Arteriosclerosis vs Atherosclerosis http://www.mayoclinic.org/diseases-conditions/arteriosclerosisatherosclerosis/basics/definition/con-20026972 Arteriosclerosis occurs when the blood vessels that carry oxygen and nutrients from the heart to the rest of the body (arteries) become thick and stiff restricting blood flow to organs tissues. Commonly called hardening of the arteries. Atherosclerosis is a specific type of arteriosclerosis, but the terms are sometimes used interchangeably. Atherosclerosis refers to the buildup of fats, cholesterol and other substances in and on artery walls (plaques), which can restrict blood flow. “Regular daily exercise is a primary intervention for all types of peripheral arterial disease to promote development of collateral circulation and maintain tissue perfusion. Therefore, regular progressively strenuous exercise (30-45 min daily walking) is important. Rest with beginning of claudication, resume activities when pain resolves. (Lemone & Burke, 2008, p. 1176-77). Peripheral Vascular Disease (PVD) http://www.texasheart.org/HIC/Topics/Cond/pvd.cfm Related terms: PVD, peripheral arterial disease, PAD, venous thrombosis, deep vein thrombosis, DVT Peripheral vascular disease (PVD) involves damage to or blockage in the blood vessels distant from your heart—the peripheral arteries and veins. Your peripheral arteries and veins carry blood to and from your arm and leg muscles and the organs in and below your stomach area. PVD may also affect the arteries leading to your head. When PVD affects only the arteries and not the veins, it is called peripheral arterial disease (PAD). The main forms that PVD may take include blood clots (for example, deep vein thrombosis or DVT), swelling (inflammation), or narrowing and blockage of the blood vessels. Diseases of the arteries may lead to: arterial blockage including peripheral artery disease or PAD aortic aneurysms Buerger’s disease Raynaud’s Phenomenon Disease of the veins may lead to: venous blood clots including deep vein thrombosis PE phlebitis varicose veins Arterial Blockage What causes arterial blockage? PVD can result from a condition known as atherosclerosis, where plaque forms inside of the arteries. Clogged peripheral arteries in the lower part of the body (also referred to as peripheral artery disease or PAD) most often cause pain and cramping in the legs phlebitis varicose veins Arterial Blockage What causes arterial blockage? PVD can result from a condition known as atherosclerosis, where plaque forms inside of the arteries. Clogged peripheral arteries in the lower part of the body (also referred to as peripheral artery disease or PAD) most often cause pain and cramping in the legs. What are the symptoms and signs? Patients may feel pain in their calves, thighs, or buttocks, depending on where the blockage is. Usually, the amount of pain you feel is a sign of how severe the blockage is. In serious cases, toes may turn a bluish color, feet may be cold, and the pulse in legs may be weak. In severe cases, the tissue dies (this is called gangrene) and amputation may be needed. Sometimes leg cramps develop when a person walks, and the leg pain usually gets worse with increased activity. This cramping is called intermittent claudication. Like the chest pain of angina, the leg pain of intermittent claudication usually goes away with rest. Cold temperatures and some medicines may also cause leg pain. The main risk factor for PAD is smoking. Other risk factors include older age and diseases like diabetes, high blood cholesterol, high blood pressure, heart disease, and stroke. Many people who have PAD don't have any symptoms. If you have symptoms, they may include Pain, numbness, achiness, or heaviness in the leg muscles. This happens when walking or climbing stairs. Weak or absent pulses in the legs or feet Sores or wounds on the toes, feet, or legs that heal slowly, poorly, or not at all A pale or bluish color to the skin A lower temperature in one leg than the other leg Poor nail growth on the toes and decreased hair growth on the legs Erectile dysfunction, especially among men who have diabetes Lifestyle changes include dietary changes, exercise, and efforts to lower high cholesterol levels and HTN. http://www.nlm.nih.gov/medlineplus/peripheralarterialdisease.html What Is Peripheral Arterial Disease? (PAD) Peripheral arterial disease (PAD) is a disease in which plaque builds up in the arteries that carry blood to your head, organs, and limbs. When plaque builds up in the body's arteries, the condition is called atherosclerosis. Over time, plaque can harden and narrow the arteries. This limits the flow of oxygen-rich blood to your organs and other parts of your body. PAD usually affects the arteries in the legs, but it also can affect the arteries that carry blood from your heart to your head, arms, kidneys, and stomach. This article focuses on P.A.D. that affects blood flow to the legs. Peripheral arterial disease (PAD) is a disease in which plaque builds up in the arteries that carry blood to your head, organs, and limbs. When plaque builds up in the body's arteries, the condition is called atherosclerosis. Over time, plaque can harden and narrow the arteries. This limits the flow of oxygen-rich blood to your organs and other parts of your body. PAD usually affects the arteries in the legs, but it also can affect the arteries that carry blood from your heart to your head, arms, kidneys, and stomach. This article focuses on P.A.D. that affects blood flow to the legs. Although PAD is serious, it's treatable. If you have the disease, see your doctor regularly and treat the underlying atherosclerosis. PAD. treatment may slow or stop disease progress and reduce the risk of complications. Treatments include lifestyle changes, medicines, and surgery or procedures. Researchers continue to explore new therapies for P.A.D. http://www.nhlbi.nih.gov/health/health-topics/topics/pad/