DATE: UNIT 2 NAME: Unit 2 Summary CLASS: BLM 2-1 Goal • Use this summary to review the concepts in Unit 2, Reproduction. Chapter 4 The nucleus controls the functions of life. Chromosomes found within the nucleus contain the genes that store the information to make proteins. (4.1) Proteins control the activities of cells. (4.1) RNA carries the message out of the nucleus to the ribosomes, which function to make proteins. (4.1) A gene mutation is a change in the order of the A, G, C, and T bases. (4.2) Gene mutations can have a positive, negative, or neutral effect on the individual. (4.2) Mutations can occur when DNA is being made or can be caused by mutagens. (4.2) Gene therapy attempts to correct gene mutations. (4.2) Chapter 5 Mitosis is the basis of asexual reproduction. There are three stages to the cell cycle: interphase, mitosis, and cytokinesis. (5.1) There are four phases to mitosis: prophase, metaphase, anaphase, and telophase. (5.1) Checkpoint proteins instruct the nucleus whether to proceed through the cell cycle. (5.1) An error in a checkpoint protein can cause diseases such as cancer, which is the result of uncontrolled cell division. (5.1) Asexual reproduction requires only one parent, and the resulting offspring are genetically identical to the parent. (5.2) Types of asexual reproduction include: binary fission, budding, fragmentation, vegetative reproduction, and spore formation. (5.2) Human-assisted plant and animal cloning methods can be used to save the genetic information of endangered species or to produce an organism with a desired trait. (5.2) Chapter 6 Meiosis is the basis of sexual reproduction. Meiosis produces gametes with half the number of chromosomes as body cells. (6.1) In meiosis I, homologous chromosome pairs line up at the equator, separate, and then move to opposite poles of the cell. (6.1) In meiosis II, chromosomes move to the equator and sister chromatids move to opposite poles of the cell. (6.1) The process of meiosis creates variation in organisms because genetic information is shuffled during meiosis I. (6.1) Chromosome mutations can occur during meiosis and can cause genetic disorders. (6.1) The three stages of sexual reproduction are mating, fertilization, and development. (6.2) For sexually reproducing plants and animals, there are two ways for a sperm cell and an egg cell to meet—through either internal or external fertilization. (6.2) The early development of an organism takes place during a stage called embryonic development. (6.2) Assisted reproductive technologies enable infertile couples to have children. These technologies have an impact on society (6.3) Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: UNIT 2 CLASS: Unit 2 Words to Know BLM 2-2 Goal • Use this page to review the Unit 2 Words to Know. Chapter 4 Chapter 6 chromosome DNA (deoxyribonucleic acid) gene gene mutation gene therapy mutagen negative mutation neutral mutation nucleolus nucleus positive mutation protein differentiation diploid number embryo embryonic development external fertilization fertilization gametes genetic diversity haploid number homologous chromosomes internal fertilization mating meiosis sexual reproduction zygote Chapter 5 asexual reproduction binary fission budding cancer cell cycle clone cytokinesis fragmentation interphase mitosis replication spindle fibres spore stem cell vegetative reproduction Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 4 Parts of the Cell CLASS: BLM 2-3 Goal • Review the parts of a plant cell and an animal cell. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-3 continued What to Do Label each cell part. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 4 CLASS: Functions of Cell Organelles BLM 2-4 Goal • Review the functions of cell organelles. What to Do Complete the following chart on cell organelle functions before you read pages 122–124 in your student book. Then check your responses as you read. Add any new information you gain in your reading in another colour of pen or pencil. Functions Cell Organelle Before Reading After Reading Cell membrane Cell wall Cytoplasm Mitochondria Chloroplast Ribosome Endoplasmic reticulum Vesicles Golgi body Vacuole Nucleus Nuclear membrane Nucleolus Cell membrane Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 4 CLASS: BLM 2-5 Cell Organelles Goal • Review cell parts and functions. What to Do Complete the following table by filling in the correct cell part or function. Cell Part Function Gel-like material inside cells Directs cell activities Endoplasmic reticulum Manufactures substances important for cell functions Releases energy in the cell Chromatin Chloroplast Stores water, food, and waste products Golgi body Digests wastes Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 4 CLASS: Modelling DNA BLM 2-6 Goal • Use these models of DNA to complete Activity 4-1C, Modelling DNA. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-6 continued What to Do • Develop your own model of DNA. Follow the instructions below. • The completed model should look like a ladder. Matched bases form the rungs. Besides being shaped like a ladder, a real DNA molecule would be twisted like a spiral staircase. Materials • paper models • scissors Safety Be careful when handling sharp or pointed objects. Procedure 1. Cut out the nucleotide models. Cut only on solid lines. 2. Fit eight nucleotide molecules together in puzzle-like fashion to form a row. Use the following sequence from top to bottom: • cytosine nucleotide • thymine nucleotide • guanine nucleotide • adenine nucleotide • guanine nucleotide • cytosine nucleotide • thymine nucleotide • adenine nucleotide 3. The above arrangement represents the left half of the ladder of DNA. Complete the right side of the DNA ladder by matching the shapes of the rungs. It may be necessary to turn molecules upside down in order to join certain base combinations. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 4 CLASS: Extracting DNA from Strawberries BLM 2-7 Goal • Use this flowchart before you do Activity 4-1D to help you understand the procedure for DNA extraction. What to Do The first step in DNA analysis in a crime or genetics laboratory is DNA extraction. Read the Find Out Activity on page 153 of your student book, and then complete the flow chart below. Take 1 frozen strawberry. 1. Put into a 2. Add (a) (b) (c) 3. Seal the bag. Gently crush the contents. Keep at room temperature and wait ____ min. 4. Fill a test tube about _______ full of strawberry solution. 5. Pour the __________ rubbing alcohol or ethanol into a______________. 6. Slowly pour a _________ of the rubbing alcohol or ethanol into the test tube until it is _______ full. Observe the DNA. Record your observations. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 4 Making Predictions about Mutations CLASS: BLM 2-8 Goal • Use this page to make predictions about mutations. What to Do Make predictions about what the following terms mean. Give an example if possible. Then read the student book pages 138–143. Confirm or correct your predictions. Term Before Reading What I Think the Term Means/Example After Reading What the Term Means/Example Positive mutation Negative mutation Neutral mutation Mutagen Gene therapy Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 4 Chapter 4 Quiz CLASS: BLM 2-9 Goal • Check your understanding of Chapter 4. What to Do Circle the letter of the best answer. 1. The function of the nucleolus is A. to protect the nucleus B. to protect the chromosomes C. to make ribosomes D. to make DNA 2. Which of the following organelles does not have a membrane? A. mitochondrion B. vesicle C. vacuole D. ribosome 3. Which one of the following statements is not true? A. A gene stores the information to make a particular protein. B. All the genes within the nucleus of a cell will be copied to make a protein at some time in the life cycle of a cell. C. Different types of cells in your body contain the same genetic information. D. Different proteins have different sequences of bases. 