Section 1: The nature and variety of living organisms a) Characteristics of living organisms What are characteristics that living organisms share? b) Variety of living organisms What is meant by the term pathogen? What are types of pathogen? Examples Features Diagram Type b) Variety of living organisms Can you explain the common features shared by organisms within the following main groups: plants, animals, fungi, bacteria and protoctists? And also explain the features of viruses? Section 2: Structures and functions in living organisms a) Levels of organisation Can you describe the levels of organization within organisms? b) Cell Structure Can you describe the structures of cells and compare the structures of plant and animal cells? b) Cell Structure Can you describe the functions of the different cell structures? Structure Function Found in (animal (A), plant (P), fungi (F), protoctist (Pr), bacteria (B)) Nucleus A, P, F, Pr Cell membrane Cytoplasm Mitochondria Ribosome Cell wall Chloroplasts Vacuole Flagella Plasmid Genetic Material Slime capsule What is meant by cell differentiation? Why is it important in terms of the development of specialised cells? Section 2: Structures and functions in living organisms b) Cell Structure What is meant by cell differentiation? Why is it important in terms of the development of specialised cells? b) Cell Structure How are the following specialised cells found in animals adapted to perform their function? b) Cell Structure How are the following specialised cells found in plants adapted to perform their function? Section 2: Structures and functions in living organisms Biological Molecule Diagram (include units it is made up of): Carbohydrates Monosaccharides Elements: c) Biological Molecules Uses: Test for it: Test for glucose: Disaccharides Test for starch: Polysaccharides/Complex e.g. starch/glycogen/cellulose Proteins Lipids How can the functioning of enzymes be affected by temperature and pH? Can you describe an experiment to investigate how enzyme activity can be affected by changes in temperature? Explain how enzymes work and the factors that affect them: Explain why lipids can be either fats or oils (think saturated vs unsaturated fatty acids): Describe the main similarities and differences between the three main groups of biological molecules (carbohydrates, proteins and lipids) in the body: Section 2: Structures and functions in living organisms d) Movement of substance into and out of cells Can you explain an experiment to investigate diffusion using living and non-living systems? Diffusion: What is diffusion? Osmosis: What is osmosis? How does osmosis differ from diffusion? What affects the rate of diffusion? And how does it affect the rate of diffusion? Explain why each of the following happens in terms of the movement of water: Examples of diffusion: Can you explain an experiment to investigate osmosis using living and non-living systems? Active Transport: What is active transport? What does active transport need? Can you explain the importance of turgid cells in plants? Give some examples of where active transport occurs: Section 2: Structures and functions in living organisms Give the word and symbol equation for photosynthesis: e) Nutrition – Flowering Plants and g) Gas Exchange Explain how you would carry out experiments to investigate photosynthesis, including the evolution of oxygen from a water plant, the production of starch and the requirements of light, carbon dioxide and chlorophyll: How does varying carbon dioxide concentration, light intensity and temperature affect the rate of photosynthesis? Draw a sketch graph to illustrate the effect of each one on the rate of photosynthesis: Can you label the structure of a leaf and explain how it is adapted for photosynthesis and efficient gas exchange? What do plants require mineral ions for? E.g. magnesium and nitrate ions How are they adapted to get mineral ions? Can you explain gas exchange (of carbon dioxide and oxygen) in relation to respiration and photosynthesis? Section 2: Structures and functions in living organisms How do energy requirements vary? e) Nutrition – Humans What are some sources and functions of the following nutrients? Nutrient Explain what is meant by a balanced diet: Carbohydrate Protein Can you describe the processes of: Ingestion: Lipid (fats and oils) Digestion: Vitamin A Absorption: Assimilation: Egestion: Vitamin C Vitamin D Mineral: Calcium Mineral: Iron Explain how and why the food is moved through the gut by peristalsis: Water Fibre Sources Function Section 2: Structures and functions in living organisms e) Nutrition – Humans Label the different parts of the digestive system and explain what happens at each part, including what enzymes are added What are the role of the following digestive enzymes: Enzyme Name Enzyme group it belongs to: Salivary amylase Carbohydrase Source: Substrate: Products: Pancreatic amylase Maltase Pepsin Trypsin Peptidases Lipase Lipase Where is bile produced and stored? What are the roles of bile? How is the small intestine adapted for efficient absorption of the products of digestion? Section 2: Structures and functions in living organisms f) Respiration g) Gas Exchange in humans What are the role of the intercostal muscles and the diaphragm in ventilation? Label the diagram of the breathing system and explain its function: What does the process of respiration do? What does ATP do? What are the differences between aerobic and anaerobic respiration? Aerobic Respiration: Word and balanced symbol equation: Where does aerobic respiration take place? What are the biological consequences of smoking in relation the the lungs and the circulatory system, including coronary heart disease? Anaerobic Respiration: Word and balanced symbol equation in animals: Word and balanced symbol equation in plants: Can you describe experiments to investigate the evolution of carbon dioxide and heat from respiring seeds or other suitable living organisms? How are the alveoli adapted for gas exchange by diffusion between air in the lungs and blood in the capillaries? Can you describe an experiment to investigate the effect of exercise on breathing in humans? Section 2: Structures and functions in living organisms h) Transport and Transport in flowering plants and humans Why can simple, unicellular organisms rely on diffusion for movement of substances in and out of the cell? Describe the components of the blood and give functions of each part: Plasma: What does plasma transport? Why do multicellular organisms need a transport system? Red blood cells: What are the adaptations of red blood cells? What is the role of the phloem? What is the role of the xylem? Platelets: What is the role of platelets in blood clotting? Why is this beneficial? i) Excretion in flowering plants and humans What are the organs of excretion in humans? What are their excretory products? White blood cells: What do white blood cells do? How does the immune system respond to disease? What are phagocytes and lymphocytes and what do they do? What are the waste products in plants and how are they lost? Section 2: Structures and functions in living organisms What causes valves to open and close? Can you explain the difference in structure and function of the arteries, veins and capillaries? h) Transport in humans What is the structure of the heart and how does it work? How is the blood pumped around the body? Explain the passage of blood on one circulation through the body: Can you explain the general structure of the circulation system? Can you explain how the heart rate changes during exercise under the influence of adrenaline? Can you explain how factors may increase the risk of developing coronary heart disease? Section 2: Structures and functions in living organisms j) Co-ordination and response – flowering plants and humans Responses can be controlled by nervous and hormonal communication. What are the differences between the two systems? Nervous system Organisms are able to respond to changes in their environment. - What is homeostasis? Endocrine system - Plant Responses: What does a coordinated response require? How do plants respond to stimuli? Tropism (or trophic response) = What is the central nervous system and how is it linked to sense organs? Phototropism = Geotropism = Can you describe the geotropic and phototropic responses of roots and stems? How does the stimulation of receptors in the sense organs result in rapid responses? Can you explain the role of auxin in the positive phototrophic response of stems? 1) 2) 3) Stimulus ↓ Receptor ↓ Sensory Neurone ↓ Coordinator (CNS) ↓ Motor neurone ↓ Effector ↓ Response Can you describe the structure and function of the eye as a receptor? How does it focus on near and distant objects and respond to changes in light intensity? Section 2: Structures and functions in living organisms What are the sources, roles and effects of the following hormones: j) Co-ordination and response – humans continued Hormone Can you describe the structure and functioning of a simple reflex arc? E.g. withdrawal of a finger from a hot object? Adrenaline Source Role Insulin Testosterone Progesterone Oestrogen Can you describe the role of the skin in temperature regulation? What happens at a synapse? What is the role of neurotransmitters? Effect Section 3a: Reproduction & 3a: Flowering Plants Reproduction Can you describe the structures of a flower and their function? What are the differences between sexual and asexual reproduction? Feature Asexual Reproduction Sexual Reproduction Number of parents Make up of off spring Cell division processes Sex cells produced Fertilisation takes place Variation in offspring Has survival value in: Advantages Disadvantages How can plants reproduce asexually using natural methods? How can plants