L Labor and Delivery ▶Birth Process Lactating ▶Breastfeeding Ladd-Franklin, Christine KELLI VAUGHN-BLOUNT York University, Toronto, Canada Life Dates (1847–1930) Introduction Christine Ladd-Franklin, American psychologist and logician, was best known in psychology for her theory of color vision and as a strong proponent for women’s equality within psychological science and academia. Educational Information Christine Ladd-Franklin, like many of her psychological female cohort, found the road to higher education to be a rocky one. Ladd-Franklin began her collegiate career at Vassar College. However, unlike many at the time, she did not come with extensive financial resources. She entered Vassar in the fall of 1866 but was only able to complete one year before financial problems forced her to withdraw. After a year of teaching, and with some assistance from an aunt, Ladd-Franklin returned to Vassar in 1868 and completed her A.B. in 1869. It would be some years, though not unproductive ones, before Christine LaddFranklin would continue her formal education. Between 1869 and 1876 she unofficially continued her education by attending courses as a non-admitted student at Washington College, Jefferson College, and Harvard [10]. Her studies at Washington and Jefferson focused primarily on mathematics. Her Harvard studies are still controversial; although, it is agreed that she spent at least one summer there pursuing botany studies. It was also during this period that she was teaching science and mathematics in girls’ high schools [8, 9]. In 1876, aware of the potential detriment of her sex, Ladd-Franklin wrote to the world-renowned mathematician James J. Sylvester at the newly formed Johns Hopkins University to inquire if her sex might in fact be a detriment to her admission [7]. Receiving Sylvester’s support, and that of the newly developed fellowship program, she submitted her application for graduate studies to the university. The application was submitted under the name C. Ladd (her maiden name) with impeccable credentials. She was officially accepted. That was until the trustees’ of the university discovered that C stood for Christine at which point Sylvester had to intervene on her behalf. Ladd-Franklin was finally admitted as a full time student, with special provisions, and three years of support from the fellowship but would not be formally recognized as equal to her peers for many years. While attending Hopkins, Christine Ladd-Franklin studied mathematics under Sylvester and symbolic logic under physicist Charles S. Pierce. She was the first American woman to formally receive graduate instruction in both [4, 8]. Like Mary Whiton Calkins at Harvard and Lillien Jane Martin, fellow Vassar alum, at Göttingen, Christine Ladd-Franklin completed all of the requirements for the Ph.D. at Johns Hopkins in 1882. She was however denied the degree, based solely on her sex, until 1926. Ladd-Franklin was seventy eight years old when she finally received her doctorate but she was still the one of the three pioneers mentioned above to do so. To date neither Harvard nor Göttingen has officially recognized Calkins or Martins degrees. Lillien Martin was awarded an honorary doctorate from the University of Bonn in 1910 allowing her to be officially referred to as doctor in her life-time. Mary Whiton Calkins, however, was offered only an alternative degree from Radcliffe in 1903 (Harvard’s women’s college during that period), which she refused on the grounds that she had attended Harvard and not Radcliffe. Sam Goldstein & Jack A. Naglieri (eds.), Encyclopedia of Child Behavior and Development, DOI 10.1007/978-0-387-79061-9, # Springer Science+Business Media LLC 2011 862 L Ladd-Franklin, Christine Christine Ladd-Franklin and Lillien Martin also shared one other similarity in their pursuit of higher education, G. E. Müller. Ladd-Franklin was the first female student and first American student of Georg Elias Müller at Göttingen in 1891 [3]. However, she spent only one year at the university. Lillien Martin followed in 1894 and would become the first woman and only American student to pursue a full five years of study under Müller at Göttingen. In later years, Ladd-Franklin would further her studies in color vision at the University of Berlin under Herman Von Helmholtz while Martin would go on to study mental imagery under Oswald Külpe at the University of Bonn. Accomplishments Christine Ladd to her detriment married fellow student and mathematician Fabian Franklin upon completion of her studies. Her marriage is important in that it not only exemplifies her feminist leanings, with the use of a hyphenated name, but also because the choice to marry would forever hinder her career. Christine Ladd-Franklin taught logic, mathematics, and psychological science throughout her career. In the early 1900s she primarily taught courses in logic and mathematics at Johns Hopkins. The bulk of her career, from 1915 until her death, would however be focused on psychology and philosophy at Columbia University. Due to her marital status, Columbia never provided her with a full professorship contract. A professional slight that was common to married women of the early twentieth century [7–10]. Christine Ladd-Franklin began publishing early. Her first recorded works on mathematics were published during her undergraduate years at Vassar. Between 1873 and 1871 she published mathematical formulas in the London Educational Times, The Analyst: A journal of Pure and Applied Mathematics, and the American Journal of Mathematics. It has been noted by historians that Ladd-Franklin’s 1877 publication in The Analyst is the first by a woman to appear in a mathematics journal [4, 8]. She is also considered a pioneer in the study of symbolic logic with her dissertation, The Algebra of Logic, appearing in the now seminal 1883 work edited by Pierce titled Studies in Logic by Members of the Johns Hopkins University. Philosophy historians have noted that Christine Ladd-Franklin reduced syllogism to a single formula and developed the primary principle for a recognized validation of forms of syllogisms [7]. LaddFranklins earliest foray into psychology through symbolic logic be seen in the 1889 edition of the American Journal of Psychology. Her influence on study of logic continues and has been widely recorded (See [12]). Contributions to Psychology It was in Germany that Ladd-Franklins earlier studies in botany, biology, and logic began to come together under a psychological umbrella of color vision. Her exposure to the two prominent color theories of the time: Helmholtz (later Young-Helmholtz) and Ewald Hering would alter the course of her already promising career. Christine Ladd-Franklin developed her own cumulative theory of color vision proposing that rather than the now classic, three or four, static color perception framework (e.g., Helmholtz or Hering) that a process existed whereby the ability to perceive color combinations evolved over time. The earliest version of her theory on color sensation was presented at the Second International Congress of Psychology in 1892 and published in the German Journal Zeitschrift fur Psychologie that same year. The American introduction to Ladd-Franklin’s theory, in a formal publication, appeared in Science in 1893. The bulk of the theory can be reviewed in Christine Ladd-Franklin’s book Colour and Colour Theories, which included many of her publishing’s on the topics [6]. This original text offers several colored images providing accessible visual summations of the theory. Ladd-Franklin’s theory included the only evolutionary postulate for the recognition of color sense perception with increased differentiation of photochemical receptors during that time [13]. Many considered her theory to be superior to both Helmholtz and Hering (See [2, 11]). Yet, the former continue to be cited in psychologies introductory texts while Ladd-Franklins is omitted. Ladd-Franklin published approximately 400 articles and books in mathematics, logic, and psychology in her life-time but is often remembered for the strength of her feminist ideologies rather than the insightfulness of her research. She was not known to let a sexist slight pass her by. She was one of the first two women, the other being Calkins, to be elected to the American Psychological Association, in 1893, but her tendency to buck the patriarchy within the discipline omitted her inclusion on prominent committees. She also often published on issues of equality for women within the academy. In 1903, Christine Ladd-Franklin had been listed in Catell’s Men of Science volume and was one of only three women psychologists starred that year, indicating eminence in the field. The most prominent of her publishing’s on women appeared the following year with her 1904 paper on Endowed Professorships for Women [5]. Ladd-Franklin’s battle of wills with Edward Titchner regarding the Society of Experimentalists is an often-cited example of her refusal to recognize female psychological scientists as anything other than equals. Titchner’s refusal Language Acquisition to admit women to the Experimentalists meeting is well recorded – as is Ladd-Franklin’s constant letters to him debating the decision. Margaret Floy Washburn and June Etta Downey were the first women officially admitted to the society, after Titchners death, but Christine LaddFranklin was the first to attend the meetings. Ludy Benjamin [1] has noted that at the 1914 meeting in New York, where Ladd-Franklin resided, she attended one session of the meeting. Titchner noted in a letter to Robert Yerkes that Ladd-Franklin had threatened some manner of a scene at the event and possible public protests in print. She had warned Titchner prior to the meeting that action was forthcoming and kept her word. Christine Ladd-Franklin’s contributions to the history of women in psychology finally began to be recognized in the 1980s. The height of which culminated in the Association of Women in Psychology’s (AWP) Christine Ladd Franklin Award in 1992. The award is given to the member with the most significant contribution to the AWP. The organization provides this description for the award “in honor of Christine Ladd-Franklin. . . an early scientist whose career provided a painful example of the way institutional sexism operated to exclude women from careers in psychology and the sciences.” It could also be added that she also showed what the women in nineteenth and early twentieth century managed to accomplish in spite of it. References 1. Benjamin, L. T. (2006). A history of psychology in letters (2nd ed.). Malden, MA: Blackwell. 2. Cadwallader, T. C., & Cadwallader, J. V. (1990). Christine Ladd-Franklin. In A. O’Connell & N. Felipe Russo (Eds.), Women in psychology: A biobibliographic sourcebook. Westport, CT: Greenwood Press. 3. Haupt, E. J. (1995). G. E. Müller: The Shaper of experimental psychology. Paper presented at the 1995 meeting of the American Psychological Association. http://www.chss.montclair.edu/psychology/ haupt/shaper2a.html. Retrieved 20 October 2005. 4. Jacob, K. (1976). How Johns Hopkins protected women from the rougher influences. Newsletter of the Association for Women in Mathematics, 7(4), 2–4. 5. Ladd-Franklin, C. (1904). Endowed professorships for women. Publications of the Association of Collegiate Alumnae, 3(9), 53–61. http:// psychclassics.yorku.ca/Ladd-Franklin/professorships.htm. Retrieved November 15 2008. 6. Ladd-Franklin, C. (1929). Colour and colour theories. New York, NY: Harcourt, Brace & Co. 7. Parshall, K. H., & Rowe, D. E. (1997). The emergence of the American mathematical research community, 1876–1900: J. J. Sylvester, Felix Klein, and E. H. Moore. Providence, RI: American Mathematical Society. 8. Rossiter, M. W. (1982). Women scientists in America: Struggles and strategies to 1940. Baltimore: Johns Hopkins University Press. 9. Scarborough, E., & Furumoto, L. (1987). Untold lives: The first generation of American women psychologists. New York: Columbia University Press. L 863 10. Stevens, G., & Gardner, S. (1982). The women of psychology (Vol. 1): Pioneers and innovators. Cambridge, MA: Schenkman. 11. Stevens, G., & Gardner, S. (1982). The women of psychology. Cambridge, MA: Schenkman. 12. Waithe, M. E. (Ed.). (1987). A history of women philosophers (Vol. 3): Modern women philosophers 1600–1900. Boston, MA: Springer. 13. Woodworth, R. S. (1930). Review of colour and colour theories. Psychological Bulletin, 27(2), 130–132. Language ▶Verbal Skills Language Acquisition AMY BURGER, IVY CHONG Florida Institute of Technology, Melbourne, FL, USA L Synonyms First language acquisition; Language learning; Native language acquisition Definition Language acquisition refers to the processes by which humans learn their native language(s) as children. Description For typical children, the foundations for language acquisition are laid before birth when the developing fetus is exposed to adult speech sounds. After birth, infants show signs of attending to speech and show a preference for their caretakers’ speech sounds [1]. As an infant matures, he or she will begin experimenting with vocalizations and various forms of babbling (Babbling consists of strings of random sounds composed of vowel-consonant or consonant-vowel combinations. Babbling is likely essential for speech development [1].) will begin around the age of 4 months. Between 7 and 12 months, an infant will begin to look at an object when its name is spoken and show other signs of word recognition [1]. Between the ages of 8 and 12 months, the infant begins to imitate the speech and communicative gestures of adults and older children: the emergence of echolalia (Echolalia is defined as the immediate imitation of another speaker’s speech [1].) is considered an important part of speech development. The child’s use of his or her first adult word will begin around 864 L Language Acquisition 12 months of age. The use of two-word sentences will begin around 18 months, and by the age of 24 months, a typical child will have a vocabulary of 200–300 words and will be able to form short sentences. Parents and caretakers often respond to their child’s developing language with a speech style known as motherese or parentese (Motherese, also known as parentese or baby-talk, is the style of speaking to young children and infants which typically involves slower speech, sentences that are shorter and simplified, and exaggerated pitch changes and stress patterns [1].). The shorter length of utterances typical of motherese may help to improve some types of language skills in young children [1]. After age 2, the child’s language acquisition increases rapidly. The vast majority of children will achieve basic competency in their language by age 5 [2]. Around age 6, typical children will begin to use all parts of speech, and sentences will become more complex. Between the ages of 8 and 12, children gain the ability to verbalize problems and ideas, including abstract concepts. The breadth of vocabulary and use of subtle, complex, and creative language will increase during adolescence and continue to develop throughout the lifespan [1]. Theories of Language Acquisition There are numerous theories of language acquisition. Three major theories of language acquisition are the behavioral theory, sociolinguistic theory, and the psycholinguistic or nativist model. The behavioral theory of language acquisition, developed by the behavioral psychologist B. F. Skinner, proposes that language is learned when other persons in the child’s environment respond to the child’s use of language [1]. According to Skinner, reinforcement is defined as an event that follows a behavior and increases the future probability of that behavior. When children make speech sounds, others respond in a positive way to these sounds, which reinforces these behaviors and causes the child to engage in them more often [1]. According to this theory, adults gradually shape (Shaping refers to the training of a behavior through the reinforcement of behaviors that are increasingly close approximations of the desired behavior. After a closer approximation is acquired, the other approximations are no longer reinforced. This process continues until the organism acquires the desired behavior [1].) children’s language use by initially reinforcing the production of any sounds, then reinforcing only specific sounds that can be used to form words in the child’s native language, and later only reinforcing adult words used correctly. As the child matures, other people gradually stop reinforcing language use acceptable in young children and begin to reinforce only the acceptable adult uses of language. This process continues until the person has achieved the language competency accepted in his or her environment. This theory has been criticized because studies of parent–child interaction have not found evidence that this type of reinforcement of language use actually occurs consistently [2]. However, most scientists recognize that environmental input is essential for language acquisition and can influence and improve language use [1]. The psycholinguistic or nativist model, first developed by Noam Chomsky, proposes that all human beings have an innate ability to learn language. Chomksy referred to the mechanism that facilitates language acquisition as the language acquisition device (LAD). According to this theory, all typical humans are hard-wired to use basic, universal rules of language which exist in all languages [1]. However, transformational rules, which govern grammar, word order, and other differences that are specific to each language, must be learned by the child as he or she matures. According to this theory, children gradually learn the transformational rules of their own language by hearing the speech of other adults and testing out the patterns of speech when they create their own utterances. This explains why children make mistakes by overusing common rules of their language: for example, children may say “mans” instead of the correct term “men” because they have learned to add a final “s” to pluralize a word. However, this theory has been criticized because it fails to recognize the effects that social interactions and the environment can have on language acquisition and use [1]. The sociolinguistic theory proposes that language is learned through social interactions which cause the child to associate meanings with words used in social contexts. According to this theory, language acquisition begins when a child begins to learn language as caregivers imbue a child’s actions with meaning when they respond to early communication attempts [1]. After social communication is established, caregivers model speech and, when the child imitates their speech, provide feedback that confirms, corrects, or expands the meaning and function that various utterances have when used in a social context. Thus, the communication of intentions and desires first begins in nonverbal forms; after this is established, the child learns to use verbal language to communicate. This theory accepts the view that an innate LAD may exist, but proposes that a social support system is necessary for language acquisition to occur successfully [1]. Relevance to Childhood Development Clearly, language use is one of the most important skills learned in childhood. Knowledge of theories and Language Development developmental milestones related to language acquisition can be helpful to parents, caretakers, and educators who wish to design educational and play activities that are suited to specific age groups. Appropriate use of milestone information also can be helpful for identifying problems with speech, language, or hearing. However, parents should also consider the fact that developmental milestone charts provide only approximate information and that individual variation is expected [1]. Understanding the different theories of language acquisition also can aid parents and guardians in selecting interventions for children with language delays or disorders and evaluating the different interventions offered by professionals. References 1. 2. Owens, R. E. (2001). Language development: An introduction (5th ed.). Needham Heights, MA: Allyn and Bacon. Reisberg, D. (2006). Cognition (3rd ed.). New York: W. W. Norton and Company. Language Development LORETTA C. RUDD, HEATHER M. KELLEY Texas Tech University, Lubbock, TX, USA Definition Language development is a higher level cognitive skill involving audition and oral abilities in humans to communicate verbally individuals’ wants and needs. Description Language is a complex system involving several components. The components of language include phonology, semantics, syntax, and pragmatics. Language development occurs in a fairly predictable fashion. Most typically developing children acquire the skills in each of the four areas by the end of their ninth year of life. While some children may develop more quickly than this, others may develop a bit slower. The important issue is that language develops in a typical sequence across all four areas. The area of phonology includes the sounds of speech. Most typically developing children have acquired all speech sounds of their first language by the end of their ninth year. The typical order of phonological development begins with the sounds produced at the front of the month and progresses to complex blends of sounds. L The second component of language development is semantics, or the meaning of words. It is remarkable that infants begin with no words at birth and typically produce upwards of 250 words by the end of the second year of life. By the time children are 6 years old, they typically have a working vocabulary of 10,000 words! Children who are growing in language-rich environments may have even larger vocabularies. Syntax, or sentence structure, is the third component of language development. As children develop language they begin to use more complex sentence structures. They progress from using one-word utterances (12–18 months), to two-word utterances (18–24 months), to three-word utterances (24–30 months), and finally they are capable of using complex sentences that join more than one thought or event. Most typically developing children have mastered the rules of adult syntax by age 5. The final component of language development is pragmatics. Pragmatics is an understanding of how we use language to communicate with others. Pragmatics includes the social conventions of a culture, such as, politeness, turn-taking routines, non-verbal cues that indicate the listener understands, and cultural variations of these. Relevance to Childhood Development Language development does not begin when children utter their first words around the end of the first year of life. Indeed, language development begins even before birth! There is evidence to indicate that newborns prefer human voice to other sounds and can even recognize their own mother’s voice over voices of other humans. The amount of talk directed at the young child is strongly linked with children’s vocabulary growth and in turn their future reading and writing skills. Children who are reared in language-rich environments do significantly better in reading and writing than children reared in impoverished environments. The critical element of language development to child development is that language development is at the root of most cognitive, social and emotional tasks associated with later success in school. References 1. 2. 3. 4. Berk, L. E. (2006). Development through the lifespan (4th ed.). Boston, MA: Allyn & Bacon. Essa, E. L. (2003). Introduction to early childhood education (4th ed.). Clifton Park, NY: Delmar Learning. Gleason, J. B. (Ed.). (2001). The development of language. Boston, MA: Allyn & Bacon. Trawick-Smith, J. (2006). Early child development: Multicultural perspective (4th ed.). Boston, MA: Allyn & Bacon. 