4. The function of the Golgi body is A. to receive vesicles from the endoplasmic reticulum B. to send vesicles to the endoplasmic reticulum C. to receive messages from the nucleus D. to send messages to the nucleus 5. Which of the following steps for the production of a protein is incorrect? A. The DNA message for a protein is copied into RNA. B. The nucleus receives a chemical signal to make a specific protein. C. The manufactured protein enters the endoplasmic reticulum. D. DNA leaves through the nuclear pore. 6. Chromatin is A. a substance that contains several molecules of DNA within each strand B. a substance within the nucleus that contains DNA and proteins C. a substance that unfolds before cell division D. a segment of DNA that codes for a particular protein Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-9 continued 7. A gene mutation is A. a change in the specific order of the A, G, C, and T bases that make up a particular protein B. a change in the specific order of the sugar and phosphates that make up a particular protein C. a substance that changes the DNA structure D. a substance that causes genes to be copied incorrectly 8. Gene therapy is not used as frequently as drug therapy or surgical therapies because A. the technique is too expensive B. viruses for the procedure are not easily available C. healthy genes are not easily available D. the healthy gene must be switched on in the correct cells 9. Cystic fibrosis is A. an example of a neutral mutation B. an example of a positive mutation C. an example of a negative mutation D. the result of the substitution for the base A for the T base in only one position on the gene 10. The white coat of the Spirit Bear is because of a A. positive mutation B. neutral mutation C. negative mutation D. gene therapy Match the Term on the left with the best Descriptor on the right. Each Descriptor may be used only once. Term Descriptor _____ 11. mitochondria A. sorts and packages proteins for transport _____ 12. chloroplast B. ribosomes attach here _____ 13. nucleus C. produces sugar for cell _____ 14. nucleolus D. changes sugar into useful energy for cell _____ 15. Golgi body E. ribosomes made here _____ 16. endoplasmic reticulum F. contains information to make proteins G. surrounds the cell membrane Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-9 continued 17. Explain how the nucleus controls the activities within a cell. _____________________________________________________________________________ _____________________________________________________________________________ _____________________________________________________________________________ 18. What are three causes of gene mutations? _____________________________________________________________________________ _____________________________________________________________________________ _____________________________________________________________________________ 19. Construct a flow chart that outlines how a protein is made. Use the terms below. Use additional words to connect the terms. DNA, endoplasmic reticulum, Golgi body, nuclear pore, ribosomes, RNA, vesicle Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 From One Cell to Many Cells CLASS: BLM 2-10 Goal • Use this chart to help you complete Find Out Activity 5-1A, From One Cell to Many Cells. What to Do Calculate how many skin cells will result from just 1 cell that continually divides during a period of 30 days. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 CLASS: Stages of the Cell Cycle BLM 2-11 Goal • Use this page to help you learn about the stages of the cell cycle. What to Do Complete this worksheet while you read about the stages of the cell cycle. You do not have to add any notes to the shaded boxes. Name of Cell Cycle Stage Cell Activities Nucleus Activities Interphase Growth and preparation Replication Continued growth and preparation Mitosis Early prophase Late prophase Metaphase Anaphase Telophase Cytokinesis Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 CLASS: BLM 2-12 The Cell Cycle Goal • Review terms and concepts about the cell cycle. What to Do Match the Statements on the left with the correct Phase on the right. Each Phase may be used more than once. Statement Phase _____ 1. nucleolus appears within each new nucleus A. prophase _____ 2. centromeres divide B. metaphase _____ 3. chromosomes become visible C. anaphase _____ 4. spindle fibres begin to form D. telophase _____ 5. DNA replicates E. interphase _____ 6. replicated strands move toward opposite poles _____ 7. chromosomes form a line across the middle of the cell _____ 8. nuclear membrane forms around each set of chromosomes _____ 9. cell grows 10. Place a check mark (9) under each phase in which you can see the structures listed in the first column. Structures Present Interphase Prophase Metaphase Anaphase Telophase Nucleus Nucleolus Nuclear membrane Chromatin Chromosomes Spindle fibres 11. Describe the end result of mitosis. _____________________________________________________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 CLASS: Steps of Mitosis BLM 2-13 Goal • Identify the phases of mitosis. What to Do In the boxes below • name each phase of mitosis • draw what is happening in the phase • describe what is happening in the phase Phase 1: _____________________________ Phase 2: _____________________________ Description: ________________________ Description: ________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ Phase 3: _____________________________ Phase 4: _____________________________ Description: ________________________ Description: ________________________ ___________________________________ ___________________________________ ___________________________________ ___________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 Cell Growth and Division CLASS: BLM 2-14 Goal • Review your understanding of the phases of the cell cycle. What to Do Write the name of the stage of the cell cycle that corresponds to each event described below. 1. Centromeres divide. ________________ 2. Centrioles move to opposite ends of the cell. ________________ 3. Nuclear membranes form around each mass of chromosomes. ________________ 4. Chromosome strands separate and move toward opposite ends of the cell. ______________ 5. A copy of each chromosome is made. ________________ 6. Cell membrane pinches together and the cytoplasm of the cell divides. _________________ 7. The nuclear membrane disappears. ________________ 8. Daughter cells form. ___________________ 9. Double-stranded chromosomes line up in the centre of the cell. ________________ 10. It makes up most of a cell’s life. _________________ Short Answer 11. In mitosis, how many cells form from the original cell? _________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 CLASS: The Cell Cycle and Cancer BLM 2-15 Goal • Use this page to help you learn about cancer, the uncontrolled growth of cells. What to Do Checkpoints in a bike race ensure that the athlete and the bike are in good condition to continue in the race. There are also checkpoints in the cell cycle. Predict the answer to questions below, then read pages 159–161 to check your predictions. Questions Before Reading After Reading What I Think What I Learned Why is it important that there be checkpoints in the cell cycle? What causes a cell to become cancerous? How does a cancer cell look compared to a normal cell? How might the cell cycle be related to cancer? Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 CLASS: Factors That Affect Development of Cancer BLM 2-16 Goal • Learn about risk factors for developing cancer. Factor Effect Alcohol • Linked to cancers of the mouth, larynx, throat, esophagus, and liver Food • Obesity increases the risk of many cancers. • Salt-cured, smoked, and nitrite-cured foods are linked to cancers of the stomach and esophagus. • Additives and preservatives are linked to some cancers. • High-fat diets may contribute to the development of certain cancers . Home • Exposure to materials made from manufactured fibres such as carpets, plastic, rayon, and insulation linked to cancer • Exposure to cleaners, paints, and other chemicals linked to cancer Radiation • X rays, the Sun, and radon in cigarettes linked to cancer Sunlight • Exposure to sunlight is considered a major cause of skin cancer. Tobacco • Responsible for about 30 percent of all cancer-related deaths • Smoking is responsible for most cases of lung cancer. • Cause of mouth and throat cancer Work • Exposure to chemicals such as chromate and asbestos increases risk. What to Do Choose and complete one of the following activities. 1. One of the biggest challenges in public health is preventing young people from starting smoking. Conduct a poll among students to determine whether or not they are aware of the health risks associated with smoking. Ask them to list any health risks they can think of. Keep track of how many risks each student can identify. Present your findings in chart form. 2. Find out what the Non-Smokers’ Rights Association has been doing to try to eliminate smoking. Present your findings in an oral report. 3. Work with a partner and use information from the chart to design a healthy lifestyle for youth. Present your findings in the form of a news bulletin. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 CLASS: Observing the Cell Cycle in Plant Cells BLM 2-17 Goal • Use this page to record your observations of onion root tip cell cycle stages for Conduct an Investigation 5-1C, Observing the Cell Cycle in Plant Cells. What to Do Using high power on your microscope, find an onion root tip cell at each of the following stages and draw the cell in the appropriate box. Label the chromosomes and spindle fibres. Prophase Metaphase Anaphase Telophase Cytokinesis Interphase Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-17 continued What to Do Collect the following data using the directions on pages 162 and 163 of your student book. Record the data collected in the chart below. