CHAPTER 11 STUDY QUESTIONS updated spring 2019 See hormone table in your connect files. Know the endocrine glands, hormone it secretes, the targets and the hormone’s primary action. Most of chapter 11 test questions are matching hormones to glands to function etc. For example: Pancreatic beta cells secrete insulin which lowers blood glucose(how?) Another perspective is patient has elevated blood glucose which means they may have damage to ??? Also I will put some connect homework questions on test so review your homework. 1. What are the lipophilic hormones? What does lipophilic mean? -They are located in the cytoplasm or nucleus. Lipophilic means water-soluble 2. Why do they need carrier proteins? -because they cannot cross the plasma membrane 3. Where are lipophilic hormone receptors located versus nonlipophilic(protein) hormones? -Lipophilic receptors are located inside the cell and nonlipophilic are located outside the cell 4. Why are lipophilic hormones called transcription factors? -because they are activated by binding of the hormone and produce new proteins 5. Which type of hormones use second messengers? lipophilic or nonlipophilic -lipophilic 6. What is pulsatile secretion? 7. The anterior pituitary is also called the _______adeno______hypophysis. 8. The posterior pituitary is also called the _________neuro______hypophysis. 9. Know the relationship between the hypothalamus and the anterior/posterior pituitary. -Posterior stores and release 2 hormones (ADH and Oxytocin) made in the hypothalamus -Hypothalamus releases TRH into the anterior 10.What is the hypothalamo-hypophyseal portal system? -Axons of hypothalamo-hypophseal tract 11. What is the hypothalamo-hypohyseal tract? - ADH and oxytocin are transported along axons of the hypothalamo-hypophyseal to the posterior pituitary where they are stored 12. Know fig. 11.34 as far as the two enzymes that convert arachidonic acid to either leukotrienes or prostaglandin 13. In the endocrine system what defines a target tissue? -pancreas 14. What kinds of hormones are secreted by the hypothalamus? -ADH, Oxytocin 15. Most lipid soluble hormones (steroids) are derived from __cholesterol_. 16. Lipophilic hormones are nonpolar and hydrophobic with their receptors………17. 17. Protein hormones have their receptors where? -outside the cell 18. Steroid hormones have their receptors where? -within the nucleus 19. How do lipophilic hormones travel in the blood? Attached to carriers 20. What is the parent molecule for leukotrienes and prostaglandins? -leukotrienes, lipoxygenase -Prostaglandins, COX 21. NSAIDs produce their effects by inhibiting the _Cyclooxygenase_ enzyme