865 L 866 L Language Disorders Language Disorders ▶Central Auditory Processing Disorder ▶Communication Disorders Latent Variables ▶Variables, in Experimental Developmental Research Laterality Language Impairments in Children ▶Central Auditory Processing Disorder ANNA MAZUR-MOSIEWICZ, RAYMOND S. DEAN Ball State University, Muncie, IN, USA Synonyms Cerebral lateralization; Handedness; Lateral dominance; Split brain; Unilateral hand preference Definition Language Learning ▶Language Acquisition Language Variety ▶Dialect Laterality, which is often referred to as unilateral hand preference or handedness, is the preference for one side of the body over the other. Examples include righthandedness and left-footedness. Laterality is related to cerebral lateralization. Laterality is crucial to understanding language functions because of their association with the dominant hemisphere of the brain. In most cases, handedness is genetically determined; however, early trauma or prenatal events are known to affect the adult and preference. Left hand preference that is due to an early hemisphere lesion is referred to as pathological left-handedness [1]. Description Language-Based Reasoning ▶Verbal Intelligence Laplace-Gaussian Curve ▶Normal Curve Latent Learning ▶Learning The reason for hand preference is not completely understood; however, there are small but significant anatomic differences between the dominant and non-dominant hemispheres. For example, the planum temporale tends to be larger in the dominant hemisphere. Also the sylvian fissure and occipital horn tends to be longer in the dominant cerebral hemisphere. Even though there is no clear explanation as to why left-handedness occurs, traditional hypothesis suggest that the left-hand preference is a result of the left-hemispheric disease in early life, which also explains why there is more left-handed individuals among the learning-disabled or cognitively impaired populations than among right-handed individuals [1, 3]. Laterality reflects the functional supremacy of one of the cerebral hemispheres. The majority of humans displays the left cerebellar dominance. Generally, each cerebral hemisphere controls the contralateral side of the body (i.e., left cerebral hemisphere is controls the right side of the body) including muscular control, sensory input, and Laterality other lateralized functions that are associated with a particular hemisphere. This pattern is not clearly established in all individuals. In fact, many individuals are mixed-dominant and not completely right-handed or left-handed, but they tend to favor one hand for complex tasks [1]. Studies estimate that about 90–95% of all adults display general right-handed preference. In early childhood, only 70% of children present right-handedness; yet, in middle and late adulthood, the percentage of righthanded individuals increases to 99%. This change is explained partially by the practice of forcible repression of left-handedness and the accommodation of lefthanders to tools and norms of the right-handed environment. About 95–99% of right-handers have lefthemispheric language representation. The majority of non-right-handed (nondexteral) individuals present left cerebral language dominance; however, they are more likely to have atypical language representation (right or bilateral) with the familial history of left-handedness. The incidence of the right cerebral dominance is harder to estimate due to bilateral hemispheric distribution in these individuals. Yet, the incidence of right-hemispheric language dominance in lefthandedness increases linearly with the degree of left-handedness, form 4% in strong right-handers to 15% in ambidextrous individuals and 27% in strong left-handers. General estimations indicate that in nondexterals, 78% is left-hemispheric dominant, 15% have bilateral language distribution, and about 8% present right-hemispheric dominance [1]. In right-handed individuals, aphasia is usually related to left-cerebral lesion. In these individuals, aphasia due to pure right-hemispheric lesion happens only in 1% of cases. Cerebral dominance in ambidextrous and lefthanded individuals is rarely so uniform. In fact, in 60% of left-handed individuals, aphasia is due to lesions in the left hemisphere, and a majority of right-hemispheric aphasias is reported in left-handers. Moreover, language disorders in left-handed patients with right hemispheric lesions are usually less severe and enduring than in righthanded individuals. Thus, it is often proposed that nonright-handed individuals have bilateral representation of language functions [4]. There are several ways that help to determine which hemisphere of the brain is the dominant one: (1) behavioral outcomes of the brain lesion (the loss or impairment of language functions is usually associated with lesions in the dominant hemisphere); (2) the preference for greater facility in the use of the right or left hand; (3) the preference for greater facility in the use of the right or left foot; (4) the arrest of speech in association with a focal seizure L 867 or after electrical stimulation of the anterior language area during a surgical procedure; (5) injection of sodium amytal into the left internal carotid artery, which produces a one or 2-min-long period of mutism that is followed by misnaming, and paraphasic speech if the left hemisphere is the dominant one; (5) dichotic listening test in which different words are presented simultaneously to two ears, yields ear-hemisphere advantage for the dominant cerebral hemisphere; (6) observing the increase in cerebral blood flow during language processing tasks; (7) and lateralization of speech and language functions following the commissurotomic procedure [1]. Laterality and Cognitive Development Left-handers tend to perform better than right-handers on visuo-spatial tasks. These group differences are likely related to the fact that left-handers have visuospatial functions mediated in a more diffuse manner by both hemispheres and not localized in the right hemisphere, while right-handers have the visuospatial functions more localized in the right hemisphere. Laterality also is related to cognitive abilities and gender. Left-handed males tend to perform similarly to right-handed females in their superiority on tests of verbal skills and sequential processing, and left-handed females and right-handed males appear to have advantageous visuo-spatial skills and nonverbal auditory processing abilities [4]. Higher proportion of nondexterals than right-handers present extreme cognitive functions. At the lower end of the distribution are individuals whose left-handedness was caused to early brain injury. At the other end are individuals with superior intellectual abilities. These individuals tend to become skilled mathematicians, professional athletes, architects, lawyers, and chess players. Additionally, more left-handers enjoy artistic (manual and graphic) and musical talents [1, 4]. References 1. 2. 3. 4. 5. 6. Adams, R. D., & Victor, M. (1993). Principles of neurology. New York: McGraw-Hill. Fasmer, O. B., Akiskal, H. S., & Hugdahl, K. (2008). Non-righthandedness is associated with migraine and soft bipolarity in patients with mood disorders. Journal of Affective Disorders, 108(3), 217–224. Geschwind, N., & Behan, P. O. (1982). Left-handedness: Association with immune disease, migraine, and developmental learning disorder. Proceedings of the National Academy of Science, 79, 5097–5100. Howieson, D. B., Loring, D. W., & Hannay, H. J. (2004). In M. D. Lezak, D. B. Howieson, & D. W. Loring (Eds.), Neuropsychological assessment. New York: Oxford University Press. Marian, A. (2002). Handedness and brain asymmetry: The right shift theory. New York: Taylor & Francis. McKeever, W. R., & Rich, D. A. (1990). Left handedness and immune disorders. Cortex, 26, 33–40. L 868 L Laughter Laughter TAWNIE CABALLERO, BRETT R. NELSON, LAURA PARRES California State University, San Bernardino, CA, USA Synonyms Cackle; Chuckle; Chortle; Giggle; Guffaw; Snicker Definition An explosive sound that is the sign of amusement. Origin: From the Old English hliehhan, is of onomatopoeic (sound-imitating) origin. Description Laughter is the communication of emotion in a social situation and part of the universal human vocabulary. Laughter may express various emotions such as joy, amusement, nervousness, fear, shame, and even aggression. Laughter is one of the few vocalizations that is shared by humans and non-human primates. Tickling is one of the most common and reliable triggers to human and primate laughter. Researchers have found that laughter is not consciously controlled. It is defined by a specific repeated vowel sound such as “ha ha ha” or “he he he.” Different laugh types differ with respect to emotional dimensions. An associated term “schadenfreude” is defined as laughing at another’s misfortune. Relevance to Childhood Development As early as the first few weeks of life, infants begin experiencing the world through auditory and visual channels. During the first months of development, babies may smile and produce “laughter-like” vocalizations at the sight of a familiar face. The close interaction between mother or caregiver and child fosters healthy attachment. Laughter vocalizations are a naturally occurring part of child development. “Cooing,” cuddling, and tickling will elicit the laughter response in very young infants. As children reach toddler age, they continue to develop socialization by using laughter in communication. Children will often play and laugh to express amusement and silliness with family members and friends. Children usually find humor in silly sounds of cartoons and physical humor. During the schooling years, children may quickly learn the social “norms” among their peers in regards to laughter. Laughter can be used either to include or exclude children from a social group. Humor is often used in a therapeutic way to elicit laughter. Laughter is associated with the reduction of stress and provides a brief escape from stressful events. The phrase “Laughter is the best medicine” is based on current research of the many health benefits. Laughing can reduce vasoconstriction (the narrowing of blood vessels) and may decrease levels of the “stress” chemicals Cortisol and epinephrine. Doctors, such as Patch Adams, M.D., have used humor therapy and clowning in their medical practice for treatment of terminally ill patients to provide coping techniques. In regard to parenting, functions of laughter can vary according to an individual’s perception of their child (ren) and specific kinds of interaction. Skilled therapists can observe interactions between parent and child to identify how laughter is used in relationships. Laughter may be used as a means to negotiate tensions or while discussing delicate issues (nervous laughter). A parent may also use laughter to calm concerns they have about his/her child(ren). Conclusion Laughter is a commonly overlooked, yet universal function of human social communication. The meanings of different types of laughter are relative to human development. In humans as young as toddlers, laughter can be used to include or exclude peers from a specific social group. Health benefits of laughter include stress reduction and the reduction of vasoconstriction and stress chemicals. References 1. 2. 3. 4. Alasuutari, M. (2009). What is so funny about children? Laughter in parent-practitioner interaction. International Journal of Early Years Education, 17(2), 105–118. Klein, A. (1998). The courage to laugh: Humor, hope and healing in the face of death and dying. NY: Penguin Putman. Provine, R. P. (2000). Laughter: A scientific investigation. NY: Penguin Books. Szameitat, D. P., Szameitat, A. J., Wildgruber, D., Dietrich, S., Alter, K., Darwin, C. J., et al. (2009). Differentiation of emotions in laughter at the behavioral level. Emotion, 9(3), 397–405. Law of Effect ELIZABETH G. E. KYONKA West Virginia University, Morgantown, WV, USA Synonyms Principle of reinforcement Law of Effect Definition The Law of Effect is E. L. Thorndike’s description of the principle of connectionism: an individual is more likely to repeat behaviors that are accompanied or closely followed by satisfaction and less likely to repeat behaviors that are accompanied or closely followed by discomfort in a particular situation, when that situation recurs. Description Thorndike’s Law of Effect At the end of the nineteenth century, Edward L. Thorndike pioneered a means of measuring learning. He constructed several chambers, each equipped with an escape hatch that could be opened by a particular mechanism such as depressing a lever or pulling a string. He would place a cat (dog, or chick) in the same “puzzle box” several times and recorded escape latency – the amount of time it took the cat to execute the required mechanism and exit the chamber. Upon succeeding, cats were rewarded with access to food for a brief period. Thorndike deemed a decrease in escape latency over successive trials evidence of “animal intelligence,” or learning. The first time a cat experienced a puzzle box it would explore the box, guided by impulse or instinct, and usually took a long time to escape. Once they had escaped successfully from a puzzle box several times, most cats executed the required escape response quickly. Thorndike [5] attributed the decrease in escape latency to a strengthening of the association between stimulus (puzzle box) and response (whatever action was required to escape). Thorndike [6] described the improvement of performance upon repeated trials as the Law of Effect: " L 869 place. As such, the law of effect can be considered a definition of positive reinforcement (and positive punishment), a key concept for theories of learning in respondent and operant behavior: a reinforcer is anything that strengthens a preceding behavior. Theories of Matching: The Quantitative Law of Effect Herrnstein [4] conducted an ▶operant conditioning experiment in which pigeons pecked at two concurrently-presented options that were reinforced at different rates. For several different reinforcement ratios, the percent of pecks to a particular alternative equaled the percent of reinforcers obtained on that alternative: the relationship between rates of responding and rates of reinforcement was proportional. This observation is a restatement of the law of effect as a description of choice between different alternatives that made it possible for Herrnstein to express the relationship as a mathematical equation: B1 kR1 ¼ B1 þ B2 kðR1 þ R2 Þ ð1Þ In Eq. 1, Bs denote rates of responses, Rs denote rates of reinforcement, k is a constant multiplier that drops out and subscripts 1 and 2 refer to different types of responses (alternatively, a target behavior and all other possible behaviors). The relationship between rates of responses and reinforcement is known as the “matching law” and often appears in its most general form [2]: B1 R1 ¼ s log þ log b ð2Þ log B2 R2 Of several responses made to the same situation, those which are accompanied or closely followed by satisfaction to the animal will, other things being equal, be more firmly connected with the situation, so that, when it recurs, they will be more likely to recur; those which are accompanied or closely followed by discomfort to the animal will, other things being equal, have their connections with that situation weakened, so that, when it recurs, they will be less likely to occur. The greater the satisfaction or discomfort, the greater the strengthening or weakening of the bond (p. 244) In Eq. 2, Variables B, R and their subscripts are as in Eq. 1. The parameter s refers to the sensitivity of responding to reinforcer ratio, and the parameter log b to bias, a constant preference for one alternative that is independent of reinforcer ratio. The original matching law described by Herrnstein is a special case of the generalized matching law. The generalized matching law provides a good description of behavior in a variety of experimental choice procedures [3]. According to Thorndike, the effect of reinforcement is a strengthening of the association between stimulus and response. The corollary effect of punishment is a weakening of the association between stimulus and response. Thorndike’s Law of Effect does not provide any insight into how the association comes about in the first The law of effect and the generalized matching law are best understood in experimental conditions where both response and reinforcer are concrete, discrete and easily measurable. However, the principle applies to all circumstances in which learning occurs, in humans of all ages as well as in cats and pigeons. Relevance to Childhood Development L 870 L Law of Independent Assortment The matching law has been used as a means of describing behavior in applied settings notably including classroom environments. It enables psychologists and educators to quantify and assess on-task or appropriate behavior relative to off-task or inappropriate classroom behavior. Results of empirical studies [1] have produced strategies for reinforcing, both individually and classroom-wide, appropriate behaviors such as homework completion that “may allow educators to increase the probability of students choosing to engage in assigned tasks.” A practiced understanding of the law of effect can be particularly useful when teaching preverbal or nonverbal children. Consistent positive reinforcement of a behavior encourages that behavior, whether it is desirable or no. Many parents will identify with those in this case study of a toddler [7]: While the toddler had been sick for an extended period as an infant, one of his parents or a caregiver would monitor him at bedtime until he fell asleep. If the toddler cried or fussed after he was left alone in his bedroom, an adult would return to tend to him. At bedtime, the toddler’s crying response was strengthened by the satisfaction he received from his parents’ attention. It is no wonder his crying continued after his health returned! When his parents stopped reinforcing the toddler’s unnecessary crying, his tantrums ceased with no apparent ill effects. References 1. 2. 3. 4. 5. 6. 7. Billington, E., & DiTommaso, N. M. (2003). Demonstrations and applications of the matching law in education. Journal of Behavioral Education, 12, 91–104. Davison, M., & McCarthy, D. (1988). The matching law: A research review. Hillsdale, NJ: Lawrence Erlbaum Associates. Grace, R. C. (1995). A contextual model of concurrent-chains choice. Journal of the Experimental Analysis of Behavior, 61, 113–129. Herrnstein, R. J. (1961). Relative and absolute strength of response as a function of frequency of reinforcement. Journal of the Experimental Analysis of Behavior, 4, 267–272. Thorndike, E. L. (1898). Animal intelligence: An experimental study of the associative processes of animals. Psychological Review Monograph Supplement, 2, 1–107. Thorndike, E. L. (1911). Animal intelligence. New York: Macmillan. Williams, C. D. (1959). The elimination of tantrum behavior by extinction procedures. Journal of Abnormal and Social Psychology, 59, 269. Law of Independent Assortment ▶Mendelian Genetics Law of Segregation ▶Mendelian Genetics LBW ▶Low Birth Weight Lead Poisoning AMBER R. WHITED, ANDREW S. DAVIS Ball State University, Muncie, IN, USA Synonyms Plumbism; Saturnism Definition Lead poisoning is a medical condition in which the body contains toxic levels of lead. Description Lead has been put to many uses throughout history. It was mixed into cosmetics and medicines, as well as added to pottery enamel and glass used to make food containers. In more recent times, lead was used for soldering the edges of tin sheets together in order to make cans for preserving food. Lead has been used in pipes for household plumbing, as well as in household paints. It was also added to gasoline. As a result, children and adults were often exposed to toxic levels of lead. In modern times, the primary source of exposure for children is lead in paint. Contaminated dust and soil is the second most common source. Young children are at higher risk of exposure, as they engage in hand-to-mouth activities more frequently than older children and adults [3, 8]. Lead levels are typically measured in micrograms per deciliter (mg/dL) in the blood. The Centers for Disease Control and Prevention [6] recommends individual intervention for children with a blood level of 15 mg/dL or higher and community interventions in areas where many children have blood levels of 10 mg/dL or higher. The average blood lead level in the United States is 2 mg/dL. Symptoms of early or mild lead poisoning (about 25–60 mg/dL) often include digestive problems, such as nausea, loss of appetite, or constipation. Fatigue and difficulty sleeping may be noted. Individuals may develop Learned Helplessness anemia. More severe levels of lead poisoning (above 80 mg/ dL) can include kidney disease, encephalopathy, paralysis (lead palsy), or partial or total blindness. Some individuals may have a blue line along the gum line, faintly at mild levels and more pronounced with severe exposure, which is unique to lead poisoning; however, many individuals do not develop this symptom. If left untreated, severe lead poisoning may result in convulsions, coma, or death [1–3, 5, 7, 8]. The primary method of treating lead poisoning is chelation therapy. The most common chelating agents used are penicillamine, mese-2,3-dimercaptosuccinicacid (DMSA), ethylenediaminetriacetate (EDTA), and 2,3dimercaptopropanol (BAL). Penicillamine and DMSA are taken orally and are more commonly prescribed for mild or chronic cases and when treating children. EDTA and BAL are administered by injection and are used for acute lead poisoning. When used with children, injections are typically intramuscular. Proper nutrition is very important during chelation therapy, as the agents used can bind to essential minerals, such as zinc and iron [2, 9]. Relevance for Childhood Development Prenatal exposure to lead has been associated with spontaneous abortions and premature births [10]. Although 80 mg/dL is typically identified as severe exposure, encephalopathy has been found as low as 65 mg/dL. Signs of encephalopathy in children may include restlessness, drowsiness, difficulty concentrating, headache, and vomiting. Seizures may also be noted [4]. Lead poisoning has been found to have a negative impact on the performance on intelligence tests, even at mild levels. Deficits in visual-motor coordination are common. Behavior disorders may develop, with signs of aggressiveness or destructiveness. Children with lead poisoning have been found to be absent from school more frequently, as well as to have higher rates of school failure. Academically, children often perform more poorly on school work, especially verbal activities, such as reading and vocabulary. Auditory processing skills may be weakened. Reaction times tend to be slower for children with lead poisoning [4, 8]. Research has been inconsistent in determining the permanence of deficits for children following treatment for lead poisoning. Some studies have found children can improve with reduction of lead levels, while other studies have found continued deficits. Reduction of environmental exposure is critical to treatment of lead exposure, as reexposure is more likely to cause permanent damage to the central nervous system, even when the second exposure is at a low level [4, 9]. L 871 References 1. Anzelmo, V., & Bianco, P. (1995). Gastrointestinal and hepatic effects of lead exposure. In N. Castellino, P. Castellino, & N. Sannolo (Eds.), Inorganic lead exposure: Metabolism and intoxication (pp. 419–422). Boca Raton, FL: Lewis Publishers. 2. Castellino, N. (1995a). Clinical presentation of human lead poisoning. In N. Castellino, P. Castellino, & N. Sannolo (Eds.), Inorganic lead exposure: Metabolism and intoxication (pp. 287–296). Boca Raton, FL: Lewis Publishers. 3. Castellino, N. (1995b). The history of lead poisoning and uses of lead over the centuries. In N. Castellino, P. Castellino, & N. Sannolo (Eds.), Inorganic lead exposure: Metabolism and intoxication (pp. 3–11). Boca Raton, FL: Lewis Publishers. 4. Castellino, P., Anzelmo, V., Bianco, P., Mattei, O., & Castellino, N. (1995). The neurological toxicity of lead. In N. Castellino, P. Castellino, & N. Sannolo (Eds.), Inorganic lead exposure: Metabolism and intoxication (pp. 297–337). Boca Raton, FL: Lewis Publishers. 5. Castellino, P., Bologna, L., & Castellino, N. (1995). Lead and the kidney. In N. Castellino, P. Castellino, & N. Sannolo (Eds.), Inorganic lead exposure: Metabolism and intoxication (pp. 339–367). Boca Raton, FL: Lewis Publishers. 6. Centers for Disease Control and Prevention. (2005). Preventing lead poisoning in young children. Atlanta, GA: Centers for Disease Control and Prevention. 7. Fabri, G., & Castellino, N. (1995). Lead and the erythropoietic system. In N. Castellino, P. Castellino, & N. Sannolo (Eds.), Inorganic lead exposure: Metabolism and intoxication (pp. 369–401). Boca Raton, FL: Lewis Publishers. 8. Farquhar, D. (1994). Lead poisoning prevention: A guide for legislators. Denver, CO: National Conference of State Legislatures. 9. Millstone, E. (1997). Lead and public health. Washington, DC: Taylor and Francis. 