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 CLASS: Examining Ideas about Cloning BLM 2-18 Goal • Use this page to help you examine ideas about cloning. What to Do Read the list of words, sentences, and phrases below, which all connect in some way to cloning. Cut out the phrases and organize the ideas to represent your understanding of these statements and how they fit together. Construct a graphic organizer to illustrate your answer. Techniques of cloning Saves species close to extinction A clone would have feelings and emotions identical to those of the donor A clone would be the same age as the donor Produces plants that produce high crop yields Reproductive cloning Produces an animal that has become extinct Produces a copy of yourself so that you will be immortal Produces another you so that there will be a supply of your organs in case any of your organs fail Possible applications of cloning Therapeutic cloning Produces organs for transplant Produces copies of your skin cells to treat burns Misconceptions about cloning Cloning Produces copies of Albert Einstein or other famous people Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 New Plants from Cuttings CLASS: BLM 2-19 Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 New Plants from Roots CLASS: BLM 2-20 Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 New Plants from Stems CLASS: BLM 2-21 Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 New Plants from Grafting CLASS: BLM 2-22 Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 Comparing Reproductive and Therapeutic Cloning CLASS: BLM 2-23 Goal • Use this page to compare the similarities and differences between reproductive and therapeutic cloning. What to Do After reading pages 176–178 in the student book, construct a Venn diagram to compare reproductive and therapeutic cloning. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 CLASS: Determining the Best Conditions for Yeast Reproduction BLM 2-24 Goal • Use this page to record your observations for Conduct an Investigation 5-2B, Determining the Best Conditions for Yeast Reproduction. What to Do Follow the directions on pages 179–181 in your student book to perform the experiment and record your data below. Part 1 Observing Budding in Yeast Draw your observations of the yeast under the microscope using high power in the circle at right. Part 2 Flask Observing the Effect of Nutrients Conditions A 0 g sucrose B 5 g sucrose C 30 g sucrose D 50 g sucrose Part 3 Flask Fermentation Observed Carbon Dioxide Produced (balloon circumference in cm) Observing the Effect of pH Conditions E 40°C + pH 3 F 40°C + pH 5 G 40°C + pH 7 H 40°C + pH 10 Fermentation Observed Carbon Dioxide Produced (balloon circumference in cm) Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 Chapter 5 Quiz CLASS: BLM 2-25 Goal • Check your understanding of Chapter 5. What to Do Circle the letter of the best answer. 1. The three stages of the cell cycle in order are A. interphase, cytokinesis, and mitosis B. interphase, replication and cytokinesis C. cytokinesis, replication, and interphase D. interphase, mitosis, and cytokinesis. 2. The purpose of DNA replication is to A. separate the DNA strands B. separate the contents of the cell’s nucleus C. pair new bases with bases on the original DNA D. make an identical copy of the DNA 3. Which of the following is the correct order of the stages of mitosis? A. telophase, anaphase, metaphase, prophase B. anaphase, metaphase, prophase, telophase C. anaphase, prophase, metaphase, telophase D. prophase, metaphase, anaphase, telophase 4. How does the cell cycle differ in plants and animals? A. In plants, the daughter cells are not identical to the parent. B. In plants, a cell plate forms between the daughter cells. C. In plants, there are no spindle fibres formed. D. In plants, the centrioles move to opposite poles. 5. Which of the following descriptions does not describe cancer cell growth? A. Cancer cell growth is highly controlled. B. Cancer cell has large abnormal nucleus. C. Cancer cells move to new locations. D. Cancer cells are unspecialized. 6. Which of the following organisms is not matched with its method of asexual reproduction? A. yeast, budding B. hydra, binary fission C. sea star, fragmentation D. bacteria, spores Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-25 continued 7. If one cell divided once every hour, how many cells would be produced after eight hours? A. 16 B. 32 C. 64 D. 256 8. Which of the following is a disadvantage of asexual reproduction? A. Offspring are genetic clones. B. Many offspring are produced. C. Energy is not required to find a mate. D. Large colonies are produced. 9. Which of the following is not a method of vegetative reproduction? A. forming bulbs B. forming sprouts C. forming runners D. forming spores 10. Which of the following are the correct steps in DNA replication? 1. Each side of the ladder is a template on which a new side forms. 2. Enzymes separate the DNA molecule. 3. New bases pair with bases on the original DNA strand. 4. The DNA molecule unwinds. A. 1, 2, 3, 4 B. 2, 4, 1, 3 C. 3, 2, 4, 1 D. 4, 2, 1, 3 Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-25 continued Match each Term on the left with the best Descriptor on the right. Each Descriptor may be used only once. Terms Descriptors _____ 11. prophase A. nuclear membrane forms around chromosomes _____ 12. telophase B. chromosomes form a single line at cell equator _____ 13. anaphase C. the two nuclei separate _____ 14. cytokinesis _____ 15. metaphase D. chromosomes attach to spindle fibres at their centromeres _____ 16. interphase E. DNA replicates F. sister chromatids move to opposite poles of the cell G. the chromosomes dissolve 17. What are three requirements which must be met before a cell continues through the cell cycle? _____________________________________________________________________________ _____________________________________________________________________________ _____________________________________________________________________________ 18. (a) How are binary fission and budding similar? _____________________________________________________________________________ _____________________________________________________________________________ (b) How are binary fission and budding different? _____________________________________________________________________________ _____________________________________________________________________________ 19. Explain the disadvantages of asexual reproduction. _____________________________________________________________________________ _____________________________________________________________________________ _____________________________________________________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 CLASS: Using DNA to Solve Crimes BLM 2-26 Goal • Use this page to learn how DNA can be used to solve crimes. What to Do Tree theft is a serious problem in British Columbia. Catching a tree thief is a difficult task. Forensic techniques are available to help solve these types of crimes. Read the information below. Then answer the questions that follow. The Crime Scene The red cedar was over 60 m high. It had stood for 650 years in the cool, moist coastal forest near Bella Coola. When it was a young sapling, it was shaded by the ancient trees around it. As it grew, its drooping branches provided winter food for moose, elk, and deer. Hundreds of generations of squirrels had dined on its cones. For centuries, bald eagles, chickadees, tree swallows, spotted owls, and woodpeckers nested in its branches. In winter, raccoons made dens in the cavities of its trunk. The tree was not harmed by insects because it produced pungent oils that made it resistant to pests. For hundreds of years, local Aboriginal people had used bark from the ancient tree to make clothing. The red cedar had narrowly escaped forest fires started by lightning many times through the centuries. Fire was its only enemy. The site where the cedar grew was in a natural area that was protected from forestry and development. One day, however, people with chainsaws arrived at its site. Within hours, the red cedar had been cut down and taken from the forest. What remained in the forest was a huge stump three meters in diameter and a large pile of sawdust. A forest ranger came upon the crime scene weeks later and reported the theft to the RCMP. When the officers arrived to investigate, they shook their heads sadly. The diameter of the red cedar trunk was the largest the officers had investigated yet. It had been weeks since the crime was committed, but there was still evidence remaining to be collected. The RCMP officers loaded the evidence in the van. They were determined to solve this case. Tree thieves steal an estimated $150 million dollars of timber each year in British Columbia. Giant ancient cedars are becoming increasingly rare. Old-growth red cedar is a prime target because it is valued for its resistance to decay. Red cedar is used for house siding, decking, and shingles, and the old growth wood is highly sought after by violin and cello makers. