Chapter 11: Human Reproductive System Name: _______________________________( ) Class: ______ Date: ____________ CHAPTER MAP & OVERVIEW Ch 11.1 THE HUMAN REPRODUCTIVE SYSTEM Anatomy and Function of Reproductive System Puberty Male 1. 2. 3. 4. 5. PostFertilization Female Testis Epididymis Sperm duct Glands Penis Structure of Gametes 1. Sperm 1. 2. 3. 4. 5. Ovary Oviduct Uterus Cervix Vagina Structure & Function of: 1. Placenta 2. Amniotic Sac 3. Amniotic Fluid 4. Umbilical Cord 2. Ovum Ch 11.2 SEXUALLY TRANSMITTED INFECTIONS Prevention Copulation & Fertilization Chapter 6.1.3 Menstrual Cycle Ch 11.3 ISSUES ON SEX & FERTILITY Family Planning Premarital Sex Birth Control Facilitated Reproduction Page 1 of 26 Ch 11.1 Human Reproductive System Learning Outcomes Students will be able to: 1. state some of the physical changes that occur during puberty and early adolescence. 2. label on diagrams of the male reproductive system and give the functions of: testes, scrotum, sperm ducts, prostate gland, urethra and penis. 3. label on diagrams of the female reproductive system and give the functions of: ovaries, oviducts, uterus, cervix and vagina. 4. compare the male and female gametes in terms of size, numbers and mobility. 5. describe the menstrual cycle with reference to the alternation of menstruation and ovulation, the natural variation in its length, and the fertile and infertile phases of the cycle with reference to - progesterone, oestrogen (IP Classes) - progesterone, oestrogen, follicle-stimulating hormone (LSH) and luteinising hormone (LH) (Advanced) . 6. recognise that in sexual reproduction a new individual is formed through the union of an egg and a sperm. 7. recognise that a new individual formed through sexual reproduction receives genetic information from its mother (via the egg) and its father (via the sperm). 8. describe fertilisation and early development of the zygote simply in terms of a ball of cells which becomes implanted in the wall of the uterus. 9. state the function of the amniotic sac and amniotic fluid. 10.describe the function of the placenta and umbilical cord in relation to exchange of dissolved nutrients, gases and excretory products (no structural details are required). Ch 11.2 Sexually Transmitted Infections Learning Outcomes Students will be able to: 1. state the harmful consequences of sexually transmitted infections like syphilis, gonorrhoea and AIDS. 2. explain that syphilis and gonorrhoea are caused by a bacterium which is transmitted during sexual intercourse. 3. describe the symptoms, signs, effects and treatment of syphilis, gonorrhoea and AIDS. 4. discuss the spread of human immunodeficiency virus (HIV) and methods by which it may be controlled. Ch 11.3 Issues on Sex and Fertility Learning Outcomes Students will be able to: 1. discuss the consequences and issues relating to abortion and pre-marital sex. 2. describe the following methods of birth control: natural, chemical (spermicides), mechanical, hormonal and surgical. Advanced 1. describe some forms of facilitated reproduction in human beings. E.g: IVF. Page 2 of 26 11.1 Human Reproductive System All living things reproduce. Reproduction is the biological process where new individuals (known as “offsprings”) are made from older ones (known as “parents”) Organisms reproduce by two primary means: (1) Sexual Reproduction Sexual reproduction is the biological process of forming a new individual through the fusion of the nuclei of two very specialized cells known as gametes. The fusion process is also known as fertilization. In cases where the two gametes involved in the fusion are distinct in form and structure, the larger of the two gametes is known as the egg or ovum, while the smaller one is known as the sperm. (2) Asexual Reproduction Asexual reproduction is the biological process of forming a new individual from a single parent without the involvement of gametes (i.e. without fertilization). The table below summarizes the differences between sexually and asexually reproducing organisms Feature Sexual Reproduction Asexual Reproduction No Requires fertilization? Yes Number of parents required Usually involves two parents but may occur within the body of a single hermaphroditic organism One (hermaphrodites are organisms with both male and female sexual organs) Variation in offspring? Produces genetic variation in offspring. (i.e. offspring may have genetic differences between one another) All offspring are genetically identical, and are also genetically identical to the parent Note that while some organisms reproduce either asexually or sexually, there are many organisms that are capable of reproducing in both manners. We will focus on discussing about sexual reproduction in human beings. Page 3 of 26 PUBERTY Puberty is the developmental process where a child’s body matures into an adult body where he or she is now capable of reproduction. This process is triggered by: 1. Release of hormones from the brain to the gonads. The gonads are the organs responsible for the production of sperm and eggs. In males, the gonads are the testes and in females, the gonads are the ovaries. 