10. Sabatelli, G., Sacco, A., & Castellino, P. (1995). Lead and the reproductive system. In N. Castellino, P. Castellino, & N. Sannolo (Eds.), Inorganic lead exposure: Metabolism and intoxication (pp. 423–436). Boca Raton, FL: Lewis Publishers. Learned Helplessness LEAH E. JOHNSON, MATTHEW C. LAMBERT Texas Tech University, Lubbock, TX, USA Definition The pattern of attributions and behaviors that leads an individual to see no connection between the behavior and the outcomes resulting in feelings of hopelessness, depression, and passivity [5]. Description Learned helplessness is the perception of little or no relation between one’s behaviors and outcomes. Learned helplessness theory assumes individuals seek explanations for events, particularly negative events such as school failure, L 872 L Learning interpersonal problems, poor health, or loss in sports. These explanations and the attributions that underlie them affect expectations for future events. These future expectations then determine behavioral responses, including passivity, anxiety, and depression. Children who develop learned helplessness tend to attribute their failures to a lack of ability. However, when these children succeed they attribute it to external factors, such as luck, rather than ability [5]. The theory of learned helplessness was first proposed in 1967 by Steven Maier and Martin Seligman when they were graduate students at the University of Pennsylvania. The students were involved in a series of experiments concerning negative reinforcement using dogs. In these experiments, a group of dogs received uncontrollable shocks. These dogs were then placed in a situation when they could control the shocks received. The dogs did not display any learning in the new situation- lying passively in the box while receiving shocks that could be controlled, unlike the control group and the dogs that received controllable shocks through the duration of the experiment. Similar results were found in later experiments with rats, monkeys, cats, and humans. From these first experiments, Seligman and others developed their theory of learned helplessness. Seligman’s theory of learned helplessness is composed of three components: contingency, cognition, and behavior. Contingency is the outcome of a person’s actions; that is the result experienced due to a person’s behavior. Cognition is the person’s perception and explanation of the outcome or contingency. Thirdly, behavior is the action a person takes in response the contingency and cognition. Learned helplessness is similar to Weiner’s attributional model, particularly the cognition piece of the theory. Under the theory of learned helplessness, Seligman proposed that people differ in their explanatory, or attributional, style. Research shows that there are consistent individual differences in explanatory style. Some people tend to attribute events to internal, stable, and global causes. Such a student may explain a failure on an exam by saying that he or she is stupid and just cannot learn that subject. Explanatory style appears to generalize to new situations. The generalizability of explanatory style or cognition is more like a trait. The generalizability of learned helplessness along with uncontrollability of events can help explain depression in some people. Seligman proposed that the uncontrollability of an aversive event enhances the fear-arousing characteristics of the event and leads to depression if the experience is prolonged, intense, or becomes frequent. Seligman also contended that the helplessness he observed in his experiments with the dogs was parallel with severe depression in humans. Some similarities include the failure to solve problems that are solvable and a lack of initiation of action. He also noted that like chronic depression, helplessness can be difficult to break up once it established. Learned helplessness cannot explain all facets of every case of depression, but it may identify a set of cognitions that are involved in at least some cases. Relevance to Childhood Development When children with learned helplessness encounter a difficult task, they experience an anxious loss of control and do not persist. Over time, the ability of children with learned helplessness does not predict their performance [1]. These children do not develop the metacognitive and self-regulatory skills necessary for high achievement because they do not recognize the relationship between behaviors and outcomes. Children who have developed learned helplessness become involved in an ongoing cycle of a lack of effective learning strategies, reduced persistence, and a sense of loss of control [1]. References 1. 2. 3. 4. 5. Berk, L. E. (2007). Development through the Lifespan (4th ed.). Boston: Allyn & Bacon. Mook, D. (2004). Classic experiments in psychology. Westport, CT: Greenwood Press. Overmier, J. B. (2002). On learned helplessness. Integrative Physiological & Behavioral Science, 37(1), 4–8. Peterson, C., Maier, S. F., & Seligman, M. (1993). Learned helplessness: A theory for the age of personal control. New York: Oxford Press. Schunk, D. H., Pintrich, P. R., & Meece, J. L. (2008). Motivation in education: Theory, research, and applications (3rd ed.). Upper Saddle River, NJ: Pearson Education. Learning DANIEL PATANELLA New York City Department of Education, New York, NY, USA Synonyms Behaviorism; Cognitive-behaviorism; Conditioning; Latent learning; Literacy; Neo-behaviorism; Social learning Definition Learning refers to changes in behavior and cognition as the result of experience. Traditional learning theory is Learning closely associated with behaviorism, cognitive-behavioral research, and an empiricist-associationist philosophy. Description As a psychological discipline, learning refers to changes in behavior and changes in cognition as the result of experience. Traditional learning theory is closely associated with behaviorism, cognitive-behavioral research, and an empiricist-associationist philosophy. A broad distinction may be drawn between conditioning, as represented by Watson [10] and Skinner [7] and the eclectic cognitive-behavioral learning perspectives of such psychologists as Tolman [9] and Bandura [1]. Regardless of their theoretical diversity, all learning theorists subscribe to the behaviorist maxim that the proper dependent variables in psychological research should be observable, verifiable behaviors. Conditioning Conditioning refers to any process by which an organism acquires new behaviors through repeated experience. There are two main types of conditioning. The first is known as classical conditioning, represented by such researchers as Pavlov [5] and the Watson [10], who popularized the term “behaviorism.” The second, known as operant or instrumental conditioning, derives from the works of Skinner [7] and his followers. Classical conditioning is a form of learning in which an organism comes to associate one stimulus with another, usually prompting a behavior previously associated only with the first stimulus. It is concerned with the re-association of a reflexive behavior to a formerly neutral stimulus. Operant conditioning is a form of learning primarily concerned with the effects of reinforcement and punishment upon behaviors. The behaviors addressed by operant conditioning are much broader in scope than the reflexes of classical conditioning. Within classical conditioning, several components of the conditioned response may be measured and serve as the dependent variable of interest. The amount of time it takes for an organism to respond to a conditioned stimulus is referred to as “latency,” the strength of the response is referred to as “magnitude,” and the likelihood that the conditioned response will occur at all is called “probability.” Examination of these three aspects of learned behaviors has partially led to two important and influential elaborations of our understanding of classical conditioning, namely opponent-process theory, and the RescorlaWagner theory. The opponent-process theory, largely developed by Solomon [8], provides an associationist context for explaining certain instances (such as habituation to drugs) in which the conditioned response becomes L the opposite of the unconditioned response. The RescorlaWagner theory, created by Rescorla and Wagner [6] allows for mathematical prediction of responses based upon the given trajectory of a learning curve, offers a possible learning-based explanation on habituation to repetitive stimuli and also helps explain how organisms distinguish among multiple conditioned stimuli at any given time. Operant conditioning, in contrast, is not as dependent upon reflexive behavior and is primarily concerned with the effects of reinforcement and punishment upon behaviors. Operant conditioning focuses on the consequences of behaviors, and what makes learned behaviors stronger or weaker. Behaviors that are reinforced are likely to persist whereas lack of reinforcement will likely result in a decrease in the behavior. Ferster and Skinner [2] distinguished among four different schedules of reinforcement in Schedules of Reinforcement (1957), and their definitions have become part of standard operant conditioning lexicon. These schedules of reinforcement have been observed in both the laboratory and the real world, and behaviors reinforced using unpredictable schedules are not only highly resistant to extinction but will also continue long after reinforcement has ceased. Series of discrete behaviors can be combined in lengthy chains, resulting in very complex learning and the actual reinforcements used can be far removed from the typical biologically-based primary reinforcements that one normally associates with laboratory research. The Skinnerian concept of “radical behaviorism” conceptualizes even thought processes as subject to the rules and laws of conditioning. Neo-Behaviorism and Social Learning In contrast to the orthodoxy of classical and operant conditioning, neo-behaviorism is a set of diverse theories that allows for the inference of nonobservable constructs such as motivation and internal states. (As is evident from both the Rescorla-Wagner and opponent-process theories, however, classical and operant conditioning do include complex and abstract theorizing.) Social learning bridges the gap between behaviorism and social psychology. The work of both Guthrie [3] and Hull [4] is primarily of historical interest, yet both neobehaviorists introduced important concepts to learning theory. Guthrie stressed the role of contiguity in learning, elaborating upon the necessity of properly linking the unconditioned and conditioned stimuli during classical conditioning and reconceptualizing forgetting as the establishment of new contiguities that successfully competed against the old ones. Hull attempted not only to incorporate the mathematical rigor of proofs and postulates into learning, but also stressed the importance of intervening variables, such as drive, habit 873 L 874 L Learning Difficulty strength, and incentive value of the reinforcement. The work of both researchers helps point the way toward contemporary neural network cognitive psychology. Tolman [9] is considered the father of cognitive behaviorism. Set apart from both classical and operant conditioning, Tolman’s system examined learning aside from the confines of strict minimalist environments, preferring to use mazes rather than puzzles or Skinner boxes in the laboratory. Tolman reported that his lab rats were able to learn the routes of their mazes even prior to reinforcement, as evidenced by their shorter than expected latencies when reinforcement was finally introduced; he referred to this non-reinforced learning as “latent learning,” a concept that is still current. Tolman also introduced the study of insight into behavioral learning. While insight had been a topic explored by Gestalt psychologists, Tolman studied insight learning within the context of rats in a maze. Both latent learning and insight learning are similar in that neither seems to be strict stimulus-response learning, and both make use of what Tolman called a “cognitive map,” a broad purely mental schematic of the immediate environment to be utilized in order to behave efficiently and solve problems. Social learning theory, as introduced by Bandura and elaborated upon by subsequent researchers, is even more removed from traditional behaviorist tradition. According to social learning theory, it is not necessary to be a participant in an activity in order to learn. Rather, by observing the actions of others, one can learn vicariously through modeling. This is largely learning through imitation, an aspect of learning previously overlooked by other theorists. Initially, the theory focused on the acquisition of antisocial behavior in children but the utility of social learning theory has broadened considerably, and social learning theory is not only an integral part of contemporary learning theory but also an essential component of many behavior modification programs. Acknowledgement This work represents the scholarship of the author and does not imply any official position of the New York City Department of Education. References 1. Bandura, A. (1977). Social learning theory. New York: General Learning Press. 2. Ferster, C. B., & Skinner, B. F. (1957). Schedules of reinforcement. New York: Appleton-Century-Crofts. 3. Guthrie, E. R. (1935). The psychology of learning. New York: Harper and Brothers. 4. Hull, C. (1943). Principles of behavior. New York: Appleton-CenturyCrofts. 5. Pavlov, I. P. (1902). Lectures on the work of the digestive glands (W. H. Thompson, Trans.). London: Charles Griffin. 6. Rescorla, R. A., & Wagner, A. R. (1972). A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and non-reinforcement. In A. H. Black & W. F. Prokasy (Eds.), The psychology of learning and motivation (Vol. 4). New York: Academic Press. 7. Skinner, B. F. (1938). The behavior of organisms. New York: AppletonCentury-Crofts. 8. Solomon, R. L. (1980). The opponent process theory of acquired motivation. American Psychologist, 35, 691–712. 9. Tolman, E. C. (1932). Purposive behavior in animals and men. New York: Century. 10. Watson, J. B. (1924). Behaviorism. New York: Norton. Learning Difficulty ▶Learning Disabilities Learning Disabilities TAMARA BOWLIN, SHERRY MEE BELL University of Tennessee, Knoxville, TN, USA Synonyms Developmental dyslexia; Learning difficulty; Learning disorder; Spelling disabilities Definition The most influential definition of learning disabilities is found in the United States federal law Individuals with Disabilities Education Improvement Act (IDEA) 2004: The term “specific learning disability” means a disorder in one or more of the basic psychological processes involved in understanding or in using language, spoken or written, which disorder may manifest itself in imperfect ability to listen, think, speak, read, write, spell, or to do mathematical calculations. Such term includes such conditions as perceptual disabilities, brain injury, minimal brain dysfunction, dyslexia, and developmental aphasia. Such term does not include a learning problem that is primarily the result of visual, hearing, or motor disabilities; of mental retardation; of emotional disturbance; or of environmental, cultural, or economic disadvantage [5]. Learning Disabilities Description Samuel Kirk first proposed the term “learning disabilities” in 1963. When the initial United States federal special education law was passed in 1975, learning disabilities were included as one of the disability categories [3]. The definition remains the same today. The percentage of students identified with learning disabilities rose markedly in the early years following implementation of the federal law, leveling off in the late 1980s. Data from the U.S. Department of Education indicate that students with learning disabilities represent approximately one half of all students receiving special education services and about 5% of the overall school population [17]. There are several potential causes for learning disabilities. Traditionally, learning disabilities have been viewed as resulting from underlying neurological causes [8]. In fact, the term minimal brain dysfunction was used in the 1960s and 1970s as a synonym for learning disabilities [7]. Recent neuroimaging technologies (functional magnetic resonance imaging or fmri) have enabled scientists to pinpoint brain activity associated with academic tasks such as reading. There are documented differences in the brain functioning of individuals with learning disabilities, specifically dyslexia while reading [15]. These findings provide evidence that brain functioning differences are associated with learning disabilities. In addition, there is growing evidence linking learning disabilities to genetics. For example, learning disabilities has a recurrence rate of approximately 35–45% in susceptible families. This finding indicates that a single gene may be a contributing factor [10]. For some individuals, there appears to be a connection between genetic and environmental factors. Specifically, parents who have experienced reading difficulties may be likely to read less to their children [8]. Other environmental factors (e.g., children ingesting lead paint and alcohol and/or drug abuse by an expectant mother) can also lead to a child being at-risk for learning problems. The federal law recognizes eight specific academic areas in which a student can exhibit a learning disability: (1) listening comprehension (receptive language), (2) oral expression, (3) basic reading skills (i.e., decoding and word recognition), (4) reading comprehension, (5) reading fluency, (6) written expression, (7) mathematics calculation, and (8) mathematics reasoning [5]. Dyslexia, a reading disorder characterized by poor decoding, poor spelling, and slow and dysfluent reading, is the most common type of learning disability [15]. However, many state departments of education do not use the term dyslexia in favor of the more general term, learning disability. Learning disabilities may co-occur with each other along L 875 with deficits in social and emotional disorders, and disorders in attention [4]. In addition, researchers have documented a nonverbal learning disability (NVLD), characterized by difficulties with fluid reasoning, spatial difficulties, organizational difficulties, poor problem solving skills, related mathematical weaknesses, and the lack of social ability to comprehend nonverbal communication cues [12]. Nonverbal learning disabilities are not specifically included in the federal definition. Characteristics Individuals with learning disabilities may encounter a range of problems in learning. However, no single individual likely displays all of the following characteristics. Individuals with learning disabilities may exhibit difficulty with language, memory, processing speed, and/or motor skills. These difficulties may result in poor cognitive strategies for learning, oral language difficulties, reading difficulties, writing difficulties, mathematical difficulties and/ or poor social skills [7]. Attention problems are symptomatic for many students. Some characteristics are more likely to be exhibited at certain ages (e.g., children are more likely to be hyperactive than adolescents). Boys are four times more likely to be identified with a learning disability than girls, although there may be an equal number of girls with learning disabilities who go unidentified due to biological causes, cultural factors, or expectation pressures [7]. Learning disabilities become evident at different stages of life with the greatest impact occurring between the ages of 9 and 14 [7]. Assessment and Eligibility for Special Education Services According to the guidelines of IDEA 2004, states may choose from a select number of assessment methods, including the IQ-achievement discrepancy method and the response to intervention method, to determine if a student is eligible for special education services under the learning disability category [5]. Prior to 2004, the IQ-achievement discrepancy model was used to identify a “gap” between a student’s achievement and intellectual ability. Using this method, a child may be identified with a learning disability if he/she exhibits a severe discrepancy between achievement and intellectual ability in one or more of several academic areas under the learning disability category. However due to criticism that the IQ-achievement discrepancy model is a “wait to fail” method that does not yield information useful for academic interventions, beginning in 2004, states are no longer required to employ the IQ-achievement L 876 L Learning Disabilities discrepancy model. Instead, states “must permit the use of a process based on the child’s response to scientific, research-based intervention”; and “may permit the use of other alternative research-based procedures for determining whether a child has a specific learning disability” [11]. The percentage of students identified as having a learning disability varies depending on the criteria used to determine eligibility. With increased pressure to implement response to intervention (RTI) strategies prior to referral for special education, it is hoped that the percentage of students in need of special education services will decrease. Ideally, insuring that all students receive appropriate instruction, beginning in kindergarten, and monitoring progress routinely will result in more effective instruction. Despite controversy over the best way to assess learning disabilities, the construct of learning disabilities as characterized by intraindividual cognitive and academic strengths and weaknesses is valid [6]. “Fundamental to the concept of [learning disability] is the idea of ‘unexpected’ underachievement [13]. That is, individuals who are generally capable experience unexpected difficulty, based on specific cognitive processing weaknesses, in mastering certain academic tasks. For example, dyslexia has been characterized as a weakness “in a sea of strengths” [15, p. 58]. According to Wolf, individuals with learning disabilities can often also be highly creative thinkers or artists [18]. The National Organization on Disability provides information on transition to adulthood for individuals with learning disabilities, including post secondary education and employment [9]. Although individuals with disabilities are twice as likely not to complete college as peers without disabilities, there are special services provided for individuals with disabilities at the post secondary level. The employment rate (full or part time) for individuals with disabilities is only 35% as compared to the employment rate of individuals without disabilities at 78%. By promoting self-advocacy skills, educators can help students make successful transitions from high school to adulthood. IDEA, Section 504, and the Americans with Disabilities Act (ADA) provide overlapping protections to help ensure individuals have equal opportunities, are able to fully participate in their community, live independently and become economically selfsufficient [1, 14]. Learning disabilities are not isolated to the United States, but have been observed across cultures and languages. For example, there is documented evidence that individuals may experience difficulty learning both alphabet-based languages (such as English) and logographic or pictorial systems (such as Chinese) of written language [7]. Many famous, talented individuals are reported to have learning disabilities, including: Alexander Graham Bell, Winston Churchill, Cher, Tom Cruise, Walt Disney, and Magic Johnson. Effective Education of Students with Learning Disabilities References Early, effective instruction is important for minimizing the impact of learning disabilities. For early childhood students, researchers recommend embedding learning opportunities by incorporating practice into daily activities, and capitalizing on student’s interests and motivation [2]. To successfully meet the needs of students with learning disabilities across all grades, teachers can differentiate instruction by using more than one instructional methodology. In order to meet the various academic needs of individuals, intervention strategies may include: increasing a student’s access to instructional materials in a variety of formats, expanding test-taking options, extended time on tests, adjusting the complexity and nature of content material, providing accommodations, peer tutoring, direct instruction, explicit teaching, active and authentic learning opportunities, scaffolded instruction, reciprocal teaching and learning strategy instruction [7, 16]. Increasingly, technology (such as text-to-speech software and word processing programs) are useful for students with learning disabilities. 1. Americans with Disabilities Act (ADA). (1990). (PL 101–336). 2. Bricker, D., Pretti-Frontczak, K., & McComas, N. (1998). An activity based approach to early intervention (2nd ed.). Baltimore: Brookes. 3. Education for All Handicapped Children Act of 1975 (1975). 20 U. S. C. } 1401 et seq., Pub. L. No. 94–142 , 94th Congress, First Session. 4. Fletcher, J. M., Lyon, G. R., Fuchs, L. S., & Barnes, M. A. (2007). Learning disabilities: From identification to intervention. New York: The Gilford Press. 5. Individuals with Disabilities Education Improvement Act of 2004. Public Law 108th Cong., 2nd session. (December 3, 2004). 6. Learning Disabilities Roundtable. (2005). 2004 Learning disabilities roundtable: Comments and recommendations on regulatory issues under the individuals with Disabilities Education Improvement Act of 2004 Public Law 108–466. Retrieved December 18, 2006, from http:// www.ncld.org/index.php?option=content&task=view&id=278 7. Lerner, J., & Johns, B. (2009). Learning disabilities and related mild disabilities: Characteristics, teaching strategies, and new directions (11th ed.). New York: Houghton Mifflin Harcourt. 8. Lyon, G. R., Fletcher, J. M., Shaywitz, S. E., Shaywitz, B. A., Toregesen, J. K., Wood, F. B., et al. (2001). Rethinking learning disabilities. In C. E. Finn, A. J. Rotherham, & C. R. Hokanson (Eds.), Rethinking special education for a new century. Washington, DC: Fordham Foundation. Learning Readiness 9. National Organization on Disability. (2004). N.O.D./Harris survey of Americans with disabilities. (Study No. 20839). New York: Harris Interactive. 10. Pennington, B. (1995). Genetics of learning disabilities. Journal of Child Neurology, 10(1), S69–S77. 11. Regulations for the Individuals with Disabilities Education Improvement Act (2006). U.S. Office of Education. Federal register, August 14, 2006. 12. Rourke, B. P. (1995). Syndrome of nonverbal learning disabilities: Neurodevelopmental manifestations. New York: Guilford Press. 13. Scruggs, T. E., & Mastropieri, M. A. (2006). Response to “Competing views: A dialogue on response to intervention”. Assessment for Effective Intervention, 32(1), 62–64. 14. Section 504 of Rehabilitation Act of 1973. (PL 93–112). 15. Shaywitz, S. (2003). Overcoming dyslexia. New York: Alfred A. Knopf. 16. Turnbull, A., Turnbull, R., & Wehmeyer, M. L. (2007). Exceptional lives: Special education in today’s schools (Vol. 5). New Jersey: Pearson Prentice Hall. 17. U.S. Department of Education, Office of Special Education and Rehabilitative Services, Office of Special Education Programs. (2007). 