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-26 continued Questions 1. Imagine you are investigating this crime. Working with a partner, outline a description of the victim. Include the victim’s height, diameter, age, and location. Identify any other organisms of the forest that were affected by this crime and explain how they are affected. 2. What might be the motive for this crime? 3. List the steps or procedures that forensic specialists use to investigate any type of crime scene. 4. Review your list and determine what evidence might be available at this crime scene. 5. Describe how this evidence might be collected. 6. Predict what the thieves might do with the stolen tree. 7. Determine how the evidence collected may be used to catch the thieves. 8. Compare your list and techniques to those of other biodetectives in the class. What Did You Find Out? 1. (a) How did your forensic methods to solve this crime compare to other methods proposed by your classmates? _____________________________________________________________________________ _____________________________________________________________________________ (b) What could you add to your methods to improve them? _____________________________________________________________________________ _____________________________________________________________________________ 2. What were key pieces of evidence needed to solve this crime? _____________________________________________________________________________ _____________________________________________________________________________ 3. How could sawmills be made accountable in identifying the source of the wood that they process? _____________________________________________________________________________ _____________________________________________________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 How Variation Occurs in Meiosis CLASS: BLM 2-27 Goal • Review your understanding of how variation occurs in meiosis. What to Do 1. Complete the concept map to connect ideas on variation in meiosis. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 Gametes CLASS: BLM 2-28 Goal • Review your understanding of gametes. What to Do In the spaces provided, write the term from the list below that best completes the sentence. Terms may be used more than once. You will not need to use every term. body cells, chromosomes, crossing over, egg cells, gametes, meiosis, mitosis, sperm cells 1. Organisms produce ___________________________ through mitosis. 2. The main job of ________________________ is to join together to produce a new organism. 3. In humans, _________________________ have 46 chromosomes. 4. Gametes are the only cells that are not produced by ___________________________. 5. ________________________________ are the female gametes. 6. ________________________________ are the male gametes. 7. __________________________________ contain the instructions that tell a cell how to develop. In the space provided, answer the following question. 8. Describe the relationship between chromosome numbers in body cells and gametes. ______________________________________________________________________________ ______________________________________________________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 Key Events in Meiosis CLASS: BLM 2-29 Goal • Review the steps of meiosis. What to Do Use the diagram to answer the questions that follow. 1. Each chromosome doubles itself, forming two identical copies, called sister chromatids. (a) How many chromosomes are in diagram 1? ______ (b) How many chromatids ? _______ 2. The doubled chromosomes come together in matching pairs in diagram 2. Where do they line up? ___________________________________________________________________ 3. (a) The chromosomes separate in diagram 3. Where are they pulled? ___________________ (b) Are the chromosomes that have been pulled all the same or are they different? _________ 4. The first division of meiosis has occurred, and the cell has formed two new cells (diagram 4). What are the contents of these cells? ________________________________________________________ 5. In diagram 5, the chromosomes again line up along the centre of each new cell. How does this step differ from diagram 2? ___________________________________________________ 6. In diagram 6, the sister chromatids separate and move to opposite ends of the cell. How is this stage of meiosis very similar to mitosis? _________________________________________ 7. (a) The cells divide in diagram 7. How many new cells are formed by meiosis? ____________ (b) Compared to the parent cell, how many chromosomes does a new cell have? ___________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 5 CLASS: Compare the Events of Meiosis and Mitosis BLM 2-30 Goal • Use this page to compare the events of meiosis and mitosis. What to Do Study the diagrams of mitosis and meiosis in your student book. Use words and/or labelled drawings to compare the following events. Meiosis I Mitosis Prophase I Prophase (early and late) Metaphase I Metaphase Anaphase I Anaphase Telophase I Telophase Interkinesis Cytokinesis Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-30 continued Meiosis II Mitosis Prophase II Prophase (early and late) Metaphase II Metaphase Anaphase II Anaphase Telophase II Telophase Cytokinesis Cytokinesis Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 CLASS: Compare the Results of Meiosis and Mitosis BLM 2-31 Goal • Compare the results of mitosis and meiosis. What to Do Complete the chart and answer the questions that follow. Comparing Meiosis and Mitosis Meiosis Mitosis gamete Body cell 2. Number of chromosomes before cell begins to divide 4 4 3. Number of chromosome pairs in the original cell 2 2 1. Type of cell undergoing reproduction 4. Final number of chromosomes in each new cell at the end of division 2 4 5. Chromosome pairs in each new cell at end of division None 2 6. Compare the location and arrangement of chromosomes in the cell during metaphase I in meiosis and metaphase in mitosis. In mitosis, chromosomes are not paired, but they do line up along the cell centre. In meiosis, chromosomes first line up and then become arranged along the cell centre ______________________________________________________________________________ ______________________________________________________________________________ 7. Compare the location and arrangement of chromosomes in the cell during anaphase I in meiosis and anaphase in mitosis. The locations are the same, but in meiosis, in each pair of sister chromatids, the original and copy are still attached to each other ______________________________________________________________________________ ______________________________________________________________________________ 8. How do the end results of meiosis and mitosis differ? Mitosis produces 2 cells identical to the original one / Meiosis produces four cells, each with half the chromosomes of the original one ______________________________________________________________________________ ______________________________________________________________________________ 9. Predict what would happen if gametes were produced by mitosis rather than meiosis. The resulting organism would have twice the normal number of chromosomes ______________________________________________________________________________ ______________________________________________________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 Mitosis and Meiosis CLASS: BLM 2-32 Goal • Review your understanding of mitosis and meiosis. What to Do Match each of the following descriptions with the corresponding event depicted in the diagram below. Write the correct letter in each blank. _________ 1. Chromatids are still joined in meiosis, but not in mitosis. _________ 2. Chromatids separate. _________ 3. Chromosomes double in both mitosis and meiosis. _________ 4. Mitosis is complete, but another division is about to take place in meiosis. The chromosomes line up along the centre of the cell. _________ 5. In meiosis, the chromosomes separate but chromatids remain joined. In mitosis, chromatids separate. _________ 6. Chromosomes line up in pairs in meiosis but not in mitosis. _________ 7. End products of meiosis Short Answer 8. Use “haploid” and “diploid” to compare the end products of meiosis with the end products of mitosis. How do they differ? _____________________________________________________________________________ _____________________________________________________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 CLASS: BLM 2-33 Gamete Summary Goal • Summarize what you understand about gametes. What to Do 1. Place a check mark (9) to show which kind of cell has the trait listed in the first column. Trait Sperm Cell Has a tail Egg Cell Both Sperm Cells and Egg Cells ㅇ Has 23 chromosomes ㅇ Involved in fertilization Formed in testes ㅇ ㅇ ㅇ Contains cytoplasm Motile ㅇ ㅇ Produced by meiosis Formed in ovaries ㅇ Has a food reserve ㅇ ㅇ Forms a zygote 2. Describe how a zygote is produced. A zygote is produced by the union of sperm and egg ; the sperm fertilizes the egg ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 Several Types of Chromosome Mutations CLASS: BLM 2-34 Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 CLASS: Modelling How Variation Occurs in Meiosis BLM 2-35 Goal • Use this chart to help you complete Investigation 6-1D, Modelling How Variation Occurs in Meiosis. What to Do Use pencil crayons to draw the chromosomes before and after crossing over occurs. