GERD Pathophysiology Course Pathophysiology Gastro Esophageal Reflux Disease Esophageal - Esophagus Gastro - Stomach Gastroesophageal Reflux Disease Fancy words for heartburn or acid reflux where stomach acids burn the esophagus, leading to pain, inflammation, & even CANCER called Barrett’s esophagus (if the chronic acid reflux is not treated) Dyspepsia “heartBURN” Worse pain = Lying down Causes & Education Anything that can weaken or damage the LES (Lower Esophageal Sphincter) the muscle that closes the opening between the stomach & esophagus. AVOID Eating EXAM TIP ● Fried Foods (Fries, fried chicken) ● Fatty Foods “low fat diet = BEST” ● Citrus (Acidic) ● Dairy (milk, cheese) ● Chocolate ● Peppermint / Spearmint AVOID eating before lying down (3 hours after meals) Sit up after meals Elevate HOB at night Eat Small meals NO Caffeine (coffee) NO Cigarettes (tobacco) NO Alcohol 3 Hours Pharmacology Risk Factors: Stress Obese (BMI over 30) Hiatal hernia Acid reducers ● Antacids ● Histamine receptor blockers Ranitidine ● PPIs: Proton pump inhibitors Omeprazole Procedures Esophagogastroduodenoscopy (EGD) Histamine receptor blockers Diaphragm >30 Peritonitis PRIORITY Report to HCP! ● Fever (over 100.3ᴼF) ● Rebound tenderness ● “Rigid” or “board-like abdomen” Increasing Pain, tenderness Restless ● ● Gastro EGD Esophagogastroduodenoscopy Hiatal hernia Ranitidine ● Duodenal Proton pump inhibitors Acid reducers Complication of Procedures Upper gastrointestinal endoscopy Esophagus Omeprazole Antacid Fast HR & RR (tachycardia / tachypnea) Surgery Stretta procedure - delivers radiofrequency energy waves through electrodes to tighten the LES. Fundoplication - wrap the upper curve of the stomach called the fundus around the esophagus & sew it shut. Helping to tighten this esophageal sphincter.