27th Annual (2005) Report to Congress on the Implementation of the Individuals with Disabilities Education Act. Washington DC. 18. Wolf, M. (2007). Proust and the squid: The story and science of the reading brain. New York: Harper Collins. Suggested Resources Council for Exceptional Children http://www.cec.sped.org//AM/ Template.cfm?Section=Home Learning Disabilities Association http://www.ldanatl.org/ Journal of Learning Disabilities http://ldx.sagepub.com/ Learning Disabilities Quarterly http://www.cldinternational.org/ Publications/LDQ.asp L Learning Goals ▶Mastery Orientation Learning Potential Assessment ▶Dynamic Assessment Learning Readiness MOLLY MILLIANS Marcus Autism Center, Atlanta, Georgia, USA Synonyms Academic readiness; Early academic skills; Pre-academic skills; School-entry skills Definition Learning readiness is the physical, motor, socioemotional, behavioral, linguistic, and cognitive skills indicating preparedness to receive formal educational instruction. Description Learning Disabilities (as Chiefly Used in the United Kingdom) ▶Developmental Disabilities Learning Disability in Math ▶Dyscalculia Learning Disorder ▶Developmental Dyslexia ▶Learning Disabilities 877 The terms learning readiness and school readiness were derived from educational reforms and the outcomes from model early childhood programs. Learning readiness is the observable traits that indicate young children are ready to receive early academic instruction. The term learning readiness is associated with school readiness. However, learning readiness and school readiness refer to different aspects of early learning and education. School readiness refers to the wide range of the skills children need to acquire to enter and to be successful in a school setting. Learning readiness indicates young children’s ability to receive purposeful instruction. In 1989, the National Education Summit was convened to discuss ways to improve education in the United States. The outcome from the National Education Summit was the formation of the National Education Goals Panel and the proposal of the National Education Goals. The National Education Goals are comprised of six objectives to improve education from preschool through twelfth grade in the United States. Learning readiness was included into Goal 1 that stated “by the year 2000, all L 878 L Learning Readiness children in America will start school ready to learn” [5, p. 3]. The National Education Goals were incorporated into the Educate America Act of 1994. In 1992, the National Education Goals Panel attempted to define learning readiness. The National Education Goals Panel identified five dimensions that indicate children are ready to learn and to enter school [10]. The five dimensions were physical well being and motor development, social and emotional development, approaches to learning, language development, and cognition and general knowledge [10, p. 23]. The premise was that adequate development in each of these domains would indicate that children would be ready to learn in school. The National Education Goals Panel dimensions of learning provided a broad description of learning readiness embedded within the term school readiness. Model programs for early child education have attempted to define the skills children need to learn. Many of these programs were designed to prepare economically disadvantaged children for school. The Abecedarian Project in Chapel Hill, North Carolina, has been active since the 1970s. The purpose of the Abecedarian program is to provide quality services in an attempt to prevent developmental delays and low cognitive skills as a result of early deprivation. The program addresses the needs of children 3–6 months of age through early elementary school. Parent involvement and parent education are primary components of the program. Curriculum is geared to address children’s linguistic and communication skills, as well as their cognitive, early academic, social, emotional, and motor skills. The program has been successful in preventing academic failure [9]. Since its inception in 1965, the Head Start Program has provided a comprehensive program to children of low income and at-risk families. This includes children of migrant, homeless, and refugee families. The early goals of the Head Start Program were to encourage ties to the communities, strengthen family interactions, and to ensure the overall well-being of children. This included early educational instruction to prepare children to enter school [10]. More recently, goals for Head Start have shifted to focus on developing children’s cognitive and pre-academic skills. This includes providing language instruction for children who do not speak English as their primary language. In 2007, the Improving Head Start for School Readiness Act (P.L. 110–234) was signed into law. The Improving Head Start for School Readiness Act of 2007 required Head Start Programs to adjust their programs to align with the educational standards established by the No Child Left Behind Act of 2003. The adjustments to the Head Start programs called for systematic monitoring of children’s progress and program accountability through the use of standardized measures, similar to the requirements for public schools outlined in the No Child Left Behind Act of 2003. The Improving Head Start for School Readiness Act of 2007 indicated that children need to have acquired adequate language, listening comprehension, pre-literacy, and early mathematic skills before entering kindergarten. The Improving Head Start for School Readiness Act of 2007 stated that children need to demonstrate the use of critical thinking and problem solving skills, such as categorization. In addition, the law indicated that children need to be able to interact appropriately with peers and adults in order to function in a school environment. The focus of Head Start and other programs for economically disadvantage children has shifted from developing strong community ties to attempting to close the achievement gaps that emerge later in school [8]. As indicated through educational reforms and early childhood educational programs, children require adequate physical, motor, linguistic, behavioral, social and cognitive skills to be prepared to receive formal instruction. Specifically, children need to have developed the abilities to self-regulate, to pay attention, and to interact appropriately with peers and adults. Children need to exhibit the abilities to use language to express ideas, to think through problems systematically, and to begin to acquire early literacy and mathematic concepts [11, 12]. Self-regulation is a foundation for early learning and influences the other components of learning readiness. Self-regulation is the modulation of behavior, emotions, and responses according to the surroundings. Children who are ready to learn are able use self-control and organize their behavior in a structured setting. Self-regulated children are able to comply with rules and follow the expectations of a classroom. Children who are ready to receive formal instruction are motivated to learn more about topics and their surroundings. They demonstrate a lessening of exploratory behavior and begin to move through their environment in an organized manner [4]. Internal motivation includes taking the initiative, setting and reaching a goal, and evaluating performance. Children who are ready to learn exhibit the ability to pay attention. Children, who are able to sustain attention, exhibit an increase in persistence to complete a task or activity. They begin to filter out distractions and inhibit impulsive responses [4]. Interpersonal skills affect learning readiness. Children need to be able to work and play cooperatively with peers. Necessary interpersonal skills include sharing, waiting, Learning Styles and taking turns. Interpersonal skills include listening to the teacher and peers to learn from their ideas [1, 2]. Language, cognitive functioning, and pre-academic skills are primary components for learning readiness. Children need to be able to express their ideas, needs, and wants in order to maneuver a learning environment. Language is also used to mediate children’s responses to their environment. Cognitive skills include the ability to apply and to adjust problem-solving techniques, to make inferences and predictions through thoughtful observations, and to develop an understanding of symbolic relationships [7]. Experience with early literacy and mathematics prepares children for classroom instruction. The acquisition of early literacy and mathematics are predictive of later academic achievement. Pre-reading skills that prepare young children for formal literacy instruction include exposure and use of a rich vocabulary, exposure to the different uses of language, and experiences with the uses of print [3, 8]. Early mathematic knowledge incorporates number skills such as counting using one-to-one correspondence, cardinality, and identifying amounts as more, less, or the same. Through play and interactions children learn to alter values by combining and taking away amounts. Also, preacademic skills need to support formal mathematic instruction that include the ability to distinguishing shapes, patterns, and to recognize spatial relationships [6, 12]. In addition to cognitive and pre-academic factors, the readiness to learn is affected by children’s physical and emotional well being. Children’s readiness to learn is shaped by interactions with caregivers, their environment, and individual predispositions [13, 14]. Research, educational reform movements, such as the call for universal preschool, and comprehensive early childhood programs indicate the need for children and families to have access to quality interventions and programs to assist in preparing children to be ready to learn. 5. Copple, C., Deich, S., Brush, L., Hofferth, S., Anderson, S., Schiffman, J., et al. (1993). Learning readiness: Promising strategies. Washington, DC: US Department of Health and Human Services. 6. Duncan, G., Dowsett, C., Claessebs, A., Magnuson, K., Huston, A., Klebanov, P., et al. (2007). School readiness and later achievement. Developmental Psychology, 46(6), 1428–1446. 7. Howes, C., Burchinal, M., Pianta, R., Bryant, D., Early, D., Clifford, R., et al. (2008). Ready to learn? Children’s pre-academic achievement in pre-kindergarten programs. Early Childhood Research Quarterly, 23, 27–50. 8. Pianta, R. (2007). Early education in transition. In R. Pianta, M. Cox, & K. Snow (Eds.), School readiness and the transition to kindergarten in the era of accountability (pp. 3–10). Baltimore: Brookes. 9. Ramey, G., & Ramey, S. (2004). Early educational interventions and intelligence: Implications for head start. In E. Ziegler & S. Styfco (Eds.), The head start debates (pp. 3–17). Baltimore: Brookes. 10. Schrag, R., Styfco, S., & Ziegler, E. (2004). Familiar concept, new name: Social competence/school readiness as the goal of head start. In E. Ziegler & S. Styfco (Eds.), The head start debates (pp. 19–25). Baltimore: Brookes. 11. Snow, K. (2007). Integrative views of the domains of child function: Unifying school readiness. In R. Pianta, M. Cox, & K. Snow (Eds.), School readiness and the transition to kindergarten in the era of accountability (pp. 197–216). Baltimore: Brookes. 12. Snow, K. (2006). Measuring school readiness: Conceptual and practical considerations. Early Education and Development, 17(1), 7–41. 13. Zigler, E., Gilliam, W., & Jones, S. (2006a). School readiness. In E. Ziegler, W. Gilliam, & S. Jones (Eds.), A vision for universal preschool education (pp. 19–36). New York: Cambridge. 14. Zigler, E., Gilliam, W., Jones, S., & Malakoff, M. (2006b). The need for universal preschool for children in poverty. In E. Ziegler, W. Gilliam, & S. Jones (Eds.), A vision for universal preschool education (pp. 69–88). New York: Cambridge. Learning Skills ▶Cognitive Skills References 1. Bagdi, A., & Vacca, J. (2005). Supporting early childhood socialemotional well being: The building blocks for early learning and school success. Early Childhood Education Journal, 33(3), 145–150. 2. Bierman, K., Torres, M., Domitrovich, C., Welsh, J., & Gest, S. (2008). Behavioral and cognitive readiness for school: Cross-domain associations for children attending head start. Social Development, 18(2), 305–323. 3. Bowman, B., Donovan, M. S., & Burns, M. S. (Eds.). (2001). Eager to learn: Educating our preschoolers. Washington, DC: National Academy Press. 4. Bronson, M. (2000). Self-regulation in early childhood: Nature and nurture. New York: Guildford. L Learning Strategies ▶Memory Strategies Learning Styles ▶Cognitive Styles 879 L 880 L Left Dominant Left Dominant ▶Left Handedness Left Handedness RAYMOND S. DEAN, MATTHEW J. HOLCOMB Ball State University, Muncie, IN, USA Synonyms Left dominant; Sinistral Definition Left-handedness is the expressed consistent preference for the use of the left hand over the right for germane activities in daily life. Description Handedness is defined and categorized in different ways. Most people define handedness as the hand that is preferred for the task of writing. Some researchers define handedness as the hand that is faster for manual tasks. Others define it as the preferred hand, regardless of its abilities. Whereas some people always use their right hand or their left hand for most activities, others use one hand or the other depending on the activity. Still other people have mixed hand usage for most functions. At one time it was thought that left-handedness was a behavioral sign of right cerebral hemispheric dominance for language. Lefthanders usually prefer using their left hand for tasks; however, there is sound method for predicting which hand a lefthander will choose for a given task. Rarely, if ever, is a left handed individual entirely dependent upon using their left hand to accomplish all tasks. Typically, left-handed children usually are more flexible in their hand usage than right-handers; this may be because they are forced to function in a world designed for righthanders. Left-handed children can be placed at a disadvantage due to the prevalence of right-handed tools typical in society. For example, scissors, a very common tool in many children’s lives are often molded in a way that makes them difficult to use for a left-handed child. Additionally, items such as school desks and computer mouse have been traditionally made with right handed individuals in mind. Demographics It has been estimated that 90–95% of the general population is right-handed, making left-handedness relatively uncommon. Overall, left-handedness appears to occur more frequently in men than in women, as well as occurring more frequently in both mono and dizygotic twins. Additionally, research has shown a higher than normal percentage of left-handedness in a number of childhood disorders including autism, mental retardation, and dyslexia. Researchers generally agree that the causes of lefthandedness are commonly considered to be part genetic and part environmental. However, Dean and Rattan [2] and others showed the existence of genetic and pathologic left-handedness. With congenital problems being more likely with pathologic lefthanders over right. There is no standard measure for determining degrees of handedness. Some scientists believe that there are only two types of handedness: right and non-right. These researchers believe that true left-handedness is rare and that most lefthanders are really mixed-handed. Others believe that ambidexterity – the equal use of both hands – is a third type of handedness, and some think that there are two types of ambidexterity. Other scientists believe that handedness should be measured on a continuum from completely right-handed to completely left-handed. Traditionally, this has been measured on a lateral preference scales with very few people exhibiting a pure preference for either left or right handedness. Much of the debate centering on research findings having to do with handedness comes back to the issue of how handedness was determined. With the variety of methods that are available to researchers in defining handedness there has been little consistence in the research. Basis of Handedness The physical evidence for a basis in handedness is not wellunderstood by researchers. Over the years left-handedness has been associated with physical and psychological causes. Additionally, in many cultures left-handedness is regarded with superstitious beliefs and considered due to supernatural occurrences. Until the 1960s, the general theoretical consensus of handedness was that it predicted brain lateralization. Each hemisphere of the brain has some specific functioning that is lateralized to that hemisphere. For example, in the nineteenth century Paul Broca identified the left hemisphere as the major area of speech production in the brain. Left Inferior Frontal Lobe (Anatomically Different Areas, But Regarded as Broca’s Area by Different Sources) Carl Wernicke later identified another region in the left hemisphere that was responsible for language comprehension. These findings help perpetuate the idea that handedness was indicative of brain lateralization. In 1987, Geschwind, Behan, and Galaburda (GBG) published the Theory of Left-Handedness that attributed left-handedness to brain injury or trauma suffered inutero. GBG also suggested that chemical variations in the womb such as higher levels of testosterone could influence handedness. Lifespan Development It is commonly believed amongst researchers that handedness is not a clearly established trait in infants. In fact, many believe that babies are born as ambidextrous, and that changes in handedness can occur several times over the first few years of life. Toddlers usually go through a phase in which the use of one hand is preferred for some activities and not for others. Typically, handedness is decided by the time a child reaches 3 years of age; although it is not uncommon for a child to continue to switch handedness preferences through preschool. Problems Associated with LeftHandedness There are a number of difficulties associated with being left handed and interacting with a predominately right handed environment. Many of these problems are simply annoying, but a few can cause physical injury or serious problems. Due to the overwhelming percentage of people who are right handed, most systems and tools are designed with right-handed individual in mind. For example, most screws are designed for left-to-right turning, which is easier for right handed individuals to accomplish. Some other items that are designed specifically for right-handed individuals are: scissors, calculators, sports equipment, musical instruments, computers, desks, and telephones. Writing is another area that is generally a problem for children with left-handedness. In many cultures, the avoidance of left-handedness has led to pressure for children who are left handed to learn to write right handed. In the U.S. this was a problem, but seems to be dwindling at least on the part of parents and teachers. Children may still feel pressure to perform tasks such as writing right handed because of peer pressure. Teachers may still label a left-handed child’s writing as sloppy or illegible due to an unconscious reaction to writing that looks different from other children’s. Additionally, children who are left-handed may be more prone to L 881 difficulties with writing as they may hook their wrist to be able to see what they are writing; which can produce sloppy handwriting. There is a general trend over the course of history to attribute a number of bad things to left-handed individuals. For example, in history there are numerous instances where left-handed individuals were association with physical, emotional, and behavioral disorders. While not seen in the same extent today, left-handedness has been shown by researchers to put people more at risk for schizophrenia, bipolar disorder, posttraumatic stress disorder, migraine headaches, and language processing disorders such as dyslexia and stuttering. References 1. 2. 3. 4. 5. 6. 7. Clementz, B. A., Iacono, W. G., & Beiser, M. (1994). Handedness in first-episode psychotic patients and their first-degree biological relatives. Journal of Abnormal Psychology, 103(2), 400–403. Dean, R. S., & Rattan, G. (1986). Cerebral laterality and paired associate learning in young children: A dual processing model. International Journal of Clinical Neuropsychology, 8(4), 145–148. Fasmer, O. B., Akiskal, H. S., & Hugdahl, K. (2008). Non-righthandedness is associated with migraine and soft bipolarity in patients with mood disorders. Journal of Affective Disorders, 108(3), 217–224. Geschwind, N., & Behan, P. O. (1982). Left-handedness: Association with immune disease, migraine, and developmental learning disorder. Proceedings of the National Academy of Sciences, 79, 5097–5100. Marian, A. (2002). Handedness and brain asymmetry: The right shift theory. New York: Taylor and Francis. McKeever, W. R., & Rich, D. A. (1990). Left handedness and immune disorders. Cortex, 26, 33–40. Schachter, S. C., & Devinsky, O. (1997). Behavioral neurology and the legacy of Norman Geschwind. Philadelphia, PA: Lippincott Williams and Wilkins. Left Inferior (Third) Frontal Convolution (Gyrus) ▶Broca’s Area Left Inferior Frontal Lobe (Anatomically Different Areas, But Regarded as Broca’s Area by Different Sources) ▶Broca’s Area L 882 L Leiter International Performance Scale: Revised Leiter International Performance Scale: Revised DAVID MICHALEC Nationwide Children’s Hospital/The Ohio State University, Westerville, OH, USA Definition The Leiter International Performance Scale – Revised (Leiter-R) is an individually administered instrument designed to assess the cognitive functioning of children and adolescents ages 2 years, 0 months to 20 years, 11 months of age. The Leiter was revised in 1997. The Leiter-R was specifically developed for children and adolescents with communications disorders, cognitive delays, English as a second language, hearing impairments, motor impairments, traumatic brain injury, attention-deficit disorder and certain types of learning disabilities as well as other populations (e.g., autism spectrum disorders) for which traditional intelligence tests may not be appropriate or valid. Description The Leiter-R includes two groupings of subtests. The Visualization and Reasoning Battery contains ten subtests and generates Brief IQ (ages 2–20), Full Scale IQ (ages 2–20), Fluid Reasoning Index (ages 2–20), Fundamental Visualization Index (ages 2–4) and Spatial Visualization (ages 11–20) scores. The Attention and Memory Battery also contains ten subtests and generates Memory Screener (ages 2–20), Associative Memory (ages 6–20), Memory Span (ages 6–20), Attention (ages 6–20), Memory Process (ages 6–20) and Recognition Memory (ages 6–20) scores. Additionally, the Leiter-R includes four rating scales, which can be completed the by the examiner, parent, the child or adolescent being tested (Self) and teacher, which provide multidimensional behavioral observations. The current revision of the Leiter-R was organized around four primary issues: the need for early identification of cognitive delays, the need for measurement of small increments of improvement in cognitive ability, the need for a reliable and valid scale of intelligence regardless of language or motor ability and the need for transition planning for entering the world of work. In fitting with the primary focus of the most recent revision, The Leiter-R is particularly useful in the assessment of younger children with little or no language skills including those with expressive and receptive language deficits and those with Autism Spectrum Disorders. This measure allows the evaluator to obtain an estimate of intellectual functioning without being overly concerned that the oral language or verbal mediation required of a verbally administered measure (e.g., traditional measures of intellectual functioning) is negatively impacting the child’s performance. Although many of the tasks from the Visualization and Reasoning Battery are based on a matching paradigm and therefore may not generalize broadly to other cognitive skills, the ability to demonstrate clear cognitive strengths and weaknesses outside of the influence of language functioning is a huge asset for treatment planning. The Leiter-R offers several updates from the earlier version including new normative data (based on 1993 census data), light weight, laminated picture cards and foam shapes that are brightly colored and child friendly and an easel format for administration. The total normative sample matches the US population well on important stratifying variables. Internal consistency reliabilities are adequate although test – retest changes for the composite scores have been found to be somewhat large. Factor analytic studies have supported the theoretical underpinnings of the test. The Leiter-R correlates well with other accepted measures of intellectual functioning including the WISC-III. The Leiter-R is also felt to be largely culturally free and studies have found the measure to be valid across a number of cultural and ethnic groups. References 1. 