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 Cell Reproduction CLASS: BLM 2-36 Goal • Review your understanding of mitosis and meiosis. What to Do Read the statements given below. If the statement is true, write “T” on the line in front of the statement. If it is false, write “F” and rewrite the statement to make it true. ____ 1. Gametes have twice as many chromosomes as other cells. _________________________________________________________________________________ ____ 2. Zygotes are produced by the union of sperm and egg cells. _________________________________________________________________________________ ____ 3. Meiosis may form egg cells. _________________________________________________________________________________ ____ 4. Gametes are formed during mitosis. _________________________________________________________________________________ ____ 5. Only a diploid zygote can function as the offspring’s first body cell. _________________________________________________________________________________ ____ 6. Four new cells are formed from each parent cell in meiosis. _________________________________________________________________________________ ____ 7. There are two cell divisions during mitosis. _________________________________________________________________________________ ____ 8. Haploid refers to the gametes of a cell with only one set of chromosomes. _________________________________________________________________________________ ____ 9. If a cell with six chromosomes undergoes mitosis, each new cell will also have six chromosomes. _________________________________________________________________________________ _________________________________________________________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 Critical Periods of Embryonic and Fetal Development CLASS: BLM 2-37 Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 Chapter 6 Quiz CLASS: BLM 2-38 Goal • Check your understanding of Chapter 6. What to Do Circle the letter of the best answer. 1. Which of the following is the correct order in sexual reproduction? A. meiosis, gamete, fertilization, embryo B. gamete, meiosis, fertilization, embryo C. fertilization, meiosis, gamete, embryo D. gamete, fertilization, meiosis, embryo 2. Mitosis is similar to meiosis II because A. in both processes, the number of chromosomes is doubled B. in both processes, identical daughter cells are produced C. in both processes, sister chromatids separate and move to opposite poles D. in both processes, homologous chromosomes separate and move to opposite poles 3. Which of the following events occurs in mitosis only? A. produces genetically different cells B. produces haploid cells C. cells divide two times D. produces genetically identical cells 4. Gamete formation in males is different than in females because A. in males, meiosis begins before birth and stops until puberty B. in males, meiosis II occurs before meiosis I C. in males, there is equal distribution of cytoplasm into four cells D. in males, there is unequal distribution of cytoplasm into four cells 5. The difference between gene mutations and chromosomal mutations is that A. a single gene mutation can affect many genes in the chromosomes B. gene mutations are the result of mutagens such as radiation C. chromosomal mutations affect the sequence of the bases D. chromosomal mutations can affect many genes in the chromosomes 6. A mutation that would be inherited must occur in a A. skin cell B. egg cell C. muscle cell D. cancer cell Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-38 continued 7. Cow body cells have 60 chromosomes. How many chromosomes will be in a sperm cell following meiosis II? A. 30 B. 60 C. 120 D. 15 8. In the gastrula, cells in the mesoderm layer will become A. kidneys B. skin C. lungs D. liver 9. What is the main advantage of sexual reproduction? A. Very little energy is required to find a mate. B. Fewer offspring are produced. C. The embryo is protected from dehydration. D. The offspring are genetically different from the parents. 10. The procedure when a single sperm is injected into an egg cell is known as A GIFT B. ICSI C. AI D. IVF Match each Term on the left with the best Descriptor on the right. Each Descriptor may be used only once. Term ___ 11. prophase I ___ 12. telophase II ___ 13. anaphase I ___ 14. metaphase II ___ 15. anaphase II ___ 16. prophase II Descriptor A. the chromosomes form a single line at the equator B. sister chromatids move to opposite poles of the cell C. there is one chromosome of the homologous pair in each cell D. homologous chromosomes pair up and nonsister chromatids exchange genetic material E. a nuclear membrane forms around each set of chromosomes F. independent assortment of chromosome pairs occurs G. DNA replicates Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-38 continued 17. Explain how the events of sexual reproduction produce variation in a species. _____________________________________________________________________________ _____________________________________________________________________________ _____________________________________________________________________________ 18. Explain how sexual reproduction by internal fertilization provides advantages over external fertilization. _____________________________________________________________________________ _____________________________________________________________________________ _____________________________________________________________________________ 19. What are three advantages of assisted reproductive technologies? _____________________________________________________________________________ _____________________________________________________________________________ _____________________________________________________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 Unit 2 Test CLASS: BLM 2-39 Goal • Test your understanding of Unit 2, Reproduction. What to Do Circle the letter of the best answer. 1. A skin cell functions differently than a muscle cell because A. there are different genes in each cell B. there are different DNA molecules in each cell C. different proteins are made in each cell D. different genes are made in each cell 2. RNA is an important molecule in the cell because it A. carries information from one generation to the next B. carries information from the cell to the rest of the body C. carries information from the ribosome to the nucleus D. carries information from the nucleus to the cytoplasm 3. If one side of a DNA molecule had the bases ACGTTGACT, the order of the bases on the other side of the strand would be A. ACGTTGACT B. TGCAACTGA C. GTACCAGTC D. CGCAACTA 4. Which is not a use for gene therapy? A. to clone an organism B. to replace a mutated gene with a healthy gene C. to deliver healthy genes using inactive viruses to treat cystic fibrosis D. to alter the immune system 5. Which of the following is not a step in DNA replication? A. The DNA molecule unwinds. B. The steps of the DNA ladder break apart to form a template. C. The RNA is copied from the DNA molecule. D. The new side forms and A pairs with T and G pairs with C. 6. In the DNA sequence GACTGACTGACT, a mutation occurred and the piece of DNA then contained the letters GACTTGACTGACT. What type of mutation is this an example of? A. deletion B. addition C. substitution D. translocation Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-39 continued 7. People with Down syndrome have A. 47 chromosomes in their karyotype B. 45 chromosomes in their karyotype C. three copies of chromosome 18 D. one copy of chromosome 21 8. The embryonic stage where the embryo cells are arranged into a hollow ball is called a A. morula B. blastula C. gastrula D. fetus 9. Which event in prophase of mitosis is incorrect? A. The nucleolus disappears. B. Centromeres pull apart. C. Spindle fibres form. D. Individual chromosomes attach to spindle fibres. 