack of oxygen. If a large amount of lactic acid is accumulated we get muscle cramps. This happens due to the incomplete break down of glucose. Hot water bath, hot compress or massage can relieve cramps. This is because they improve blood circulation. As a result oxygen in the blood will be available to muscle and lactic acid will be broken down into CO2 and H2O. Aerobic respiration Occurs in the presence of oxygen Complete oxidation of food takes place Releases more energy (38 ATP) Byproducts -CO2 & H2O Takes place in higher plants and animals Example: humans Anaerobic respiration Occurs in the absence of oxygen Partial oxidation of food takes place Releases less energy (2 ATP) Byproducts –ethanol Takes place in lower plants and animals Example: fermentation Respiration in plants Parts that participate in respiration’ Roots: Roots have tiny root hairs that are single cells. The air spaces between the soil help in respiration. Leaves : Leaves have tiny pores called stomata. These stomatal pores open and close for gaseous exchange to take place. It is the medium of exchange of gases in leaves. Glucose reacts with plants to give carbon dioxide, water and energy. Massive amounts of gaseous exchange takes place in the leaves through these pores for photosynthesis. Since large amounts of water can be lost in the stomata, the plant closes the pores when it doesn’t need CO2 for photosynthesis. Guard cells The stomata are covered by cells known as the guard cells that are responsible for the closing and opening of the pore. The guard cells swell when water flows into them causing the stomatal pore to open and the pores close when the guard cell shrinks. Human respiratory system 1. Nasal cavity: Nose has two openings called nostrils for the entry of air inside. The air is filtered by hairs and mucus. From here the air passes to the throat and then to the lungs. 2. Pharynx: It is a funnel shaped structure and common passage for the movement of food and air. 3. Larynx: It is the sound box. It is prominent in males 4. Trachea: The extension of larynx is a short tubular cartilaginous ring called trachea. It is also called the wind pipe. Rings of cartilage here prevent air from getting inside the food pipe. 5. Bronchi: The wind pipe externs further and divide into bronchi. Each bronchi further divides into bronchioles in the lungs 6. Lungs: Lungs are bag like structure present in the thoralic cavity. Each lung is covered externally by a double membrane and has a fluid filled cavity in between them. 7. Alveoli: Within the lungs the bronchioles end up in numerous air sacs called alveoli. The alveoli are balloon like structures and provide a surface for the exchange of gases. The walls of the alveoli contain an extensive network of blood capillaries that have low oxygen and high CO2 concentrations. This allows o2 to diffuse into the blood and CO2 to diffuse out of the blood easily. 8. Diaphragm: When we breathe in our ribs raise and diaphragm flattens and the chest cavity becomes larger causing the alveoli to expand. As a result the air is sucked into the lungs and fills the expanded alveoli. The blood brings CO2 from all parts of the body to the alveoli and the oxygen in the alveolar air is taken up by blood vessels to be transported to various cells in the body. During the breathing cycle when air is taken in and let out, the lungs contain a residual volume of air so that there is sufficient time for O2 to be absorbed and CO2 to be released. Difference between respiration in plants and animals Plants Animals Respiration takes place as a All the parts respire single unit individually Respiration occurs at a Respiration occurs at slow faster rate rate They produce more heat They produce little heat Transportation Blood and its composition Blood is the red colour fluid that flows in our blood vessels. It is composed of plasma, RBC, WBC and platelets. All these cells are produced in the bone marrow and released into the cell. Components of blood Cellular parts (45%) fluid (55%) RBC, WBC, Platelets Plasma RBC These are also known as erythrocytes. They are biconcave in shape. Mature RBCs lack nucleus. RBCs show the presence of haemoglobin. It transports oxygen to the required parts. Life span -120 days WBC These are known as leucocytes. They are of various types and shapes. Nucleus is present and they are colourless. They are known as the warriors of the human immune system. They protect us against various kinds of infections and pathogens and infections Platelets They are also called as thrombocytes. They are fragments of the cell and oval or round in shape. Nucleus is absent. It helps in clotting of blood. In case of injury, there is a rupture of blood vessels. So RBC, WBC comes out of the injured part. During that time platelets accumulate and help in clotting. Transfusion the transfer of blood from a healthy person to a patient is called transfusion. Plasma Plasma is mainly made up of water and proteins. Cellular parts such as RBC, WBC and platelets float in the plasma. It transports nutrients and waste materials Haemoglobin It is the red colour and respiratory pigment that imparts red colour to the blood. It is mainly made up of iron and proteins. Functions of blood It protects us from various kinds of pathogens and infections Blood helps in clotting when we get injured Blood helps in transportation of respiratory gases, nutrients. Blood removes waste materials such as urea from the liver to the kidney where it is excreted in the urine