Infection & Transmission Pathophysiology Course Physiology of infection Incubation: The time from exposure to an infectious agent until the onset of symptoms. Viral or bacterial particles replicate during the incubation stage. Prodromal: The infectious agent continues replicating, which triggers the body’s immune response & mild, nonspecific symptoms (infectious) Acute: Time when a person shows apparent signs & symptoms (manifestations). Local signs Pain, swelling, redness, warmth, exudate Purulent exudate: bacterial infections Serous exudate: viral infections Systemic Signs Top Tested Key Terms Modes of Transmission Vector: insect or animal carrier host Example: Contraction of west Nile virus via mosquito bite Memory Trick Measles Tuberculosis Vector - west nile Virus Aerosol: Small particles from the respiratory tract travel AIRBORNE transmission because droplets are very small and can travel long distances. Example: Measles, Tuberculosis (TB), Varicella, COVID-19 Varicella Covid-19 Memory Trick COVID think CovAIR Droplet: Respiratory or saliva expelled from Pertussis infected individual Fever, fatigue, body aches, headache, nausea Example: Pertussis, Influenza, Meningitis, Pneumonia Direct contact: No intermediary host. Spread via touching of infectious lesions or direct contact with blood/ body secretions. Example: HIV, Herpes, Hepatitis C Influenza Meningitis Memory Trick Incubation Droplet P - Pertussis I - Influenza M - Meningitis P - Pneumonia 1. Surgical Mask & Goggles 2. Single room ATI Teach unlicensed personnel to wear a mask H - coHHHntact Pneumonia Airborne M - Measles T - TB (Tuberculosis) V - Varicella (shingles/chickenpox) 1. N95 mask - Staff 2. Neg. Pressure Room 3. Door closed 4. Transport - Patient wears surgical mask MEMORY TRICK • • On AIR with MTV “PIMP my ride” the old TV show like DROPPing lowrider ON AIR