2. Roid, G. H., & Miller, L. J. (1997). Leiter international performance scale – revised: Examiner’s manual. In G. H. Roid & L. J. Miller (Eds.), Leiter international performance scale – revised. Wood Dale, IL: Stoelting, Co. Sattler, J. M. (2001). Assessment of children: Cognitive applications (4th ed.). San Diego, CA: Jerome M. Sattler, Publisher, Inc. Lesbian ▶Homosexuality Lethargic ▶Hypoactivity Leukemia Leukemia MARGAUX BARNES, AVI MADAN-SWAIN University of Alabama Birmingham, Birmingham, AL, USA Synonyms Acute leukemia Definition Leukemia is a cancer of the blood and blood forming organs, including the bone marrow, lymph nodes, and spleen. Description Leukemia is the most common pediatric cancer diagnosis, comprising approximately 30% of all childhood cancers. Acute lymphoblastic leukemia (ALL) accounts for about 80% and acute myelogenous leukemia (AML) about 15% of pediatric leukemias; while chronic myelogenous leukemia (CML) and juvenile myelomonocytic leukemia (JMML) are infrequent. Annually approximately 3,000 new cases of ALL and 500 of AML are diagnosed in the United States [3]. The hallmark of leukemia is bone marrow dysregulation. The bone marrow makes red blood cells which carry oxygen, white cells, which fight infections, and platelets, which help clot blood. Leukemia is a cancer of the early blood forming cells and most commonly affects the white blood cells, also known as leukocytes. Sometimes certain types of immature white blood cells, often known as blasts, undergo a random mutation that can cause the cells to grow and multiply unchecked. The blasts suppress normal bone marrow function, which results in decreased red blood cells, decreased platelets, and decreased functional white blood cells. Leukemia is diagnosed in all age groups with peak incidence between ages 2 and 5 years of age. Leukemia rates vary by age, gender and race. For example, males are more likely to be diagnosed with ALL as compared to females in children under the age of 15. Similarly, ALL rates are significantly lower in African American children than Caucasian children; but no ethnic differences are noted among children diagnosed with AML [3]. There are no known causes for ALL. However, increased risk for ALL is associated with genetic conditions such as Down syndrome, neurofibromatosis, Schwachman syndrome, Bloom syndrome, Li-Fraumeni syndrome, Klinefelter syndrome, or if a child has received L medications to suppress the immune system such as after organ transplantation. There also is a 2–4 times higher incidence of ALL in siblings than in children in the general population. Finally, children who have received prior chemotherapy or radiation treatment for other types of cancer are also at risk for developing leukemia. Clinically, children may present with low-grade fever, signs of infection, fatigue, increased bruising or bleeding, and facial pallor. When the diagnosis of leukemia is suspected the child is referred to a Pediatric Hematologist/Oncologist for a full evaluation, which includes a thorough physical examination, blood tests, and a needle aspirate of the bone marrow. Based on this work-up, the specific leukemia type is confirmed, and chemotherapy is begun to treat the condition. At diagnosis children are categorized as having low, intermediate, or high risk based on both the child’s clinical features, chromosomal abnormalities noted in the leukemia cells, and response to chemotherapy. Higher risk factors include low or high age (i.e., children under the age of 1 year or older than 10 years of age), a white blood cell count greater than 50,000, leukemia subtype, central nervous system disease (i.e., blasts in the spinal fluid), certain chromosomal alterations in the leukemia cell, and slow response to initial treatment. These factors would require more aggressive treatment. Medical treatment protocols for ALL typically include the following stages: Induction, Consolidation, Delayed Intensification, and Maintenance. The Children’s Oncology Group (COG) conducts randomized clinical trials to determine the best therapy for each treatment phase. The goal of clinical trials is to increase cure rate for leukemia and reduce the toxicity of the therapy. Current ALL standard risk treatment protocols are 2 to 2-and-a-half years for girls and 2-and-a-half to 3 years for boys. After the first 6 months most of the chemotherapy is generally administered on an outpatient basis. High risk ALL protocols may require more frequent inpatient chemotherapy admissions. Treatment for AML usually requires 4–5 months of intensive chemotherapy administered as an inpatient. Some AML patients may receive a bone marrow transplant. Induction is the initial treatment phase for ALL and usually lasts 4 weeks. Children receive chemotherapy orally, intravenously, as well as intrathecally (i.e., injected into the fluid surrounding the brain and spinal cord). The goal of this phase is to induce remission. Remission is defined as an absence of signs and symptoms of leukemia, a return to normal of blood and bone marrow values, and less than 5% leukemia cells in the bone marrow. Approximately 95% of children with ALL achieve remission 883 L 884 L Lexapro® within 4 weeks of beginning therapy. Once in remission the consolidation phase of therapy is initiated and lasts from 4- to -6 months. During this period the child receives repeated cycles of systemic chemotherapy agents as well as continued intrathecal chemotherapy to eliminate any remaining leukemia cells. For certain types of leukemia, or if leukemia cells were present in the spinal fluid at the time of diagnosis, radiation therapy may be given to the brain and the spinal column. During delayed intensification the child receives chemotherapy agents similar to those received in the first 6 months of treatment (i.e., during induction and consolidation). Research shows that both low and high-risk ALL patients benefit from Delayed Intensification. Maintenance therapy is the final phase of treatment and generally lasts 2–3 years. Maintenance is much less intensive than the previous treatment and consists mostly of oral medications administered at home, as well as intermittent intravenous and intrathecal medications given in the outpatient clinic. Bone marrow transplant may be necessary for children with high-risk features including relapse, and treatmentresistant diseases, or other disease subtype factors that increase the likelihood that standard treatment will be unsuccessful. Currently, approximately 75% of children are cured (i.e., they remain disease free 2 years after completion of treatment). More relapses or recurrences occur either on therapy or within 2 years after completion of therapy. Late relapses (beyond 5 years) are rare. If the leukemia returns, another remission will often be achieved with more aggressive medical therapy. Many children will stay in remission with additional chemotherapy, but a bone marrow transplant may be recommended for some children. Approximately 50% of children will be cured from AML with chemotherapy and, if available, a bone marrow transplant using a matched related donor. Relevance to Childhood Development Children vary in the way they cope with the news of their cancer diagnosis and treatment [3, 4]. Coping responses may include withdrawal, becoming very scared or worried, and/or lashing out in anger. During induction the child learns to deal with painful procedures, cope with the physical symptoms and side effects (e.g., nausea, vomiting, fatigue), adjust to interruptions in school and social activities, adjust to the hospital environment, and manage emotional reactions and responses. During the middle to later phase of treatment the child learns to deal with physical side effects (e.g., weight gain on steroids, hair loss), adhere to treatment regimen, and try to maintain academics, social activities, and communication with close friends. After completion of treatment the child learns to acknowledge concerns over relapse or recurrence, make meaning of their cancer experience and shift roles from being a “cancer patient” to being a survivor [1]. Due to improved medical treatment more children are surviving and consequently increased emphasis is being placed on medical, psychological, and learning late effects. Potential medical late effects include short stature, delayed pubertal development, infertility problems, and neurocognitive deficits. Neurocognitive late effects secondary to intrathecal chemotherapy and radiation therapy include problems with executive function including short attention span, problems with organization, decreased processing speed, difficulties with visual-spatial and visual-motor tasks, problems with visual memory, and academic difficulties with reading comprehension and math calculation [2]. Some ALL survivors also are at risk for development of anxiety, symptoms of posttraumatic stress, problems with identity, and decreased self-esteem [4]. However, there also is some evidence of positive growth from going through the cancer experience. References 1. 2. 3. 4. Marsland, A. L., Ewing, L. J., & Thompson, A. (2006). Psychological and social effects of surviving childhood cancer. In R. T. Brown (Ed.), Comprehensive handbook of childhood cancer and sickle cell disease: A biopsychosocial approach (pp. 237–261). New York: Plenum Press. Mulhern, R. K., & Butler, R. W. (2006). Neuropsychological late effects. In R. T. Brown (Ed.), Comprehensive handbook of childhood cancer and sickle cell disease: A biopsychosocial approach (pp. 262–278). New York: Plenum Press. Smith, M. A., Gloeckler-Ries, L. A., Gurney, J. C., & Ross, J. A. (1999). Leukemia. In L. A. Gloeckler-Ries, M. A. Smith, J. G. Gurney, M. Linet, T. Tamra, J. L. Young, & G. R. Bunin (Eds.), Cancer incidence and survival among children and adolescents: united states SEER program, 1975–1995. Bethesda, MD: SEER. Weiner, L. S., Pao, M., Kazak, A. E., Kupst, M. J., & Patenaude, A. F. (Eds.). (2009). Quick reference for pediatric oncology clinicians: The psychiatric and psychological dimensions of pediatric cancer symptom management. Charlottesville, VA: IPOS Press. Lexapro® ANISA FORNOFF Drake University, Ankeny, IA, USA Synonyms Escitalopram Life Events Definition References A prescription medication FDA approved for the treatment of major depressive disorder and generalized anxiety disorders. 1. Description This medication is a selective serotonin reuptake inhibitor available in a tablet or as an oral solution. The recommended starting dose for this medication is 10 mg taken once a day. Maximum suggested dose is 20 mg a day. This medication should only be taken as directed by a doctor. This medication may need to be taken for four weeks before improvement in symptoms is seen. This medication should be taken with or without food. Avoid drinking alcohol. Tell your doctor if you have a history of a seizure disorder or liver disease. Concomitant use in patients taking monoamine oxidase (MAO) inhibitors is not advised. Serotonin syndrome may occur with the use of certain other serotonergic drugs. Some side effects are listed here: headache, drowsiness, constipation, difficulty sleeping, decreased sexual desire, decreased appetite and weight loss, diarrhea, and dizziness. Certain side effects may go away during treatment. Tell your doctor immediately if you notice the following: confusion, irregular heartbeat, muscle pain, shortness of breath, or swelling. If you choose to stop taking Lexapro®, you are encouraged to tell your doctor and slowly taper this medication to prevent withdrawal symptoms. This medication should be stored out of reach of children and pets and away from light, heat, and moisture. 2. 3. 885 Advice for the patient: Drug information in lay language (USP DI, Vol. II, 27th ed., pp. 675–677). Kentucky: Thompson Micromedex, 2007. AHFS drug information (24th ed., pp. 2344–2346). Maryland: American Society of Health-System Pharmacists, Inc., 2008. Lexi-drugs online [database online]. Hudson, OH: Lexi-Comp Inc. Accessed August 5, 2008. Lexical Configuration ▶Syntax Library Therapeutics ▶Bibliotherapy Librelease ▶Chlordiazepoxide Libritabs ▶Chlordiazepoxide Librium Relevance to Childhood Development Lexapro® is not FDA approved for use in children. A medication guide must accompany this medication containing information related to the increased risk of suicidal thinking and behavior in children, adolescents, and young adults compared to those not taking the medication. Doctors will monitor patients closely for worsening of symptoms, change in behavior, and thoughts of suicide. Patients are strongly encouraged to notify their health care provider to report sudden changes in mood, behavior, thoughts, or feelings. Women should let their doctor know if they are pregnant or planning to become pregnant. Talk with your doctor if you plan to breastfeed, as this medication enters the breast milk. L ▶Chlordiazepoxide Life Events BEATRIZ OLAYA GUZMÁN1, CECILIA A. ESSAU2 Edifici B. Universitat Autònoma de Barcelona, Spain 2 Roehampton University, London, UK 1 Synonyms Negative life events; Stressful life events; Undesirable life events L 886 L Life Events Definition Life events have been defined as a social experience or change with a specific onset and course that has a psychological impact on the individual [7]. This definition makes no assumption about the type, duration and effects of the events. Some common examples of life events include parental divorce or separation, school change, house relocations, and bereavement. Description All individuals experience hundreds of life events throughout their life time that differ in magnitude, duration and meaning. Some of these events are major and involve high level of change (e.g., death of a love one), and some events are minor and have little impact on their own (e.g., minor accident). Life events are important as they could facilitate positive growth and adaptation, or they could contribute to illness and disturbances. Studies on life events have focused on two major areas: (1) Description of events throughout the life span: This line of research has focused on the developmental nature of life events and has identified several characteristics of life events. First, some biological (e.g., physical growth) and social events (e.g., school transitions) are age-related in that they occur frequently during childhood and adolescence. Although such life events are part of development, they may be problematic if they occur at different (than expected) point in the life span. Second, although some events are unique of particular individuals, some (e.g., war) may affect on the entire culture. Finally, developmental approach also stresses the importance of historical or cohort effects of events. For example, those who experienced adolescence during the 1930s economic depression have a different event history than those who experienced adolescence during the 1960s economic affluence. (2) Impact of life events during childhood and adolescence: This line of research is concerned with the relationship between life events and psychological/ physical disorders. Some studies investigated the mechanisms through which exert their effects on individuals, and some examined factors that predicted the outcomes of life events on the individual’s development. Assessment of Life Events Impact of life events have traditionally been examined using self-report questionnaires or life events checklists. In such studies, the number of events experienced over a given period of time can be counted. The problem of this method is an assumption that all events have the same effect. Although this problem could be reduced by giving a stress score which lead to change in the child’s life such life change units have been reported to be insensitive to individual differences that surround life events. Another important issue is to determine whether the events are the cause, consequences of psychological disorders, or of it is an illness-related behaviour [15]. A major advantage of using checklists is that they are easy to administer without much training requirement. As such they are economical. Some examples of life events checklists are: Life Events Checklist (LEC; [11]); Life Event Record (LER; [3]), Brief Adolescent Life Event Scale (BALE; [17]), Adolescent Perceived Events Scale (APES; [4]). Another approach to measure life event is through interviews. The use of interview is time consuming, however, this factor is outweighted by the quality of information collected [9]. The ability to collect information surrounding a life event enables the evaluation of the personal meaning that a life event contains [2]. When studying children, it is unclear from whom the information about life event should be collected. For the under 8-year olds, parent’s report is regarded as the most reliable informant because of children’s lack of cognitive skills to recall information in an accurate way, and children’s awareness of important sources of life events. When studying adolescents, adolescents themselves have been considered as the best source of information [13]. Some examples of commonly used interviews for the assessment of life events are: Life Events and Difficulties Schedule (LEDS; [2]), and Stressful Life Events Schedule (SLES; [18]). Relevance to Childhood Development Research conducted during the past few decades have shown life events to be related to the onset of a wide range of psychiatric disorders, such as depressive, anxiety, substance use, and conduct disorders. For example, since the 1970’s, studies have noted the influence of negative/ stressful life events on the onset of depression, and research has shown that stress is specifically predictive of depressive symptoms in children and adolescents [9, 14]. Life events predict subsequent depressive disorder, and those which are chronic in nature (e.g., chronic family turmoil) also influence the persistence of depressive symptoms [6]. The types of life events which act as risk factors for major depressive disorder seem to differ in boys and girls. In Reinherz et al.’s study [16], for example, the death of a parent before age 15, pregnancy, and an early onset of Life Satisfaction health problems (e.g., respiratory disorders, mononucleosis, arthritis and headaches) which interfered with daily functioning were antecedent risks for major depressive disorder in females; in males it was the remarriage of a parent [16]. In a study by [1], depressed adolescents tended to use more negative alternatives (e.g., becoming intoxicated, isolating themselves, or running away from home), whereas the non-depressed adolescents generally used positive alternatives (e.g., minimizing the importance of the events) in dealing with the life events experienced. According to several other authors, major depressive disorder was generally positively correlated with emotion-focused strategies [4] and cognitive avoidance [5], and negatively correlated with problem-focused coping [4]. In Nolen-Hoeksema et al.’s study [14], the association between life events and depressive disorders was related to chronic disruption in the child’s environment; among older children, the impact of life events on depressive disorders was mediated by pessimistic explanatory style, and among girls by selfperceived body image, self-esteem, and self-efficacy. Children who were exposed to high stress levels were especially likely to become depressed if the mothers were currently symptomatic [10]. Thus, the presence of the mother to help buffer the ill effects of stress may moderate the impact of stressors on children’s probability to develop depressive disorders. In Goodyer et al.’s study [8], adolescents whose mothers had a history of psychiatric disorder were exposed to more negative events than those whose mothers had no such history. Thus, both lifetime maternal psychiatric disorder and increased exposure to undesirable life events significantly exerted an increased risk for major depressive disorder in adolescents. It should, however, be stated that life events appear to be a nonspecific risk factor for major depressive disorder; that is, negative life events increase the risk of both depression and a number of other psychiatric disorders. As shown by [12], parental loss before the age of 17 years was significantly related to the presence of five major psychiatric disorders. 5. Ebata, A. T., & Moos, R. H. (1991). Coping and adjustment in distressed and healthy adolescents. Journal of Applied Developmental Psychology, 12, 33–54. 6. Garrison, C. Z., Addy, C. L., Jackson, K. L., McKeown, R. E., & Waller, J. L. (1992). Major depressive disorder and dysthymia in young adolescents. American Journal of Epidemiology, 135, 792–802. 7. Goodyer, I. (1991). Life events, development and childhood psychopathology. Chichester: Wiley. 8. Goodyer, I. M., Cooper, P. J., Vize, C. M., & Ashby, L. (1993). Depression in 11-16-year-old girls: The role of past parental psychopathology and exposure to recent life events. Journal of Child Psychology and Psychiatry, 34, 1103–1115. 9. Goodyer, I. M., Wright, C., & Altham, P. M. (1988). Maternal adversity and recent stressful life events in anxious and depressed children. Journal of Child Psychology and Psychiatry, 29, 651–667. 10. Hammen, C., & Goodman-Brown, T. (1990). Self-schemas and vulnerability to specific life stress in children at risk for depression. Cognitive Therapy and Research, 14, 215–227. 11. Johnson, J. H., & McCutcheon, S. M. (1980). Assessing life stress in older children and adolescents: Preliminary finding with the life events checklist. In I. G. Saranson & C. D. Spielberger (Eds.), Stress and anxiety Vol. 7 (pp. 111–125). Washington, DC: Hemisphere. 12. Kendler, K. S., Neale, M. C., Kessler, R. C., Heath, A. C., & Eaves, L. J. (1992). Childhood parental loss and adult psychopathology in women. Archives of General Psychiatry, 49, 109–116. 13. Monck, E., & Dobbs, R. (1985). Measuring life events in an adolescent population: methodological issues and related findings. Psychological Medicine, 15, 841–850. 14. Nolen-Hoeksema, S., Girgus, J. S., & Seligman, M. E. P. (1992). Predictors and consequences of childhood depressive symptoms: A 5-year longitudinal study. Journal of Abnormal Psychology, 101, 405–422. 15. Paykel, E. S. (1983). Methodological aspects of life events research. Journal of Psychosomatic Research, 27, 341–352. 16. Reinherz, H. Z., Giaconia, R. M., Pakiz, B., Silverman, A. B., Frost, A. K., & Lefkowitz, E. S. (1993). Psychosocial risks for major depression in late adolescence: A longitudinal community study. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 1155–1163. 17. Shahar, G., Henrich, C. C., Reiner, I. C., & Little, T. D. (2003). Development and initial validation of the Brief Adolescent Life Event Scale (BALES). Anxiety, Stress and Coping, 16, 119–128. 18. Williamson, D. E., Birmaher, B., Ryan, N. D., Shiffrin, T. P., Lusky, J. A., Protopapa, J., et al. (2003). The stressful life events schedule for children and adolescents: development and validation. Psychiatry Research, 119, 225–241. References 1. Adams, A., & Adams, J. (1991). Life events, depression, and perceived problem solving alternatives in adolescents. Journal of Child Psychology and Psychiatry, 32, 811–820. 2. Brown, G. W., & Harris, T. O. (1978). Social origins of depression: A study of psychiatric disorder in women. London: Tavistock. 3. Coddington, R. D. (1972). The significance of life events as etiologic factors in diseases of children. I. A survey of professionals. Journal of Psychosomatic Research, 16, 205–213. 