It also carries hormones from the endocrine glands to the target organs Blood regulates body temperature Lymph the fluid tissue Lymph is a fluid derived from the blood from plasma. It is more clear and watery than plasma. It seeps through the capillary walls to fill tissue spaces. This is known as the interstitial fluid or tissue fluid. Formation of lymph Water and other water soluble molecules move out into spaces between cells and tissues. Large proteins and formed elements stay in blood vessels. This results in the formation of lymph Composition of lymph It consists of water, ions and proteins such as antibody proteins, albumin, coagulation proteins, dissolved gases, nutrient molecules and lymphocytes. Lymphocytes are a part of WBCs. Functions of lymph They are important in body’s defence mechanism They filter out disease causing organisms and waste products like fragments of dead cells. It carries digested and absorbed fats from intestine It drains excess fluid from extra cellular space back into the blood. Structure of the heart The heart is present in between the lungs in the thoracic cavity. It is separated from the abdominal cavity by diaphragm. Our heart is hollow muscular organ. The size of the heart is as same as the size of our fist. Normal heart measures 12 cm in height and 9 cm in width. It is covered by a membrane called pericardium to reduce friction during heart beat and protect it from injuries External structure: it has 4 chambers which are divided by septum to prevent the mixing of pure and impure blood. The upper chambers are small in size and are called atrium The lower chambers are big as they supply blood and are called ventricles Internal structure: 2 auricles, 2 ventricles, blood vessels, valves and apertures. Atrium ; It’s the receiving chamber of the heart. It is thin walled. It is separated by intra atrial septum Ventricles: it’s the discharging chamber of the heart. It is thick walled because it pumps blood to all parts. They are separated by intra ventricular septum. Blood vessels: Superior venacava; it takes all the deoxygenated blood from the above region to the heart. From the head, neck etc., Inferior venacava: it takes all deoxygenated blood from the lower regions of the body such as legs etc., Systemic aorta: it is the largest artery of the human body. The oxygenated blood from the heart reaches all other organs through the aorta. Pulmonary artery: it takes impure blood from heart to lungs. All arteries carries pure blood except pulmonary artery Coronary artery: it supplies pure blood to the heart. If there is block age in the coronary artery we get heart attack. Valves: they prevent the back flow of blood. Two atrioventricular valves are present between chambers of the heart and the semilunar valves are present at the base of two large vessels pulmonary trunk and aorta. The contraction of the heart is known as systole and the relaxation of heart is known as diastole. Circulation in heart The right atrium contract and the blood is transferred from the right atrium to the right ventricle. The right ventricles relax when they receive blood. The right ventricle contracts and the blood is transported to the lungs for purification to the lungs. The pulmonary artery carries impure blood from the heart to the lungs. The pure blood from the lungs comes to the left atrium via pulmonary veins. The left atrium contracts and the blood is pumped to the left ventricles. The left ventricles relax and collects the blood. They then contract and blood is pumped to all the other organs through the aorta which is the largest artery Double circulation A circulatory system in which the blood travels twice through the heart in one complete cycle of the body In double circulation, there are 2 steps namely systemic and pulmonary circulation. From the body parts the impure blood reaches the right atrium through venacava. From the right atrium the blood reaches the right ventricle. From the right ventricle the blood reaches the pulmonary arteries carry the impure blood to the lungs. The lungs purify the blood by exchanging the gases. From lungs the pure blood reaches the left atrium through pulmonary vein. From the left atrium blood reaches the left ventricle. From the left ventricle blood reaches the body parts through aorta, which is the largest artery. This separation of right side and left side of the heart prevents mixing of oxy and deoxy blood. This allows High efficient supply of oxygen to the body Maintaining body temperature in birds and mammals which have high energy needs. No. Of chambers 2 3 4 Organism Fishes Amphibians and reptiles Birds and mammals Circulation in fishes and amphibians Fishes have 2 chambered hearts. Blood is pumped to the gills and oxygenated there. Oxy blood passes directly to all the other parts. Blood goes only once through the heart in one cycle. Therefore it is called single circulation. Animals like amphibians and reptiles which do not use energy for the maintenance of temperature Have 3 chambered hearts and tolerate some mixing of oxy and deoxy blood. Blood pressure Blood pressure it is the force or pressure on the walls of the artery. There is upper limit and lower limit for B.P. the upper limit is the systolic pressure and the lower limit is the diastolic pressure. When the ventricles contract the pressure in the walls of the artery is high and when the ventricles relax the pressure in the walls of the artery is less. The normal B.P rate is 120/80 mmHg. It is measured