2. In response to the hormonal signals from the brain, the gonads begin secreting sex hormones (such as testosterone and oestrogen). 3. The gonads also initiate gametes production. In the testes, sperm are produced, while in the ovaries, eggs begin maturing (premature eggs are formed in the ovaries prior to birth). 4. Other secondary sexual characteristics also begin to develop. Secondary sexual characteristics are unique features found in each sex of a species of organisms and they only arise in a later part of the organism’s life cycle (i.e. puberty). In contrast, primary sexual characteristics refer to features that distinguish the two sexes from birth. For example, presence of testes or ovaries is a primary sexual characteristic as these organs distinguish a male from a female from birth. The table below describes some secondary sexual characteristics in males and females. Males Females Onset at age 11 to 15 years old Onset at age 9 to 13 years old Predominant growth of facial, underarm, chest, abdominal and pubic hair Predominant growth of underarm and pubic hair Broadening of chest and shoulders Broadening of hips Enlargement of penis and testes Enlargement of breasts Sebaceous (oil) and sweat glands become more active, leading to acne in severe cases Sebaceous (oil) and sweat glands become more active, leading to acne in severe cases Deepening of voice as larynx enlarges Increase in weight and height Increased muscles mass and strength; increase in height Page 4 of 26 ANATOMY AND FUNCTION OF THE HUMAN REPRODUCTIVE SYSTEM The male and female reproductive systems have distinctive features. In this section, we will examine the structure and function of the various organs in each system. A. The Male Reproductive System Fig. 1 Lateral view of the typical human male reproductive system. Image taken from Pearson Education. Structure Function 1) Testis • • Production of male gametes (sperm) Production of male sex hormones (testosterone) 2) Epididymis • • Temporary storage of sperms Muscles in epididymis contract to ejaculate sperms 3) Sperm duct • Transport sperms from the epididymis to the urethra • Production of seminal fluid - Alkaline to neutralize acidity in female reproductive tract - Activates sperms by causing them to swim freely - Nourish sperms with nutrients • Insertion into vagina when erected 4) Glands P Seminal vesicles P Prostate gland P Bulbourethral or Cowper’s glands 5) Penis Page 5 of 26 Fig.2 Frontal view of the typical human male reproductive system. Image taken from Pearson Education. Some physiological changes occur during sexual arousal leading to erection. The process is described as follows: Physiology of Erection and Ejaculation: 1) Arterioles bringing blood to the penis and its erectile tissue dilate. 2) Blood begin entering the erectile tissues and fills up the blood spaces in the erectile tissue. 3) Penis becomes turgid. 4) Epididymis contracts 5) Semen is released. Page 6 of 26 B. The Female Reproductive System Fig.3 Lateral view of the typical human female reproductive system. Image taken from Pearson Education. Fig.4 Front view of the typical human female reproductive system. Image taken from Pearson Education. Page 7 of 26 The table below lists the adaptation and functions of various organs in the female reproduction system: Structure Function OR Adaptation 1) Ovary • • Production of female gametes (ova) and release of mature ovum Production of female sex hormones (oestrogen and progesterone) 2) Oviduct • • • Deliver mature ovum from ovary to uterus Beating of cilia to move ovum along oviduct Muscular, strong contractions • • Muscular and elastic, to push foetus out during birth Soft and smooth endometrium prepares for implantation of embryo 3) Uterus 3a) Endometrium (Uterine lining) Structural Adaptations of the Male and Female Gametes The function of the male gamete, also known as sperm, is to deliver the male’s genetic material to the egg by fertilizing it. The function of the female gamete, also known as the ovum (plural: ova), is to contain the female’s genetic material and to be fertilized by one sperm. The diagram below illustrates the differences between the sperm and