10. Which of the following best describes the events of anaphase 1? A. Homologous chromosomes pair up at the equator. B. One chromosome from each homologous pair is at each pole of the cell. C. The centromere pulls apart, and the sister chromatids separate and are pulled to opposite poles by the spindle fibres. D. Homologous chromosomes attached to centromeres separate and are pulled to opposite poles by the spindle fibres. Match each Term on the left with the best Descriptor on the right. Each Descriptor may be used only once. Term ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ 11. gametes 12. mitosis 13. ectoderm 14. stem cells 15. zygote 16. meiosis 17. diploid 18. sexual reproduction 19. endoderm 20. independent assortment Descriptor A. two sets of chromosomes B. formed from the process of fertilization C. produces genetically different offspring D. these cells will form the lungs and liver E. specialized cells needed for reproduction F. the process where duplicated chromosomes divide in two G. produces variation H. these cells will form the brain I. have the potential to become any type of cell J. process that produces gametes K. only one parent is required to produce offspring Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-39 continued 21. How does the nucleus control the functions of life? ____________________________________________________________________________________________ ____________________________________________________________________________________________ ____________________________________________________________________________________________ 22. Explain how the gene message creates a protein in the cell. ____________________________________________________________________________________________ ____________________________________________________________________________________________ ____________________________________________________________________________________________ 23. Why is interphase important for the cell and cell cycle? ____________________________________________________________________________________________ ____________________________________________________________________________________________ ____________________________________________________________________________________________ 24. (a) List three types of asexual reproduction. __________________________________________________________________________ __________________________________________________________________________ __________________________________________________________________________ (b) Provide an example of each type. __________________________________________________________________________ __________________________________________________________________________ __________________________________________________________________________ 26. (a) What are mutations? __________________________________________________________________________ __________________________________________________________________________ (b) How are mutations caused? __________________________________________________________________________ __________________________________________________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-39 continued 27. Why may human-assisted plant and animal cloning methods be useful in the future? ____________________________________________________________________________________________ ____________________________________________________________________________________________ ____________________________________________________________________________________________ 28. Describe how the process of fertilization takes place within a flower. ____________________________________________________________________________________________ ____________________________________________________________________________________________ ____________________________________________________________________________________________ 29. What main events occur in fetal development within the first three months following fertilization? ____________________________________________________________________________________________ ____________________________________________________________________________________________ ____________________________________________________________________________________________ 30. What are three societal issues involving reproductive technology? ____________________________________________________________________________________________ ____________________________________________________________________________________________ ____________________________________________________________________________________________ Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 Making a Decision for Genetown Stakeholder List CLASS: BLM 2-40 Goal • Use this page to determine your stakeholder position for the Unit 2 Project. What to Do Choose one of the following roles to represent. 1. A patient who had unsuccessful stem cell treatment 2. An entrepreneur who wants to open a national umbilical cord bank and is willing to help fund this project 3. A 40-year-old person afflicted with Parkinson’s disease 4. A couple who have a child afflicted with leukemia. They have stored embryos at the in vitro clinic and they are hopeful that stem cell research will cure their afflicted child. 5. The child and caregiver of parents who both have Alzheimer’s disease 6. A representative of a drug company that wants to use stem cells to test drugs 7. A high school student who became a paraplegic following a skiing accident 8. A person who has heart cell damage following a heart attack 9. A politician who is looking out for public safety over economic gains 10. A member of the National Bioethics Society who questions if everyone will have equal access to stem cell treatment 11. A Right to Life advocate who believes that an embryo should receive the same respect before birth as it would if already born 12. A member of a couple who spent thousands of dollars for successful in vitro fertilization treatments. They now have two children but they have a lot of debts and would be willing to sell their remaining frozen embryos. 13. A local resident who is afraid that the research company is going to manufacture an army of human clones 14. A somatic cell nuclear transfer specialist 15. A doctor from the provincial children’s hospital 16. A concerned citizen who believes that this overseas company will obtain embryos illegally 17. A religious leader Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CLASS: BLM 2-40 continued 18. A researcher from the nearby university college who is studying the development of humans from fertilized egg to adult 19. The director of the in vitro fertilization clinic in the city 20. The largest financial investor in Stem Cells Now 21. A director of the biotechnology department of the university college who hopes to attract world leaders in stem cell research to the province and to Genetown 22. A Genetown taxpayer 23. A local mall owner 24. The mayor who will conduct the meeting 25. A town council member who will listen to the viewpoints, then meet to vote and decide on the future of Stem Cells Now in Genetown 26. A town council member who will listen to the viewpoints, then meet to vote and decide on the future of Stem Cells Now in Genetown 27. A town council member who will listen to the viewpoints, then meet to vote and decide on the future of Stem Cells Now in Genetown 28. A patient who had a successful stem cell treatment 29. An unemployed but skilled worker who could work for Stem Cells Now 30. A construction contractor who would build the Stem Cells Now building Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 CLASS: Presentation Organizer BLM 2-41 Goal • Prepare for a formal presentation to a committee. What to Do Use this page to organize your arguments. My role _________________________________________________________________________ Props I will use ___________________________________________________________________ Arguments I will present My arguments Support for my arguments Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 CLASS: BLM 2-42 Debate Procedures Goal • Review and use the process of a formal debate. Think About It A formal debate has an orderly step-by-step procedure that is followed by people who take opposing or contradictory views of issues presented as resolutions. There can be four speakers, two for the resolution and two against. A debate chair introduces the resolution, rules, speakers, and the order in which the speakers present their views. The debate chair also announces the winner after taking a vote to determine which side supported its points better. Speaker Time Job Speaker #1 for the resolution 3 min • clarifies the resolution or issue • supports the resolution • often introduces a plan showing how the resolution could be implemented Speaker #1 against the resolution 3 min • challenges the definitions, points, and evidence given by Speaker #1 for the resolution • offers points against the resolution • sums up why Speaker #1 was wrong or misguided and why the negative position is preferred Speaker #2 for the resolution 3 min • counters the points given by Speaker #1 against the resolution • supports the good points made by Speaker #1 for the resolution • makes any new points Speaker #2 against the resolution 3 min • makes any new points • counters specific points supporting the resolution • clarifies the position against the resolution BREAK FOR UP TO THREE MINUTES Speaker against 2 min the resolution • points out where speakers for the resolution have failed to prove their points • sums up the points made by the team against the resolution Speaker for the resolution • points out why the resolution must succeed • makes a final review of the position for the resolution 2 min Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. DATE: NAME: CHAPTER 6 Unit 2 Review Concept Map CLASS: BLM 2-43 Goal • Use this concept map to complete question 1, Unit 2 Review, page 238 of BC Science 9. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. UNIT 2 Unit 2 BLM Answers BLM 2-44 BLM 2-5, Cell Organelles Cell Part Function Cytoplasm Gel-like material inside cells Nucleus Directs cell activities Endoplasmic reticulum Folded membrane that transports materials inside the cell Ribosome Manufactures substances important for cell functions Mitochondrion Releases energy in the cell Chromatin Mass of dispersed genetic material Chloroplast Contains chlorophyll, the pigment for photosynthesis Vacuole Stores water, food, and waste products Golgi body Stacks of sacs that package and transport proteins Lysosome Digests wastes BLM 2-7, Extracting DNA from Strawberries 1. plastic bag 2. (a) 5 mL dish soap (b) 2.5 mL table salt (c) 25 mL tap water 3. 5 min 4. one-half 5. ice cold, graduated cylinder 6. layer, three-quarters BLM 2-8, Making Predictions about Mutations Term Positive mutation Before Reading What I Think the Term Means/Example Students’ answers will vary. After Reading What the Term Means/Example A change in the DNA that produces a change that benefits the organism Example: A few people are resistant to HIV infection. Negative mutation Students’ answers will vary. A change in the DNA that produces a change that harms the organism Example: Substitution of base A for T causes sickle cell anemia. Neutral mutation Students’ answers will vary. A change in the DNA that produces a change that neither benefits nor harms the organism Example: Spirit Bear, since it has no natural predators Mutagen Students’ answers will vary. Substance that causes a mutation, such as asbestos, cigarette smoke, X rays Gene therapy Students’ answers will vary. Treatment used to correct gene mutations, such as treatment for cystic fibrosis Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. BLM 2-44 continued BLM 2-9, Chapter 4 Quiz 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. C D B A D B A D C B D C F E A B The nucleus contains DNA, which carries the code to make and specific proteins, such as enzymes and hormones that perform specific functions in the cell. 18. Three types of gene mutations are deletions, additions, and substitutions. 19. The chart should connect the terms in a similar way to the example below: DNA codes for a protein. The RNA message for a protein is copied from the DNA. RNA leaves through a nuclear pore. RNA goes to the ribosomes, and the protein is made. The protein enters the endoplasmic reticulum. A vesicle forms off the endoplasmic reticulum and goes to the Golgi body. The Golgi body repackages the protein for export out of the cell. BLM 2-11, Stages of the Cell Cycle Name of Cell Cycle Stage Cell Activities Longest stage of cell cycle Interphase Nucleus Activities DNA inside nucleus is replicated Cell carrying on its functions Cell doubles everything in cytoplasm Growth and Preparation Cell increases in size Cell makes proteins Organelles duplicate Replication DNA inside nucleus is replicated Continued Growth and Preparation Cell gets larger Cell makes proteins Organelles duplicate Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. BLM 2-44 continued Mitosis Shortest stage Contents of cell nucleus divides Early prophase Spindle fibres begin to form and centrioles appear in animal cells X-shaped chromosomes become visible Nucleolus disappears Nuclear membrane begins to break down Late prophase Spindle fibres complete forming Chromosomes attach to spindle fibres Nucleus no longer visible Metaphase Spindle fibres pull chromosomes into a single line at equator Nucleus no longer visible Anaphase Sister chromatids separate and move to opposite poles Nucleus no longer visible Telophase One complete set of chromosomes now at each pole of the cell Spindle fibres disappear Cytokinesis Two nuclei separated into two daughter cells Cell membrane pinches together to divide the cell’s cytoplasm and organelles Nucleus now bound by membrane BLM 2-12, The Cell Cycle 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. D C A A E C B D E Structures Present Interphase Prophase Metaphase Anaphase Telophase Nucleus 9 9 Nucleolus 9 9 Nuclear membrane 9 9 Chromatin 9 9 9 9 Chromosomes 9 9 9 9 Spindle fibres 9 9 9 9 11. Replicated DNA separates into two identical sets of DNA, one for each new cell’s nucleus. BLM 2-13, Steps of Mitosis Description answers will vary. Suggested descriptions are given below. Phase 1: Prophase Nucleus and nuclear membrane disappear. Spindle fibres begin to form. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. BLM 2-44 continued Phase 2: Metaphase Spindle fibres pull double-stranded chromosomes across the middle of the cell. Phase 3: Anaphase Spindle fibres pull centromeres apart. One of each of the replicated strands moves to opposite poles of the cell. Phase 4: Telophase One set of chromosomes is now at each pole of the cell. Spindle fibres disappear. A nuclear membrane re-forms around each set of chromosomes. BLM 2-14, Cell Growth and Division 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. anaphase prophase telophase anaphase interphase cell division prophase cell division metaphase interphase two cells BLM 2-15, The Cell Cycle and Cancer Questions What I Think What I Learned Why is it important that there be checkpoints in the cell cycle? Students’ answers will vary. The cell will die if it divides without enough nutrients, or with too many DNA errors, or if the DNA did not replicate correctly. What causes a cell to become cancerous? Students’ answers will vary. A mutation can occur in a checkpoint protein, and then cell cycle control will be lost. How does a cancerous cell look compared to a normal cell? Students’ answers will vary. Cells grow in multilayers. The cells have large abnormal nuclei because the nuclei may be full of undivided chromosomes. How might the cell cycle be related to cancer ? Students’ answers will vary. With the loss of cell cycle checkpoints, the cell could undergo uncontrolled cell division. BLM 2-23, Comparing Reproductive and Therapeutic Cloning Reproductive cloning: produces a clone of an existing organism; the purpose is to clone an individual with desirable qualities Both: types of human-assisted animal cloning; involve the transfer of a nucleus of one cell into enucleated egg cell Therapeutic cloning: produces a clone of an organ or tissue; the purpose is to correct health problems BLM 2-25, Chapter 5 Quiz 1. D 2. D Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. BLM 2-44 continued 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. D B A B D A D D D A F C B E Before a cell can continue through the cell cycle there must be enough nutrients to support cell growth, the DNA must be replicated, and the DNA should not be damaged. 18. (a) Binary fission and budding are both methods of asexual reproduction. (b) Differences are that binary fission occurs in unicellular organisms and budding can occur in both unicellular and multicellular organisms. Also, in binary fission one parent cell divides once into two same-sized daughter cells, whereas in budding there may be repeated cell divisions and an unequal-size outgrowth forms off the parent. 19. The main disadvantage of asexual reproduction is that the offspring are genetic clones. If the conditions change or a disease appears it could wipe out the whole population. BLM 2-26, Using DNA to Solve Crimes 1. Students’ answers may vary depending on their responses and those of other students. 2. The key pieces of evidence could have been materials left behind by the thieves that contained fingerprints or DNA, including tools, cigarette butts, and tire tracks. The tree stump leaves the tree ring pattern which could be matched to the stolen log; however, thieves are cutting a piece off the stump so this type of match is not simple. However, sawdust from the tree stump could be matched for DNA with sawdust from cut wood brought to a nearby sawmill. 3. A small sample from each log could be saved, and an inventory of the source of each log could be kept. BLM 2-27, How Variation Occurs in Meiosis 1. 2. 3. 4. 5. 6. meiosis I meiosis II homologous chromosomes sister chromatids crossing over, non-sister homologous chromosomes BLM 2-28, Gametes 1. 2. 3. 4. 5. 6. 7. 8. body cells gametes body cells mitosis egg cells sperm cells chromosomes Gametes have half the number of chromosomes as body cells. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. BLM 2-44 continued BLM 2-29, Key Events in Meiosis 1. (a) 4 chromosomes (b) 8 chromatids 2. Across the centre of the cell 3. (a) To opposite ends of the cell (b) Different 4. Each cell has one chromosome from each pair. Each chromosome is composed of sister chromatids 5. Chromosomes are not paired. 