4. Compas, B. E., Davis, G. E., Forsythe, C. J., & Wagner, B. M. (1987). Assessment of major and daily stressful events during adolescence: The adolescent perceived events scale. Journal of Consulting and Clinical Psychology, 55, 534–541. L Life Satisfaction DAVID N. MILLER University at Albany, SUNY Division of School Psychology, Albany, NY, USA Synonyms Quality of life; Well-being 887 L 888 L Life Satisfaction Definition Life satisfaction is a cognitive appraisal process in which individuals subjectively assess life quality on the basis of their own unique set of criteria. Description In recent years there has been an increased emphasis on examining the positive aspects of human nature. This movement, known as positive psychology, has been defined as “the scientific study of ordinary human strengths and virtues” ([10], p. 216). One topic within the domain of positive psychology that has attracted substantial interest is how and why individuals, including children and adolescents, experience their lives in positive ways [5]; that is, there has been increased interest in examining those variables that contribute to the development of subjectively perceived life satisfaction. Research on life satisfaction has been conducted from social indicators, marketing, and quality of life perspectives [11]. However, much of the recent research in this area has been most influenced by the work of Diener and his colleagues [1, 2], who conceptualize life satisfaction as one of three important components (the others being positive and negative affect) within the larger domain of subjective well-being. This perspective conceptualizes life satisfaction as “a cognitive judgmental process in which individuals assess the quality of their lives on the basis of their own unique set of criteria” ([9], p. 164). Although the appraisal of life satisfaction is a cognitive one, it is largely based on the positive experiences and emotions that collectively contribute to subjective wellbeing. However, these cognitive judgments are largely independent from an individual’s immediate and emotional interpretation of a particular event; reports of life satisfaction “are believed to transcend momentary emotional experiences within and across life situations and are thus considered more stable than affective states when assessing life quality over time” ([11], p. 28). That said, researchers are recognizing that life satisfaction is tied to specific, concrete experiences, and that it yields unique variance not accounted for by assessing more global life satisfaction indices alone. This has lead to the development of measures that assess satisfaction within specific domains, such as students’ perceptions of school satisfaction [11]. Most of the research on life satisfaction to date has been conducted with adults, with research involving child and adolescent samples having begun only recently. Research suggests that although most children and adolescents are generally satisfied with their lives, a minority appear very dissatisfied [7]. Low life satisfaction is associated with several adverse outcomes, including those related to internalizing problems (e.g., depression, anxiety) and school adjustment. In contrast, high life satisfaction functions as a psychological strength and actively fosters resilience and well-being [7]. For example, in a study examining the characteristics of adolescents who reported high levels of global life satisfaction, Gilman and Huebner [6] found that high life satisfaction was associated with mental health benefits that were not found among youth reporting comparatively lower life satisfaction levels. Moreover, school experiences can strongly influence life satisfaction in children and adolescents. Behavioral contexts (e.g., grades received; in-school conduct), social contexts (e.g., school climate), and cognitive contexts (e.g., academic personal beliefs; attachment to school) associated with schools are all linked to students’ global life satisfaction [11]. Some research has suggested that academic achievement in school is moderately correlated with adolescents’ global life satisfaction [6] and school satisfaction [3]. Suldo and Shaffer [12] found that middle-school students with the highest reported levels of subjective well-being had superior grades in courses and superior scores on standardized achievement tests. In contrast, lower levels of life satisfaction have been associated with problem behaviors in school, including disruptive and acting-out behaviors [11]. Over the past decade, several psychometrically sound life satisfaction scales for children and adolescents have been developed on the basis of unidimensional or multidimensional models. Most reviewed measures to date have adequate internal consistency reliability and acceptable test-retest reliability across several time frames (up to a year), and have also demonstrated strong evidence of various types of validity [4, 11]. To date, most measures have been self-reports and have been primarily used to illustrate similarities and differences between life satisfaction and related psychological constructs, such as self-concept [7]. The assessment of life satisfaction in children and adolescents is still in its beginning stages and more research is needed. It is clear, however, that assessing constructs such as life satisfaction provides a broader, more comprehensive perspective of psychological functioning, and that assessing problems in the absence of strengths provides an incomplete and distorted picture of children and youth [8]. Given that life satisfaction is a meaningful indicator and determinant of well-being in Limbic System children and adolescents, school and clinic-based mental health professionals should become well-versed in its assessment as well as interventions to promote it. References 1. Diener, E. (1984). Subjective well-being. Psychological Bulletin, 95, 542–575. 2. Diener, E., Suh, E. M., Lucas, R. E., & Smith, H. L. (1999). Subjective well-being: Three decades of progress. Psychological Bulletin, 125, 276–302. 3. Gilman, R. (2006). Students who like and dislike school. Applied Quality of Life Research, 1, 139–150. 4. Gilman, R., & Huebner, E. S. (2000). Review of life satisfaction measures for adolescents. Behaviour Change, 17, 178–192. 5. Gilman, R., & Huebner, E. S. (2003). A review of life satisfaction research with children and adolescents. School Psychology Quarterly, 18, 192–205. 6. Gilman, R., & Huebner, E. S. (2006). Characteristics of adolescents who report very high life satisfaction. Journal of Youth and Adolescence, 35, 311–319. 7. Huebner, E. S., Suldo, S. M., & Gilman, R. (2006). Life satisfaction. In G. G. Bear & K. M. Minke (Eds.), Children’s needs III: Development, prevention, and intervention (pp. 357–368). Bethesda, MD: National Association of School Psychologists. 8. Miller, D. N. (2010). Assessing internalizing problems and wellbeing. In G. Gimpel Peacock, R. A. Ervin, E. J. Daly, & K. W. Merrell (Eds.), Practical handbook of school psychology: Effective practices for the 21st century (pp. 175–191). New York: Guilford. 9. Pavot, W., & Diener, E. (1993). Review of the Satisfaction with Life Scale. Psychological Assessment, 5, 164–172. 10. Sheldon, K. M., & King, L. (2001). Why positive psychology is necessary. American Psychologist, 56, 216–217. 11. Suldo, S. M., Huebner, E. S., Friedrich, A. A., & Gilman, R. (2009). Life satisfaction. In R. Gilman, E. S. Huebner, & M. J. Furlong (Eds.), Handbook of positive psychology in schools (pp. 27–35). New York: Routledge. 12. Suldo, S. M., & Shaffer, E. J. (2008). Looking beyond psychopathology: The dual-factor model of mental health in youth. School Psychology Review, 37, 52–68. 13. Suldo, S. M., Shaffer, E. J., & Riley, K. N. (2008). A social-cognitivebehavioral model of academic predictors of adolescents’ life satisfaction. School Psychology Quarterly, 23, 56–69. Life Style ▶Adler, Alfred Lifestyle Mores ▶Cultural Difference L 889 Limbic System CHAD A. NOGGLE1, JOHN JOSHUA HALL2 1 SIU School of Medicine, Springfield, IL, USA 2 The University of Arkansas for Medical Sciences, Little Rock, AR, USA Definition The Limbic System is a network of brain structures that together play a pivotal role in emotional processing and regulation as well as aspects of memory. Description The Limbic System represents one of the three divisions of the Telencephalon, in addition to the Basal Ganglia and the Cerebral cortex. Anatomically, the Limbic System is a network of structures that surround both the basal ganglia and the thalamus [1]. These structures include, but are not limited to, the Hippocampus, Dentate Gyrus, Cingulate Gyrus, Septal areas, Amygdala and aspects of the Diencephalon [4]. From a functional standpoint the Limbic System is best conceptualized as a holistic system as few one-to-one structure-function relationships have been established. Rather, many of the structures included within the system demonstrate overlapping roles in the modulation of the various functions regulated by the limbic system. Specifically, the Limbic System, in concert with aspects of the Frontal lobes and Temporal lobes, are involved in the control of memory and emotion [2]. This corresponds with aspects of emotional processing and regulation as well as aspects of recent memory [4]. Beyond these areas, which are most commonly linked with the interconnections and workings of this network of structures, the Limbic System has also been associated with autonomic functions (e.g., arousal), and olfaction [4]. Furthermore, the limbic system has been found to play a pivotal role in mediating the drives or instincts that assist in the attainment of fundamental biological needs [2]. In terms of the Limbic Systems role in memory, explicit memory, including semantic and episodic memory, represents the domain of memory that is dependent upon the network. However, there is greater reliance on the actions of the Hippocampal formation, Amygdala and Rhinal cortices in comparison to other structures of the Limbic System [3]. In addition, the Prefrontal cortex as well as additional structures of the Temporal lobe that do not fall under the umbrella that is the Limbic System, are linked to the aforementioned domains of memory [3]. Yet, the key component still remains to be the Hippocampal L 890 L Limbitrol formation as it has been specifically linked to memory acquisition [5]. The role of the Hippocampal formation in memory has been best seen in individuals with bilateral injuries of the Hippocampus, such as the classic case of H. M. who following bilateral Hippocampal resection presented with dense anterograde amnesia in which he had severe difficulties in learning new information. Aside from those structures included as part of the network, the Limbic System has also been closely related to the Hypothalamus. It is this connection that provides for the integration and organization of autonomic processes related to the emotional expression of behavior [5]. In terms of those structures viewed as playing more prominent roles in the regulation of emotions, the Cingulate gyrus and Amygdala constitute those of greatest interest. While the Amygdala has been linked to aspects of fear conditioning, in addition to strengthening stored memories by linking emotional cues to the information to be recalled, the Cingulate gyrus plays a vital role in controlling the experience of emotion [2]. Again, this is related to its projections to the Hypothalamus, which is then responsible for directing the autonomic and endocrine effectors of emotion [2]. However, while this relationship and the workings of the Hypothalamus may impact the experience of emotion, higher cortical areas, such as the Frontal lobes, constitute the gateway that in turn determines what behavior is exhibited in response to the emotional experiences. This is the basis of inhibition. Finally, the manner in which the Limbic System is involved in mediating drive and/or instincts for basic survival is largely related to the bidirectional nature of the Limbic-Hypothalamus link. Specifically, while emotional reactivity, as processed by the Limbic system, transmits to the Hypothalamus to mediate concurrent organization of autonomic responses to the emotionally stimulating environment, the Hypothalamus is the starting point in terms of signaling when there is a biological need, this impulse is then passed along to the Limbic System to assist in increasing arousal and processing the nature of the stimuli. References 1. 2. 3. 4. 5. Elias, L. J., & Saucier, D. M. (2006). Neuropsychology: Clinical and experimental foundations. Boston, MA: Pearson Allyn & Bacon. Filley, C. M. (2001). Neurobehavioral Anatomy (2nd ed.). Boulder: University of Colorado Press. Kolb, B., & Whishaw, I. Q. (2003). Fundamentals of human neuropsychology (5th ed.). New York: Worth Publishers. Loring, D. W. (1999). INS dictionary of neuropsychology. New York: Oxford University Press. Zillmer, E. A., & Spiers, M. V. (2001). Principles of neuropsychology. Belmont, CA: Wadsworth/ Thomson Learning. Limbitrol ▶Chlordiazepoxide Limited Play ▶Restrictive Play Linguistic Determinism ▶Whorfian Hypothesis Linguistic Intelligence ▶Gardner’s Theory of Multiple Intelligences Linguistic Relativity ▶Whorfian Hypothesis Literacy STACY A. S. WILLIAMS State University of New York at Albany, Albany, NY, USA Synonyms Book Learning; Learning; Reading/Writing Proficiency; Scholarship Definition Literacy is the ability to articulate one’s thoughts, listen, read and write. Description The National Literacy Trust (NLT), a non-profit organization for the enhancement of an individual’s life through literacy, defines literacy as the ability to speak, listen, read, Literacy and write in order to fulfill one’s potential. The NLTargues that speech, language, and communication skills are essential in developing reading and writing competency [5]. Literacy does not refer to a single ability but to different types and levels of skills. At one end of the spectrum are the early developing skills in young children that are essential to literacy growth. These are referred to in the literature as emergent and early literacy skills. At the other end of the spectrum are the essential skills for functioning adults, identified by the National Assessment of Adult Literacy (NAAL) as prose, document, and quantitative literacy [4]. Much of the research in the last decade has focused primarily on the reading development of young children. According to the most recent National Assessment of Educational Progress (NAEP) report, approximately one fourth of fourth graders fail to exhibit basic levels of reading skills and one tenth of fourth graders fail to demonstrate basic writing skills. In particular, children in low-income households display disproportionate literacy and writing skills [3, 7]. Furthermore, the NAAL 2003 report indicates that there are 11 million adults in the United States who are illiterate. Furthermore, 14% of adults (30 million) are performing below basic at the most simple and concrete literacy level [4]. Emergent and Early Literacy Understanding the multidimensional aspects of literacy is crucial to reducing the illiteracy rate. At the beginning level, researchers often refer to two types of literacy skills that are considered to be the precursors to literacy development: emergent and early literacy. Emergent literacy refers to a broader concept of literacy that starts prior to formal instruction and leads to an awareness of print. Embedded within this concept are specific skills that relate to reading development. These skills are an awareness of print, relationship of print to speech (i.e., understanding the differences between oral and written language), comprehension of text structures (i.e., knowledge of grammar and organization of stories), phonological awareness (i.e., sensitivity and awareness of sounds in oral language), and letter knowledge (i.e., knowledge of the alphabet and related sounds) [2]. The other type of literacy skill, early literacy, refers to the discrete basic skills that are the foundation for reading success. Researchers have examined skills such as letter knowledge, phonological awareness, concepts of print, and naming of letters, colors, and objects to determine acquisition rates and prediction of later achievement [2]. Students are expected to learn the aforementioned skills during the first formal years of education. Knowledge of L letters and phonemic awareness have been found to bear a strong and direct relationship to the success and ease of reading acquisition [1, 6]. This relationship is strong despite the instructional approach used. The predictive strength of these two skills suggests that the letter-tosound relation is of special interest to beginning readers [1]. The letter-to-sound relation is referred to in the literature as phonological awareness, which refers to the sensitivity of sounds in spoken words as well as the ability to manipulate the sounds. Phonological awareness is but one skill within the abilities of phonological processing. The ability to manipulate sounds in oral language encompasses a broad range of skills that are hierarchically arranged. In the beginning, phonological awareness activities may include rhyming or identifying words with similar beginnings or endings. Later phonological activities require more manipulation at the phoneme level (i.e., segmenting or blending activities). Phonological processing abilities include three types of skills: phonological awareness, phonological coding, and retrieval of phonological codes. Phonological coding refers to the ability to hold phonological information in working memory, while retrieval of phonological codes refers to the rate at which an individual can access the phonological information. Each of these processing abilities is implicated in the varying levels of literacy achievement. In addition to being able to manipulate sounds in oral language, knowledge of the written symbols that represent sounds in language is also important. Letter naming fluency in particular has been found to be a good predictor of reading success. The acquisition of letter knowledge typically follows a gradual accumulation of alphabet knowledge from 3 to 7 years old. During the formative years of literacy acquisition, students are learning to read. By the time students reach third grade, they are reading to learn. Accordingly, the building blocks of later years focus primarily on fluency and comprehension. Developing reading fluency is critical to becoming a competent reader. Research suggests that fluent readers are more likely to comprehend what they read and are more likely to seek out reading opportunities [2]. Adult Literacy The skills necessary for developing fluent reading are the building blocks for literacy activities in adulthood. While literacy in earlier years focuses on learning the skills necessary for fluent reading, literacy in teen to adulthood years focuses on functional literacy. The NAAL, in its assessment of adult literacy, addresses prose, document, and quantitative literacy. Prose literacy is defined as the ability to search, comprehend, and use information from 891 L 892 L Literacy Development continuous texts such as news articles and instructional materials. Document literacy is the ability to search, comprehend, and use information from noncontinuous texts such as job applications, maps, and food labels. Quantitative literacy refers to the ability to identify and perform computations using numbers embedded in printed materials (e.g., balancing checkbooks). These literacy tasks require seven types of literacy skills: the ability to search text efficiently, to infer from texts, to decode and read fluently, to apply knowledge, to understand the structure and meaning of sentences, to identify the calculations required to solve a problem, and to perform the calculations [4]. In summary, literacy refers to the range of skills that are essential for an individual to realize his or her potential. It is the ability to understand oral and written materials and communicate one’s intentions clearly. References 1. 2. 3. 4. 5. 6. 7. Adams, M. J. (1990). Beginning to read: Thinking and learning about print. Cambridge, MA: The MIT Press. Daly III, E. J., Chafouleas, S., & Skinner, C. H. (2005). Interventions for reading problems: Designing and evaluating effective strategies. New York: The Guilford Press. Justice, L. M., Kaderavek, J. N., Fan, X., Sofka, A., & Hunt, A. (2009). Accelerating preschoolers’ early literacy development through classroom-based teacher–child storybook reading and explicit print referencing. Language, Speech, and Hearing Services in Schools, 40, 67–85. Kutner, M., Greenberg, E., Jin, Y., Boyle, B., Hsu, Y., & Dunleavy, E. (2007). Literacy in everyday life: Results from the 2003 national assessment of adult literacy (NCES 2007-480). National Center for Education Statistics: U.S. Department of Education, Washington, DC. The National Literacy Trust. (2008). Viewpoint. Literacy Today, 55, 15–17. Turan, F., & Gözde, G. (2008). Early precursor of reading: Acquisition of phonological awareness skills. Educational Sciences: Theory and Practice, 8, 279–284. Walker-Dalhouse, D., & Risko, V. J. (2008). Homelessness, poverty, and children’s literacy development. The Reading Teacher, 62, 84–86. Definition Literacy typically includes the two areas of reading and writing. Literacy development refers to the on-going development of skills needed to successfully communicate through written communication. Description Communication through written texts is a two-sided conversation. Writers capture their thoughts and ideas in written text and the reader actively receives and responds to written texts. Reading for understanding requires an active thinking process that is influenced by the reader’s prior knowledge and experiences [6]. This active thinking process develops over time in a natural state that “mimics children’s natural development of oral language skills” [7]. Literacy development is reported to be a natural process that begins at birth. The “pre-reading stage” [3] or stage 0, involves caretakers reading to, speaking to, and modeling writing. Chall describes this stage as the moment in literacy development where children are acknowledging the surrounding print and spoken language. The next stage is referred to as stage 1. This stage begins in the early primary years when children learn about the alphabetic principle and is referred to as the “Initial Reading or Decoding Stage.” The next stage is referred to as stage 2, which involves readers building automaticity with the associations acquired in stage 1. During stage 2, readers participate in continual practice and are exposed to an abundance of print at an independent or easy level, which assists readers with acquiring automaticity. Stage 3 begins reading to learn during grades 4–8 where children are refining their print skills and stage 4 occurs during the High School years as students are developing multiple perspectives, Finally, stage 5 transpires during college years and beyond. Relevance to Childhood Development Literacy Development ROBERTA SIMNACHER PATE1, STEPHANIE A. GROTE-GARCIA2 Texas A&M University, Corpus Christi, TX, USA 2 University of the Incarnate Word College of Education, Texas A&M University-Corpus Christi, Corpus Christi, TX, USA 1 Synonyms Reading development; Writing development Literacy Development encompasses perspectives inclusive among theorists over the past 80 years, from the 1930s to present. Several different theories of development include: Piaget’s Theory of Cognitive Development (1969), Maturation Theory (1931), Holdaway’s Theory of Literacy Development (1969), Stage Models of Reading (1983), Emergent Literacy Theory (1985), and Family Literacy Theory (1983). The culmination of these theories is relevant to child development as they impact the teachers’ knowledge and understanding of child development. This realm of knowledge is essential in providing appropriate literacy instruction. Lithium References 1. 2. 3. 4. 5. 6. 7. 8. 9. Adams, M. J. (1990). Beginning to read: thinking and learning about print. Cambridge: MIT Press. Barr, R. (1984). Beginning reading instruction: from debate to reformation. In P. D. Pearson (Ed.), Handbook of reading research. New York: Longman. Chall, J. (1983). Stages of reading development. New York: McGraw-Hill. Holdaway, D. (1979). The foundations of literacy. Sydney, Australia: Ashton Scholastic. Distributed by Heinemann, Portsmouth, NH. Morrow, L. M. (2001). Literacy development in the early years (4th ed.). Boston: Allyn & Bacon. National Excellence in Reading Initiative. (2000). Report of the national reading panel: teaching children to read. Washington: National Institute of Child Health and Human Development. Tracey, D. H., & Morrow, L. M. (2006). Lenses on reading: an introduction to theories and models. New York: Guilford. Smith, F. (2004). Understanding reading (6th ed.). Mahwah: Erlbaum. Venezky, R. L. (1995). Literacy. In T. L. Harris & R. E. Hodges (Eds.), The literacy dictionary: the vocabulary of reading and writing. Newark: International Reading Association. Literatherapy ▶Bibliotherapy Literature Based Instruction ▶Whole Language Approach Lithane ▶Cibalith-S Lithane® ▶Lithium L 893 Lithium ANISA FORNOFF Drake University, Ankeny, IA, USA Synonyms Cibalith-S; Eskalith®; Eskalith-CR®; Lithane®; Lithobid®; Lithonate®; Lithotabs® Definition A prescription medication FDA approved for the management of bipolar disorder and treatment of mania in patients with bipolar disorder. Description This medication works in the central nervous system, but the exact way this medication works is not known. Lithium is available in short acting capsules, short acting tablets, and short acting syrup. It is also available in both long acting capsules and tablets. Other reasons this medication may be taken, which are not FDA approved, are as an augmenting agent for depression, aggression, posttraumatic stress disorder, and conduct disorder in children. The recommended starting dose for this medication in short-acting form is 300–600 mg taken three times a day. For long-acting dosage forms, the recommended starting dose is 300–600 mg three times a day or 450–900 mg twice a day. Maximum suggested dose is 1,800 mg a day. Doses for children over the age of 12 are generally similar to doses for adults. This medication should only be taken as directed by a doctor. It may take 1 or 2 weeks to see the effects of this medication. Lithium may be taken with food if it upsets your stomach. It is recommended to limit caffeine intake and avoid drinking alcohol. It is recommended to drink two or three liters of water daily. Use caution in hot weather and in activities that may make you sweat. Inform your doctor if you have heart disease or kidney disease. Also, tell your doctor if you are dehydrated or have low sodium. It is very important that you do not take more of this medication than your doctor prescribed. Your doctor will monitor lithium levels in your blood. The slow release or sustained release products must be taken whole, do not crush or chew. Some side effects are listed here: swelling, changes in heart rhythm, dizziness, sedation, restlessness, headache, fatigue, dry or thinning hair, changes in thyroid function, upset stomach and diarrhea, increase in urination, weight L 894 L Lithizine gain, and blurred vision. Certain side effects may go away during treatment. Tell your doctor immediately if you notice the following: diarrhea, tremors, lack of coordination, muscle weakness, blurred vision, seizures, or slurred speech. These may be signs of an overdose of this medication. If these should occur, seek medical attention immediately. This medication should be stored out of reach of children and pets and away from light, heat, and moisture. Relevance to Childhood Development Lithium is not FDA approved for use in children younger than 12 years old. This medication may cause weakened bones in children. Women should let their doctor know if they are pregnant or planning to become pregnant. This medication has been shown to cause adverse effects to the fetus. Talk with your doctor before breastfeeding. References 1. 