ovum: Fig.5 Structure of the sperm (left and the egg (right). Not drawn to scale. Sperm image taken from http://qwickstep.com/search/chromosomes-in-a-spermcell.html. Image of ovum from http://www.academiavita.org/immagini/Pubblicazioni/embrio/en glish/colombo/FIG6.JPG Page 8 of 26 The table below lists the structural adaptations of the sperm cell: Structure Adaptation • • 1) Acrosome • Contains acrosin, a protease enzyme, released by the sperm upon contact with the membrane surrounding the ovum. Acrosin aids in digesting away this membrane (known as zona pellucida) which surrounds the cell membrane of the ovum. This allows the sperm cell to penetrate the ovum during fertilization. • Contains the male genetic material that will eventually be combined with the female genetic material in the ovum during fertilization. • The thinner cytoplasm reduces resistance to the motion of the sperm towards the ovum. 4) Middle piece • • The middle piece consists of a spiral mitochondrion. The mitochondrion supplies energy for the beating of the tail. 5) Tail (or flagellum) • The tail beats to propel the sperm towards the ovum. 2) Nucleus 3) Minimal cytoplasm Some differences between the sperm and the ovum are listed in the next table: Sperm Feature 1) Shape 2) Size 3) Numbers 4) Motility 5) Lifespan Ovum • Three distinct regions, namely: head, middle piece and tail • Spherical • Small, head about 2.5 μm, full length about 40 μm • Large, about 120 μm • 200 to 500 million sperm cells per seminal discharge • One released on an average of about 28 days. • • Non-motile Swept along oviduct by cilia lining the walls of the oviduct or by contractions of the muscles in the oviduct walls • Only 48 hours (or less) if unfertilized • • Motile Move by beating of flagella • • Die rapidly in open air Die within a few hours in the vagina Lifespan of 2 to 3 days in the oviduct • Page 9 of 26 THE MENSTRUAL CYCLE Menstrual Cycle Video: http://www.youtube.com/watch?v=WGJsrGmWeKE http://www.bbc.co.uk/schools/gcsebitesize/science/aqa_pre_2011/human/hormonesrev3.shtml Oestrogen Fig.6 Menstrual Cycle Image taken from https://www.babycenter.com/ims/2018/06/833x469xbc-menstrual-cyclelogo_wide.png.pagespeed.ic.Pk7TLDetrQ.png • The menstrual cycle refers to a cycle of physiological changes that occur in a fertile woman’s reproductive system. This cycle of events is essential for reproduction to occur. • The average period of each cycle is about 28 days. • However, it may also range between 14 to 35 days, depending on stress levels and lifestyle. • The cycle is under the direct control of hormones. • In particular, progesterone and oestrogen. Page 10 of 26 Basic Information Advanced (Only Progesterone and Oestrogen) (More Details on LH and FSH) Menstruation, Day 1-5: • The first day of menstruation is the first day of menstrual cycle. • The unfertilized egg, together with the fragments of endometrial tissues, blood capillaries and blood, will be removed through menstrual bleeding as it flows from the uterus out of the body through the vagina. • The first day of menstruation is the first day of menstrual cycle. • The unfertilized egg, together with the fragments of endometrial tissues, blood capillaries and blood, will be removed through menstrual bleeding as it flows from the uterus out of the body through the vagina. • The anterior pituitary gland secretes FSH into the bloodstream which travels to the ovaries. Follicle Stage, Day 6-13: • Oestrogen causes the growth and repair of the uterine lining (endometrium). Effects of FSH: • FSH stimulates the development of the follicles in the ovaries. • One follicle will become the Graafian follicle. • FSH also stimulates the follicles to secrete oestrogen. Effects of Oestrogen: • Oestrogen causes the growth and repair of the uterine lining (endometrium). High Concentration of Oestrogen: • When oestrogen levels increase to a high level, it inhibits the secretion of FSH, thus preventing the development of more follicles. • It triggers the secretion of LH from the anterior pituitary gland that travels in the blood to the ovaries. Ovulation, Day 14 • A sudden surge in LH triggers the release of the mature ovum from one of the ovaries. • The mature ovum then begins its passage through the oviduct towards the uterus. • Upon release from the ovary, the mature ovum may only survive for 48 hours or less if it is not fertilized. Effects of LH: • LH causes ovulation. • It causes the follicular wall of the Graafian follicle to rupture, releasing the mature ovum from one of the ovaries into the oviduct (ovulation). • LH causes the formation of an active corpus luteum from the ruptured follicle. • The