using sphygmomanometer. High B.P is caused by the constriction of arterioles, which results in increased resistance to blood flow. It can lead to the rupture of an artery and internal bleeding. High B.P –hypertension ; Low B.P –hypotension Blood vessels Arteries They have thick elastic walls Veins They have thin walls and valves They take blood from the heart to various organs They collect blood from various organs to the heart All arteries carry pure blood except pulmonary artery All veins carry impure blood except pulmonary vein The pressure of blood in the artery is very high. Therefore to prevent them from bursting they have thick walls. Capillaries On reaching an organ or tissue artery divides into smaller and smaller vessels called capillaries, the smallest vessels that are one cell thick to bring blood in contact with each and every cell. Exchange of materials between the blood and the surrounding takes place across capillaries. The capillaries then join together to form veins. Mechanism of clotting Thromboplastin + prothrombin + calcium = thrombin Thrombin + fribrinogen = fibrin Fibrin + blood cells = clot Thromboplastin –from injured tissue; Prothrombin –inactive thrombin present in plasma; Calcium –required for activating prothrombin fibrogen –soluble protein in blood plasma Transportation in plants Structure of roots Roots consist of small hair like structures which are known as root hairs. Root hairs are the smallest figures that absorb water. Root hairs are the elongation of the cell membrane of the outer surface of roots. There are many cells within the root hair in a region called cortex The final cell inside the root hair is known as the xylem. Water is transported from the roots to the leaves with the help of xylem through a process called osmosis. (OSMOSIS: The movement of water molecules from a higher concentration to a lower concentration through a semi permeable membrane) Semi permeable –any covering which would allow the passage of certain substances. The water is higher in the soil than in the root hair. Therefore water from the soil moves into the root hair. Once the root hair gets filled the water moves from the root hair into the cortex. Water from all the cells in the cortex move into the xylem. In the xylem tissue roots, stems and leaves are interconnected to form a continuous system of water conduction to reach all parts of the plants. There is steady movement of water into root xylem creating a column of water that is steadily pushed upwards. This pressure moves water over the heights from xylem in plants. Xylem is present in the centre and unidirectional. Xylem consists of tracheids, xylem parenchyma, xylem fibres and vessels. All cells are dead except xylem parenchyma Transportation of food in plants Food is produced in leaves through photosynthesis. This photosynthesis produces carbohydrates in soluble form. From the leaves the food will be transported to roots and stems downwards and to the upwards to the leaves and other parts through the phloem. This transport of soluble products of photosynthesis to various parts of the plant is called translocation. Translocation takes place in sieve tubes with the help of companion cells bidirectionally. Food is stored as energy in the form of starch in the roots –tubers. Tubers are roots in which energy is stored as starch. Ex: carrot, potato. Energy from the food is stored in some stems. Ex: ginger, turmeric. Phloem is present in the edges. The translocation in phloem is achieved by utilising energy. Materials like sucrose are transferred into phloem tissue using energy from ATP. This increases osmotic pressure in the tissues. Therefore water moves into phloem. This pressure moves the materials in the phloem to other tissues which have low pressure. In this way phloem transports food, amino acids and other substances according to the plant’s need. This transportation is called active transport as it utilises energy for transportation. The conducting cells in phloem are sieve tubes. They also have companion cells, phloem parenchyma and phloem fibres. All cells are living cells except phloem fibres. Transpiration Loss of water in the form of vapour through the aerial parts of the plant (stomata present in the leaves) is called transpiration. Transpirational pull: transpiration creates a suction which pulls up water from the xylem cells of roots Importance of transpiration Helps in absorption and upward movement of water and dissolved minerals from roots to leaves Helps in temperature regulation Diurnal variation Day- stomata is open. Transpirational pull is the major driving force in water movement in xylem. Night – root pressure is important factor in water transport. Excretion The biological process of removal of harmful metabolic wastes from the body is called excretion Cells of different organisms do different kinds of work and thus generate different kinds of waste. Metabolism –the sum of all chemical reactions inside a cell. Excretion in unicellular organisms Excretion is unicellular organisms are simple. Diffusion and osmosis are the two basic processes at cellular level. They help cells release or exchange substances within the surrounding. Every unicellular organism thus throws out the waste through osmosis and diffusion. Excretion in plants They are multicellular with simple organisation. They have ability to remove waste near the site where the waste is produced. Oxygen which is released as a waste during photosynthesis is directly released