reproduce asexually using artificial methods? What does fertilisation involve? What is pollination? What is cross-pollination and self-pollination? Section 3a: Flowering Plants Reproduction Can you explain how the growth of the pollen tube followed by fertilisation leads to seed and fruit formation? The ovule forms a ________and the ovary in which it is found becomes a __________. The zygote develops into an ___________with small root (___________) and shoot (___________). The other contents of the ovule develop into ___________ which will be a food store for the young plant when the seed ___________. The ovule wall becomes the ___________ or the ___________. The ovary wall becomes the ___________; this can take many forms depending on the type of fruit. What are the structures of an insect-pollinated flower and a wind-pollinated flower and how are they both adapted for pollination? Feature Insect Wind Petals Scent Nectar Stigma Anthers Pollen grains How can seeds be dispersed? Why are they dispersed? Can you describe a practical that you could use to investigate the conditions needed for seed germination? What are the structures of the seed and why are they important? What are the conditions needed for seed germination? How do germinating seeds utilise food reserves until the seed can carry out photosynthesis? Section 3a: Human Reproduction Can you describe the structure and function of the female reproductive system? Can you describe the structure and function of the male reproductive system? Can you explain the roles of oestrogen and testosterone in developing secondary sexual characteristics and give some examples of these? What are the key stages in sexual reproduction in humans? Section 3a: Human Reproduction Can you explain the roles of oestrogen and progesterone in the menstrual cycle? What is the role of the placenta in the nutrition of the developing embryo? How are sperm cells adapted to carry out their function effectively? How are egg cells adapted to carry out their function effectively? How is the developing embryo protected by the amniotic fluid? Section 3b: Inheritance DNA How is genetic information in a cell stored? DNA What is the structure of a DNA molecule? What is the function of DNA? Genome: Gene: Allele: Dominant: Recessive: Homozygous: Heterozygous: Genotype: Phenotype: Section 3b: Inheritance How is the sex of a person controlled? Draw a punnett square to explain: Differences in the characteristics of individuals of the same kind may be due to differences in: • • • When does the determination of an offpsring’s sex happen? Individuals of a particular species look similar since they inherit similar genes. They look different because their genes are not identical (have different alleles). Classify the following characteristics: Piercings, Physical fitness, tongue rolling, natural eye colour, language spoken, foot size, muscial ability, height, weight, skin colour, natural hair colour, right and left handedness Inherited: Both: Environmental: What is monohybrid inheritance? Use a genetic diagram to describe: Family Pedigrees: useful for tracing family likenesses and inherited diseases. A male is represented by a square. A female is represented by a circle Generally shading indicates the presence of a character in the phenotype Sometimes a dot signifies a normal phenotype but who carries the defective allele. Can you predict the probabilities of outcomes from monohybrid crosses? Most phenotypic features are the result of polygenic inheritance rather than single genes. What does polygenic inheritance mean? What is a mutation? Can you describe the process of evolution by means of natural selection? How has resistance to antibiotics increased in bacterial populations? How does this lead to infections being difficult to control? Section 3b: Inheritance BEFORE CELL DIVISION: __________________ IS REPLICATED. How does sexual reproduction produce genetic variation in offspring? Life Cycle of Humans: In human cells, the haploid number is ______ and the diploid number of chromosomes is _________. Mitosis is the type of cell division that occurs during: • • • • Human cells have ______ pairs of chromosomes in the nucleus. In mitosis, two ________________cells are formed. Both daughter cells have _____________ chromosomes. Cells are __________ ______________– contain exactly the same chromosomes _______________reproduction – offspring produced by mitosis. Draw a diagram to summarise mitosis: Draw a diagram to summarise meiosis: Meiosis is all about the formation of gametes. Human cells have 23 pairs of chromosomes in the nucleus. In meiosis, four slightly different cells are formed. These daughter cells have ___________ chromosomes. Sperm cells (the male ___________) are made in the __________ by meiosis. The egg cells or ova (the female ___________) are made in the ____________ by meiosis. Meiosis leads to four __________ sex cells with ______________ the number of chromosomes. This is so that when _______________ takes place, the __________ has a full set of chromosomes again. Random fertilisation produces genetic __________ of offspring. After fertilisation, the ________ will divide by __________. Section 4: Ecology and the environment a) The organism in the environment What is meant by the following terms: • • • • b) Feeding relationships What is trophic level? What is a producer? population What is a primary, secondary and tertiary consumer? community What is a decomposer? habitat What is a food chain? ecosystem What is a food web? How can quadrats be used to estimate the population size of an organism in two different areas? Why does the level of biomass decrease at each trophic level? What do the arrows show? Pyramids of numbers: Pyramids of biomass: Pyramids of energy transfer: c) Cycles within ecosystems: Can you explain the key stages in the carbon cycle including respiration, photosynthesis, decomposition and combustion? How are substances and energy transferred along a food chain? What is bioaccumulation? Why is only 10% of energy transferred from one trophic level to the next? Section 4: Ecology and the environment c) Cycles within ecosystems: Can you explain the key stages in the carbon cycle: Respiration: • • • • Photosynthesis: Decomposition: Combustion: d) Human influences on the environment The following gases are greenhouse gases: How do human activities contribute to greenhouse gases? • • • • • d) Human influences on the environment What are the biological consequences of pollution of air by sulphur dioxide? How does an increase in greenhouse gases result in enhanced greenhouse effect and how many this lead to global warming? What are the biological consequences of pollution of air by carbon monoxide? What are the biological consequences of pollution of water by sewage? What is eutrophication and what can cause it? What is global warming? Give some consequences of global warming: Section 5: Uses of biological resources a) Food production Crop plants: Micro-organisms How can glasshouses and polythene tunnels be used to increase the yield of certain crops? What conditions are used? What are the role of yeast in the production of beer? Can you describe a simple experiment to investigate carbon dioxide production by yeast, in different conditions? How are fertilisers used to increase crop yield? What is the role of bacteria (Lactobacillus) in the production of yoghurt. What are the reasons for pest control? What are the advantages and disadvantages of using pesticides and biological control with crop plants? Can you label an industrial fermenter and explain the need to provide suitable conditions in the fermenter? Section 5: Uses of biological resources c) Genetic Modification b) Selective breeding How can plants with desired characteristics be developed by selective breeding? What is genetic engineering? • Genetic engineering involves changing the _________ _________ of an organism using the following process: What do restriction enzymes do? What do ligase enzymes do? o o o How can animals with desired characteristics be developed by selective breeding? What is a vector? Give some examples of vectors: What is meant by the term transgenic? Explain what is meant by GM Crops and some examples, as well as why it is important: Can you evaluate the potential for using genetically modified plants to improve food production (use plants with improved resistance to pests as an example): Benefits Concerns How can large amounts of human insulin can be manufactured from genetically modified bacteria that are grown in a fermenter? Required Practicals When planning any investigation what do you need to consider? When drawing any graph what do you need to consider? C S O L R A M P S U 2.12 Practical: Investigate how enzyme activity can be affected by changes in temperature 2.23 Practical: Investigate photosynthesis, showing the evolution of oxygen from a water plant 2.39 Practical: Investigate the evolution of carbon dioxide and heat from respiring seeds or other suitable living organisms 2.23 Practical: Investigate photosynthesis, the production of starch and the requirements of light, carbon dioxide and chlorophyll K 2.9 Practical: Investigate food samples for the presence of glucose, starch, protein and fat Required Practicals 2.50 Practical: investigate breathing in humans, including the release of carbon dioxide and the effect of exercise 5.6 Practical: investigate the role of anaerobic respiration by yeast in different conditions 2.17 practical: investigate diffusion using living and non-living systems 3.5 Practical: investigate the conditions needed for seed germination 2.17 practical: investigate osmosis using living and non-living systems 4.2 Practical: Investigate the population size of an organism in two different areas using quadrats