corpus luteum secretes progesterone and also some oestrogen. Page 11 of 26 • The mature ovum then begins its passage through the oviduct towards the uterus. • Upon release from the ovary, the mature ovum may only survive for 48 hours or less if it is not fertilized. Corpus Luteum Stage, Day 15 to 28 Effects of Progesterone • The high concentrations of progesterone encourages the proliferation (i.e. growth) of the uterine lining (or endometrium). • The progesterone maintains the thickened uterine lining (endometrium) by causing it to further thicken, well-supplied with blood capillaries (vascularized) in the endometrial tissues. • Eventually, it will reach maximum thickness. Effects of Progesterone • The high concentration of progesterone encourages the proliferation (i.e. growth) of the uterine lining (or endometrium). • The progesterone maintains the thickened uterine lining (endometrium) by causing it to further thicken, well-supplied with blood capillaries (vascularized) in the endometrial tissues. • Eventually, it will reach maximum thickness. • The thickness of the uterine lining is maintained mainly by the relatively high concentrations of progesterone. • The thickness of the uterine lining is maintained mainly by the relatively high concentrations of progesterone. • The proliferation of the uterine lining is to prepare for the implantation of the fertilized egg. • The proliferation of the uterine lining is to prepare for the implantation of the fertilized egg. If fertilization does not occur, • the production of progesterone will fall sharply and stop, thus the uterine lining cannot be maintained in a thickened state anymore, so it breaks down. • The unfertilized egg, together with the fragments of endometrial tissues, blood capillaries and blood, will be removed through menstrual bleeding. • Thus, this marks the beginning of a new cycle. • Progesterone also inhibits FSH and LH production (ovulation). • It also stimulates the formation of glands secreting nutrients to prepare the endometrium for the implantation of the embryo if there is fertilization. If fertilization does not occur, • the drop in LH level in the blood causes the corpus luteum to break down. • When this happens, the progesterone production stops, thus the uterine lining cannot be maintained in a thickened state anymore, so it breaks down. • The unfertilized egg, together with the fragments of endometrial tissues, blood capillaries and blood, will be removed through menstrual bleeding. • Thus, this marks the beginning of a new cycle. Page 12 of 26 If fertilization occurs, • the menstrual cycle is disrupted. • the fertilised egg becomes a zygote and the zygote develops into an embryo which implants itself in the uterine lining. • The embryo produces a hormone, hCG (human chorionic gonadotrophin), which prevents the corpus luteum from breaking down so that the corpus luteum continues to secrete progesterone and oestrogen until the placenta takes over the production of these hormones. To penetrate the ovum, the acrosome of the sperm release acrosine to disperse the follicle cells and digest away the membrane. Only one sperm nucleus enters the ovum. The haploid sperm nucleus fuses with the haploid ovum nucleus to form a fertilised ovum known as zygote (diploid). As soon as the sperm cell has entered the ovum, the membrane of the ovum changes such that no other sperms can enter. The remaining sperms which do not fertilise the ovum will eventually die. Take Note: As the average lifespan of the sperm cell in the oviduct is about 72 hours or about 3 days, any deposition of semen into the female reproductive tract 3 days prior to ovulation may suggest that the woman can still conceive if she ovulates on Day 14. Page 13 of 26 COPULATION & FERTILIZATION • Copulation or sexual intercourse refers to the process of placing the male genitalia into the female reproductive tract. • Fertilization on the other hand refers to the fusion of the male and female gametes, restoring the diploid number of chromosomes in the zygote. • It is important to distinguish the two processes. • i.e. Copulation does not necessarily lead to fertilization!! Fertilization is the process involving the fusion of the nuclei of male and female gametes to form the zygote. This process restores the diploid number of chromosomes. What are chromosomes? • Chromosomes are structures found in the nucleus of most body cells prior to cell division. • They contain hereditary information in the form of genes. • This genetic information is critical for determining the structure of and processes occurring in an organism and is being passed on from generations to