GUIDE QUESTIONS FOR Unit 2 (Chapters 4 -8) 1. State why DNA is the genetic material. 2. Describe the steps involved during the initiation of transcription. 3. Describe the direction of DNA replication. 4. Describe the major classes of the eukaryotic genomic DNA. 5. How did organelle DNAs evolve? 6. Describe a transcriptionally-inactive chromatin. 7. Describe the molecular events that occur at the lac operon when E. coli cells are shifted from a 8. Describe three types of post-transcriptional regulation of protein-coding genes.