6. Sister chromatids separate as they do in mitosis. 7. (a) 4 new cells (b) Half the number of chromosomes BLM 2-30, Compare the Events of Meiosis and Mitosis Key • • • • • Meiosis I Mitosis Prophase I Prophase (early and late) nucleolus disappears nuclear membrane disappears spindle fibres form homologous chromosomes pair up and each attach to spindle fibres non-sister chromatids exchange genetic material (crossing over) • • • • Metaphase I • homologous chromosomes pair up at the equator nucleolus disappears nuclear membrane disappears spindle fibres form individual chromosomes attach to spindle fibres Metaphase • chromosomes form a single line at the equator Anaphase I Anaphase • spindle fibres contract and shorten • spindle fibres contract and shorten • homologous chromosomes attached to centromeres • the centromere pulls apart, and the sister separate and are pulled to opposite poles by the spindle fibres chromatids separate and are pulled to opposite poles by the spindle fibres Telophase I • one chromosome from each homologous pair is at • • • each pole of the cell the spindle fibres disappear the nucleolus appears within each nucleus the nuclear membrane forms Telophase • one complete set of chromosomes is now at each • • • Interkinesis • cell divides in two (not genetically identical to • • parent cell) cell will grow and make proteins like interphase in mitosis no replication of DNA in this stage pole of the cell the spindle fibres disappear the nucleolus appears within each nucleus the nuclear membrane forms Cytokinesis • cell divides in two (genetically identical to parent • • cell) cell will grow and make proteins like interphase in mitosis DNA will replicate later in interphase Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. BLM 2-44 continued • • • • Meiosis II Mitosis Prophase II Prophase (early and late) nucleolus disappears nuclear membrane disappears spindle fibres form individual chromosomes attach to spindle fibres • • • • nucleolus disappears nuclear membrane disappears spindle fibres form individual chromosomes attach to spindle fibres Metaphase II • X-shaped chromosomes form a single line at the equator Metaphase • X-shaped chromosomes form a single line at the equator Anaphase II Anaphase • spindle fibres contract and shorten • spindle fibres contract and shorten • the centromere pulls apart and the sister chromatids • the centromere pulls apart, and the sister separate and are pulled to opposite poles by the spindle chromatids separate and are pulled to opposite poles by the spindle Telophase II • half of a complete set of chromosomes is now at • • • each pole of the cell (one chromosome for each pair) the spindle fibres disappear the nucleolus appears within each nucleus the nuclear membrane forms Telophase • one complete set of chromosomes is now at each pole of the cell • the spindle fibres disappear • the nucleolus appears within each nucleus • the nuclear membrane forms Cytokinesis • cell divides in two (total four daughter cells not • genetically identical to parent) cell will grow and make proteins like interphase in mitosis Cytokinesis • cell divides in two (genetically identical to parent) • cell will grow and make proteins like interphase in mitosis BLM 2-31, Compare the Results of Meiosis and Mitosis Comparing Mitosis and Meiosis Meiosis Mitosis 1. Type of cell undergoing reproduction gamete body cell 2. Number of chromosomes before cell begins to divide 4 4 3. Number of chromosome pairs in original cell 2 2 4. Final number of chromosomes in each new cell at the end of division 2 5. Chromosome pairs in each new cell at end of division none 4 2 6. In mitosis, chromosomes are not paired, but they do line up along the cell centre. In meiosis, chromosomes first line up and then become arranged along the cell centre. 7. The locations are the same, but in meiosis, in each pair of sister chromatids, the original and copy are still attached to each other. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. BLM 2-44 continued 8. Mitosis produces two cells identical to the original one. Meiosis produces four cells, each with half the chromosomes of the original one. 9. The resulting organism would have twice the normal number of chromosomes. BLM 2-32, Mitosis and Meiosis 1. 2. 3. 4. 5. 6. 7. 8. D F A E C B G Student answers should include the following points. • Mitosis produces diploid cells, or body cells. • Meiosis produces haploid cells, or gametes. BLM 2-33, Gamete Summary 1. Trait Has a tail Sperm Cell Egg Cell Both Sperm Cells and Egg Cells 9 Has 23 chromosomes 9 Involved in fertilization 9 Formed in testes 9 9 Contains cytoplasm 9 Motile 9 Produced by meiosis Formed in ovaries 9 Has a food reserve 9 Forms a zygote 9 2. A zygote is produced by the union of sperm and egg; the sperm fertilizes the egg. BLM 2-36, Cell Reproduction 1. 2. 3. 4. 5. 6. 7. 8. 9. False. Gametes have half as many chromosomes as body cells. T T False. Gametes are formed during meiosis. T T False. There is one cell division during mitosis. False. During sperm cell production, four haploid sperm cells are produced. T Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. BLM 2-44 continued BLM 2-38, Chapter 6 Quiz 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. A C D C D B A A D B D E F A B C Variation is produced through independent assortment and crossing over in meiosis and the meeting of egg and sperm in fertilization. 18. Sexual reproduction by internal fertilization provides advantages since there is more protection for embryos and more parental care of offspring, and offspring are genetically different. 19. Answers should include: Some infertile couples are able to have a child. Couples can select embryos to exclude embryos with genetic defects. Parents trying to help cure a sick child can screen and select embryos for tissue matches. Extra embryos can be made available for stem cell research. BLM 2-39, Unit 2 Test 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. C D B A C B A B B D E F H I B J A C D G The nucleus contains the genes that store the information to make proteins, and proteins have many different functions within the cell such as to function as enzymes and hormones. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher. BLM 2-44 continued 22. The gene message creates a protein in the cell when the DNA is copied into RNA message. Then RNA leaves the nucleus through the nuclear pores in the membrane and RNA travels to the ribosome, where proteins are made. If proteins are to be shipped out of the cell, proteins enter the endoplasmic reticulum for transport. Vesicles form off the endoplasmic reticulum and travel to the Golgi body for repackaging before they leave the cell. 23. Interphase is important for the cell and cell cycle because this is when DNA is replicated. New organelles and chemicals are made in preparation for cell division. 24. Types of asexual reproduction are binary fission seen in bacteria or amoebas, budding seen in sponges or yeast, fragmentation seen in algae or sea stars, and spore formation seen in ferns and mosses. 25 Differences between mitosis and meiosis are: two daughter cells result from mitosis, four daughter cell from meiosis; the chromosome number is diploid or 2n following mitosis and is haploid or n following meiosis, the genetic information is the same in the daughter cells following mitosis, the genetic information is different in daughter cells following meiosis 26. Mutations are errors in the DNA caused by errors when the DNA replicates or caused by environmental mutagens such as X rays and chemicals. They can be errors in the bases within a gene or can be large chromosomal errors where whole pieces of chromosomes are lost, duplicated, or moved to another chromosome. 27. Human-assisted plant and animal cloning methods will be useful in the future to produce a greater food supply with pest-and drought-resistant crops, to grow organs for transplant, and to help maintain endangered species. 28. A flower is fertilized when the pollen, the male gamete, lands on the stigma of the flower and a pollen tube forms which delivers the sperm to the ovule or ovary which contains the egg and where fertilization takes place. 29. The main events in fetal development that occur within the first three months following fertilization are the formation of the brain and spinal cord; fingers appear; and eyes, kidneys, lung, liver, and muscles develop. 30. Answers may vary, but may include: that they may cause a slightly higher number of birth defects: what to do with leftover embryos; the issue of inequity, since some couples cannot pay for the procedure; and who the parents are. Copyright © 2007, McGraw-Hill Ryerson Limited, a subsidiary of the McGraw-Hill Companies. All rights reserved. This page may be reproduced for classroom use by the purchaser of this book without the written permission of the publisher.