generations. • Alteration to this information can be lethal or may lead to mutations. What is meant by the diploid number of chromosomes? • Most ordinary cells in your body possess the same number of chromosomes. • In the case of human beings, this number is 46 chromosomes (or 2 sets of 23 chromosomes). Any cells possessing two sets of these 23 chromosomes are described as having the diploid number of chromosomes. • However, gamete cells (ie. the sperm cell and the egg cell) only possess 1 set of 23 chromosomes. We describe these cells has having the haploid number of chromosomes. • Thus, when two haploid cells, the sperm and the egg, fuse, the resulting cell, known as a zygote, will thus possess the complete 46 chromosomes. We hence describe fertilization as a process that restores the zygote with the diploid number of chromosomes. • Note that different species have different diploid number of chromosomes. • The zygote, now with 46 chromosomes, will divide repeatedly, giving rise to all the body cells that will form the new individual. Each of these body cells will then have the diploid number of chromosomes (except for the gametes). • Note that this individual will also possess 23 chromosomes from the father and 23 chromosomes from the mother. • Thus, the individual will possess a mixture of characteristics or traits from either parent. Page 14 of 26 POST- FERTILIZATION • After the formation of the zygote, several cycles of cell division of the zygote occurs. • Eventually, the zygote forms a ball of undifferentiated cells. • This ball of cells then begins to form simple tissue layers and is now known as an embryo. • In later stages of development, the embryo starts to form distinguishable organs and we term this as the foetus. • The foetus is nourished and protected by several structures found in the uterus. • The following section describes these structures. Fig.7 Post-fertilization developments. th Image taken from Integrated Principles of Zoology, 13 ed., McGraw-Hill Companies (2006) Page 15 of 26 A. Amniotic Sac and Amniotic Fluid • The amniotic sac encloses the foetus in the amniotic cavity, which contains the amniotic fluid. • Functions of the amniotic fluid: o supports and cushions the foetus while in the uterus o absorbs shock, for example, if the mother has a fall o protects the foetus against physical injury as it cannot be compressed o acts as a lubricant and reduces friction in the birth canal during birth o allows foetus to move freely during gestation B. The Placenta • The fetal blood system must be separated from the maternal’s system as the two systems are functioning at different blood pressure. • The foetus’ blood type may also be different from that of the mother. Mixing of blood of different blood types may result in agglutination and this can be fatal. • Functions of the Placenta: o allows oxygen and nutrients (glucose, amino acids and mineral salts) to diffuse from the mother’s blood into the foetus’ blood o allows excretory products (urea and carbon dioxide) to diffuse from the foetus’ blood into the mother’s blood o allows antibodies (protection against diseases) to diffuse from the mother’s blood into the foetus’ blood o produces progesterone which maintains the uterine lining during pregnancy Page 16 of 26 C. The Umbilical Cord • The umbilical cord attaches the foetus to the placenta • It contains 2 umbilical arteries and 1 umbilical vein • Functions of the Umbilical Cord: o umbilical arteries transport deoxygenated blood and metabolic wastes products (urea) from foetus to the placenta o umbilical vein transports oxygenated blood, nutrients (glucose, amino acids) and other useful substances (antibodies, hormones) from the placenta to the foetus Page 17 of 26 11.2 SEXUALLY TRANSMITTED INFECTIONS (STIs) • Sexually transmitted infections (STIs) refer to o diseases transmitted mainly through sexual intercourse o caused by bacteria and viruses o affect the reproductive system (may also affect other body parts) o may not show visible signs or symptoms à pass on the disease unknowingly to their partners. o infections can be fatal o Examples:, Syphilis, Gonorrhoea, Acquired Immunodeficiency Syndrome (AIDS) Page 18 of 26 The table below summarizes some of these diseases’ cause, transmission, symptoms, effects and treatment: STI Gonorrhoea Cause Spherical bacteria Transmission • sexual intercourse with infected partner • from infected mother to baby during birth Symptoms • • painful sensation during urination discharge of pus from vagina or penis • • • sharing of injection needles with infected person Retrieved from: http://www.medicaldaily.com/gonorrheasuperbug-hits-australia-powerful-newstrain-cant-be-treated-regular-std-drugs299952 Syphilis Spiral bacteria Effects • • • transfusion of infected blood • • Human Immunodeficiency Virus (HIV) • • • • • Retrieved from: http://www.daviddarling.info/encyclopedia/ A/acquired_immune_deficiency_syndrome .html • Antibiotics, but some strains of the bacteria have developed drug-resistance painless sores on penis, vagina, cervix or mouth non-itchy skin rashes • • • • • deformed joints paralysis insanity death new-born may be deaf or with abnormal teeth and bone • Antibiotics, only effective at early stage weaken immune system loss of appetite and weight diarrhoea night sweat flu-like symptoms • immune system fails pneumonia tuberculosis brain infection Kaposi sarcoma • Currently, no cure. Cocktail of antiretroviral drugs is used to prolong lifespan and improve quality of lives of patients Post-exposure prophylaxis (PEP) can be used within 72 hours after a possible exposure to HIV. PEP is very effective but will not prevent 100% of HIV transmissions from occurring Retrieved from: http://www.3d4medical.com/Syphilis-45image_RM4698.html Acquired Immune Deficiency Syndrome (AIDS) Treatment infection of urethra infection of oviducts which may lead to infertility ectopic pregnancy infection of newborn’s eyes which may lead to blindness • • • • • Page 19 of 26 For your information only (a.k.a. not tested): HIV infects the helper T cells, macrophages and dendritic cells (different types of white blood cells in the immune system). The viral particles bind to these cells and enter the cells, utilising the cell’s mechanism in making copies of the viral genome and proteins. The viral particles are then assembled and exit the cells to infect more target cells. PREVENTION OF STIs • To reduce the risk of contracting AIDS and control its spread, o practice monogamy or abstinence o wear a condom during intercourse o do not abuse drugs o do not share instruments that break the skin (toothbrush, razors, piercing o needles, tattoo needles) and may be contaminated with blood o go to reliable practitioners who use sterilized/disposable instruments Page 20 of 26 11.3 ISSUES ON SEX & FERTILITY FAMILY PLANNING • • • Family planning is the process involving the planning of when and how many children to have. It often involves the use of various birth control methods for the implementation of the plans. Poor family planning may lead to unwanted or unplanned pregnancies. This has the following consequences: o Financial cost of raising the child o Psychologically not ready to start a family o Struggling with career and family commitments o Individual aspirations or pursuits PREMARITAL SEX • • • • • • Premarital sex refers to sexual intercourse between a couple who are not married. If the couple are teenagers, the consequences are direr. Engaging in sexual intercourse with a teenage girl (below 16 years old) is a crime, even if the girl gave her consent. Premarital sex may also lead to unwanted or unplanned pregnancy. Teenagers, being mentally, emotionally and financially not ready, are not able to cope well with pregnancy and child-rearing. Some even become infected with STIs. Options for teenage pregnancy • Teenage girls who get pregnant have the following option: o carry on with the pregnancy and keep the baby o carry on with the pregnancy and later give the baby up for adoption o have an abortion • Each of the above options has its inherent problems: o keeping the baby means that the girl has to stop schooling to look after the baby herself or she may have to start looking for a job to pay for the increased expenditure o giving up the baby for adoption can be emotionally traumatizing o getting an abortion (even if done professionally) can be risky: Ø infections of the uterus or oviducts which can lead to infertility Ø accidental puncturing of the uterus which can lead to heavy bleeding or infertility Ø weakening of cervix and uterus, especially if abortion is done repeatedly Ø increased risk of ectopic pregnancy Ø sense of loss, guilt, regret and depression • Although not encouraged, abortion is still carried out for various other reasons: o foetus is abnormal o mother’s life is endangered if the pregnancy continues o unwanted pregnancy resulting from rape o unfavourable conditions such as low family income or inadequate housing Page 21 of 26 BIRTH CONTROL • Couples practice birth control for various reasons: o Prevent unwanted pregnancy. o Family may be financially not ready. o Couple may want to pursue career development and do not have time for a child. o Family may already have enough children. o Couple may want to space out