out by the stomata Other wastes such as resins, gums are accumulated in dead tissues such as the bark of the tree or the old xylem. Apart from this plants also store their cellular waste in the vacuole. They also accumulate wastes in the leaves that are about to die and fall down. Excess water is removed by transpiration. Plants also excrete some waste into the soil. Human excretory system Urea is the most toxic metabolic waste produced in a large quantity. Most of the metabolic reactions in our body include proteins or amino acids. The common waste produced by these metabolic reactions is ammonia. We can neither eliminate ammonia immediately nor store it. The liver absorbs the ammonia (more toxic waste) and converts it into urea (less toxic waste). The urea is then released into the blood. Structure of the kidney Kidney: Kidneys are bean shaped organs. They are located on either sides of the vertebral column at the back. This is why people suffering from kidney problems suffer from lower back pain. The central part of the inner side of the kidney is called hilum. Any substance entering or leaving the kidney passes through hilum. Blood vessels nerves and urether are connected to the kidney through the hilum. Blood vessels in the kidney There are 2 vessels in the kidney. The renal artery carried pure blood that contains urea to the kidney. The kidney will filter out urea and passes out pure blood. The renal vein carries pure blood without urea out of the kidney Internal structure Internally kidney is divided into 3 parts. The outermost region is called cortex. The middle region is called medulla. Medulla consists of multiple triangular structures called renal pyramid. The inner most region is called pelvis which directly connects to the urether. Blood travels 60 times a day through the kidney. Nephrons There are very tiny mysterious filters known as nephrons in the kidney. There are roughly 1 million nephrons in each kidney. If we place all the nephrons horizontally they will approximately cover about 16 kilometres. Nephrons are also known as kidney tubules. Bowman’s capsule Parts: Glomerulus, PCT, DCT, Henle’s loop and collective duct. It is a cup shaped organ consisting of a number of blood capillaries called glomerulus. The tubule near the Bowman’s capsule is the proximal convoluted tubule and that far from the Bowman’s capsule is called distal convoluted tubule. The u- shaped loop is called Henle’s loop and connects both PCT and DCT. Lastly there is a collective duct that collects waste products. Working of nephron Our kidney filters out urea continuously. They collect urea along with water and some salts which together forms urine. The blood with water salts nitrogenous wastes glucose amino acids etc., enters the nephron through the afferent artery. The filtration of blood takes place due to the pressure in the glomerulus and passes through the efferent artery. As a result salts, urea, amino acids, and large amount of water are filtered out. The filtrate moves down to the tubular part of the nephron where major parts of water, glucose and salts are selectively reabsorbed and thus urine becomes concentrated. Some substances may be secreted in the final secretion tubule. This final filtrate is now collected by the collecting duct of the kidney. From each kidney arises a narrow tube caller ureter whic connects the kidney and urinary bladder. The 2 tubes are about 80 cm in length and carry urine downwards and open to the urinary bladder. Each ureter opens into a muscular urinary bladder which opens to the outside of the body by a tube called urethra. The urinary bladder can hold about 0.5l of urine until its release. The urge to discharge urine is under nervous control Composition of urine and its regulation Urine is the translucent, pale yellow and slightly stinky substances that is excreted out of our body every few hours. Physical properties It is clear and pale yellow in colour due to presence of urochrome pigment. The intensity of yellow colour changes with the amount of water we drink. Urine is slightly acidic in nature with pH of 6 Its relative density is 1.03 to 1.04. Urine is odourless but can have a pungent smell of ammonia Any change in the physical properties is a sign of abnormality. Composition of urine 96 % water 2% ions like Na, 2% urea K, salts ammonia etc., Average urine output –1 –1.5l per day Consumption of more water: intensity of yellow colour will be less Consumption of less water: intensity of yellow colour will be more Artificial kidney (haemodialysis) If our kidney get affected there will be a problem in filtering out toxic wastes from our blood. In case of a kidney failure an artificial kidney can be used. Artificial kidney is a device used to remove nitrogenous waste products from the blood through dialysis. Working of artificial kidney Artificial kidneys contain a number of semi permeable lining suspended in a tank filled with dialysing fluid with the same osmotic pressure as that of blood. The blood contains nitrogenous wastes whereas the dialysing fluid does not. The patient’s blood is passed through these tubes. During this passage the waste products from the blood diffuses into the dialysing fluid. The purified blood is pumped back to the patient’s body. This is in similar to the function of the kidney but selective re-absorption doesn’t take place. In a healthy adult the volume of initial filtrate is about 180l. But the volume excreted is 1 –2 litre a day due to selective re-absorption.