2. 3. American Management Association. (2008). AHFS drug information (24th ed., pp. 2629–2638). Maryland: American Society of HealthSystem Pharmacists. Lexi-Drugs Online [database online]. Hudson, OH: Lexi-Comp. Accessed August 26, 2008. Medical Economics Staff. (2007). Advice for the patient: Drug information in lay language. USP DI Vol II. (27th ed., pp. 1006–1008). Kentucky: Thompson Micromedex. Lithonate ▶Cibalith-S Lithonate® ▶Lithium Lithotabs ▶Cibalith-S Lithotabs® ▶Lithium Little People ▶Dwarfism Lithizine ▶Cibalith-S Locke, John ERIN HAMBRICK University of Kansas, Lawrence, KS, USA Lithobid ▶Cibalith-S Lithobid® ▶Lithium Life Dates 1632–1704 Introduction John Locke, an English politician, doctor, and philosopher, was a forerunner of British ▶Empiricism and is referred to by some as the father of cognitive psychology. Locke’s view of the mind and the origin of knowledge and ideas was reductionist and individualistic; he believed that at birth no innate ideas exist and that all knowledge is derived from personal experience. Locke, John L Educational Information Contributions Locke, similar to most wealthy children of his era, was homeschooled until he was granted admission to Westminster school. Westminster was a private grammar school for privileged and intelligent adolescents and was where he became proficient in many different languages, such as Latin and German. Locke was named the Westminster School King’s Scholar and was subsequently granted admission to Oxford University. After achieving his undergraduate degree, Locke received his master’s in medicine and indulged in other educational interests such as philosophy (Locke was especially well read in both Plato and Descartes) and government. By 1650, he had obtained his master’s and decided to stay at Oxford to teach for the next few decades. Though the schools Locke attended largely influenced his education, Locke’s father, Locke’s bent toward travel, and the political zeitgeist of his time had just as large an impact. Locke’s father was a respected political radical who believed in ▶parliament rule (or rule by the people) instead of monarchical rule. Locke grew up in what has been named the “Glorious Revolution”: a time in English history when political unrest and change inspired many to become radical thinkers and to challenge not only political but philosophical hegemony. Locke’s contributions to psychology are prodigious. Locke, in contrast to many of his philosophical contemporaries, abandoned the question of whether or not there is an actual reality and assumed the workings of the mind were real and could be studied. In order to understand the way the mind worked, Locke took an historical, reductionist approach. Locke derived his understanding of knowledge acquisition by breaking knowledge down into its smallest parts (sensory experiences) and by considering the developmental history of each person (at birth people have little or no knowledge and then accumulate it as they develop). Lockean thought marked a philosophical shift from the use of logic to understand reality to empiricism, or the use of systematic observation to understand reality. For example, Locke decided that because at birth we require other people and sensory experiences to grow, that each person is born a blank slate and this blank slate is influenced solely by experience. Or, that all knowledge and ideas are derived from observable, concrete sensory input instead of from innate or genetically predisposed tendencies. Locke asserted that if we are willing to attend to stimuli, then sensory input is acquired passively. Once this input has reached our mind, then our mind actively reflects on (or perceives) the input and associates this new input with previous experiences. This process of reflection and association results in complex thoughts, and throughout our lives we have increasingly more sensory input that gives rise to more complex thoughts and thus more knowledge. Locke’s delineation of the process of association has especially influenced psychology. In cognitive psychology, association has influenced memory research; many cognitive psychologists believe that we retrieve memories by thinking of an idea that is associated with past experiences and/or by having new experiences that are associated with past experiences. In behavior psychology, the principle of association was applied learning theory. Behaviorists assert that we associate certain behaviors with particular outcomes and thus either increase or decrease that behavior depending on that behavior’s associated consequences. Locke’s “blank slate at birth” or “▶tabula rasa” belief also had strong humanitarian implications. To say that each person is born a blank state essentially means that all people are equal at birth. Thus, Locke’s view of the nature of knowledge caused him to antagonize the patriarchal views of his time and possibly jump-start the feminist movement [3]. Also, this belief landed Locke on the nurture side of the ubiquitous nature-nurture debate in psychology, a debate that may never be fully Accomplishments Locke’s most well known accomplishments are his writings, which were largely penned during the 1690s. Locke’s An Essay Concerning Human Understanding has widely influenced philosophical and psychological thought pertaining to the processes of the mind and the origin knowledge. Locke’s Two Treatises on Government was partly a polemic against monarchy and influenced the decision of America’s founding fathers to establish a democracy instead of a monarchy in the New World. Locke also wrote religious pieces, such as Letters Concerning Toleration, which influenced the Protestant Reformation in England and which precipitated America’s laws on the separation of church and state. A lesser-known piece by John Locke is Some Thoughts Concerning Education, which is a compilation of letters Locke wrote to friends on how to parent their children. Though Locke was never a father, he believed that his ideas on knowledge acquisition made him a resource for parents in search of how to help their children develop appropriately. In addition to his writings, Locke was an influential leader at Oxford. He was named the Censor of Moral Philosophy and opened an experimental lab on Oxford’s campus. Though Locke was a trained physician, medicine was more of a hobby to him than a profession. 895 L 896 L Locus Coeruleus resolved but that will always be important to both clinical and experimental work. Possibly the most important contribution Locke had to psychology was his role in founding British Empiricism, a scientific school of thought that believed knowledge can only come from observable experiences. Empiricists also believed that the further one’s conclusions moved from directly observable experiences, the more likely one was to make a thinking error. Though Locke would not have been a proponent of the psychological method of ▶introspection that succeeded him (which depended on the self-report of private, unobservable thoughts), his empirical work did encourage the study of the mind simply because he was one of the first to unequivocally claim that the mind was real and could be studied. Further, several of Locke’s theories on how to raise children are still present in child rearing practices today. For example, because Locke believed that all knowledge is learned via experience, he encouraged parents to provide young children with as many sensory experiences as possible. We now know that certain sensory experiences must be present during critical and sensitive periods in the first years of life to facilitate normal development. In older children, Locke believed knowledge was the path to reason, and that if one had multiple divergent experiences then one would be capable of reasoning in a moral, upright fashion [1]. According to Locke, gaining knowledge via experience was the ultimate path toward righteous, pro-social actions. Thus, Locke influenced many human rights movements. Further, Locke may have influenced person-centered, Humanistic thought by his contention that because everyone has had different sensory experiences, differences between people must be tolerated. Further, Locke thought that when trying to understand and tolerate others we must make an effort to understand their phenomenological worldview. Locke can also be credited for promoting public collections of items, which are today called museums, zoos, and encyclopedias. Because he believed that sensory experiences gave rise to complex ideas, he encouraged collections that would provide experiential learning. 4. 5. 6. Cope, K. L. (1999). John Locke revisited. New York: Twayne. Woolhouse, R. (2007). Locke: A biography. Cambridge: New York. Yolton, J. W. (1985). Lock: An introduction. New York: Basil Blackwell. Locus Coeruleus CHAD A. NOGGLE SIU School of Medicine, Springfield, IL, USA Definition ▶Locus Coeruleus: The Locus Coeruleus is a cluster of neurons in an area of the hindbrain known as the Pons that contains over half of the norepinephrine-based neurons of the central nervous system. Description The Hindbrain represents the lowest and most posterior division of the human brain. The Pons is a structure within the Hindbrain, that in addition to its’ link with motor and sensory action, houses the Locus Coeruleus, which lies just beneath the fourth ventricle. The Locus Coeruleus is a grouping of neurons that contains over half of the Norepinephrine neurons in the Central Nervous System [3]. Norepinephrine is an essential neurotransmitter of the Central nervous System that plays a vital role in regulating sleep-wake cycles, memory, attention, hormones through its influence on the Hypothalamus, Cerebral blood flow, and motor behavior [4]. One of the catecholaminergic neurotransmitters [2], norepinephrine’s influence can be either inhibitory or excitatory [1]. In addition, Norepinephine is commonly indicted with Serotonin in the manifestation of depressive and anxiety disorders as it plays a vital role in the regulation of mood. The holistic impact Norepinephrine has on the CNS is directly related to the widespread ascending noradrenergic projections from the Locus Coeruleus and rostral tegmental area to aspects of the Forebrain, Cerebellum and Spinal Cord [1], that thus correspond with Norepinephrine’s influence on the broad aforementioned functions. References References 1. 1. 2. 3. Benjamin, L. T. (2006). A history of psychology in letters (pp. 15–26). Malden, MA: Blackwell. Billig, M. (2008). The hidden roots of critical psychology (pp. 28–72). Los Angeles, CA: Sage. Butler, M. A. (2007). Early liberal roots of feminism: John Locke’s attack on patriarchy. In N. J. Hirschmann & K. M. McClure (Eds.), Feminist interpretations of John Locke (pp. 91–121). University Park, PA: Pennsylvania State University Press. 2. 3. 4. Blumenfeld, H. (2002). Neuroanatomy through clinical cases. Sunderland, MA: Sinauer Associates. Elias, L. J., & Saucier, D. M. (2006). Neuropsychology: Clinical and experiemental foundations. Boston, MA: Pearson Allyn & Bacon. Loring, D. W. (1999). INS dictionary of neuropsychology. New York: Oxford University Press. Zillmer, E. A., & Spiers, M. V. (2001). Principles of neuropsychology. Belmont, CA: Wadsworth/Thomson Learning. Locus of Control (External and Internal) Locus of Control (External and Internal) DAVID BRANDWEIN Kean University, Union, NJ, USA Synonyms Locus of control reinforcement Definition The internal-external locus of control construct ([8]), describes the extent to which one perceives there to be a causal connection between one’s behavior or cognition and subsequent outcomes. Description The concept of locus of control was developed by ▶Julian Rotter in the 1960s. In looking to bridge two different branches of psychology (behavioral and cognitive), he believed that behavior was greatly influenced by rewards and punishments, and these rewards and punishments shaped how people understand the results of their own actions. Rotter ordered people on a continuum according to how much they attribute the cause of events in their lives to their own actions, motivations, or competencies (internal control) versus how much they assume the cause of these events to be determined by other forces such as luck, chance, or powerful others (external control). Based on Rotter’s conception of locus of control, Nowicki and Strickland [4] developed the Locus of Control Scale for Children, which is still in use today. An important aspect of locus of control has to do with the concept of expectancy, which is related to events that will happen in the future. Locus of control is grounded in expectancy-value theory, which describes human behavior as determined by the perceived likelihood of an event or outcome occurring contingent upon the behavior in question, and the value placed on that event or outcome. More specifically, expectancy-value theory states that if (a) someone values a particular outcome and (b) that person believes that taking a particular action will produce that outcome, then (c) they are more likely to take that particular action. An alternative conception of locus of control was proposed by Levenson [3]. Instead of conceiving locus of control along a one-dimensional continuum (internal to external), Levenson proposed three independent dimensions: Internality, Chance, and Powerful Others. L 897 According to Levenson’s view of locus of control, a person can choose each of these dimensions of locus of control independently as well as together. For example, a person might simultaneously believe that both oneself and powerful others influence outcomes, but that chance does not. Researchers in ▶health psychology have embraced Levinson’s conceptualization, and Wallston, Wallston & Devillis [10] developed the Multidimensional Health Locus of Control Scales to evaluate how locus of control relates to health and illness. Relevance to Childhood Development The variable of locus of control is of significant influence on child behavior and development. Research completed in academic contexts ([2]) found that a belief in destiny was a major determinant in school achievement. In short, internal students feel outcomes (both negative and positive) are derived from a basis of empowerment, whereas external students view such outcomes from a basis of disengagement. Other research ([6]; [9]; [1]) revealed that an external locus of control was associated with increasing tendencies for lower levels of academic achievement, negatively associated with performance in areas of reading, mathematics, and teachers ratings of study habits, and reading attitudes and aptitudes, while internality was found to be a positive factor in predicting academic performance, particularly with regard to attitudes about the reading experience. Locus of control has also been shown to be associated with other psychological characteristics and perceptions. Nunn [5] found significant relationships between an internal locus of control and positive perceptions of adjustment within the home, school, and peer relations., and Nunn & Nunn [7] have also shown that students who are considered at-risk for educational failure have developed more external views of themselves, are more anxious, have lower self-esteem, and exhibit more symptoms of depression than students who are successful. Tesiny et al. [9] also found that external locus of control was significantly associated with both depression scores and academic achievement measures, e.g., reading, math, teacher rating of study habits, and peer nominations of children who exhibited symptoms of depression. References 1. Blaha, J., & Chomin, L. (1982). The relationship of reading attitudes to academic aptitude, locus of control, and field independence. Psychology in the Schools, 19, 28–32. L 898 L Locus of Control Reinforcement 2. Coleman, J. S., Campbell, E. Q., Hobson, C. J., McPartland, J., Mood, A. M., Weinfeld, F. D., et al. (1966). Equality of educational opportunity. Washington DC: United States Office of Education. 3. Levenson, H. (1973). Multidimensional locus of control in psychiatric patients. Journal of Consulting and Clinical Psychology, 41(3), 397–404. 4. Nowicki, S., & Strickland, B. (1973). A locus of control scale for children. Journal of Consulting and Clinical Psychology, 40, 148–154. 5. Nunn, G. D. (1988). The relationship between children’s locus of control and Perceptions of home, school, and peers. Journal of Human Behavior and Learning, 5, 18–21. 6. Nunn, G. D., Montgomery, J. D., & Nunn, S. J. (1986). Criterionrelated validity of the Nowicki-Strickland Locus of Control Scale with academic achievement. Psychology: A Quarterly Journal of Human Behavior, 23, 9–11. 7. Nunn, G. D., & Nunn, S. J. (1993). Locus of control and school performance: some implications for teachers. Education, 113(4), 636–640. 8. Rotter, J. B. (1966). Generalized expectancies for internal versus external control of reinforcement. Psychological Monographs, 80(1, Whole No. 609). 9. Tesiny, E. P., Lefkowitz, M. M., & Gordon, N. H. (1980). Childhood depression, locus of control, and school achievement. Journal of Educational Psychology, 72, 506–510. 10. Wallston, K. A., Wallston, B. S., & Devillis, R. (1978). Development of the multidimensional locus of control scales. Health Education Monographs, 6, 161–170. Lone/Single Parent/Caregiver Families ▶Single Parent Families Longitudinal Methods XENIA ANASTASSIOU-HADJICHARALAMBOUS, MARIA STYLIANOU University of Nicosia, Nicosia, Cyprus Definition The term longitudinal methods represent a research design in which participants are repeatedly assessed over an extended period with repeated evaluations which are often spread across at least several years. Description It is quite common to distinguish between two types of longitudinal designs: the panel study and the cohort study. Locus of Control Reinforcement ▶Locus of Control (External and Internal) Logagraphia ▶Spelling Disabilities Logical Reasoning ▶Critical Thinking Logical-Mathematical Intelligence ▶Gardner’s Theory of Multiple Intelligences Panel Study In the Panel Study a sample, often a national representative sample is evaluated at different points in time [6]. Studies utilizing this approach can potentially reveal behavioral patterns and attitudes that could not be addressed by other designs. Depending on the aim of the study the participants could be evaluated on the assessments on a regular basis (i.e., continuous panel) or on certain assessments during predetermined intervals (i.e., interval panel). This approach allows the utilization of sophisticated statistical analyses that may potentially determine causal influences over time and therefore offers unique information for the investigation of the developmental aspect of a phenomenon. For instance, is parental stress implicated in the child’s development? Is parental psychopathology implicated in the child’s psychopathology? How does it develop? Does anxiety symptomatology precede depressive symptomatology or vice versa? What is the developmental course? An illustration of a panel study is the British Household Panel Study (BHPS) which started in 1991 [8]. The wave 1 panel consisted of a national representative sample of 10, 300 participants in 5, 500 households drawn from 250 areas of Great Britain. Assessments are carried out in an annual basis annually Longitudinal Methods across six main areas of interest: health, household organization, labor market behavior, income and wealth, housing and socioeconomic values. The resulting data base is a key data resource for social science researchers. Cohort Study In a cohort study a sample of at least one cohort (sometimes the entire cohort) is evaluated across at least two points in time [6]. For research purposes, a cohort consists of individuals who share a significant life event or a characteristic within a given time period. This characteristic could be of varied nature. For instance, being born in 1940–1945, having a certain disease, having a certain education, and having a certain employment status and so on. Cohort studies are often a useful alternative to randomized control studies in which ethical concerns are applicable. For example a randomized control study for the investigation of the impact of inept parental discipline practices on the child’s development and well being would be unethical. Consequently an ethical alternative would be to identify parents who generate incompetent practices and follow them across time to determine whether inept parental practices are implicated in the child’s psychopathology. A classic illustration of a cohort study is the National Child Development Study (NCDS) which was initially motivated by the concern for perinatal mortality [9]. The NCDS follows all children born in Great Britain between 3 and 9 March 1958 (about 17,000 participants) and monitors their physical, educational and social development. The study aims to improve understanding of the factors affecting human development over the whole lifespan and it is a popular database for social science research. Advantages The significant advantage of the longitudinal methods lies upon their unique ability to trace developmental trajectories [2, 3]. Given that each individual has his/her unique genetic makeup the longitudinal design allows intraindividual variability to be minimized. Drawbacks A significant drawback of longitudinal methods is the problem of attrition or loss of participants across time due to factors such as decision of participants to withdraw, unexpected life events such as death, movement and so on [7]. The problem with attrition lies in the possibility that the individuals who withdraw from the study may vary in a systematic way from those who remain in the study, making the generalisability of the results hard to L make. For instance in the USA those individuals that are more likely to move from place to place, are at the same time those individuals who derive from lower socio-economic status. Menard [1] refers to a study of adolescent drug abuse in the USA in which 55% of participants withdrew from the study making the results difficult to interpret. Of course attrition rates do not typically reach as high as 55%, but when the attrition is high caution should be exercised in the interpretation of the results. A further problem inherent in the longitudinal design is that a panel conditioning effect is plausible [3–5]. In other words, the possibility that ongoing participation in a longitudinal study could itself potentially affect how participants behave. Menard [1] cites a study of caregiving in families and reports that 52% of the participants reported that their participation in the study drove them toward providing different care for the family. A third problem inherent in the longitudinal methods is the significant financial cost coupled sometimes with poor planning of the design which often results in large data pools without valuable research output. Finally a further shortcoming inherent in the longitudinal methods are the normative and nonnormative changes that occur in society across a given time threshold that are always different to the conditions of another time point in history [3–5]. For instance individuals born in 1940 and followed for 20 years had different historical conditions to those born in 1990 and again followed for 20 years. It is not only the individual that changes, the world itself changes as well. For example, if the results of a longitudinal design found that individuals born between 1990–1995 reported different opinions about energy conservation in the first wave of data collection, that occurred in 2000, in relation to the fourth wave of data collection, that occurred in 2009; Does this indicate a developmental change of these individuals or a change in the world? Consequently in interpretations of the findings of longitudinal designs historical conditions need to be taken into consideration. References 1. 2. 3. 4. 5. Menard, S. (1991). Longitudinal research. Newbury Park, CA: Sage. Davies, R. B., & Pickles, A. R. (1985). Longitudinal versus crosssectional methods for behavioural research: A first-round knockout. Environment and Planning A, 17, 1315–1329. Menard, S. (2002). Longitudinal research (2nd ed.). London: Sage. Ruspini, E. (2002). An introduction to longitudinal research. London: Taylor & Francis. Skinner, C. J. (2003). Introduction to part D: Longitudinal research. In R. L. Chambers & C. J. Skinner (Eds.), Analysis of survey data (pp. 197–204). New York: Wiley. 899 L L 6. 7. 8. 