the age-gap of their children. o The woman may be ill and physically unsuitable to go through a pregnancy (egg Diabetic / High Blood Pressure). o Reduce risk of being infected with STIs. Page 22 of 26 Options for Birth Control • There are many options for birth control. Some forms of birth control only prevent pregnancy temporarily. Once the couple stops practicing these methods, they are able to get pregnant again. • Permanent birth control, once executed, is irreversible. The couple cannot have a baby again. • Medical developments had yielded more and more effective methods of birth control. • Below are examples of some common methods. * You may want to research on newer methods such as “Essure” / “The Patch”. Types of birth control Natural Chemical Examples Rhythm method Temporary / Permanent Temporary Withdrawal method Temporary Spermicide Temporary How it works Effectiveness The woman tracks her menstrual cycle and avoids having intercourse during the fertile period. Unreliable. The menstrual cycle is easily disrupted by hormonal fluctuation in the woman’s body. The man withdraws his penis just before ejaculation and sperms are not released into the vagina. A chemical is sprayed in the vagina to kill the sperms upon entry and render them unable to swim up to the oviducts. Unreliable. Sperms may be present in pre-seminal fluids and the man may not be able to withdraw in time. 80%. Some sperms may be resistant to the spermicide and can survive the journey towards the oviducts. Page 23 of 26 Types of birth control Mechanical Hormonal Examples Condom Temporary / Permanent Temporary How it works Effectiveness A rubber sheath is worn over the penis during intercourse and sperms are collected in the condom so that they cannot enter the vagina. 99.9%. Microscopic tears may be present and sperms may leak through. Diaphragm Temporary A rubber cap is fitted over the cervix and act as a barrier between the sperms and the ovum. 99.9%. If the cap is not fitted properly, sperms can still enter the uterus and swim up to the oviducts. Intrauterine Device (IUD) Temporary An IUD is a small t- 99% shaped device that is made out of flexible plastic. The t-shaped device is inserted into a woman’s uterus to prevent pregnancy. Pill Temporary Contains synthetic female hormones that prevent ovulation. Injection/Implant Temporary Synthetic female hormones are regularly injected directly or slowly released from an implanted tube into the blood stream to prevent ovulation. 99.9%. Women were reported to be impregnated even though they were put on the Pill. 99.9%. Women were reported to be impregnated even though they were put on hormonal treatment. Intrauterine Device (IUD) to be inserted into the uterus by a doctor. Image retrieved from: https://www.saintlukeskc.org/health-library/birth-control-iud-intrauterine-device Page 24 of 26 Types of birth control Surgical Retrieved from: Examples Ligation Temporary / Permanent Permanent How it works The oviducts are cut and tied up to prevent the sperms from meeting the ovum. Effectiveness 100%. http://www.coastalfertilityspecialists.com/coastalfertility/files/ff/ff25e278-7f1f-4ec6-9d0f- 440dadb0aa30.jpg Surgical Vasectomy Permanent The sperm ducts are cut and tied to prevent sperms from being released into the urethra and out of the penis. 100% Retrieved from: https://commons.wikimedia.org/wiki/File%3AVasectomy_diagram-en.svg Page 25 of 26 Facilitated Reproduction There are couples who are not able to have children due to various physical conditions: o o o o o o The ovaries may be defective The oviducts may be blocked The uterus/cervix may be too weak to sustain a pregnancy The sperms may be weak The man is unable to sustain an erection for penetration The woman may be suffering from other medical conditions (eg Diabetes or High Blood Pressure) which makes it difficult for her to conceive As a result, these couples may turn to facilitated reproduction: o o o In vitro Fertilisation (“Test tube baby”) In situ Fertilisation Surrogate mother In vitro Fertilization • • • • • • The woman is given hormonal treatment to stimulate multiple ovulation and the ova are harvested and screened for vitality. The sperms are also collected from the man and screened for vitality. A healthy sperm is then used to fertilise one ovum in a petri dish with the help of the microscope. The resulting zygote is allowed to divide before it is introduced into the uterus. Usually, up to 3 zygotes are introduced to increase the chances of successful implantation. If the zygote is successfully implanted, it can develop into an embryo and after 40 weeks, the foetus is ready for birth. Page 26 of 26