Osteoarthritis, affects 867 million individuals globally and is estimated to impact one in six of all adults, is often the cause of knee pain A Duke University-led team have developed the first cellulose gel-based cartilage substitute that is even stronger and more durable than the Natural cartilage Mechanical testing demonstrates that the hydrogel developed by the Duke researchers, which is composed of water-absorbing polymers, is three times more durable than natural cartilage and can be pressed and pulled with more force. Clinical trial should start as soon as April 2023 Before breaking, natural cartilage can endure a stunning 5,800 to 8,500 pounds per inch of pulling and squishing, respectively. Their lab-created version is the first hydrogel capable of handling even more(deal with 26% more stretching and 66% more squeezing than normal cartilage) https://timesofindia.indiatimes.com/city/hyderabad/89-of-tb-patients-in-t-are-tobacco-usersgovt-report/articleshow/80869853.cms