9. Longitudinal Research Hagenaars, J. A. P. (1990). Categorical longitudinal data: Log-linear panel, trend and cohort analysis. Newbury Park, CA: Sage. Taris, T. W. (2000). A primer in longitudinal data analysis. London: Sage. http://www.iser.essex.ac.uk/survey/bhps http://www.esds.ac.uk/longitudinal/access/ncds/ Longitudinal Research AUDREY MCKINLAY University of Canterbury, Christchurch, Canterbury, New Zealand Definition Longitudinal research refers to the analysis of data collected at multiple points in time. points of time. For example, to examine the effects of poor nutrition in early life on aging, data could be collected from a group of young poorly nourished individuals who could then be followed over time. In this example, one of the advantages of using a longitudinal design would be that it would enable the researchers to identify what changes were due to aging compared to those that are due to other factors such as the habits of the individual i.e., smoking. An example of one well known study which uses is longitudinal design is the Baltimore Longitudinal study which was initiated in 1958 and has examined a number of issues related to aging (e.g., [1]). The Baltimore Longitudinal study has over 1,400 volunteers (age between 20–90 years). The aim of this study is to examine what happens as people age. Cross-Sectional Design Description Longitudinal Design Using this longitudinal research it is possible to examine changes over time. As shown by the yellow squares in Fig. 1, in research that uses a longitudinal design a single group of participants is followed and assessed at multiple By comparison, in cross-sectional design information from different subgroups is collected a single point in time (see Fig. 2). A major disadvantage of a cross-sectional design which collects data at a single point in time is that any findings may be compromised by cohort effects. Cohort effects refer to findings that are due to factors e.g., education, religion, or cultural expectations. Time at testing 1945 1955 1965 1975 1985 70–80 Age at testing 900 60–70 50–60 40–50 30–40 0–30 Longitudinal Research. Fig. 1 Shows how a longitudinal design can be used to examine the effects of aging. The participants in this design were first assessed between 0–30 years of age. The same individuals were assessed on five separate occasions, the final assessment taking place when they were between 70–80 years of age. Loss of Ego Boundaries L 901 Time at testing 1945 1955 1965 1975 1985 Age at testing 70–80 60–70 50–60 40–50 30–40 0–30 Longitudinal Research. Fig. 2 Shows how a cross-sectional design can be used to examine the effects of aging. In the design depicted above sub-groups of participants between 0–80 were evaluated at one point in time (1945). L References 1. McCrae, R. R., Costa, P. T., & Arenberg, D. (1980). Constancy of adult personality structure in males: Longitudinal, cross-sectional and times-of-measurement analyses. Journal of Gerontology, 35, 877–883. enhanced synaptic transmission, or the improvement in the ability of two neurons to communicate with oneanother across a synapse. Description Long-Term Effects of Divorce ▶Sleeper Effect of Divorce Long-Term Memory ▶Autobiographical Memory ▶Declarative Memory Long-term potentiation is an example of synaptic plasticity; the ability of the connection, or synapse, between two neurons to change in strength. It may help explain how short-term memories are encoded into long-term memory, as well how some types of human and animal learning occur. Evidence for its role in learning has been found in humans where long-term potentiation has been demonstrated to be characteristic of the cells in the neocortex and hippocampus. References 1. Kolb, B., & Whishaw, I. (2009). Fundamentals of Human Neuropsychology. Worth Publishers: New York, NY. Long-Term Potentiation Definition In neuroscience, long-term potentiation refers to a longlasting change in synapse transmission that results from the simultaneous activation of two neurons. The result is Loss of Ego Boundaries ▶Childhood Psychosis 902 L Loss of Privileges Loss of Privileges ▶Response Cost Loss of Reinforcement ▶Response Cost Lovaas, Ole Ivar JOY JANSEN Neurology, Learning, and Behavior Center, Salt Lake City, UT, USA Contributions Through his work, Dr. Lovaas developed a model known as the Lovaas Model of ABA. The Lovaas Model utilizes the principles of ABA, however, he expands beyond the classic ABA model by considering the time of implementation relative to a child’s unique needs. Current Involvement Currently, Dr. Lovaas is a Professor Emeritus of Psychology and continues to teach at the University of California at Los Angeles (UCLA). In addition, Dr. Lovaas has authored more than 70 publications throughout his career and is the author of two books, Teaching Developmentally Disabled Children: The Me Book in 1981 and, in 2002, wrote, Teaching Individuals With Developmental Delays: Basic Intervention Technique. References Life Dates 1. (1927–Present) 2. Introduction Dr. Lovaas is an internationally-renowned and influential clinical psychologist who has devoted the last forty years in establishing, implementing and evaluating programs to help children with autism develop essential life skills to improve the quality of life. Educational Information Originally from Norway, Dr. Lovaas came to the United States to advance his knowledge and research at the University of Washington, where he received his doctorate of philosophy. Dr. Lovaas’ focus of study was the environment and how it affects behavior and in the early 1950s began working with children with autism. His approach autism was influenced by Dr. Skinner and used the underlying concept of behaviorism, also known applied behavior analysis (ABA). Using the ABA method, Dr. Lovaas has demonstrated, through consistent and dedicated work, ABA is a valuable and effective tool in assisting children with autism as well as children with other psychological conditions. Accomplishments Early in his career Dr. Lovaas founded the Lovaas Institute for Early Intervention (LIFE) and took a professorship at the Unicles (UCLA). LIFE is internationally recognized organization for its success in working with children with autism. Lovaas Institute. (2007). Retrieved October 24, 2007, from http:// www.lovaas.com/ Lovaas, O. I. (1987). Behavioral treatment and normal intellectual and educational functioning in autistic children. Journal of Consulting and Clinical Psychology, 55, 3–9. Low Birth Weight ANNA MAZUR-MOSIEWICZ, RAYMOND S. DEAN Ball State University, Muncie, IN, USA Synonyms LBW Definition Low birth weight (LBW) is defined as a birth weight of 2,500 g or less in a liveborn infant. The LBW infants further subdivided into two groups: very low birth weight (VLBW) infants, who are born with birth weight equal or below 1,500 g, and extremely low birth weight (ELBW) infants, who are born weighting 1,000 g or less [1, 3]. LBW indicates an increased risk of mortality and morbidity. Description Infants with LBW belong to two general categories: infants who have LBW due to premature birth, and infants with Luria, Alexander Romanovich intrauterine growth restriction (low for gestational age), which is typically related to problems with placenta, maternal health, or to birth defects. To differentiate premature LBW from mature growth-retarded LBW several types of data are necessary and include obstetrical history, newborn physical examination, and examination for maturational age. In general, the LBW infants are four times likely than infants born with normal weight to die in their first month of life. These who survive are two to three times more likely to suffer from short and long-term disabilities [2–4]. The percentage of all newborns born with low weight in the United States is around 7%. However, percentage of the LBW infants is higher in minority groups, particularly African-Americans, and the percentage of the AfricanAmerican babies born with LBW is more than double of that for the Caucasian-American newborns [1, 3]. Risk factors for LBW are largely preventable. They include poor maternal nutrition, adolescent pregnancy, use of alcohol and drugs, premature births, smoking, multiple births, and sexually transmitted diseases. The use of assisted reproductive technology additionally accounts for a disproportionate number of LBW and VLBW infants in the United States, which is partially due to increases in multiple gestations and higher rates of LBW among singleton infants conceived with this technology. 903 References 1. 2. 3. 4. 5. Amon, E. (1995). Preterm labor. In E. A. Reece & J. C. Hobbins (Eds.), Medicine of the fetus and mother (pp. 1529–1581). Philadelphia, PA: Lippincott. Hay, J. C., & Persaud, T. V. N. (1999). Normal embryonic and fetal development. In E. A. Reece & J. C. Hobbins (Eds.), Medicine of the fetus and mother (pp. 29–47). Philadelphia, PA: Lippincott. Kabler, J. L., & Delmore, P. M. (1997). Alterations on health status of newborns. In I. F. H. Nichols & E. Zwelling (Eds.), Maternal-newborn nursing: Theory and practice (pp. 1352–1354). Philadelphia, PA: W. B. Saunders Company. Novak, J. C., & Broom, B. L. (1995). Maternal and child health nursing. St Louis, MO: Mosby. Schieve, L. A., Meikle, S. F., Ferre, C., Peterson, H. B., Jeng, G., & Wilcox, L. S. (2002). Low and Very Low Birth Weight in Infants Conceived with Use of Assisted Reproductive Technology. The New England Journal of Medicine, 346, 731–737. Low Social Status Children ▶Rejected Children L Low Socio-Economic Status ▶Inner City Poverty Relevance to Childhood Development Children born with LBW are at high risk of several types of neonatal complications. Generally, the lower the weight of infants, the greater the risk for complications. Clinical problems most commonly associated with LBW are hypothermia; hypoglycemia; aphnea; metabolic acidosis; hypoglycemia; perinatal asphyxia; respiratory problems, particularly the Respiratory Distress Syndrome and aphnea of prematurely; fluid and electrolyte imbalances, which increases risk of dehydration, fluid overload, hypernatremia, hyponatremia, hyperkalemia, hypocalcemia, and hypermagnedemia; hyperbilirubinemia; anemia; impaired nutrition; infections; and sudden infant death syndrome [1, 3, 4]. Additional long-term problems related to LWB include chronic neurological problems such as intraventricular hemorrage, periventricular leukomalacia, and increased risks for cerebral palsy; developmental delay ; ophthalmologic complications; hearing deficits; lung disease; adult-onset diabetes; coronary heart disease; high blood pressure; intellectual problems; sensory disabilities; physical disabilities; and psychological and emotional distress [2, 5]. L Low-Accepted Children ▶Rejected Children Ludes ▶Depressants Luria, Alexander Romanovich DAVID MORRISON, MARY JOANN LANG Azusa Pacific University, Azusa, CA, USA Life Dates (1902–1977) 904 L Luria, Alexander Romanovich Introduction Alexander Romanovich Luria (1902–1977) is a worldrenowned Russian psychologist/scientist who is best known for his theories about localization and cerebral organization of mental functions. Luria’s impact on the Western scientific community continues to be significant three decades after his death. Luria has left an enduring legacy that is widely respected in the scientific community [2]. Although he is often referred to as the father of neuropsychology, this interest developed much later in his professional career. Luria has been widely celebrated and honored outside of the Soviet Union, yet his contributions have not been fully recognized by his native country of Russia [3]. Luria was born in Kazan, Russia in 1902. He died in Moscow of heart failure in 1977. In 1933, Luria married Lana Linchina, also a scientist, and together they had one daughter, Elena Alexandrovna Luria, herself a distinguished microbiologist. Luria is highly regarded in the field of neuropsychology. Despite extraordinary advances in the field of neuroscience, his contributions have been so significant that, according to Tupper [11], he is the most cited soviet scholar in North American literature. Due to this distinction, he is sometimes regarded as the father of neuropsychology. Luria is described by his student, friend and colleague, Goldberg [2] as a “complex man living in a complex time.” A.R. Luria came from a well-educated family. His father and mother were both well-respected physicians. His father taught at the Kazan Medical School. Luria identifies his family as being part of the Russian “intelligentsia.” Luria was greatly impacted by the tumultuous times of pre-revolution Russia and the subsequent chaotic postrevolution cultural shift on Russian society. Luria identifies that the revolution freed the younger generation, regardless of social standing, to explore and discuss new philosophies and social systems. However, Luria indicates that despite the openness to these new opportunities, it was not necessarily conducive to “highly organized scientific inquiry.” Luria’s expansive and shifting intellectual pursuits and interests are considered to be a result of the social and political culture in which he lived [8]. Despite the challenges that confronted him, Luria is considered one of the most influential Soviet scientists of his time. His collaboration with Lev Vygotsky led to extensive and enduring contributions that are recognized throughout the world. Luria is best known for his contributions in developing a comprehensive theory of brain functioning, which remains as the cornerstone for brain-behavior research. His influence in the field of neuropsychology continues to be foundational for many academic programs of study. He is frequently cited in neuropsychology literature, and is best known for his conceptualization of brain organization. However, during the course of his career, his interest went well beyond the more narrow recognition of neuropsychology, and included such areas as child development, educational and rehabilitative interventions, instructional methods, mental retardation, and linguistic phenomena such as aphasia [3, 11]. Educational Information Luria’s education started within the tumultuous political backdrop of the Russian Revolution. From 1912 to 1918 he attended the gymnasium, a secondary school, preparing him for university studies. He completed his secondary studies at the age of 16, at which time he received his diploma. In 1918 he entered Kazan University and pursued studies in the Social Sciences. He describes his studies at Kazan University as being chaotic. He became absorbed with questions concerning man’s role in shaping society. In 1921 he completed his studies in the Social Sciences and continued his studies in the Medical Department of Kazan University. In addition, he pursued his interest in psychology and concurrently enrolled at the Pedagogical Institute, as well as the Kazan Psychiatric Hospital. Luria was influenced by such notable scholars as Sigmund Freud, Alfred Adler, Jung, and Pavlov. His interest in psychoanalytic research led to the formation of the Kazan Psychoanalytic Association. He later joined the staff of the Moscow Institute of Psychology. His work with Vygotsky, which started in 1924, clearly shaped and greatly influenced his life’s work. His regard for Vygotsky as a genius is well documented. Weekly collaborations with Vygotsky, Leontiev and Luria led to the development of research questions in cognitive psychology, such as perception, memory, attention, speech, problem solving, and motor activity. These weekly meetings, known as the “troika,” laid to the foundation for a new comprehensive approach to human psychology, which would incorporate the notion that, as higher processes take shape, the entire structure of behavior is changed [8, 10]. The late 1930s are considered to be a critical turning point in Luria’s career [2]. At this time Luria added a medical degree to his full professorship, became more involved with the biological aspects of psychology, which led to his contributions in neuropsychology. Luria’s interest in cognitive, cultural, and developmental research most certainly influenced his approach to neuropsychology. Luria, Alexander Romanovich Luria returned to Moscow in 1934. At that time, he worked in the Moscow Medical Genetic Institute as head of the Laboratory of Psychology. He also headed the Laboratory of Pathopsychology in the All-Union Institute of Experimental Medicine. His research focus at the Moscow Medical Genetic Institute was on twins, where he studied the role of heredity and external factors in the development of mental processes. World War II was particularly devastating on the citizenry of the Soviet Union. Luria was commissioned to organize a rehabilitation hospital to treat soldiers with brain and peripheral nerve injuries. The task of the hospital had two primary goals: Devise methods of diagnosing local brain lesions and of recognizing and treating complications such as inflammation and secondary infection that were caused by wounds. Second, he was to develop rational, scientifically-based techniques for the rehabilitation of destroyed functions. The extensive and dedicated effort by Luria and his staff led to the development of his theories of brain function and methods for the remediation of focal brain lesions. It was during this time that he developed the systematic approach to the brain and cognition, which has come to be known as the discipline of neuropsychology. Following the war, Luria continued his research activities in neuropsychology. L standardized tests to gauge students’ intelligence. He believed that when exploring what the child knows to determine intellectual ability, it is more beneficial to explore the student’s ability to solve problems independently. Through his efforts, Vygotsky became a major figure in Luria’s life from the beginning of their interactions. Luria’s writings and scientific research were slowly influenced by Vygotsky. Luria based his concepts of higher order psychological functions on the theories of Vygotsky. Luria further expanded on Vygotsky’s model, using qualitative analysis to help both in depth and breadth, in order to further explain higher order thinking that has impacted the fields of neurology, psychology, and neuropsychology [1, 10]. Functional Units of the Brain David E. Tupper, in an article discussing Luria’s influence on worldwide neuropsychology, discussed Luria’s contributions. Basically, according to Tupper, Luria has provided contributions in at least five major areas. These areas include: Cultural-historical Development of Higher Psychological Functions; Functional Units of the Brain; Qualitative Analysis of Neurodynamic Factors; Syndrome Analysis; Systemic Localization of Brain Function, and Verbal Regulation of Behavior [11]. Luria’s most enduring contribution to the field of neuropsychology is his theory on the functional organization of the brain. According to Luria, the brain is made up of three main blocks or functional units incorporating basic functions. Luria conceptualized the cortex as working in the following way: Sensory input enters the primary sensory zones, is elaborated in the secondary zones, and is integrated in the tertiary zones of the sensory, or posterior, unit. Luria (1974, p. 43) also proposed that each of these units is “hierarchical” in structure and consists of at least three cortical zones built one above the other. A primary “projection” area receives impulses. A secondary “projection-association” area processes incoming information and programs information for projection to efferent pathways. The tertiary “zones of overlapping” area is last to develop and is responsible for complex forms of mental activity, which requires the integrated participation of many cortical structures. According to Luria, these units and zones, when functioning properly, work together to regulate all of our behaviors, from waking and sleeping, to hearing and seeing, and thinking and problem solving [4, 5]. Cultural Historical Syndrome Analysis Luria and Vygotsky’s lifespan overlapped 32 years. Vygotsky began his research on issues in education, and focused on the education of handicapped and retarded individuals. He believed in the interaction between the mind (internalized modes of behavior) and the environment. One of Vygotsky’s major theories is titled the zone of proximal development, which discusses the difference between what a student can actually do without help and what he/she can do with help. This model was developed by Vygotsky to argue against the use of One way that Luria assisted in the diagnosis and treatment of patients was his ability to use syndrome analysis (see Luria, 1980, pp. 392.). He was among the first neuropsychologist to clearly state that no simple, unequivocal relation between symptom and localization can be proved. There is, as a rule, no specific way to determine which areas of the cortex could be affected on the basis of a neuropsychological symptom, such as specific disturbances of gnosis or praxis (Online Book). Contributions 905 L 906 L " Luria, Alexander Romanovich If mental activity is a complex functional system, involving the participation of a group of concertedly working areas of the cortex. . .a lesion of each of these zones or areas may lead to disintegration of the entire functional system, and in this way the symptom or “loss” of a particular function tells us nothing about its “localization.” (Luria, 1972, p.35) Understanding neurodynamic factors that may precipitate a patient’s signs and symptoms is facilitated by Luria’s concept of syndrome analysis and qualitative analysis. These applications to clinical thinking provide for a discussion regarding “neurodynamic change.” Currently, this process, with regard to the practice of neuropsychology in North America, is used in concert with a more quantitative approach to understanding brain behavior relationships. Systematic Localization of Brain Function Luria structured the neuropsychological assessment of brain functioning on the basis of a systemic way of thinking. Two questions guide this approach as presented by (Online Book): 1. Which processes are involved in the cognitive functions in consideration? 2. What cerebral structures support the functional system and constitute the neuronal basis for the function in consideration? The relationship between symptom and localization can be very complex. A symptom can result from lesions in both the anterior and posterior cortical areas of the brain [7]. A circumscribed cortical lesion can simultaneously affect many functional systems and, as a result, lead to various manifestations of symptoms. In summary, this concept of complex brain behavior relationships is essential to understand for practitioners and researchers exploring neuropsychological problems and correlating these problems to brain function. Summary It is important to understand the theoretical and methodological differences between a qualitative approach to understanding brain function as proposed by Luria, and the North American approach, which is more quantitative, to understanding brain behavior relationships. Luria based his theories on clinical experience, and his research focused on attempts to develop a theory of neuropsychological functioning based on analyzing and synthesizing information into a meta-theory. Luria often based this process on Vygotsky’s earlier work and theories. In contrast, in North America neuropsychology has been derived from a more psychometric or quantitative approach to understanding brain behavior relationships. Standardized tests are the norm in terms of understanding brain behavior relationships in clinical populations. Despite his disregard for methodological considerations such as standardization, quantification, validation and reliability, several standardized tests have been or are being developed that incorporate both the qualitative approach supported by Luria and the quantitative information that has been historically used in North America [2, 9]. Publications Much of Luria’s work has yet to be translated from Russian to English. The following is a partial list of books that have been translated into English. Ape Primitive Man and Child: Essays in the History of Behavior (1992) Cognitive Development: Its Cultural and Social Foundations (1976) The Making of Mind: A Personal Account of Soviet Psychology (1979) Higher Cortical Functions in Man (1980) The Man With a Shattered World: The History of a Brain Wound (1987) The Mind of a Mnemonist: A Little Book About a Vast Memory (1987) The Human Brain and Psychological Processes (1966) Nature of Human Conflicts (1981) The Neuropsychology of Memory (1976) Traumatic Aphasia: Its Syndromes, Psychology and Treatment (1970) Working Brain: An Introduction to Neuropsychology (1973) References 1. Friedgut-Kotik, B. (2006). Development of the Lurian approach: A cultural neurolinguistic perspective. Neuropsychology Review, 16(1), 43–52. 2. Goldberg, E. (1990). Contemporary neuropsychology and the legacy of Luria. Hillsdale, NJ: L. Erlbaum Associates. 3. Kuzovleva, E., & Das, J. P. (1999). Some facts from the biography of A. R. Luria. Neuropsychology Review, 9(1), 53–56. 4. Languis, M. L., & Miller, D. C. (1992). Luria’s theory of brain functioning: A model for research in cognitive psychophysiology. Educational Psychologist, 27(4), 493–511. 5. Luria, A. R. (1970). The functional organization of the brain. Scientific American, 222(3), 66–78. 6. Luria, A. R. (1972). The man with a shattered world. New York: Basic Books. Lying 7. Luria, A. R. (1974). The working brain: An introduction to neuropsychology. New York: Basic Books. 8. Luria, A. R. (1979). The making of mind: A personal account of Soviet psychology (M. Cole & S. Cole, Trans.). Cambridge, MA: Harvard University Press. 9. Luria, A. R. (1980). Higher cortical functions in man (2nd ed., Rev.). New York: Basic Books. 10. Nell, V. (1999). Luria in Uzbekistan: The vicissitudes of cross cultural neuropsychology. Neuropsychology Review, 9, 45–52. 11. Tupper, D. E. (1999). Introduction: Alexander Luria’s continuing influence on worldwide neuropsychology. Neuropsychology Review, 9(1), 1–7. L 907 Lustprinzip (German) ▶Pleasure Principle Lying ▶Dishonesty L